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Items: 1 to 50 of 53

1.

Genetic Similarity of Gonococcal Homologs to Meningococcal Outer Membrane Proteins of Serogroup B Vaccine.

Marjuki H, Topaz N, Joseph SJ, Gernert KM, Kersh EN; Antimicrobial-Resistant Neisseria gonorrhoeae Working Group, Wang X.

MBio. 2019 Sep 10;10(5). pii: e01668-19. doi: 10.1128/mBio.01668-19.

2.

Chronic immune barrier dysregulation among women with a history of violence victimization.

Swaims-Kohlmeier A, Haddad LB, Li ZT, Brookmeyer KA, Baker JM, Widom CS, Lamousin JC, Chi KH, Chen CY, Kersh EN, Johnson JA, Herbst-Kralovetz MM, Hogben M, Ofotokun I, Kohlmeier JE.

JCI Insight. 2019 May 16;4(10). pii: 126097. doi: 10.1172/jci.insight.126097. eCollection 2019 May 16.

3.

Rationale for a Neisseria gonorrhoeae Susceptible Only Interpretive Breakpoint for Azithromycin.

Kersh EN, Allen V, Ransom E, Schmerer M, St Cyr S, Workowski K, Weinstock H, Patel J, Ferraro MJ.

Clin Infect Dis. 2019 Apr 9. pii: ciz292. doi: 10.1093/cid/ciz292. [Epub ahead of print]

PMID:
30963175
4.

Emergence of Neisseria gonorrhoeae Strains Harboring a Novel Combination of Azithromycin-Attenuating Mutations.

Pham CD, Sharpe S, Schlanger K, St Cyr S, Holderman J, Steece R, Soge OO, Masinde G, Arno J, Schmerer M, Kersh EN; SURRG Working Group.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02313-18. doi: 10.1128/AAC.02313-18. Print 2019 Apr.

PMID:
30917979
5.

Evidence of Recent Genomic Evolution in Gonococcal Strains With Decreased Susceptibility to Cephalosporins or Azithromycin in the United States, 2014-2016.

Thomas JC, Seby S, Abrams AJ, Cartee J, Lucking S, Vidyaprakash E, Schmerer M, Pham CD, Hong J, Torrone E, Cyr SS, Shafer WM, Bernstein K, Kersh EN, Gernert KM; Antimicrobial-Resistant Neisseria gonorrhoeae Working Group .

J Infect Dis. 2019 Jun 19;220(2):294-305. doi: 10.1093/infdis/jiz079.

PMID:
30788502
6.

In vitro activity of EDTA and TOL-463 against Neisseria gonorrhoeae.

Nash EE, Henning TC, Pham CD, Pettus K, Sharpe S, Kersh EN.

Diagn Microbiol Infect Dis. 2019 Apr;93(4):369-371. doi: 10.1016/j.diagmicrobio.2018.10.021. Epub 2018 Nov 10.

PMID:
30552033
7.

Mechanistic Basis for Decreased Antimicrobial Susceptibility in a Clinical Isolate of Neisseria gonorrhoeae Possessing a Mosaic-Like mtr Efflux Pump Locus.

Rouquette-Loughlin CE, Reimche JL, Balthazar JT, Dhulipala V, Gernert KM, Kersh EN, Pham CD, Pettus K, Abrams AJ, Trees DL, St Cyr S, Shafer WM.

MBio. 2018 Nov 27;9(6). pii: e02281-18. doi: 10.1128/mBio.02281-18.

8.

Progestin-based contraception regimens modulate expression of putative HIV risk factors in the vaginal epithelium of pig-tailed Macaques.

Bosinger SE, Tharp GK, Patel NB, Zhao C, Payne TL, Dietz Ostergaard S, Butler K, Ellis S, Johnson RL, Kersh EN, McNicholl JM, Vishwanathan SA.

Am J Reprod Immunol. 2018 Oct;80(4):e13029. doi: 10.1111/aji.13029. Epub 2018 Aug 3.

PMID:
30076667
9.

Laboratory Evaluation of a Commercially Available Rapid Syphilis Test.

Pereira LE, McCormick J, Dorji T, Kang J, Sun Y, Shukla M, Hopkins A, Deutsch J, Kersh EN, Bernstein K, Fakile YF.

J Clin Microbiol. 2018 Sep 25;56(10). pii: e00832-18. doi: 10.1128/JCM.00832-18. Print 2018 Oct.

10.

Biomedical Research Priorities for Modern Syphilis Clinical Management, Diagnosis, and Vaccines: Overview and Commentary for Unit 1.

