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Items: 49

1.

Symptoms and Dietary Impact in Hypertriglyceridemia-Associated Pancreatitis: Development and Content Validity of Two New Measures.

Burbridge C, Randall JA, Sanchez RJ, Dansky H, Symonds T, Girman CJ, Strayer JA, Selk KL, Whitcomb DC, Kershaw EE.

Pharmacoecon Open. 2019 Jun 27. doi: 10.1007/s41669-019-0155-y. [Epub ahead of print]

2.

Wnt Pathway Inhibitor DKK1: A Potential Novel Biomarker for Adiposity.

Ali H, Zmuda JM, Cvejkus RK, Kershaw EE, Kuipers AL, Oczypok EA, Wheeler V, Bunker CH, Miljkovic I.

J Endocr Soc. 2019 Jan 3;3(2):488-495. doi: 10.1210/js.2018-00325. eCollection 2019 Feb 1.

3.

Adipose tissue-derived free fatty acids initiate myeloid cell accumulation in mouse liver in states of lipid oversupply.

Harmon DB, Wu C, Dedousis N, Sipula IJ, Stefanovic-Racic M, Schoiswohl G, O'Donnell CP, Alonso LC, Kershaw EE, Kelley EE, O'Doherty RM.

Am J Physiol Endocrinol Metab. 2018 Nov 1;315(5):E758-E770. doi: 10.1152/ajpendo.00172.2018. Epub 2018 Aug 7.

PMID:
30086648
4.

Atglistatin ameliorates functional decline in heart failure via adipocyte-specific inhibition of adipose triglyceride lipase.

Parajuli N, Takahara S, Matsumura N, Kim TT, Ferdaoussi M, Migglautsch AK, Zechner R, Breinbauer R, Kershaw EE, Dyck JRB.

Am J Physiol Heart Circ Physiol. 2018 Oct 1;315(4):H879-H884. doi: 10.1152/ajpheart.00308.2018. Epub 2018 Jun 22.

PMID:
29932770
5.

Jak-TGFβ cross-talk links transient adipose tissue inflammation to beige adipogenesis.

Babaei R, Schuster M, Meln I, Lerch S, Ghandour RA, Pisani DF, Bayindir-Buchhalter I, Marx J, Wu S, Schoiswohl G, Billeter AT, Krunic D, Mauer J, Lee YH, Granneman JG, Fischer L, Müller-Stich BP, Amri EZ, Kershaw EE, Heikenwälder M, Herzig S, Vegiopoulos A.

Sci Signal. 2018 Apr 24;11(527). pii: eaai7838. doi: 10.1126/scisignal.aai7838.

PMID:
29692363
6.

Brown adipose tissue whitening leads to brown adipocyte death and adipose tissue inflammation.

Kotzbeck P, Giordano A, Mondini E, Murano I, Severi I, Venema W, Cecchini MP, Kershaw EE, Barbatelli G, Haemmerle G, Zechner R, Cinti S.

J Lipid Res. 2018 May;59(5):784-794. doi: 10.1194/jlr.M079665. Epub 2018 Mar 29.

7.

Adipose tissue ATGL modifies the cardiac lipidome in pressure-overload-induced left ventricular failure.

Salatzki J, Foryst-Ludwig A, Bentele K, Blumrich A, Smeir E, Ban Z, Brix S, Grune J, Beyhoff N, Klopfleisch R, Dunst S, Surma MA, Klose C, Rothe M, Heinzel FR, Krannich A, Kershaw EE, Beule D, Schulze PC, Marx N, Kintscher U.

PLoS Genet. 2018 Jan 10;14(1):e1007171. doi: 10.1371/journal.pgen.1007171. eCollection 2018 Jan.

8.

Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue.

Schreiber R, Diwoky C, Schoiswohl G, Feiler U, Wongsiriroj N, Abdellatif M, Kolb D, Hoeks J, Kershaw EE, Sedej S, Schrauwen P, Haemmerle G, Zechner R.

Cell Metab. 2017 Nov 7;26(5):753-763.e7. doi: 10.1016/j.cmet.2017.09.004. Epub 2017 Oct 5.

9.

Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis.

Simcox J, Geoghegan G, Maschek JA, Bensard CL, Pasquali M, Miao R, Lee S, Jiang L, Huck I, Kershaw EE, Donato AJ, Apte U, Longo N, Rutter J, Schreiber R, Zechner R, Cox J, Villanueva CJ.

