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Items: 1 to 50 of 113

1.

VEGF expands erythropoiesis via hypoxia-independent induction of erythropoietin in noncanonical perivascular stromal cells.

Greenwald AC, Licht T, Kumar S, Oladipupo SS, Iyer S, Grunewald M, Keshet E.

J Exp Med. 2019 Jan 7;216(1):215-230. doi: 10.1084/jem.20180752. Epub 2018 Dec 13.

PMID:
30545903
2.

Unique role for dentate gyrus microglia in neuroblast survival and in VEGF-induced activation.

Kreisel T, Wolf B, Keshet E, Licht T.

Glia. 2018 Nov 19. doi: 10.1002/glia.23505. [Epub ahead of print]

PMID:
30453385
3.

Modulation of MKNK2 alternative splicing by splice-switching oligonucleotides as a novel approach for glioblastoma treatment.

Mogilevsky M, Shimshon O, Kumar S, Mogilevsky A, Keshet E, Yavin E, Heyd F, Karni R.

Nucleic Acids Res. 2018 Nov 30;46(21):11396-11404. doi: 10.1093/nar/gky921.

4.

Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells.

Vandekeere S, Dubois C, Kalucka J, Sullivan MR, García-Caballero M, Goveia J, Chen R, Diehl FF, Bar-Lev L, Souffreau J, Pircher A, Kumar S, Vinckier S, Hirabayashi Y, Furuya S, Schoonjans L, Eelen G, Ghesquière B, Keshet E, Li X, Vander Heiden MG, Dewerchin M, Carmeliet P.

Cell Metab. 2018 Oct 2;28(4):573-587.e13. doi: 10.1016/j.cmet.2018.06.009. Epub 2018 Jul 12.

PMID:
30017355
5.

Trained Memory of Human Uterine NK Cells Enhances Their Function in Subsequent Pregnancies.

Gamliel M, Goldman-Wohl D, Isaacson B, Gur C, Stein N, Yamin R, Berger M, Grunewald M, Keshet E, Rais Y, Bornstein C, David E, Jelinski A, Eisenberg I, Greenfield C, Ben-David A, Imbar T, Gilad R, Haimov-Kochman R, Mankuta D, Elami-Suzin M, Amit I, Hanna JH, Yagel S, Mandelboim O.

Immunity. 2018 May 15;48(5):951-962.e5. doi: 10.1016/j.immuni.2018.03.030.

PMID:
29768178
6.

Hyperglycemia Impairs Neutrophil Mobilization Leading to Enhanced Metastatic Seeding.

Fainsod-Levi T, Gershkovitz M, Völs S, Kumar S, Khawaled S, Sagiv JY, Sionov RV, Grunewald M, Keshet E, Granot Z.

Cell Rep. 2017 Nov 28;21(9):2384-2392. doi: 10.1016/j.celrep.2017.11.010.

7.

Conditional islet hypovascularisation does not preclude beta cell expansion during pregnancy in mice.

Staels W, Heremans Y, Leuckx G, Van Gassen N, Salinno C, De Groef S, Cools M, Keshet E, Dor Y, Heimberg H, De Leu N.

Diabetologia. 2017 Jun;60(6):1051-1056. doi: 10.1007/s00125-017-4243-1. Epub 2017 Mar 16.

PMID:
28299380
8.

VEGF preconditioning leads to stem cell remodeling and attenuates age-related decay of adult hippocampal neurogenesis.

Licht T, Rothe G, Kreisel T, Wolf B, Benny O, Rooney AG, Ffrench-Constant C, Enikolopov G, Keshet E.

Proc Natl Acad Sci U S A. 2016 Nov 29;113(48):E7828-E7836. Epub 2016 Nov 14.

9.

VEGF regulates relative allocation of Isl1+ cardiac progenitors to myocardial and endocardial lineages.

He Z, Grunewald M, Dor Y, Keshet E.

Mech Dev. 2016 Nov;142:40-49. doi: 10.1016/j.mod.2016.10.004. Epub 2016 Oct 26.

10.

The vascular niche in adult neurogenesis.

Licht T, Keshet E.

Mech Dev. 2015 Nov;138 Pt 1:56-62. doi: 10.1016/j.mod.2015.06.001. Epub 2015 Jun 20. Review.

11.

State-of-the-Art Methods for Evaluation of Angiogenesis and Tissue Vascularization: A Scientific Statement From the American Heart Association.

