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Items: 1 to 50 of 580

1.

Cytokine Profile in Lung Transplant Recipients with Aspergillus spp Colonization.

Herrera S, Gohir W, Foroutan F, Aguilar C, Juvet S, Martinu T, Kumar D, Humar A, Rotstein C, Keshavjee S, Singer LG, Husain S.

Transpl Infect Dis. 2019 Feb 12:e13060. doi: 10.1111/tid.13060. [Epub ahead of print]

PMID:
30753747
2.

CT-guided Microcoil Pulmonary Nodule Localization prior to Video-assisted Thoracoscopic Surgery: Diagnostic Utility and Recurrence-Free Survival.

Rodrigues JCL, Pierre AF, Hanneman K, Cabanero M, Kavanagh J, Waddell TK, Chung TB, Pakkal M, Keshavjee S, Cypel M, Yasufuku K, Nguyen ET.

Radiology. 2019 Feb 5:181674. doi: 10.1148/radiol.2019181674. [Epub ahead of print]

PMID:
30720402
3.

Inactivating hepatitis C virus in donor lungs using light therapies during normothermic ex vivo lung perfusion.

Galasso M, Feld JJ, Watanabe Y, Pipkin M, Summers C, Ali A, Qaqish R, Chen M, Ribeiro RVP, Ramadan K, Pires L, Bagnato VS, Kurachi C, Cherepanov V, Moonen G, Gazzalle A, Waddell TK, Liu M, Keshavjee S, Wilson BC, Humar A, Cypel M.

Nat Commun. 2019 Jan 29;10(1):481. doi: 10.1038/s41467-018-08261-z.

4.

Lentiviral interleukin-10 gene therapy: Safety and questions.

Liu M, Juvet SC, Medin JA, Martinu T, Oishi H, Keshavjee S.

J Thorac Cardiovasc Surg. 2019 Feb;157(2):818-819. doi: 10.1016/j.jtcvs.2018.10.082. No abstract available.

PMID:
30669243
5.

NETs in EVLP perfusate predict clinical outcome of lung transplant recipients.

Caldarone L, Mariscal A, Sage A, Khan M, Juvet S, Martinu T, Zamel R, Cypel M, Liu M, Palaniyar N, Keshavjee S.

Eur Respir J. 2019 Jan 17. pii: 1801736. doi: 10.1183/13993003.01736-2018. [Epub ahead of print] No abstract available.

PMID:
30655281
6.

Simultaneous multiplexed amplicon sequencing and transcriptome profiling in single cells.

Saikia M, Burnham P, Keshavjee SH, Wang MFZ, Heyang M, Moral-Lopez P, Hinchman MM, Danko CG, Parker JSL, De Vlaminck I.

Nat Methods. 2019 Jan;16(1):59-62. doi: 10.1038/s41592-018-0259-9. Epub 2018 Dec 17.

PMID:
30559431
7.

Use of predicted vital status to improve survival analysis of multidrug-resistant tuberculosis cohorts.

Brooks MB, Keshavjee S, Gelmanova I, Zemlyanaya NA, Mitnick CD, Manjourides J.

BMC Med Res Methodol. 2018 Dec 11;18(1):166. doi: 10.1186/s12874-018-0637-0.

8.

Frailty assessment prior to thoracic surgery for lung or esophageal cancer: a feasibility study.

Hirpara DH, Kidane B, Rogalla P, Cypel M, de Perrot M, Keshavjee S, Pierre A, Waddell T, Yasufuku K, Darling GE.

Support Care Cancer. 2018 Nov 14. doi: 10.1007/s00520-018-4547-9. [Epub ahead of print]

PMID:
30426204
9.

Metachronous or synchronous primary lung cancer in the era of computed tomography surveillance.

Wang Y, Yeung JC, Hanna WC, Allison F, Paul NS, Waddell TK, Cypel M, de Perrot ME, Yasufuku K, Keshavjee S, Pierre AF, Darling GE.

J Thorac Cardiovasc Surg. 2018 Oct 6. pii: S0022-5223(18)32556-X. doi: 10.1016/j.jtcvs.2018.09.052. [Epub ahead of print]

PMID:
30392946
10.

