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Items: 22

1.

Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.

Chennamadhavuni D, Saavedra-Avila NA, Carreño LJ, Guberman-Pfeffer MJ, Arora P, Yongqing T, Pryce R, Koay HF, Godfrey DI, Keshipeddy S, Richardson SK, Sundararaj S, Lo JH, Wen X, Gascón JA, Yuan W, Rossjohn J, Le Nours J, Porcelli SA, Howell AR.

Cell Chem Biol. 2018 Jul 19;25(7):925. doi: 10.1016/j.chembiol.2018.06.008. No abstract available.

PMID:
30028975
2.

Spindle Assembly Disruption and Cancer Cell Apoptosis with a CLTC-Binding Compound.

Bond MJ, Bleiler M, Harrison LE, Scocchera EW, Nakanishi M, G-Dayanan N, Keshipeddy S, Rosenberg DW, Wright DL, Giardina C.

Mol Cancer Res. 2018 Sep;16(9):1361-1372. doi: 10.1158/1541-7786.MCR-18-0178. Epub 2018 May 16.

PMID:
29769406
3.

Dual Modifications of α-Galactosylceramide Synergize to Promote Activation of Human Invariant Natural Killer T Cells and Stimulate Anti-tumor Immunity.

Chennamadhavuni D, Saavedra-Avila NA, Carreño LJ, Guberman-Pfeffer MJ, Arora P, Yongqing T, Pryce R, Koay HF, Godfrey DI, Keshipeddy S, Richardson SK, Sundararaj S, Lo JH, Wen X, Gascón JA, Yuan W, Rossjohn J, Le Nours J, Porcelli SA, Howell AR.

Cell Chem Biol. 2018 May 17;25(5):571-584.e8. doi: 10.1016/j.chembiol.2018.02.009. Epub 2018 Mar 22. Erratum in: Cell Chem Biol. 2018 Jul 19;25(7):925.

4.

High-mobility-group protein 2 regulated by microRNA-127 and small heterodimer partner modulates pluripotency of mouse embryonic stem cells and liver tumor initiating cells.

Zhao Y, Yang Z, Wu J, Wu R, Keshipeddy SK, Wright D, Wang L.

Hepatol Commun. 2017 Oct;1(8):816-830. doi: 10.1002/hep4.1086. Epub 2017 Aug 28.

5.

Scaling Proteome-Wide Reactions of Activity-Based Probes.

Li S, Diego-Limpin PA, Bajrami B, Keshipeddy S, Lam YW, Deng B, Farrokhi V, McShane AJ, Nemati R, Howell AR, Yao X.

Anal Chem. 2017 Jun 20;89(12):6295-6299. doi: 10.1021/acs.analchem.7b01184. Epub 2017 Jun 5.

PMID:
28570047
6.

Pharmaceutical analysis of a novel propargyl-linked antifolate antibiotic in the mouse.

Hoody J, Alverson JB, Keshipeddy S, Barney PA, Walker L, Anderson AC, Wright DL, Priestley ND.

J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Apr 15;1051:54-59. doi: 10.1016/j.jchromb.2017.02.026. Epub 2017 Mar 6.

7.

Direct Substitution of Arylalkynyl Carbinols Provides Access to Diverse Terminal Acetylene Building Blocks.

G-Dayanandan N, Scocchera EW, Keshipeddy S, Jones HF, Anderson AC, Wright DL.

Org Lett. 2017 Jan 6;19(1):142-145. doi: 10.1021/acs.orglett.6b03438. Epub 2016 Dec 13.

8.

MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked Antifolates.

Reeve SM, Scocchera EW, G-Dayanadan N, Keshipeddy S, Krucinska J, Hajian B, Ferreira J, Nailor M, Aeschlimann J, Wright DL, Anderson AC.

Cell Chem Biol. 2016 Dec 22;23(12):1458-1467. doi: 10.1016/j.chembiol.2016.11.007. Epub 2016 Dec 8.

9.

Propargyl-Linked Antifolates Are Potent Inhibitors of Drug-Sensitive and Drug-Resistant Mycobacterium tuberculosis.

Hajian B, Scocchera E, Keshipeddy S, G-Dayanandan N, Shoen C, Krucinska J, Reeve S, Cynamon M, Anderson AC, Wright DL.

PLoS One. 2016 Aug 31;11(8):e0161740. doi: 10.1371/journal.pone.0161740. eCollection 2016.

10.

Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative Pathogens.

Scocchera E, Reeve SM, Keshipeddy S, Lombardo MN, Hajian B, Sochia AE, Alverson JB, Priestley ND, Anderson AC, Wright DL.

ACS Med Chem Lett. 2016 May 5;7(7):692-6. doi: 10.1021/acsmedchemlett.6b00120. eCollection 2016 Jul 14.

11.

Charged Propargyl-Linked Antifolates Reveal Mechanisms of Antifolate Resistance and Inhibit Trimethoprim-Resistant MRSA Strains Possessing Clinically Relevant Mutations.

Reeve SM, Scocchera E, Ferreira JJ, G-Dayanandan N, Keshipeddy S, Wright DL, Anderson AC.