Cell Metab. 2017 Sep 5;26(3):509-522.e6. doi: 10.1016/j.cmet.2017.08.006.

10.

Single-Step qPCR and dPCR Detection of Diverse CRISPR-Cas9 Gene Editing Events In Vivo.

Falabella M, Sun L, Barr J, Pena AZ, Kershaw EE, Gingras S, Goncharova EA, Kaufman BA.

G3 (Bethesda). 2017 Oct 5;7(10):3533-3542. doi: 10.1534/g3.117.300123.

11.

Fatty acid oxidation by the osteoblast is required for normal bone acquisition in a sex- and diet-dependent manner.

Kim SP, Li Z, Zoch ML, Frey JL, Bowman CE, Kushwaha P, Ryan KA, Goh BC, Scafidi S, Pickett JE, Faugere MC, Kershaw EE, Thorek DLJ, Clemens TL, Wolfgang MJ, Riddle RC.

JCI Insight. 2017 Aug 17;2(16). pii: 92704. doi: 10.1172/jci.insight.92704. eCollection 2017 Aug 17.

12.

Effects of supervised and unsupervised physical activity programmes for weight loss.

Creasy SA, Rogers RJ, Davis KK, Gibbs BB, Kershaw EE, Jakicic JM.

Obes Sci Pract. 2017 May 5;3(2):143-152. doi: 10.1002/osp4.107. eCollection 2017 Jun.

13.

Differential Impact of Weight Loss on Nonalcoholic Fatty Liver Resolution in a North American Cohort with Obesity.

Rachakonda V, Wills R, DeLany JP, Kershaw EE, Behari J.

Obesity (Silver Spring). 2017 Aug;25(8):1360-1368. doi: 10.1002/oby.21890. Epub 2017 Jun 12.

14.

Kidney triglyceride accumulation in the fasted mouse is dependent upon serum free fatty acids.

Scerbo D, Son NH, Sirwi A, Zeng L, Sas KM, Cifarelli V, Schoiswohl G, Huggins LA, Gumaste N, Hu Y, Pennathur S, Abumrad NA, Kershaw EE, Hussain MM, Susztak K, Goldberg IJ.

J Lipid Res. 2017 Jun;58(6):1132-1142. doi: 10.1194/jlr.M074427. Epub 2017 Apr 12. Erratum in: J Lipid Res. 2017 Sep;58(9):1933.

15.

Autotaxin Is Regulated by Glucose and Insulin in Adipocytes.

D'Souza K, Kane DA, Touaibia M, Kershaw EE, Pulinilkunnil T, Kienesberger PC.

Endocrinology. 2017 Apr 1;158(4):791-803. doi: 10.1210/en.2017-00035.

PMID:
28324037
16.

Liver X receptor α mediates hepatic triglyceride accumulation through upregulation of G0/G1 Switch Gene 2 expression.

Heckmann BL, Zhang X, Saarinen AM, Schoiswohl G, Kershaw EE, Zechner R, Liu J.

JCI Insight. 2017 Feb 23;2(4):e88735. doi: 10.1172/jci.insight.88735.

17.

A thrifty variant in CREBRF strongly influences body mass index in Samoans.

Minster RL, Hawley NL, Su CT, Sun G, Kershaw EE, Cheng H, Buhule OD, Lin J, Reupena MS, Viali S, Tuitele J, Naseri T, Urban Z, Deka R, Weeks DE, McGarvey ST.

Nat Genet. 2016 Sep;48(9):1049-1054. doi: 10.1038/ng.3620. Epub 2016 Jul 25.

18.

Abnormal lipid processing but normal long-term repopulation potential of myc-/- hepatocytes.

Edmunds LR, Otero PA, Sharma L, D'Souza S, Dolezal JM, David S, Lu J, Lamm L, Basantani M, Zhang P, Sipula IJ, Li L, Zeng X, Ding Y, Ding F, Beck ME, Vockley J, Monga SP, Kershaw EE, O'Doherty RM, Kratz LE, Yates NA, Goetzman EP, Scott D, Duncan AW, Prochownik EV.

Oncotarget. 2016 May 24;7(21):30379-95. doi: 10.18632/oncotarget.8856.

