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Items: 14

1.

Stressed-out ROS take a silent death route.

Kesavardhana S, Kanneganti TD.

Nat Immunol. 2018 Feb;19(2):103-105. doi: 10.1038/s41590-017-0034-6. No abstract available.

PMID:
29348507
2.

A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques.

Jones AT, Chamcha V, Kesavardhana S, Shen X, Beaumont D, Das R, Wyatt LS, LaBranche CC, Stanfield-Oakley S, Ferrari G, Montefiori DC, Moss B, Tomaras GD, Varadarajan R, Amara RR.

J Virol. 2018 Feb 12;92(5). pii: e01796-17. doi: 10.1128/JVI.01796-17. Print 2018 Mar 1.

3.

ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways.

Kuriakose T, Man SM, Subbarao Malireddi RK, Karki R, Kesavardhana S, Place DE, Neale G, Vogel P, Kanneganti TD.

Sci Immunol. 2016 Aug 12;1(2):aag2045. doi: 10.1126/sciimmunol.aag2045. Epub 2016 Aug 12.

PMID:
28783694
4.

ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death.

Kesavardhana S, Kuriakose T, Guy CS, Samir P, Malireddi RKS, Mishra A, Kanneganti TD.

J Exp Med. 2017 Aug 7;214(8):2217-2229. doi: 10.1084/jem.20170550. Epub 2017 Jun 20.

5.

Mechanisms governing inflammasome activation, assembly and pyroptosis induction.

Kesavardhana S, Kanneganti TD.

Int Immunol. 2017 May 1;29(5):201-210. doi: 10.1093/intimm/dxx018. Review.

6.

Glycosylation of the core of the HIV-1 envelope subunit protein gp120 is not required for native trimer formation or viral infectivity.

Rathore U, Saha P, Kesavardhana S, Kumar AA, Datta R, Devanarayanan S, Das R, Mascola JR, Varadarajan R.

J Biol Chem. 2017 Jun 16;292(24):10197-10219. doi: 10.1074/jbc.M117.788919. Epub 2017 Apr 26.

7.

NLRC3 is an inhibitory sensor of PI3K-mTOR pathways in cancer.

Karki R, Man SM, Malireddi RK, Kesavardhana S, Zhu Q, Burton AR, Sharma BR, Qi X, Pelletier S, Vogel P, Rosenstiel P, Kanneganti TD.

Nature. 2016 Dec 12. doi: 10.1038/nature20597. [Epub ahead of print]

8.

ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways.

Kuriakose T, Man SM, Malireddi RK, Karki R, Kesavardhana S, Place DE, Neale G, Vogel P, Kanneganti TD.

Sci Immunol. 2016 Aug 5;1(2). pii: aag2045. Epub 2016 Aug 12.

9.

Structure-based Design of Cyclically Permuted HIV-1 gp120 Trimers That Elicit Neutralizing Antibodies.

Kesavardhana S, Das R, Citron M, Datta R, Ecto L, Srilatha NS, DiStefano D, Swoyer R, Joyce JG, Dutta S, LaBranche CC, Montefiori DC, Flynn JA, Varadarajan R.

J Biol Chem. 2017 Jan 6;292(1):278-291. doi: 10.1074/jbc.M116.725614. Epub 2016 Nov 22.

10.

IRGB10 Liberates Bacterial Ligands for Sensing by the AIM2 and Caspase-11-NLRP3 Inflammasomes.

Man SM, Karki R, Sasai M, Place DE, Kesavardhana S, Temirov J, Frase S, Zhu Q, Malireddi RKS, Kuriakose T, Peters JL, Neale G, Brown SA, Yamamoto M, Kanneganti TD.

Cell. 2016 Oct 6;167(2):382-396.e17. doi: 10.1016/j.cell.2016.09.012. Epub 2016 Sep 29.

11.

Stabilizing the native trimer of HIV-1 Env by destabilizing the heterodimeric interface of the gp41 postfusion six-helix bundle.

Kesavardhana S, Varadarajan R.

J Virol. 2014 Sep 1;88(17):9590-604. doi: 10.1128/JVI.00494-14. Epub 2014 Jun 11.

12.

Immunogen design for HIV-1 and influenza.

Rathore U, Kesavardhana S, Mallajosyula VV, Varadarajan R.

Biochim Biophys Acta. 2014 Nov;1844(11):1891-1906. doi: 10.1016/j.bbapap.2014.05.010. Epub 2014 Jun 2. Review.

PMID:
24892211
13.

Smart polymer mediated purification and recovery of active proteins from inclusion bodies.

Gautam S, Dubey P, Singh P, Kesavardhana S, Varadarajan R, Gupta MN.

J Chromatogr A. 2012 Apr 27;1235:10-25. doi: 10.1016/j.chroma.2012.02.048. Epub 2012 Mar 3.

PMID:
22425208
14.

Designed cyclic permutants of HIV-1 gp120: implications for envelope trimer structure and immunogen design.

Saha P, Bhattacharyya S, Kesavardhana S, Miranda ER, Ali PS, Sharma D, Varadarajan R.

Biochemistry. 2012 Mar 6;51(9):1836-47. doi: 10.1021/bi300003v. Epub 2012 Feb 22.

PMID:
22329717

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