J Med Chem. 2016 Jul 14;59(13):6493-500. doi: 10.1021/acs.jmedchem.6b00688. Epub 2016 Jun 28.

12.

Atypical natural killer T-cell receptor recognition of CD1d-lipid antigens.

Le Nours J, Praveena T, Pellicci DG, Gherardin NA, Ross FJ, Lim RT, Besra GS, Keshipeddy S, Richardson SK, Howell AR, Gras S, Godfrey DI, Rossjohn J, Uldrich AP.

Nat Commun. 2016 Feb 15;7:10570. doi: 10.1038/ncomms10570.

13.

Nonracemic Antifolates Stereoselectively Recruit Alternate Cofactors and Overcome Resistance in S. aureus.

Keshipeddy S, Reeve SM, Anderson AC, Wright DL.

J Am Chem Soc. 2015 Jul 22;137(28):8983-90. doi: 10.1021/jacs.5b01442. Epub 2015 Jul 8.

14.

Propargyl-linked antifolates are dual inhibitors of Candida albicans and Candida glabrata.

G-Dayanandan N, Paulsen JL, Viswanathan K, Keshipeddy S, Lombardo MN, Zhou W, Lamb KM, Sochia AE, Alverson JB, Priestley ND, Wright DL, Anderson AC.

J Med Chem. 2014 Mar 27;57(6):2643-56. doi: 10.1021/jm401916j. Epub 2014 Mar 6.

15.

Silicon acceleration of a tandem alkene isomerization/electrocyclic ring-opening of 2-methyleneoxetanes to α,β-unsaturated methylketones.

Farber E, Rudnitskaya A, Keshipeddy S, Lao KS, Gascón JA, Howell AR.

J Org Chem. 2013 Nov 15;78(22):11213-20. doi: 10.1021/jo4014645. Epub 2013 Oct 28.

PMID:
24111612
16.

Human and mouse type I natural killer T cell antigen receptors exhibit different fine specificities for CD1d-antigen complex.

Wun KS, Ross F, Patel O, Besra GS, Porcelli SA, Richardson SK, Keshipeddy S, Howell AR, Godfrey DI, Rossjohn J.

J Biol Chem. 2012 Nov 9;287(46):39139-48. doi: 10.1074/jbc.M112.412320. Epub 2012 Sep 20.

17.

Toward a formal synthesis of laureatin: unexpected rearrangements involving cyclic ether nucleophiles.

Keshipeddy S, Martínez I, Castillo BF 2nd, Morton MD, Howell AR.

J Org Chem. 2012 Sep 21;77(18):7883-90. Epub 2012 Sep 5.

PMID:
22913294
18.

Efficient chiral monophosphorus ligands for asymmetric Suzuki-Miyaura coupling reactions.

Tang W, Patel ND, Xu G, Xu X, Savoie J, Ma S, Hao MH, Keshipeddy S, Capacci AG, Wei X, Zhang Y, Gao JJ, Li W, Rodriguez S, Lu BZ, Yee NK, Senanayake CH.

Org Lett. 2012 May 4;14(9):2258-61. doi: 10.1021/ol300659d. Epub 2012 Apr 12.

PMID:
22497425
19.

A molecular basis for the exquisite CD1d-restricted antigen specificity and functional responses of natural killer T cells.

Wun KS, Cameron G, Patel O, Pang SS, Pellicci DG, Sullivan LC, Keshipeddy S, Young MH, Uldrich AP, Thakur MS, Richardson SK, Howell AR, Illarionov PA, Brooks AG, Besra GS, McCluskey J, Gapin L, Porcelli SA, Godfrey DI, Rossjohn J.

Immunity. 2011 Mar 25;34(3):327-39. doi: 10.1016/j.immuni.2011.02.001. Epub 2011 Mar 3.

20.

Efficient monophosphorus ligands for palladium-catalyzed Miyaura borylation.

Tang W, Keshipeddy S, Zhang Y, Wei X, Savoie J, Patel ND, Yee NK, Senanayake CH.

Org Lett. 2011 Mar 18;13(6):1366-9. doi: 10.1021/ol2000556. Epub 2011 Feb 14.

PMID:
21319836
21.

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands.

Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, Richardson SK, Porcelli SA, Howell AR, Hayakawa K, Gapin L, Zajonc DM, Wang PG, Joyce S.

EMBO J. 2009 Dec 2;28(23):3781. doi: 10.1038/emboj.2009.348. No abstract available.

22.

Adaptability of the semi-invariant natural killer T-cell receptor towards structurally diverse CD1d-restricted ligands.

Florence WC, Xia C, Gordy LE, Chen W, Zhang Y, Scott-Browne J, Kinjo Y, Yu KO, Keshipeddy S, Pellicci DG, Patel O, Kjer-Nielsen L, McCluskey J, Godfrey DI, Rossjohn J, Richardson SK, Porcelli SA, Howell AR, Hayakawa K, Gapin L, Zajonc DM, Wang PG, Joyce S.

EMBO J. 2009 Nov 18;28(22):3579-90. doi: 10.1038/emboj.2009.286. Epub 2009 Oct 8. Erratum in: EMBO J. 2009 Dec 2;28(23):3781.

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