19.

Serum Autotaxin/ENPP2 correlates with insulin resistance in older humans with obesity.

Reeves VL, Trybula JS, Wills RC, Goodpaster BH, Dubé JJ, Kienesberger PC, Kershaw EE.

Obesity (Silver Spring). 2015 Dec;23(12):2371-6. doi: 10.1002/oby.21232. Epub 2015 Nov 2.

20.

Three-Dimensional Adipocyte Culture: The Next Frontier for Adipocyte Biology Discovery.

Kokai LE, Marra KG, Kershaw EE.

Endocrinology. 2015 Dec;156(12):4375-6. doi: 10.1210/en.2015-1880. Epub 2015 Oct 22. No abstract available.

21.

Manganese [III] Tetrakis [5,10,15,20]-Benzoic Acid Porphyrin Reduces Adiposity and Improves Insulin Action in Mice with Pre-Existing Obesity.

Brestoff JR, Brodsky T, Sosinsky AZ, McLoughlin R, Stansky E, Fussell L, Sheppard A, DiSanto-Rose M, Kershaw EE, Reynolds TH 4th.

PLoS One. 2015 Sep 23;10(9):e0137388. doi: 10.1371/journal.pone.0137388. eCollection 2015.

22.

Adipose Tissue Lipolysis Promotes Exercise-induced Cardiac Hypertrophy Involving the Lipokine C16:1n7-Palmitoleate.

Foryst-Ludwig A, Kreissl MC, Benz V, Brix S, Smeir E, Ban Z, Januszewicz E, Salatzki J, Grune J, Schwanstecher AK, Blumrich A, Schirbel A, Klopfleisch R, Rothe M, Blume K, Halle M, Wolfarth B, Kershaw EE, Kintscher U.

J Biol Chem. 2015 Sep 25;290(39):23603-15. doi: 10.1074/jbc.M115.645341. Epub 2015 Aug 10.

23.

Impact of Reduced ATGL-Mediated Adipocyte Lipolysis on Obesity-Associated Insulin Resistance and Inflammation in Male Mice.

Schoiswohl G, Stefanovic-Racic M, Menke MN, Wills RC, Surlow BA, Basantani MK, Sitnick MT, Cai L, Yazbeck CF, Stolz DB, Pulinilkunnil T, O'Doherty RM, Kershaw EE.

Endocrinology. 2015 Oct;156(10):3610-24. doi: 10.1210/en.2015-1322. Epub 2015 Jul 21.

24.

Adipose triglyceride lipase acts on neutrophil lipid droplets to regulate substrate availability for lipid mediator synthesis.

Schlager S, Goeritzer M, Jandl K, Frei R, Vujic N, Kolb D, Strohmaier H, Dorow J, Eichmann TO, Rosenberger A, Wölfler A, Lass A, Kershaw EE, Ceglarek U, Dichlberger A, Heinemann A, Kratky D.

J Leukoc Biol. 2015 Nov;98(5):837-50. doi: 10.1189/jlb.3A0515-206R. Epub 2015 Jun 24.

25.

Serum autotaxin is independently associated with hepatic steatosis in women with severe obesity.

Rachakonda VP, Reeves VL, Aljammal J, Wills RC, Trybula JS, DeLany JP, Kienesberger PC, Kershaw EE.

Obesity (Silver Spring). 2015 May;23(5):965-72. doi: 10.1002/oby.20960. Epub 2015 Apr 10.

26.

Adipose triglyceride lipase deletion from adipocytes, but not skeletal myocytes, impairs acute exercise performance in mice.

Dubé JJ, Sitnick MT, Schoiswohl G, Wills RC, Basantani MK, Cai L, Pulinilkunnil T, Kershaw EE.

Am J Physiol Endocrinol Metab. 2015 May 15;308(10):E879-90. doi: 10.1152/ajpendo.00530.2014. Epub 2015 Mar 17.

27.

Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids.

Jaeger D, Schoiswohl G, Hofer P, Schreiber R, Schweiger M, Eichmann TO, Pollak NM, Poecher N, Grabner GF, Zierler KA, Eder S, Kolb D, Radner FP, Preiss-Landl K, Lass A, Zechner R, Kershaw EE, Haemmerle G.