Kersh EN, Lukehart SA.

Sex Transm Dis. 2018 Sep;45(9S Suppl 1):S7-S9. doi: 10.1097/OLQ.0000000000000830.

11.

Considering the Potential Application of Whole Genome Sequencing to Gonorrhea Prevention and Control.

Kirkcaldy RD, Town K, Gernert KM, Bowen VB, Torrone EA, Kersh EN, Bernstein KT.

Sex Transm Dis. 2018 Jun;45(6):e29-e32. doi: 10.1097/OLQ.0000000000000813. No abstract available.

12.

A Nonhuman Primate Model for Rectally Transmitted Syphilis.

Tansey C, Zhao C, Hopkins A, Ritter JM, Fakile YF, Pillay A, Katz SS, Pereira L, Mitchell J, Deyounks F, Kersh EN, McNicholl JM, Vishwanathan SA.

J Infect Dis. 2018 Mar 13;217(7):1139-1144. doi: 10.1093/infdis/jix669.

13.

Laboratory Processes for Confirmation of Lymphogranuloma Venereum Infection During a 2015 Investigation of a Cluster of Cases in the United States.

Kersh EN, Pillay A, de Voux A, Chen C.

Sex Transm Dis. 2017 Nov;44(11):691-694. doi: 10.1097/OLQ.0000000000000667.

14.

A Macaque Model for Rectal Lymphogranuloma Venereum and Non-Lymphogranuloma Venereum Chlamydia trachomatis: Impact on Rectal Simian/Human Immunodeficiency Virus Acquisition.

Vishwanathan SA, Aubert RD, Morris MR, Zhao C, Philips C, Khalil GM, Deyounks F, Kelley K, Ritter JM, Chen CY, Kersh EN, McNicholl JM.

Sex Transm Dis. 2017 Sep;44(9):551-556. doi: 10.1097/OLQ.0000000000000644.

15.

Cluster of Neisseria gonorrhoeae Isolates With High-level Azithromycin Resistance and Decreased Ceftriaxone Susceptibility, Hawaii, 2016.

Katz AR, Komeya AY, Kirkcaldy RD, Whelen AC, Soge OO, Papp JR, Kersh EN, Wasserman GM, O'Connor NP, O'Brien PS, Sato DT, Maningas EV, Kunimoto GY, Tomas JE.

Clin Infect Dis. 2017 Sep 15;65(6):918-923. doi: 10.1093/cid/cix485.

16.

Development of a rectal sexually transmitted infection (STI) Model in Rhesus macaques using Chlamydia trachomatis serovars E and L2.

Henning TR, Morris M, Ellis S, Kelley K, Phillips C, Ritter J, Jones T, Nachamkin E, Chen CY, Hong J, Kang J, Patton D, McNicholl J, Papp J, Kersh EN.

J Med Primatol. 2017 Oct;46(5):218-227. doi: 10.1111/jmp.12272. Epub 2017 May 10.

PMID:
28488731
17.

Azithromycin Resistance and Decreased Ceftriaxone Susceptibility in Neisseria gonorrhoeae, Hawaii, USA.

Papp JR, Abrams AJ, Nash E, Katz AR, Kirkcaldy RD, O'Connor NP, O'Brien PS, Harauchi DH, Maningas EV, Soge OO, Kersh EN, Komeya A, Tomas JE, Wasserman GM, Kunimoto GY, Trees DL, Whelen AC.

Emerg Infect Dis. 2017 May;23(5):830-832. doi: 10.3201/eid2305.170088.

18.

Neisseria gonorrhoeae Sequence Typing for Antimicrobial Resistance, a Novel Antimicrobial Resistance Multilocus Typing Scheme for Tracking Global Dissemination of N. gonorrhoeae Strains.

Demczuk W, Sidhu S, Unemo M, Whiley DM, Allen VG, Dillon JR, Cole M, Seah C, Trembizki E, Trees DL, Kersh EN, Abrams AJ, de Vries HJC, van Dam AP, Medina I, Bharat A, Mulvey MR, Van Domselaar G, Martin I.

J Clin Microbiol. 2017 May;55(5):1454-1468. doi: 10.1128/JCM.00100-17. Epub 2017 Feb 22.

19.

Increases in Endogenous or Exogenous Progestins Promote Virus-Target Cell Interactions within the Non-human Primate Female Reproductive Tract.