Spectrum of chronic lung allograft pathology in a mouse minor-mismatched orthotopic lung transplant model.

Martinu T, Oishi H, Juvet SC, Cypel M, Liu M, Berry GJ, Hwang DM, Keshavjee S.

Am J Transplant. 2019 Jan;19(1):247-258. doi: 10.1111/ajt.15167. Epub 2018 Nov 29.

PMID:
30378739
11.

Echinocandin use in lung transplant recipients.

Al Jishi Y, Rotstein C, Kumar D, Humar A, Singer LG, Keshavjee S, Husain S.

Clin Transplant. 2018 Dec;32(12):e13437. doi: 10.1111/ctr.13437. Epub 2018 Dec 9.

PMID:
30375050
12.

Moving Toward Tuberculosis Elimination: Critical Issues for Research in Diagnostics and Therapeutics for Tuberculosis Infection.

Keshavjee S, Amanullah F, Cattamanchi A, Chaisson R, Dobos KM, Fox GJ, Gendelman HE, Gordon R, Hesseling A, Hoi LV, Kampmann B, Kana B, Khuller G, Lewinsohn DM, Lewinsohn DA, Lin PL, Lu LL, Maartens G, Owen A, Protopopova M, Rengarajan J, Rubin E, Salgame P, Schurr E, Seddon JA, Swindells S, Tobin DM, Udwadia Z, Walzl G, Srinivasan S, Rustomjee R, Nahid P.

Am J Respir Crit Care Med. 2018 Oct 18. doi: 10.1164/rccm.201806-1053PP. [Epub ahead of print]

PMID:
30335466
13.

Porphyrin-High-Density Lipoprotein: A Novel Photosensitizing Nanoparticle for Lung Cancer Therapy.

Ujiie H, Ding L, Fan R, Kato T, Lee D, Fujino K, Kinoshita T, Lee CY, Waddell TK, Keshavjee S, Wilson BC, Zheng G, Chen J, Yasufuku K.

Ann Thorac Surg. 2019 Feb;107(2):369-377. doi: 10.1016/j.athoracsur.2018.08.053. Epub 2018 Oct 11.

PMID:
30316853
14.

Incidence of primary graft dysfunction after lung transplantation is altered by timing of allograft implantation.

Cunningham PS, Maidstone R, Durrington HJ, Venkateswaran RV, Cypel M, Keshavjee S, Gibbs JE, Loudon AS, Chow CW, Ray DW, Blaikley JF.

Thorax. 2018 Oct 9. pii: thoraxjnl-2018-212021. doi: 10.1136/thoraxjnl-2018-212021. [Epub ahead of print]

15.

Influence of lung donor agonal and warm ischemic times on early mortality: Analyses from the ISHLT DCD Lung Transplant Registry.

Levvey B, Keshavjee S, Cypel M, Robinson A, Erasmus M, Glanville A, Hopkins P, Musk M, Hertz M, McCurry K, Van Raemdonck D, Snell G.

J Heart Lung Transplant. 2019 Jan;38(1):26-34. doi: 10.1016/j.healun.2018.08.006. Epub 2018 Aug 11.

PMID:
30297241
16.

Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis.