J Hepatol. 2015 Aug;63(2):437-45. doi: 10.1016/j.jhep.2015.02.035. Epub 2015 Feb 27.

28.

Coupling of lipolysis and de novo lipogenesis in brown, beige, and white adipose tissues during chronic β3-adrenergic receptor activation.

Mottillo EP, Balasubramanian P, Lee YH, Weng C, Kershaw EE, Granneman JG.

J Lipid Res. 2014 Nov;55(11):2276-86. doi: 10.1194/jlr.M050005. Epub 2014 Sep 5.

29.

Skeletal muscle triacylglycerol hydrolysis does not influence metabolic complications of obesity.

Sitnick MT, Basantani MK, Cai L, Schoiswohl G, Yazbeck CF, Distefano G, Ritov V, DeLany JP, Schreiber R, Stolz DB, Gardner NP, Kienesberger PC, Pulinilkunnil T, Zechner R, Goodpaster BH, Coen P, Kershaw EE.

Diabetes. 2013 Oct;62(10):3350-61. doi: 10.2337/db13-0500. Epub 2013 Jul 8.

30.

Early structural and metabolic cardiac remodelling in response to inducible adipose triglyceride lipase ablation.

Kienesberger PC, Pulinilkunnil T, Nagendran J, Young ME, Bogner-Strauss JG, Hackl H, Khadour R, Heydari E, Haemmerle G, Zechner R, Kershaw EE, Dyck JR.

Cardiovasc Res. 2013 Aug 1;99(3):442-51. doi: 10.1093/cvr/cvt124. Epub 2013 May 25.

31.

Myocardial adipose triglyceride lipase overexpression protects diabetic mice from the development of lipotoxic cardiomyopathy.

Pulinilkunnil T, Kienesberger PC, Nagendran J, Waller TJ, Young ME, Kershaw EE, Korbutt G, Haemmerle G, Zechner R, Dyck JR.

Diabetes. 2013 May;62(5):1464-77. doi: 10.2337/db12-0927. Epub 2013 Jan 24.

32.

Adipose triglyceride lipase is a TG hydrolase of the small intestine and regulates intestinal PPARα signaling.

Obrowsky S, Chandak PG, Patankar JV, Povoden S, Schlager S, Kershaw EE, Bogner-Strauss JG, Hoefler G, Levak-Frank S, Kratky D.

J Lipid Res. 2013 Feb;54(2):425-35. doi: 10.1194/jlr.M031716. Epub 2012 Dec 6.

33.

Regulation of insulin and leptin signaling by muscle suppressor of cytokine signaling 3 (SOCS3).

Yang Z, Hulver M, McMillan RP, Cai L, Kershaw EE, Yu L, Xue B, Shi H.

PLoS One. 2012;7(10):e47493. doi: 10.1371/journal.pone.0047493. Epub 2012 Oct 24.

34.

Adiponutrin functions as a nutritionally regulated lysophosphatidic acid acyltransferase.

Kumari M, Schoiswohl G, Chitraju C, Paar M, Cornaciu I, Rangrez AY, Wongsiriroj N, Nagy HM, Ivanova PT, Scott SA, Knittelfelder O, Rechberger GN, Birner-Gruenberger R, Eder S, Brown HA, Haemmerle G, Oberer M, Lass A, Kershaw EE, Zimmermann R, Zechner R.

Cell Metab. 2012 May 2;15(5):691-702. doi: 10.1016/j.cmet.2012.04.008.

35.

Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction.

Kienesberger PC, Pulinilkunnil T, Sung MM, Nagendran J, Haemmerle G, Kershaw EE, Young ME, Light PE, Oudit GY, Zechner R, Dyck JR.

Mol Cell Biol. 2012 Feb;32(4):740-50. doi: 10.1128/MCB.06470-11. Epub 2011 Dec 12.

36.

ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1.

Haemmerle G, Moustafa T, Woelkart G, Büttner S, Schmidt A, van de Weijer T, Hesselink M, Jaeger D, Kienesberger PC, Zierler K, Schreiber R, Eichmann T, Kolb D, Kotzbeck P, Schweiger M, Kumari M, Eder S, Schoiswohl G, Wongsiriroj N, Pollak NM, Radner FP, Preiss-Landl K, Kolbe T, Rülicke T, Pieske B, Trauner M, Lass A, Zimmermann R, Hoefler G, Cinti S, Kershaw EE, Schrauwen P, Madeo F, Mayer B, Zechner R.

