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Items: 1 to 50 of 104

1.

Corticospinal circuit remodeling after central nervous system injury is dependent on neuronal activity.

Bradley PM, Denecke CK, Aljovic A, Schmalz A, Kerschensteiner M, Bareyre FM.

J Exp Med. 2019 Aug 7. pii: jem.20181406. doi: 10.1084/jem.20181406. [Epub ahead of print]

PMID:
31391209
2.

[Diagnostics and treatment of tuberculosis under immunotherapy for multiple sclerosis : Current status and recommendations in Germany].

Bittner S, Engel S, Lange C, Weber MS, Haghikia A, Luessi F, Korn T, Klotz L, Bayas A, Paul F, Heesen C, Stangel M, Wildemann B, Bergh FT, Tackenberg B, Trebst C, Warnke C, Linker R, Kerschensteiner M, Zettl U, Tumani H, Brück W, Meuth SG, Kümpfel T, Hemmer B, Wiendl H, Gold R, Zipp F.

Nervenarzt. 2019 Jul 11. doi: 10.1007/s00115-019-0760-0. [Epub ahead of print] Review. German.

PMID:
31297574
3.

Imaging the execution phase of neuroinflammatory disease models.

Schumacher AM, Misgeld T, Kerschensteiner M, Snaidero N.

Exp Neurol. 2019 Oct;320:112968. doi: 10.1016/j.expneurol.2019.112968. Epub 2019 May 29. Review.

PMID:
31152743
4.

Calcium Influx through Plasma-Membrane Nanoruptures Drives Axon Degeneration in a Model of Multiple Sclerosis.

Witte ME, Schumacher AM, Mahler CF, Bewersdorf JP, Lehmitz J, Scheiter A, Sánchez P, Williams PR, Griesbeck O, Naumann R, Misgeld T, Kerschensteiner M.

Neuron. 2019 Feb 20;101(4):615-624.e5. doi: 10.1016/j.neuron.2018.12.023. Epub 2019 Jan 24.

5.

Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation.

Jordão MJC, Sankowski R, Brendecke SM, Sagar, Locatelli G, Tai YH, Tay TL, Schramm E, Armbruster S, Hagemeyer N, Groß O, Mai D, Çiçek Ö, Falk T, Kerschensteiner M, Grün D, Prinz M.

Science. 2019 Jan 25;363(6425). pii: eaat7554. doi: 10.1126/science.aat7554.

PMID:
30679343
6.

Temporal evolution of acute multiple sclerosis lesions on serial sodium (23Na) MRI.

Eisele P, Konstandin S, Szabo K, Ebert A, Roßmanith C, Paschke N, Kerschensteiner M, Platten M, Schoenberg SO, Schad LR, Gass A.

Mult Scler Relat Disord. 2019 Apr;29:48-54. doi: 10.1016/j.msard.2019.01.027. Epub 2019 Jan 17.

PMID:
30669020
7.

Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections.

Cai R, Pan C, Ghasemigharagoz A, Todorov MI, Förstera B, Zhao S, Bhatia HS, Parra-Damas A, Mrowka L, Theodorou D, Rempfler M, Xavier ALR, Kress BT, Benakis C, Steinke H, Liebscher S, Bechmann I, Liesz A, Menze B, Kerschensteiner M, Nedergaard M, Ertürk A.

Nat Neurosci. 2019 Feb;22(2):317-327. doi: 10.1038/s41593-018-0301-3. Epub 2018 Dec 31.

8.

Imaging microglial activation in tacrolimus-associated CNS vasculitis with translocator protein PET.

Mahler C, Unterrainer M, Muth C, Egensperger R, Vomacka L, Lindner S, Ertl-Wagner B, Patzig M, Bartenstein P, Albert N, Kerschensteiner M, Kümpfel T.

Neurology. 2018 Nov 13;91(20):936-937. doi: 10.1212/WNL.0000000000006516. No abstract available.

PMID:
30420457
9.

Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model.

Locatelli G, Theodorou D, Kendirli A, Jordão MJC, Staszewski O, Phulphagar K, Cantuti-Castelvetri L, Dagkalis A, Bessis A, Simons M, Meissner F, Prinz M, Kerschensteiner M.

Nat Neurosci. 2018 Sep;21(9):1196-1208. doi: 10.1038/s41593-018-0212-3. Epub 2018 Aug 20.

PMID:
30127427
10.

TSPO PET with [18F]GE-180 sensitively detects focal neuroinflammation in patients with relapsing-remitting multiple sclerosis.

Unterrainer M, Mahler C, Vomacka L, Lindner S, Havla J, Brendel M, Böning G, Ertl-Wagner B, Kümpfel T, Milenkovic VM, Rupprecht R, Kerschensteiner M, Bartenstein P, Albert NL.