Collaborative Group for the Meta-Analysis of Individual Patient Data in MDR-TB treatment–2017, Ahmad N, Ahuja SD, Akkerman OW, Alffenaar JC, Anderson LF, Baghaei P, Bang D, Barry PM, Bastos ML, Behera D, Benedetti A, Bisson GP, Boeree MJ, Bonnet M, Brode SK, Brust JCM, Cai Y, Caumes E, Cegielski JP, Centis R, Chan PC, Chan ED, Chang KC, Charles M, Cirule A, Dalcolmo MP, D'Ambrosio L, de Vries G, Dheda K, Esmail A, Flood J, Fox GJ, Fréchet-Jachym M, Fregona G, Gayoso R, Gegia M, Gler MT, Gu S, Guglielmetti L, Holtz TH, Hughes J, Isaakidis P, Jarlsberg L, Kempker RR, Keshavjee S, Khan FA, Kipiani M, Koenig SP, Koh WJ, Kritski A, Kuksa L, Kvasnovsky CL, Kwak N, Lan Z, Lange C, Laniado-Laborín R, Lee M, Leimane V, Leung CC, Leung EC, Li PZ, Lowenthal P, Maciel EL, Marks SM, Mase S, Mbuagbaw L, Migliori GB, Milanov V, Miller AC, Mitnick CD, Modongo C, Mohr E, Monedero I, Nahid P, Ndjeka N, O'Donnell MR, Padayatchi N, Palmero D, Pape JW, Podewils LJ, Reynolds I, Riekstina V, Robert J, Rodriguez M, Seaworth B, Seung KJ, Schnippel K, Shim TS, Singla R, Smith SE, Sotgiu G, Sukhbaatar G, Tabarsi P, Tiberi S, Trajman A, Trieu L, Udwadia ZF, van der Werf TS, Veziris N, Viiklepp P, Vilbrun SC, Walsh K, Westenhouse J, Yew WW, Yim JJ, Zetola NM, Zignol M, Menzies D.

Lancet. 2018 Sep 8;392(10150):821-834. doi: 10.1016/S0140-6736(18)31644-1. Review.

PMID:
30215381
17.

Intraoperative extracorporeal support during lung transplantation in patients bridged with venovenous extracorporeal membrane oxygenation.

Hashimoto K, Hoetzenecker K, Yeung JC, Jeagal L, Donahoe L, Pierre A, de Perrot M, Yasufuku K, Waddell TK, Keshavjee S, Cypel M.

J Heart Lung Transplant. 2018 Dec;37(12):1418-1424. doi: 10.1016/j.healun.2018.07.003. Epub 2018 Sep 5.

PMID:
30193763
18.

Adjuvant lung resection in the management of nontuberculous mycobacterial lung infection: A retrospective matched cohort study.

Aznar ML, Zubrinic M, Siemienowicz M, Hashimoto K, Brode SK, Mehrabi M, Patsios D, Keshavjee S, Marras TK.

Respir Med. 2018 Sep;142:1-6. doi: 10.1016/j.rmed.2018.07.003. Epub 2018 Jul 9.

PMID:
30170795
19.

The role of endobronchial ultrasound-guided transbronchial needle aspiration in stereotactic body radiation therapy for non-small cell lung cancer.

Hashimoto K, Daddi N, Giuliani M, Hope A, Le LW, Czarnecka K, Cypel M, Pierre A, de Perrot M, Darling G, Waddell TK, Keshavjee S, Yasufuku K.

Lung Cancer. 2018 Sep;123:1-6. doi: 10.1016/j.lungcan.2018.06.011. Epub 2018 Jun 11.

PMID:
30089578
20.

Favourable health-related quality of life reported in survivors of thymic malignancies.

Soldera SV, Shakik S, Naik H, Moskovitz M, Chen J, Mittmann N, Xu W, Hope A, Bezjak A, Parajian A, Keshavjee S, Liu G.

Eur J Cardiothorac Surg. 2019 Feb 1;55(2):292-299. doi: 10.1093/ejcts/ezy259.

PMID:
30084958
21.

Pig lung transplant survival model.

Mariscal A, Caldarone L, Tikkanen J, Nakajima D, Chen M, Yeung J, Cypel M, Liu M, Keshavjee S.

Nat Protoc. 2018 Aug;13(8):1814-1828. doi: 10.1038/s41596-018-0019-4.

PMID:
30072720
22.

Ischemia-reperfusion induces death receptor-independent necroptosis via calpain-STAT3 activation in a lung transplant setting.

Kim H, Zamel R, Bai XH, Lu C, Keshavjee S, Keshavjee S, Liu M.

Am J Physiol Lung Cell Mol Physiol. 2018 Oct 1;315(4):L595-L608. doi: 10.1152/ajplung.00069.2018. Epub 2018 Jul 19.

PMID:
30024306
23.