Nat Med. 2011 Aug 21;17(9):1076-85. doi: 10.1038/nm.2439.

37.

Transcriptional control of adipose lipid handling by IRF4.

Eguchi J, Wang X, Yu S, Kershaw EE, Chiu PC, Dushay J, Estall JL, Klein U, Maratos-Flier E, Rosen ED.

Cell Metab. 2011 Mar 2;13(3):249-59. doi: 10.1016/j.cmet.2011.02.005.

38.

Pnpla3/Adiponutrin deficiency in mice does not contribute to fatty liver disease or metabolic syndrome.

Basantani MK, Sitnick MT, Cai L, Brenner DS, Gardner NP, Li JZ, Schoiswohl G, Yang K, Kumari M, Gross RW, Zechner R, Kershaw EE.

J Lipid Res. 2011 Feb;52(2):318-29. doi: 10.1194/jlr.M011205. Epub 2010 Nov 9.

39.

Adipose triglyceride lipase deficiency causes tissue-specific changes in insulin signaling.

Kienesberger PC, Lee D, Pulinilkunnil T, Brenner DS, Cai L, Magnes C, Koefeler HC, Streith IE, Rechberger GN, Haemmerle G, Flier JS, Zechner R, Kim YB, Kershaw EE.

J Biol Chem. 2009 Oct 30;284(44):30218-29. doi: 10.1074/jbc.M109.047787. Epub 2009 Aug 31.

40.

Protein-tyrosine phosphatase 1B expression is induced by inflammation in vivo.

Zabolotny JM, Kim YB, Welsh LA, Kershaw EE, Neel BG, Kahn BB.

J Biol Chem. 2008 May 23;283(21):14230-41. doi: 10.1074/jbc.M800061200. Epub 2008 Feb 14.

41.

PPARgamma regulates adipose triglyceride lipase in adipocytes in vitro and in vivo.

Kershaw EE, Schupp M, Guan HP, Gardner NP, Lazar MA, Flier JS.

Am J Physiol Endocrinol Metab. 2007 Dec;293(6):E1736-45. Epub 2007 Sep 11.

42.

Adipose triglyceride lipase: function, regulation by insulin, and comparison with adiponutrin.

Kershaw EE, Hamm JK, Verhagen LA, Peroni O, Katic M, Flier JS.

Diabetes. 2006 Jan;55(1):148-57.

43.

Adipocyte-specific glucocorticoid inactivation protects against diet-induced obesity.

Kershaw EE, Morton NM, Dhillon H, Ramage L, Seckl JR, Flier JS.

Diabetes. 2005 Apr;54(4):1023-31.

44.

Adipose tissue as an endocrine organ.

Kershaw EE, Flier JS.

J Clin Endocrinol Metab. 2004 Jun;89(6):2548-56. Review.

PMID:
15181022
45.

The rat corpulent (cp) mutation maps to the same interval on (Pgm1-Glut1) rat chromosome 5 as the fatty (fa) mutation.

Kahle EB, Butz KG, Chua SC, Kershaw EE, Leibel RL, Fenger TW, Hansen CT, Michaelis OE.

Obes Res. 1997 Mar;5(2):142-5.

46.

Phenotype of fatty due to Gln269Pro mutation in the leptin receptor (Lepr).

Chua SC Jr, White DW, Wu-Peng XS, Liu SM, Okada N, Kershaw EE, Chung WK, Power-Kehoe L, Chua M, Tartaglia LA, Leibel RL.

Diabetes. 1996 Aug;45(8):1141-3.

PMID:
8690163
47.

Perinatal energy stores and excessive fat deposition in genetically obese (fa/fa) rats.

Meierfrankenfeld B, Abelenda M, Jauker H, Klingenspor M, Kershaw EE, Chua SC Jr, Leibel RL, Schmidt I.

Am J Physiol. 1996 Apr;270(4 Pt 1):E700-8.

PMID:
8928778
48.

Molecular mapping of SSRs for Pgm1 and C8b in the vicinity of the rat fatty locus.

Kershaw EE, Chua SC, Williams JA, Murphy EM, Leibel RL.

Genomics. 1995 May 1;27(1):149-54.

PMID:
7665162
49.

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