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Items: 38

1.
2.

Clinical, Genetic, and Biochemical Characteristics of Early-Onset Diabetes in the Finnish Population.

Huopio H, Miettinen PJ, Ilonen J, Nykänen P, Veijola R, Keskinen P, Näntö-Salonen K, Vangipurapu J, Raivo J, Stančáková A, Männistö J, Kuulasmaa T, Knip M, Otonkoski T, Laakso M.

J Clin Endocrinol Metab. 2016 Aug;101(8):3018-26. doi: 10.1210/jc.2015-4296. Epub 2016 May 11.

PMID:
27167055
3.

[Congenital disorder of glycosylation type Ia (CDG Ia) - underdiagnosed entity?].

Sätilä H, Kuusela AL, Pietilä K, Niinikoski H, Keskinen P.

Duodecim. 2016;132(3):253-9. Review. Finnish.

PMID:
26951030
4.

Earlier diagnosis and strict diets improve the survival rate and clinical course of long-chain 3-hydroxyacyl-CoA dehydrogenase deficiency.

Immonen T, Turanlahti M, Paganus A, Keskinen P, Tyni T, Lapatto R.

Acta Paediatr. 2016 May;105(5):549-54. doi: 10.1111/apa.13313. Epub 2016 Feb 5.

PMID:
26676313
5.

[Hypoglycemias as a therapeutic issue in type 1 diabetes?].

Keskinen P, Keskinen P.

Duodecim. 2014;130(12):1245-52. Review. Finnish.

PMID:
25016670
6.

Virus antibody survey in different European populations indicates risk association between coxsackievirus B1 and type 1 diabetes.

Oikarinen S, Tauriainen S, Hober D, Lucas B, Vazeou A, Sioofy-Khojine A, Bozas E, Muir P, Honkanen H, Ilonen J, Knip M, Keskinen P, Saha MT, Huhtala H, Stanway G, Bartsocas C, Ludvigsson J, Taylor K, Hyöty H; VirDiab Study Group.

Diabetes. 2014 Feb;63(2):655-62. doi: 10.2337/db13-0620. Epub 2013 Sep 5.

7.

Insulin secretion and sensitivity in the prediction of type 1 diabetes in children with advanced β-cell autoimmunity.

Siljander HT, Hermann R, Hekkala A, Lähde J, Tanner L, Keskinen P, Ilonen J, Simell O, Veijola R, Knip M.

Eur J Endocrinol. 2013 Sep 14;169(4):479-85. doi: 10.1530/EJE-13-0206. Print 2013 Oct.

PMID:
23904276
8.

Pragmatic controlled trial to prevent childhood obesity in maternity and child health care clinics: pregnancy and infant weight outcomes (the VACOPP Study).

Mustila T, Raitanen J, Keskinen P, Saari A, Luoto R.

BMC Pediatr. 2013 May 20;13:80. doi: 10.1186/1471-2431-13-80.

9.

Behavioral counseling to prevent childhood obesity--study protocol of a pragmatic trial in maternity and child health care.

Mustila T, Keskinen P, Luoto R.

BMC Pediatr. 2012 Jul 3;12:93. doi: 10.1186/1471-2431-12-93.

10.

Academic skills in children with early-onset type 1 diabetes: the effects of diabetes-related risk factors.

Hannonen R, Komulainen J, Riikonen R, Ahonen T, Eklund K, Tolvanen A, Keskinen P, Nuuja A; Study Group.

Dev Med Child Neurol. 2012 May;54(5):457-63.

PMID:
22590723
11.

Lifestyle counseling during pregnancy and offspring weight development until four years of age: follow-up study of a controlled trial.

Mustila T, Raitanen J, Keskinen P, Saari A, Luoto R.

J Negat Results Biomed. 2012 May 8;11:11. doi: 10.1186/1477-5751-11-11.

12.

Lifestyle counselling targeting infant's mother during the child's first year and offspring weight development until 4 years of age: a follow-up study of a cluster RCT.

Mustila T, Raitanen J, Keskinen P, Saari A, Luoto R.

BMJ Open. 2012 Feb 3;2(1):e000624. doi: 10.1136/bmjopen-2011-000624. Print 2012.

13.

GAD65 antigen therapy in recently diagnosed type 1 diabetes mellitus.