Experience from an American Association for Thoracic Surgery Foundation for Thoracic Surgery Training Fellowship: Lung transplantation in Toronto General Hospital.

Tian D, Keshavjee S.

J Thorac Cardiovasc Surg. 2018 Aug;156(2):929-930. doi: 10.1016/j.jtcvs.2018.04.036. No abstract available.

PMID:
30011774
24.

Introducing the concept of semielective lung transplantation through the use of ex vivo lung perfusion.

Cypel M, Yeung JC, Keshavjee S.

J Thorac Cardiovasc Surg. 2018 Dec;156(6):2350-2352. doi: 10.1016/j.jtcvs.2018.05.056. Epub 2018 Jun 4. No abstract available.

PMID:
29961586
25.

A novel combined ex vivo and in vivo lentiviral interleukin-10 gene delivery strategy at the time of transplantation decreases chronic lung allograft rejection in mice.

Oishi H, Juvet SC, Martinu T, Sato M, Medin JA, Liu M, Keshavjee S.

J Thorac Cardiovasc Surg. 2018 Sep;156(3):1305-1315. doi: 10.1016/j.jtcvs.2018.05.003. Epub 2018 May 29.

PMID:
29937159
26.

Visualizing Heterogeneous Pulmonary Ventilation. Respiratory Failure due to an Anterior Mediastinal Mass.

Desîlets A, Keshavjee S, Goligher EC.

Am J Respir Crit Care Med. 2018 Oct 1;198(7):e88-e89. doi: 10.1164/rccm.201801-0037IM. No abstract available.

PMID:
29924939
27.

Inhibition of regulated necrosis attenuates receptor-interacting protein kinase 1-mediated ischemia-reperfusion injury after lung transplantation.

Kanou T, Ohsumi A, Kim H, Chen M, Bai X, Guan Z, Hwang D, Cypel M, Keshavjee S, Liu M.

J Heart Lung Transplant. 2018 Oct;37(10):1261-1270. doi: 10.1016/j.healun.2018.04.005. Epub 2018 Apr 26.

PMID:
29907500
28.

Identification of risk epitope mismatches associated with de novo donor-specific HLA antibody development in cardiothoracic transplantation.

McCaughan JA, Battle RK, Singh SKS, Tikkanen JM, Moayedi Y, Ross HJ, Singer LG, Keshavjee S, Tinckam KJ.

Am J Transplant. 2018 Dec;18(12):2924-2933. doi: 10.1111/ajt.14951. Epub 2018 Jun 22.

PMID:
29847022
29.

Sequential broncho-alveolar lavages reflect distinct pulmonary compartments: clinical and research implications in lung transplantation.

Levy L, Juvet SC, Boonstra K, Singer LG, Azad S, Joe B, Cypel M, Keshavjee S, Martinu T.

Respir Res. 2018 May 25;19(1):102. doi: 10.1186/s12931-018-0786-z.

30.

Comprehensive outcomes after lung retransplantation: A single-center review.

Halloran K, Aversa M, Tinckam K, Martinu T, Binnie M, Chaparro C, Chow CW, Waddell T, McRae K, Pierre A, de Perrot M, Yasufuku K, Cypel M, Keshavjee S, Singer LG.

Clin Transplant. 2018 Jun;32(6):e13281. doi: 10.1111/ctr.13281. Epub 2018 Jun 3.

PMID:
29754418
31.

Turning Off the Tap: Using the FAST Approach to Stop the Spread of Drug-Resistant Tuberculosis in the Russian Federation.

Miller AC, Livchits V, Ahmad Khan F, Atwood S, Kornienko S, Kononenko Y, Vasilyeva I, Keshavjee S.

J Infect Dis. 2018 Jul 13;218(4):654-658. doi: 10.1093/infdis/jiy190.

32.

Quantitative chest CT for subtyping chronic lung allograft dysfunction and its association with survival.

Horie M, Salazar P, Saito T, Binnie M, Brock K, Yasufuku K, Azad S, Keshavjee S, Martinu T, Paul N.

Clin Transplant. 2018 May;32(5):e13233. doi: 10.1111/ctr.13233. Epub 2018 Apr 10.