Simons M, Alitalo K, Annex BH, Augustin HG, Beam C, Berk BC, Byzova T, Carmeliet P, Chilian W, Cooke JP, Davis GE, Eichmann A, Iruela-Arispe ML, Keshet E, Sinusas AJ, Ruhrberg C, Woo YJ, Dimmeler S; American Heart Association Council on Basic Cardiovascular Sciences and Council on Cardiovascular Surgery and Anesthesia.

Circ Res. 2015 May 22;116(11):e99-132. doi: 10.1161/RES.0000000000000054. Epub 2015 Apr 30. No abstract available.

PMID:
25931450
12.

Vessel maturation schedule determines vulnerability to neuronal injuries of prematurity.

Licht T, Dor-Wollman T, Ben-Zvi A, Rothe G, Keshet E.

J Clin Invest. 2015 Mar 2;125(3):1319-28. doi: 10.1172/JCI79401. Epub 2015 Feb 17.

13.

A transgenic platform for testing drugs intended for reversal of cardiac remodeling identifies a novel 11βHSD1 inhibitor rescuing hypertrophy independently of re-vascularization.

Gordon O, He Z, Gilon D, Gruener S, Pietranico-Cole S, Oppenheim A, Keshet E.

PLoS One. 2014 Mar 25;9(3):e92869. doi: 10.1371/journal.pone.0092869. eCollection 2014.

14.

On-site education of VEGF-recruited monocytes improves their performance as angiogenic and arteriogenic accessory cells.

Avraham-Davidi I, Yona S, Grunewald M, Landsman L, Cochain C, Silvestre JS, Mizrahi H, Faroja M, Strauss-Ayali D, Mack M, Jung S, Keshet E.

J Exp Med. 2013 Nov 18;210(12):2611-25. doi: 10.1084/jem.20120690. Epub 2013 Oct 28.

15.

Short-term overexpression of VEGF-A in mouse beta cells indirectly stimulates their proliferation and protects against diabetes.

De Leu N, Heremans Y, Coppens V, Van Gassen N, Cai Y, D'Hoker J, Magenheim J, Salpeter S, Swisa A, Khalaileh A, Arnold C, Gradwohl G, Van de Casteele M, Keshet E, Dor Y, Heimberg H.

Diabetologia. 2014 Jan;57(1):140-7.

PMID:
24121626
16.

Conditional hypovascularization and hypoxia in islets do not overtly influence adult β-cell mass or function.

D'Hoker J, De Leu N, Heremans Y, Baeyens L, Minami K, Ying C, Lavens A, Chintinne M, Stangé G, Magenheim J, Swisa A, Martens G, Pipeleers D, van de Casteele M, Seino S, Keshet E, Dor Y, Heimberg H.

Diabetes. 2013 Dec;62(12):4165-73. doi: 10.2337/db12-1827. Epub 2013 Aug 23.

17.

Delineating multiple functions of VEGF-A in the adult brain.

Licht T, Keshet E.

Cell Mol Life Sci. 2013 May;70(10):1727-37. doi: 10.1007/s00018-013-1280-x. Epub 2013 Mar 12. Review.

PMID:
23475068
18.

Vascular endothelial growth factor-induced neovascularization rescues cardiac function but not adverse remodeling at advanced ischemic heart disease.

Gordon O, Gilon D, He Z, May D, Lazarus A, Oppenheim A, Keshet E.

Arterioscler Thromb Vasc Biol. 2012 Jul;32(7):1642-51. doi: 10.1161/ATVBAHA.112.248674. Epub 2012 Apr 26.

PMID:
22539593
19.

Vascular endothelial growth factor and vascular homeostasis.

Lazarus A, Keshet E.

Proc Am Thorac Soc. 2011 Nov;8(6):508-11. doi: 10.1513/pats.201102-021MW. Review.

PMID:
22052928
20.

Blood vessels restrain pancreas branching, differentiation and growth.

Magenheim J, Ilovich O, Lazarus A, Klochendler A, Ziv O, Werman R, Hija A, Cleaver O, Mishani E, Keshet E, Dor Y.

Development. 2011 Nov;138(21):4743-52. doi: 10.1242/dev.066548. Epub 2011 Sep 28.

21.

Decrease in VEGF expression induces intussusceptive vascular pruning.

Hlushchuk R, Ehrbar M, Reichmuth P, Heinimann N, Styp-Rekowska B, Escher R, Baum O, Lienemann P, Makanya A, Keshet E, Djonov V.

Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):2836-44. doi: 10.1161/ATVBAHA.111.231811. Epub 2011 Sep 15.

22.

A transgenic model for conditional induction and rescue of portal hypertension reveals a role of VEGF-mediated regulation of sinusoidal fenestrations.

May D, Djonov V, Zamir G, Bala M, Safadi R, Sklair-Levy M, Keshet E.