Eur J Nucl Med Mol Imaging. 2018 Jul;45(8):1423-1431. doi: 10.1007/s00259-018-3974-7. Epub 2018 Mar 9.

PMID:
29523925
11.

TSPO imaging using the novel PET ligand [18F]GE-180: quantification approaches in patients with multiple sclerosis.

Vomacka L, Albert NL, Lindner S, Unterrainer M, Mahler C, Brendel M, Ermoschkin L, Gosewisch A, Brunegraf A, Buckley C, Kümpfel T, Rupprecht R, Ziegler S, Kerschensteiner M, Bartenstein P, Böning G.

EJNMMI Res. 2017 Oct 26;7(1):89. doi: 10.1186/s13550-017-0340-x.

12.

Neuroplasticity and its relevance for multiple sclerosis.

Kerschensteiner M.

Neurodegener Dis Manag. 2017 Nov;7(6s):31-33. doi: 10.2217/nmt-2017-0039. No abstract available.

PMID:
29143580
13.

TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.

Mazaheri F, Snaidero N, Kleinberger G, Madore C, Daria A, Werner G, Krasemann S, Capell A, Trümbach D, Wurst W, Brunner B, Bultmann S, Tahirovic S, Kerschensteiner M, Misgeld T, Butovsky O, Haass C.

EMBO Rep. 2017 Jul;18(7):1186-1198. doi: 10.15252/embr.201743922. Epub 2017 May 8.

14.

Myelinosome formation represents an early stage of oligodendrocyte damage in multiple sclerosis and its animal model.

Romanelli E, Merkler D, Mezydlo A, Weil MT, Weber MS, Nikić I, Potz S, Meinl E, Matznick FE, Kreutzfeldt M, Ghanem A, Conzelmann KK, Metz I, Brück W, Routh M, Simons M, Bishop D, Misgeld T, Kerschensteiner M.

Nat Commun. 2016 Nov 16;7:13275. doi: 10.1038/ncomms13275.

15.

Antiglutamatergic therapy for multiple sclerosis?

Hohlfeld R, Kerschensteiner M.

Lancet Neurol. 2016 Sep;15(10):1003-4. doi: 10.1016/S1474-4422(16)30163-6. Epub 2016 Aug 8. No abstract available.

PMID:
27571145
16.

Loss of Myelin Basic Protein Function Triggers Myelin Breakdown in Models of Demyelinating Diseases.

Weil MT, Möbius W, Winkler A, Ruhwedel T, Wrzos C, Romanelli E, Bennett JL, Enz L, Goebels N, Nave KA, Kerschensteiner M, Schaeren-Wiemers N, Stadelmann C, Simons M.

Cell Rep. 2016 Jul 12;16(2):314-322. doi: 10.1016/j.celrep.2016.06.008. Epub 2016 Jun 23.

17.

Origin, fate and dynamics of macrophages at central nervous system interfaces.

Goldmann T, Wieghofer P, Jordão MJ, Prutek F, Hagemeyer N, Frenzel K, Amann L, Staszewski O, Kierdorf K, Krueger M, Locatelli G, Hochgerner H, Zeiser R, Epelman S, Geissmann F, Priller J, Rossi FM, Bechmann I, Kerschensteiner M, Linnarsson S, Jung S, Prinz M.

Nat Immunol. 2016 Jul;17(7):797-805. doi: 10.1038/ni.3423. Epub 2016 May 2.

18.

Mouse redox histology using genetically encoded probes.

Fujikawa Y, Roma LP, Sobotta MC, Rose AJ, Diaz MB, Locatelli G, Breckwoldt MO, Misgeld T, Kerschensteiner M, Herzig S, Müller-Decker K, Dick TP.

Sci Signal. 2016 Mar 15;9(419):rs1. doi: 10.1126/scisignal.aad3895.

PMID:
26980443
19.

Reconstruction of single cortical projection neurons reveals primary spine loss in multiple sclerosis.

Jürgens T, Jafari M, Kreutzfeldt M, Bahn E, Brück W, Kerschensteiner M, Merkler D.

Brain. 2016 Jan;139(Pt 1):39-46. doi: 10.1093/brain/awv353. Epub 2015 Dec 14.

PMID:
26667278
20.

Astrocyte Depletion Impairs Redox Homeostasis and Triggers Neuronal Loss in the Adult CNS.

Schreiner B, Romanelli E, Liberski P, Ingold-Heppner B, Sobottka-Brillout B, Hartwig T, Chandrasekar V, Johannssen H, Zeilhofer HU, Aguzzi A, Heppner F, Kerschensteiner M, Becher B.