PMID:
29637624
33.

miR-145 expression enhances integrin expression in SK-GT-4 cell line by down-regulating c-Myc expression.

Derouet MF, Dakpo E, Wu L, Zehong G, Conner J, Keshavjee S, de Perrot M, Waddell T, Elimova E, Yeung J, Darling GE.

Oncotarget. 2018 Mar 8;9(20):15198-15207. doi: 10.18632/oncotarget.24613. eCollection 2018 Mar 16.

34.

Contemporary Management of Idiopathic Laryngotracheal Stenosis.

Donahoe L, Keshavjee S.

Thorac Surg Clin. 2018 May;28(2):167-175. doi: 10.1016/j.thorsurg.2018.01.011. Review.

PMID:
29627051
35.

Efficacy and Cost of Awake Thoracoscopy and Video-Assisted Thoracoscopic Surgery in the Undiagnosed Pleural Effusion.

McDonald CM, Pierre C, de Perrot M, Darling G, Cypel M, Pierre A, Waddell T, Keshavjee S, Yasufuku K, Czarnecka-Kujawa K.

Ann Thorac Surg. 2018 Aug;106(2):361-367. doi: 10.1016/j.athoracsur.2018.02.044. Epub 2018 Mar 22.

PMID:
29577922
36.

Upregulation of alveolar neutrophil enzymes and long pentraxin-3 in human chronic lung allograft dysfunction subtypes.

Saito T, Liu M, Binnie M, Martinu T, Sato M, Keshavjee S.

J Thorac Cardiovasc Surg. 2018 Jun;155(6):2774-2776.e2. doi: 10.1016/j.jtcvs.2018.02.039. Epub 2018 Feb 23. No abstract available.

PMID:
29573785
37.

A strategy for prevention of fungal infections in lung transplantation: Role of bronchoalveolar lavage fluid galactomannan and fungal culture.

Husain S, Bhaskaran A, Rotstein C, Li Y, Bhimji A, Pavan R, Kumar D, Humar A, Keshavjee S, Singer LG.

J Heart Lung Transplant. 2018 Jul;37(7):886-894. doi: 10.1016/j.healun.2018.02.006. Epub 2018 Feb 16.

PMID:
29548625
38.

Pentraxin 3 deficiency enhances features of chronic rejection in a mouse orthotopic lung transplantation model.

Yoshida M, Oishi H, Martinu T, Hwang DM, Takizawa H, Sugihara J, McKee TD, Bai X, Guana Z, Lua C, Cho HR, Juvet S, Cypel M, Keshavjee S, Liu M.

Oncotarget. 2018 Jan 3;9(9):8489-8501. doi: 10.18632/oncotarget.23902. eCollection 2018 Feb 2.

39.

Effects of Warm Versus Cold Ischemic Donor Lung Preservation on the Underlying Mechanisms of Injuries During Ischemia and Reperfusion.

Iskender I, Cypel M, Martinu T, Chen M, Sakamoto J, Kim H, Yu K, Lin H, Guan Z, Hashimoto K, Waddell TK, Liu M, Keshavjee S.

Transplantation. 2018 May;102(5):760-768. doi: 10.1097/TP.0000000000002140.

PMID:
29470355
40.

Lung in a Box: Ex Vivo Lung Transplantation.

Cotter EKH, Banayan JM, Song TH, Chaney MA, Ko H, Cantu E, Diamond J, Weiss SJ, Cypel M, Keshavjee S.

J Cardiothorac Vasc Anesth. 2018 Aug;32(4):1971-1981. doi: 10.1053/j.jvca.2017.12.019. Epub 2017 Dec 12. No abstract available.

PMID:
29449154
41.

Towards donor lung recovery-gene expression changes during ex vivo lung perfusion of human lungs.

Yeung JC, Zamel R, Klement W, Bai XH, Machuca TN, Waddell TK, Liu M, Cypel M, Keshavjee S.

Am J Transplant. 2018 Jun;18(6):1518-1526. doi: 10.1111/ajt.14700. Epub 2018 Mar 30.