PLoS One. 2011;6(7):e21478. doi: 10.1371/journal.pone.0021478. Epub 2011 Jul 11.

23.

A perfusion-independent role of blood vessels in determining branching stereotypy of lung airways.

Lazarus A, Del-Moral PM, Ilovich O, Mishani E, Warburton D, Keshet E.

Development. 2011 Jun;138(11):2359-68. doi: 10.1242/dev.060723.

24.

Local retention versus systemic release of soluble VEGF receptor-1 are mediated by heparin-binding and regulated by heparanase.

Sela S, Natanson-Yaron S, Zcharia E, Vlodavsky I, Yagel S, Keshet E.

Circ Res. 2011 Apr 29;108(9):1063-70. doi: 10.1161/CIRCRESAHA.110.239665. Epub 2011 Mar 17.

PMID:
21415391
25.

Reversible modulations of neuronal plasticity by VEGF.

Licht T, Goshen I, Avital A, Kreisel T, Zubedat S, Eavri R, Segal M, Yirmiya R, Keshet E.

Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):5081-6. doi: 10.1073/pnas.1007640108. Epub 2011 Mar 8.

26.

Metabolic homeostasis is maintained in myocardial hibernation by adaptive changes in the transcriptome and proteome.

Mayr M, May D, Gordon O, Madhu B, Gilon D, Yin X, Xing Q, Drozdov I, Ainali C, Tsoka S, Xu Q, Griffiths J, Horrevoets A, Keshet E.

J Mol Cell Cardiol. 2011 Jun;50(6):982-90. doi: 10.1016/j.yjmcc.2011.02.010. Epub 2011 Feb 24.

27.

Entrained pulmonary clocks: epithelium and vasculature keeping pace.

Jesudason EC, Keshet E, Warburton D.

Am J Physiol Lung Cell Mol Physiol. 2010 Oct;299(4):L453-4. doi: 10.1152/ajplung.00263.2010. Epub 2010 Aug 6. No abstract available.

28.

VEGF is required for dendritogenesis of newly born olfactory bulb interneurons.

Licht T, Eavri R, Goshen I, Shlomai Y, Mizrahi A, Keshet E.

Development. 2010 Jan;137(2):261-71. doi: 10.1242/dev.039636.

29.

Uterine DCs are crucial for decidua formation during embryo implantation in mice.

Plaks V, Birnberg T, Berkutzki T, Sela S, BenYashar A, Kalchenko V, Mor G, Keshet E, Dekel N, Neeman M, Jung S.

J Clin Invest. 2008 Dec;118(12):3954-65. doi: 10.1172/JCI36682. Epub 2008 Nov 20.

30.

Prolonged blockade of VEGF family members does not cause identifiable damage to retinal neurons or vessels.

Ueno S, Pease ME, Wersinger DM, Masuda T, Vinores SA, Licht T, Zack DJ, Quigley H, Keshet E, Campochiaro PA.

J Cell Physiol. 2008 Oct;217(1):13-22. doi: 10.1002/jcp.21445.

31.

A novel human-specific soluble vascular endothelial growth factor receptor 1: cell-type-specific splicing and implications to vascular endothelial growth factor homeostasis and preeclampsia.

Sela S, Itin A, Natanson-Yaron S, Greenfield C, Goldman-Wohl D, Yagel S, Keshet E.

Circ Res. 2008 Jun 20;102(12):1566-74. doi: 10.1161/CIRCRESAHA.108.171504. Epub 2008 May 30.

PMID:
18515749
32.

Transgenic system for conditional induction and rescue of chronic myocardial hibernation provides insights into genomic programs of hibernation.

May D, Gilon D, Djonov V, Itin A, Lazarus A, Gordon O, Rosenberger C, Keshet E.

Proc Natl Acad Sci U S A. 2008 Jan 8;105(1):282-7. Epub 2007 Dec 27.

33.

Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development.

Ramasamy SK, Mailleux AA, Gupte VV, Mata F, Sala FG, Veltmaat JM, Del Moral PM, De Langhe S, Parsa S, Kelly LK, Kelly R, Shia W, Keshet E, Minoo P, Warburton D, Bellusci S.

Dev Biol. 2007 Jul 15;307(2):237-47. Epub 2007 May 3.

34.

Decidual NK cells regulate key developmental processes at the human fetal-maternal interface.

Hanna J, Goldman-Wohl D, Hamani Y, Avraham I, Greenfield C, Natanson-Yaron S, Prus D, Cohen-Daniel L, Arnon TI, Manaster I, Gazit R, Yutkin V, Benharroch D, Porgador A, Keshet E, Yagel S, Mandelboim O.