Carias AM, Allen SA, Fought AJ, Kotnik Halavaty K, Anderson MR, Jimenez ML, McRaven MD, Gioia CJ, Henning TR, Kersh EN, Smith JM, Pereira LE, Butler K, McNicholl SJ, Hendry RM, Kiser PF, Veazey RS, Hope TJ.

PLoS Pathog. 2016 Sep 22;12(9):e1005885. doi: 10.1371/journal.ppat.1005885. eCollection 2016 Sep.

20.

Notes from the Field: Cluster of Lymphogranuloma Venereum Cases Among Men Who Have Sex with Men - Michigan, August 2015-April 2016.

de Voux A, Kent JB, Macomber K, Krzanowski K, Jackson D, Starr T, Johnson S, Richmond D, Crane LR, Cohn J, Finch C, McFadden J, Pillay A, Chen C, Anderson L, Kersh EN.

MMWR Morb Mortal Wkly Rep. 2016 Sep 2;65(34):920-1. doi: 10.15585/mmwr.mm6534a6.

21.

A Depot Medroxyprogesterone Acetate Dose That Models Human Use and Its Effect on Vaginal SHIV Acquisition Risk.

Butler K, Ritter JM, Ellis S, Morris MR, Hanson DL, McNicholl JM, Kersh EN.

J Acquir Immune Defic Syndr. 2016 Aug 1;72(4):363-71. doi: 10.1097/QAI.0000000000000975.

22.

Combination Emtricitabine and Tenofovir Disoproxil Fumarate Prevents Vaginal Simian/Human Immunodeficiency Virus Infection in Macaques Harboring Chlamydia trachomatis and Trichomonas vaginalis.

Radzio J, Henning T, Jenkins L, Ellis S, Farshy C, Phillips C, Holder A, Kuklenyik S, Dinh C, Hanson D, McNicholl J, Heneine W, Papp J, Kersh EN, García-Lerma JG.

J Infect Dis. 2016 May 15;213(10):1541-5. doi: 10.1093/infdis/jiw002. Epub 2016 Jan 6.

23.

Relationship of Estimated SHIV Acquisition Time Points During the Menstrual Cycle and Thinning of Vaginal Epithelial Layers in Pigtail Macaques.

Kersh EN, Ritter J, Butler K, Ostergaard SD, Hanson D, Ellis S, Zaki S, McNicholl JM.

Sex Transm Dis. 2015 Dec;42(12):694-701. doi: 10.1097/OLQ.0000000000000367.

24.

Analysis of putative mucosal SHIV susceptibility factors during repeated DMPA treatments in pigtail macaques.

Butler K, Ritter J, Ellis S, Henning TR, Montague J, Zaki S, Garber D, McNicholl JM, Kersh EN.

J Med Primatol. 2015 Oct;44(5):286-95. doi: 10.1111/jmp.12188. Epub 2015 Aug 4.

PMID:
26238265
25.

Short Communication: Practical Experience with Analysis and Design of Repeat Low-Dose SHIVSF162P3 Exposure Studies in Female Pigtail Macaques with Varying Susceptibility During Menstrual Cycling.

Kersh EN, Henning TR, Dobard C, Heneine W, McNicholl JM.

AIDS Res Hum Retroviruses. 2015 Nov;31(11):1166-9. doi: 10.1089/AID.2014.0373. Epub 2015 Aug 6.

26.

Cataloguing of Potential HIV Susceptibility Factors during the Menstrual Cycle of Pig-Tailed Macaques by Using a Systems Biology Approach.

Vishwanathan SA, Burgener A, Bosinger SE, Tharp GK, Guenthner PC, Patel NB, Birse K, Hanson DL, Westmacott GR, Henning TR, Radzio J, Garcia-Lerma JG, Ball TB, McNicholl JM, Kersh EN.

J Virol. 2015 Sep;89(18):9167-77. doi: 10.1128/JVI.00263-15. Epub 2015 Jun 24.

27.

Macaque models of enhanced susceptibility to HIV.

Henning TR, McNicholl JM, Vishwanathan SA, Kersh EN.

Virol J. 2015 Jun 14;12:90. doi: 10.1186/s12985-015-0320-6. Review.

28.

Relationship of menstrual cycle and vaginal infection in female rhesus macaques challenged with repeated, low doses of SIVmac251.

Morris MR, Byrareddy SN, Villinger F, Henning TC, Butler K, Ansari AA, McNicholl JM, Kersh EN.

J Med Primatol. 2015 Oct;44(5):301-5. doi: 10.1111/jmp.12177. Epub 2015 Jun 5.

29.