PMID:
29446226
42.

Motile cilia of human airway epithelia contain hedgehog signaling components that mediate noncanonical hedgehog signaling.

Mao S, Shah AS, Moninger TO, Ostedgaard LS, Lu L, Tang XX, Thornell IM, Reznikov LR, Ernst SE, Karp PH, Tan P, Keshavjee S, Abou Alaiwa MH, Welsh MJ.

Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1370-1375. doi: 10.1073/pnas.1719177115. Epub 2018 Jan 22.

43.

Extracorporeal life support as a bridge to lung transplantation-experience of a high-volume transplant center.

Hoetzenecker K, Donahoe L, Yeung JC, Azad S, Fan E, Ferguson ND, Del Sorbo L, de Perrot M, Pierre A, Yasufuku K, Singer L, Waddell TK, Keshavjee S, Cypel M.

J Thorac Cardiovasc Surg. 2018 Mar;155(3):1316-1328.e1. doi: 10.1016/j.jtcvs.2017.09.161. Epub 2017 Nov 22.

PMID:
29248282
44.

Metabolic Profile of Ex Vivo Lung Perfusate Yields Biomarkers for Lung Transplant Outcomes.

Hsin MK, Zamel R, Cypel M, Wishart D, Han B, Keshavjee S, Liu M.

Ann Surg. 2018 Jan;267(1):196-197. doi: 10.1097/SLA.0000000000002016.

PMID:
29240608
45.

Using the Consolidated Framework for Implementation Research to implement and evaluate national surgical planning.

Saluja S, Silverstein A, Mukhopadhyay S, Lin Y, Raykar N, Keshavjee S, Samad L, Meara JG.

BMJ Glob Health. 2017 Jul 13;2(2):e000269. doi: 10.1136/bmjgh-2016-000269. eCollection 2017. Review.

46.

Utility of transthoracic needle biopsy after lung transplantation.

Kavanagh J, Siemienowicz M, Keshavjee S, Rogalla P, Singer L, Kandel S.

Clin Transplant. 2018 Feb;32(2). doi: 10.1111/ctr.13168. Epub 2018 Jan 29.

PMID:
29194758
47.

Experience From the Thoracic Surgery Residents Association Traveling Fellowship: Adult and Pediatric Lung Transplantation in Toronto.

Rajab TK, Van Arsdell G, Keshavjee S.

Ann Thorac Surg. 2017 Dec;104(6):2120-2121. doi: 10.1016/j.athoracsur.2017.05.033. No abstract available.

PMID:
29153791
48.

α1-Anti-trypsin improves function of porcine donor lungs during ex-vivo lung perfusion.

Lin H, Chen M, Tian F, Tikkanen J, Ding L, Andrew Cheung HY, Nakajima D, Wang Z, Mariscal A, Hwang D, Cypel M, Keshavjee S, Liu M.

J Heart Lung Transplant. 2018 May;37(5):656-666. doi: 10.1016/j.healun.2017.09.019. Epub 2017 Oct 2.

PMID:
29153638
49.

Experience from the Thoracic Surgery Residents Association traveling fellowship: Adult and pediatric lung transplantation in Toronto.

Rajab TK, Van Arsdell G, Keshavjee S.

J Thorac Cardiovasc Surg. 2017 Dec;154(6):2153-2154. doi: 10.1016/j.jtcvs.2017.08.038. Epub 2017 Aug 24. No abstract available.

PMID:
29132900
50.

Aspergillus galactomannan detection in exhaled breath condensate compared to bronchoalveolar lavage fluid for the diagnosis of invasive aspergillosis in immunocompromised patients.

Bhimji A, Bhaskaran A, Singer LG, Kumar D, Humar A, Pavan R, Lipton J, Kuruvilla J, Schuh A, Yee K, Minden MD, Schimmer A, Rotstein C, Keshavjee S, Mazzulli T, Husain S.

Clin Microbiol Infect. 2018 Jun;24(6):640-645. doi: 10.1016/j.cmi.2017.09.018. Epub 2017 Sep 29.

PMID:
28970160

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