Nat Med. 2006 Sep;12(9):1065-74. Epub 2006 Aug 6.

PMID:
16892062
35.

VEGF-induced adult neovascularization: recruitment, retention, and role of accessory cells.

Grunewald M, Avraham I, Dor Y, Bachar-Lustig E, Itin A, Jung S, Chimenti S, Landsman L, Abramovitch R, Keshet E.

Cell. 2006 Jan 13;124(1):175-89. Erratum in: Cell. 2006 Aug 25;126(4):811. Yung, Steffen [corrected to Jung, Steffen].

36.

VEGF-A signaling through Flk-1 is a critical facilitator of early embryonic lung epithelial to endothelial crosstalk and branching morphogenesis.

Del Moral PM, Sala FG, Tefft D, Shi W, Keshet E, Bellusci S, Warburton D.

Dev Biol. 2006 Feb 1;290(1):177-88. Epub 2005 Dec 22.

37.
38.

Specific induction of tie1 promoter by disturbed flow in atherosclerosis-prone vascular niches and flow-obstructing pathologies.

Porat RM, Grunewald M, Globerman A, Itin A, Barshtein G, Alhonen L, Alitalo K, Keshet E.

Circ Res. 2004 Feb 20;94(3):394-401. Epub 2003 Dec 11.

PMID:
14670840
39.

Survival mechanisms of VEGF and PlGF during microvascular remodeling.

Upalakalin JN, Hemo I, Dehio C, Keshet E, Benjamin LE.

Cold Spring Harb Symp Quant Biol. 2002;67:181-7. Review. No abstract available.

PMID:
12858539
40.

Preventing pathological regression of blood vessels.

Keshet E.

J Clin Invest. 2003 Jul;112(1):27-9. No abstract available.

41.

Induction of vascular networks in adult organs: implications to proangiogenic therapy.

Dor Y, Djonov V, Keshet E.

Ann N Y Acad Sci. 2003 May;995:208-16. Review.

PMID:
12814953
42.

Making vascular networks in the adult: branching morphogenesis without a roadmap.

Dor Y, Djonov V, Keshet E.

Trends Cell Biol. 2003 Mar;13(3):131-6. Review.

PMID:
12628345
43.

VEGF modulates early heart valve formation.

Dor Y, Klewer SE, McDonald JA, Keshet E, Camenisch TD.

Anat Rec A Discov Mol Cell Evol Biol. 2003 Mar;271(1):202-8.

44.

Activated pp60c-Src leads to elevated hypoxia-inducible factor (HIF)-1alpha expression under normoxia.

Karni R, Dor Y, Keshet E, Meyuhas O, Levitzki A.

J Biol Chem. 2002 Nov 8;277(45):42919-25. Epub 2002 Aug 27.

45.

Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice.

Compernolle V, Brusselmans K, Acker T, Hoet P, Tjwa M, Beck H, Plaisance S, Dor Y, Keshet E, Lupu F, Nemery B, Dewerchin M, Van Veldhoven P, Plate K, Moons L, Collen D, Carmeliet P.

Nat Med. 2002 Jul;8(7):702-10. Epub 2002 Jun 10. Erratum in: Nat Med 2002 Nov;8(11):1329.

PMID:
12053176
46.

Conditional switching of VEGF provides new insights into adult neovascularization and pro-angiogenic therapy.

Dor Y, Djonov V, Abramovitch R, Itin A, Fishman GI, Carmeliet P, Goelman G, Keshet E.

EMBO J. 2002 Apr 15;21(8):1939-47.

47.

Identification of a novel hypoxia-inducible factor 1-responsive gene, RTP801, involved in apoptosis.

Shoshani T, Faerman A, Mett I, Zelin E, Tenne T, Gorodin S, Moshel Y, Elbaz S, Budanov A, Chajut A, Kalinski H, Kamer I, Rozen A, Mor O, Keshet E, Leshkowitz D, Einat P, Skaliter R, Feinstein E.

Mol Cell Biol. 2002 Apr;22(7):2283-93.

48.
49.

Gene transfer by viral vectors into blood vessels in a rat model of retinopathy of prematurity.

Chowers I, Banin E, Hemo Y, Porat R, Falk H, Keshet E, Pe'er J, Panet A.

Br J Ophthalmol. 2001 Aug;85(8):991-5.

50.

Vascular endothelial growth factor and vascular adjustments to perturbations in oxygen homeostasis.

Dor Y, Porat R, Keshet E.

Am J Physiol Cell Physiol. 2001 Jun;280(6):C1367-74. Review.

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