Repeated Vaginal SHIV Challenges in Macaques Receiving Oral or Topical Preexposure Prophylaxis Induce Virus-Specific T-Cell Responses.

Tsegaye TS, Butler K, Luo W, Radzio J, Srinivasan P, Sharma S, Aubert RD, Hanson DL, Dobard C, Garcia-Lerma JG, Heneine W, McNicholl JM, Kersh EN.

J Acquir Immune Defic Syndr. 2015 Aug 1;69(4):385-94. doi: 10.1097/QAI.0000000000000642.

30.

Rectal application of a highly osmolar personal lubricant in a macaque model induces acute cytotoxicity but does not increase risk of SHIV infection.

Vishwanathan SA, Morris MR, Wolitski RJ, Luo W, Rose CE, Blau DM, Tsegaye T, Zaki SR, Garber DA, Jenkins LT, Henning TC, Patton DL, Hendry RM, McNicholl JM, Kersh EN.

PLoS One. 2015 Apr 8;10(4):e0120021. doi: 10.1371/journal.pone.0120021. eCollection 2015.

31.

A combined oral contraceptive affects mucosal SHIV susceptibility factors in a pigtail macaque (Macaca nemestrina) model.

Dietz Ostergaard S, Butler K, Ritter JM, Johnson R, Sanders J, Powell N, Lathrop G, Zaki SR, McNicholl JM, Kersh EN.

J Med Primatol. 2015 Apr;44(2):97-107. doi: 10.1111/jmp.12157. Epub 2014 Dec 23.

32.

Targeting α4β7 integrin reduces mucosal transmission of simian immunodeficiency virus and protects gut-associated lymphoid tissue from infection.

Byrareddy SN, Kallam B, Arthos J, Cicala C, Nawaz F, Hiatt J, Kersh EN, McNicholl JM, Hanson D, Reimann KA, Brameier M, Walter L, Rogers K, Mayne AE, Dunbar P, Villinger T, Little D, Parslow TG, Santangelo PJ, Villinger F, Fauci AS, Ansari AA.

Nat Med. 2014 Dec;20(12):1397-400. doi: 10.1038/nm.3715. Epub 2014 Nov 24.

33.

Preclinical evaluation of the immunomodulatory lymphocyte trafficking drug FTY720 for HIV prevention in the female genital mucosa of macaques.

Morris M, Aubert RD, Butler K, Henning T, Mitchell J, Jenkins L, Garber D, McNicholl J, Kersh EN.

J Med Primatol. 2014 Oct;43(5):370-3.

34.

Short communication: Viremic control is independent of repeated low-dose SHIVSF162p3 exposures.

Henning TR, Hanson D, Vishwanathan SA, Butler K, Dobard C, Garcia-Lerma G, Radzio J, Smith J, McNicholl JM, Kersh EN.

AIDS Res Hum Retroviruses. 2014 Nov;30(11):1125-9. doi: 10.1089/aid.2014.0238. Epub 2014 Oct 14.

35.

SHIV susceptibility changes during the menstrual cycle of pigtail macaques.

Kersh EN, Henning T, Vishwanathan SA, Morris M, Butler K, Adams DR, Guenthner P, Srinivasan P, Smith J, Radzio J, Garcia-Lerma JG, Dobard C, Heneine W, McNicholl J.

J Med Primatol. 2014 Oct;43(5):310-6. doi: 10.1111/jmp.12124. Epub 2014 Apr 29.

36.

Non-human primate models of hormonal contraception and HIV.

McNicholl JM, Henning TC, Vishwanathan SA, Kersh EN.

Am J Reprod Immunol. 2014 Jun;71(6):513-22. doi: 10.1111/aji.12246. Epub 2014 Apr 10.

PMID:
24716832
37.

Evaluation of pigtail macaques as a model for the effects of copper intrauterine devices on HIV infection.

Engel RM, Morris M, Henning T, Ritter JM, Jones TL, Dietz S, Ayers J, Vishwanathan SA, Jenkins L, Zaki S, Wildemeersch D, Garber D, Powell N, Hendry RM, McNicholl J, Kersh EN.

J Med Primatol. 2014 Oct;43(5):349-59. doi: 10.1111/jmp.12096. Epub 2013 Dec 27.

38.

Susceptibility to repeated, low-dose, rectal SHIVSF162P3 challenge is independent of TRIM5 genotype in rhesus macaques.

Butler K, Morgan JS, Hanson DL, Adams D, Garcia-Lerma JG, Heneine W, Ellenberger D, Hendry RM, McNicholl J, Johnson WE, Kersh EN.