Ludvigsson J, Krisky D, Casas R, Battelino T, Castaño L, Greening J, Kordonouri O, Otonkoski T, Pozzilli P, Robert JJ, Veeze HJ, Palmer J, Samuelsson U, Elding Larsson H, Åman J, Kärdell G, Neiderud Helsingborg J, Lundström G, Albinsson E, Carlsson A, Nordvall M, Fors H, Arvidsson CG, Edvardson S, Hanås R, Larsson K, Rathsman B, Forsgren H, Desaix H, Forsander G, Nilsson NÖ, Åkesson CG, Keskinen P, Veijola R, Talvitie T, Raile K, Kapellen T, Burger W, Neu A, Engelsberger I, Heidtmann B, Bechtold S, Leslie D, Chiarelli F, Cicognani A, Chiumello G, Cerutti F, Zuccotti GV, Gomez Gila A, Rica I, Barrio R, Clemente M, López Garcia MJ, Rodriguez M, Gonzalez I, Lopez JP, Oyarzabal M, Reeser HM, Nuboer R, Stouthart P, Bratina N, Bratanic N, de Kerdanet M, Weill J, Ser N, Barat P, Bertrand AM, Carel JC, Reynaud R, Coutant R, Baron S.

N Engl J Med. 2012 Feb 2;366(5):433-42. doi: 10.1056/NEJMoa1107096.

14.

Pediatric Cushing's disease due to pituitary hyperplasia.

Mustila T, Keskinen P, Terho M, Huovinen S, Saha MT.

J Pediatr Endocrinol Metab. 2011;24(3-4):191-2. No abstract available.

PMID:
21648290
15.

[Insulin-induced lipoatrophy in children].

Niinikoski H, Näntö-Salonen K, Ruusu P, Kinnala A, Putto-Laurila A, Toppari J, Keskinen P.

Duodecim. 2010;126(11):1328-32. Finnish.

PMID:
20681357
16.

Risk of hyperammonemic coma in the puerperium: two cases of women with diagnosed and undiagnosed deficiency of urea cycle enzymes.

Tihtonen K, Uotila J, Lähde J, Salo M, Keskinen P.

Acta Obstet Gynecol Scand. 2010 Mar;89(3):404-6. doi: 10.3109/00016340903540646.

PMID:
20102292
17.

Dysregulation of lipid and amino acid metabolism precedes islet autoimmunity in children who later progress to type 1 diabetes.

Oresic M, Simell S, Sysi-Aho M, Näntö-Salonen K, Seppänen-Laakso T, Parikka V, Katajamaa M, Hekkala A, Mattila I, Keskinen P, Yetukuri L, Reinikainen A, Lähde J, Suortti T, Hakalax J, Simell T, Hyöty H, Veijola R, Ilonen J, Lahesmaa R, Knip M, Simell O.

J Exp Med. 2008 Dec 22;205(13):2975-84. doi: 10.1084/jem.20081800. Epub 2008 Dec 15.

18.

Hereditary urea cycle diseases in Finland.

Keskinen P, Siitonen A, Salo M.

Acta Paediatr. 2008 Oct;97(10):1412-9. doi: 10.1111/j.1651-2227.2008.00923.x. Epub 2008 Jul 9.

PMID:
18616627
19.

Pienen imeväisen ohimenevä diabetes.

Keskinen P, Lähde J, Kuusela AL, Saha MT.

Duodecim. 2007;123(19):2335-7. Finnish. No abstract available.

PMID:
18020150
20.

Nephropathy advancing to end-stage renal disease: a novel complication of lysinuric protein intolerance.

Tanner LM, Näntö-Salonen K, Niinikoski H, Jahnukainen T, Keskinen P, Saha H, Kananen K, Helanterä A, Metso M, Linnanvuo M, Huoponen K, Simell O.

J Pediatr. 2007 Jun;150(6):631-4, 634.e1.

PMID:
17517249
21.

Intra-abdominal pressure in severe acute pancreatitis.

Keskinen P, Leppaniemi A, Pettila V, Piilonen A, Kemppainen E, Hynninen M.

World J Emerg Surg. 2007 Jan 17;2:2.

22.

Parental reactions to information about increased genetic risk of type 1 diabetes mellitus in infants.

Simonen P, Korhonen T, Simell T, Keskinen P, Kärkkäinen M, Knip M, Ilonen J, Simell O.

Arch Pediatr Adolesc Med. 2006 Nov;160(11):1131-6.

PMID:
17088516
23.

Familial clustering of beta-cell autoimmunity in initially non-diabetic children.

Kukko M, Toivonen A, Kupila A, Korhonen S, Keskinen P, Veijola R, Virtanen SM, Ilonen J, Simell O, Knip M.