AIDS Res Hum Retroviruses. 2013 Jul;29(7):1091-4. doi: 10.1089/AID.2012.0383. Epub 2013 Mar 29.

39.

Reduced inflammation and CD4 loss in acute SHIV infection during oral pre-exposure prophylaxis.

Kersh EN, Luo W, Zheng Q, Adams DR, Hanson D, Youngpairoj AS, Cong ME, Butler K, Hendry RM, McNicholl JM, Heneine W, Garcia-Lerma JG.

J Infect Dis. 2012 Sep 1;206(5):770-9. doi: 10.1093/infdis/jis422. Epub 2012 Jun 27.

40.

High susceptibility to repeated, low-dose, vaginal SHIV exposure late in the luteal phase of the menstrual cycle of pigtail macaques.

Vishwanathan SA, Guenthner PC, Lin CY, Dobard C, Sharma S, Adams DR, Otten RA, Heneine W, Hendry RM, McNicholl JM, Kersh EN.

J Acquir Immune Defic Syndr. 2011 Aug 1;57(4):261-4. doi: 10.1097/QAI.0b013e318220ebd3.

PMID:
21546848
41.

T cell chemo-vaccination effects after repeated mucosal SHIV exposures and oral pre-exposure prophylaxis.

Kersh EN, Adams DR, Youngpairoj AS, Luo W, Zheng Q, Cong ME, Aung W, Mitchell J, Otten R, Hendry RM, Heneine W, McNicholl J, Garcia-Lerma JG.

PLoS One. 2011 Apr 26;6(4):e19295. doi: 10.1371/journal.pone.0019295.

42.

Resistance to Simian HIV infection is associated with high plasma interleukin-8, RANTES and Eotaxin in a macaque model of repeated virus challenges.

Promadej-Lanier N, Hanson DL, Srinivasan P, Luo W, Adams DR, Guenthner PC, Butera S, Otten RA, Kersh EN.

J Acquir Immune Defic Syndr. 2010 Apr;53(5):574-81. doi: 10.1097/QAI.0b013e3181d3521f.

PMID:
20164782
43.

Repeated rectal SHIVSF162P3 exposures do not consistently induce sustained T cell responses prior to systemic infection in the repeat-low dose preclinical macaque model.

Kersh EN, Luo W, Adams DR, Srinivasan P, Smith JM, Promadej-Lanier N, Ellenberger D, Garcia-Lerma JG, Butera S, Otten R.

AIDS Res Hum Retroviruses. 2009 Sep;25(9):905-17. doi: 10.1089/aid.2008.0287.

PMID:
19689194
44.

Evaluation of the lymphocyte trafficking drug FTY720 in SHIVSF162P3-infected rhesus macaques.

Kersh EN, Luo W, Adams DR, Mitchell J, Garcia-Lerma JG, Butera S, Folks T, Otten R.

J Antimicrob Chemother. 2009 Apr;63(4):758-62. doi: 10.1093/jac/dkp008. Epub 2009 Feb 13.

PMID:
19218272
45.

Short communication: no evidence of occult SHIV infection as demonstrated by CD8+ cell depletion after chemoprophylaxis-induced protection from mucosal infection in rhesus macaques.

Kersh EN, Luo W, Adams DR, Mitchell J, Garcia-Lerma JG, Heneine W, Folks TM, Butera S, Otten RA.

AIDS Res Hum Retroviruses. 2008 Apr;24(4):543-6. doi: 10.1089/aid.2007.0222.

PMID:
18370590
46.
47.

Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells.

Kersh EN, Fitzpatrick DR, Murali-Krishna K, Shires J, Speck SH, Boss JM, Ahmed R.

J Immunol. 2006 Apr 1;176(7):4083-93.

48.

TCR signal transduction in antigen-specific memory CD8 T cells.

Kersh EN, Kaech SM, Onami TM, Moran M, Wherry EJ, Miceli MC, Ahmed R.

J Immunol. 2003 Jun 1;170(11):5455-63.

PMID:
12759421
49.

SAP is required for generating long-term humoral immunity.

Crotty S, Kersh EN, Cannons J, Schwartzberg PL, Ahmed R.

Nature. 2003 Jan 16;421(6920):282-7.

PMID:
12529646
50.

Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP.

Czar MJ, Kersh EN, Mijares LA, Lanier G, Lewis J, Yap G, Chen A, Sher A, Duckett CS, Ahmed R, Schwartzberg PL.

Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7449-54. Epub 2001 Jun 12.

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