Diabetes Metab Res Rev. 2006 Jan-Feb;22(1):53-8.

PMID:
16100734
24.

Expression of hepatitis C virus core protein inhibits interferon-induced nuclear import of STATs.

Melén K, Fagerlund R, Nyqvist M, Keskinen P, Julkunen I.

J Med Virol. 2004 Aug;73(4):536-47.

PMID:
15221897
25.

[Is type 2 diabetes a threat even for Finnish children?].

Saha MT, Keskinen P, Veijola R, Tapanainen P.

Duodecim. 2003;119(15):1419-23. Finnish. No abstract available.

PMID:
14502817
26.

Intranasally administered insulin intended for prevention of type 1 diabetes--a safety study in healthy adults.

Kupila A, Sipilä J, Keskinen P, Simell T, Knip M, Pulkki K, Simell O.

Diabetes Metab Res Rev. 2003 Sep-Oct;19(5):415-20.

PMID:
12951650
27.

Humoral beta-cell autoimmunity is rare in patients with the congenital rubella syndrome.

Viskari H, Paronen J, Keskinen P, Simell S, Zawilinska B, Zgorniak-Nowosielska I, Korhonen S, Ilonen J, Simell O, Haapala AM, Knip M, Hyöty H.

Clin Exp Immunol. 2003 Sep;133(3):378-83.

28.

Signs of beta-cell autoimmunity and HLA-defined diabetes susceptibility in the Finnish population: the sib cohort from the Type 1 Diabetes Prediction and Prevention Study.

Kukko M, Kimpimäki T, Kupila A, Korhonen S, Kulmala P, Savola K, Simell T, Keskinen P, Ilonen J, Simell O, Knip M.

Diabetologia. 2003 Jan;46(1):65-70. Epub 2002 Dec 18.

PMID:
12637984
29.

A simulation model for estimating direct costs of type 1 diabetes prevention.

Hahl J, Simell T, Kupila A, Keskinen P, Knip M, Ilonen J, Simell O.

Pharmacoeconomics. 2003;21(5):295-303.

PMID:
12627983
30.

First-phase insulin response in young healthy children at genetic and immunological risk for Type I diabetes.

Keskinen P, Korhonen S, Kupila A, Veijola R, Erkkilä S, Savolainen H, Arvilommi P, Simell T, Ilonen J, Knip M, Simell O.

Diabetologia. 2002 Dec;45(12):1639-48. Epub 2002 Oct 30.

PMID:
12488953
31.

Expression of HCV structural proteins impairs IFN-mediated antiviral response.

Keskinen P, Melén K, Julkunen I.

Virology. 2002 Aug 1;299(2):164-71.

32.

Genetic risk determines the emergence of diabetes-associated autoantibodies in young children.

Kupila A, Keskinen P, Simell T, Erkkilä S, Arvilommi P, Korhonen S, Kimpimäki T, Sjöroos M, Ronkainen M, Ilonen J, Knip M, Simell O.

Diabetes. 2002 Mar;51(3):646-51.

33.

The first signs of beta-cell autoimmunity appear in infancy in genetically susceptible children from the general population: the Finnish Type 1 Diabetes Prediction and Prevention Study.

Kimpimäki T, Kupila A, Hämäläinen AM, Kukko M, Kulmala P, Savola K, Simell T, Keskinen P, Ilonen J, Simell O, Knip M.

J Clin Endocrinol Metab. 2001 Oct;86(10):4782-8.

PMID:
11600541
34.

Interferon-induced gene expression and signaling in human hepatoma cell lines.

Melén K, Keskinen P, Lehtonen A, Julkunen I.

J Hepatol. 2000 Nov;33(5):764-72.

PMID:
11097485
35.

Impaired antiviral response in human hepatoma cells.

Keskinen P, Nyqvist M, Sareneva T, Pirhonen J, Melén K, Julkunen I.

Virology. 1999 Oct 25;263(2):364-75.

36.

Regulation of HLA class I and II expression by interferons and influenza A virus in human peripheral blood mononuclear cells.

Keskinen P, Ronni T, Matikainen S, Lehtonen A, Julkunen I.

Immunology. 1997 Jul;91(3):421-9.

37.

Regulation of IFN-alpha/beta, MxA, 2',5'-oligoadenylate synthetase, and HLA gene expression in influenza A-infected human lung epithelial cells.

Ronni T, Matikainen S, Sareneva T, Melén K, Pirhonen J, Keskinen P, Julkunen I.

J Immunol. 1997 Mar 1;158(5):2363-74.

PMID:
9036986
38.

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