Cell Rep. 2015 Sep 1;12(9):1377-84. doi: 10.1016/j.celrep.2015.07.051. Epub 2015 Aug 20.

21.

Role of the innate and adaptive immune responses in the course of multiple sclerosis.

Hemmer B, Kerschensteiner M, Korn T.

Lancet Neurol. 2015 Apr;14(4):406-19. doi: 10.1016/S1474-4422(14)70305-9. Review.

PMID:
25792099
22.

FGF22 signaling regulates synapse formation during post-injury remodeling of the spinal cord.

Jacobi A, Loy K, Schmalz AM, Hellsten M, Umemori H, Kerschensteiner M, Bareyre FM.

EMBO J. 2015 May 5;34(9):1231-43. doi: 10.15252/embj.201490578. Epub 2015 Mar 12.

23.

Redox imaging using genetically encoded redox indicators in zebrafish and mice.

Breckwoldt MO, Wittmann C, Misgeld T, Kerschensteiner M, Grabher C.

Biol Chem. 2015 May;396(5):511-22. doi: 10.1515/hsz-2014-0294. Review.

PMID:
25720068
24.

A recoverable state of axon injury persists for hours after spinal cord contusion in vivo.

Williams PR, Marincu BN, Sorbara CD, Mahler CF, Schumacher AM, Griesbeck O, Kerschensteiner M, Misgeld T.

Nat Commun. 2014 Dec 16;5:5683. doi: 10.1038/ncomms6683.

PMID:
25511170
25.

Pervasive axonal transport deficits in multiple sclerosis models.

Sorbara CD, Wagner NE, Ladwig A, Nikić I, Merkler D, Kleele T, Marinković P, Naumann R, Godinho L, Bareyre FM, Bishop D, Misgeld T, Kerschensteiner M.

Neuron. 2014 Dec 17;84(6):1183-90. doi: 10.1016/j.neuron.2014.11.006. Epub 2014 Nov 26.

26.

The use of a laser for correlating light and electron microscopic images in thick tissue specimens.

Bishop D, Nikic I, Kerschensteiner M, Misgeld T.

Methods Cell Biol. 2014;124:323-37. doi: 10.1016/B978-0-12-801075-4.00015-X.

PMID:
25287848
27.

An assay to image neuronal microtubule dynamics in mice.

Kleele T, Marinković P, Williams PR, Stern S, Weigand EE, Engerer P, Naumann R, Hartmann J, Karl RM, Bradke F, Bishop D, Herms J, Konnerth A, Kerschensteiner M, Godinho L, Misgeld T.

Nat Commun. 2014 Sep 12;5:4827. doi: 10.1038/ncomms5827.

28.

A unified cell biological perspective on axon-myelin injury.

Simons M, Misgeld T, Kerschensteiner M.

J Cell Biol. 2014 Aug 4;206(3):335-45. doi: 10.1083/jcb.201404154. Review.

29.

Multiparametric optical analysis of mitochondrial redox signals during neuronal physiology and pathology in vivo.

Breckwoldt MO, Pfister FM, Bradley PM, Marinković P, Williams PR, Brill MS, Plomer B, Schmalz A, St Clair DK, Naumann R, Griesbeck O, Schwarzländer M, Godinho L, Bareyre FM, Dick TP, Kerschensteiner M, Misgeld T.

Nat Med. 2014 May;20(5):555-60. doi: 10.1038/nm.3520. Epub 2014 Apr 20.

PMID:
24747747
30.

Neuroprotective approaches in the animal model.

Kerschensteiner M.

Drug Res (Stuttg). 2013 Nov;63 Suppl 1:S7. doi: 10.1055/s-0033-1346707. Epub 2013 Nov 15. No abstract available.

31.

Neuroprotective intervention by interferon-γ blockade prevents CD8+ T cell-mediated dendrite and synapse loss.

Kreutzfeldt M, Bergthaler A, Fernandez M, Brück W, Steinbach K, Vorm M, Coras R, Blümcke I, Bonilla WV, Fleige A, Forman R, Müller W, Becher B, Misgeld T, Kerschensteiner M, Pinschewer DD, Merkler D.

J Exp Med. 2013 Sep 23;210(10):2087-103. doi: 10.1084/jem.20122143. Epub 2013 Sep 2.

32.

STAT3 promotes corticospinal remodelling and functional recovery after spinal cord injury.

Lang C, Bradley PM, Jacobi A, Kerschensteiner M, Bareyre FM.

EMBO Rep. 2013 Oct;14(10):931-7. doi: 10.1038/embor.2013.117. Epub 2013 Aug 9.

33.

Cellular, subcellular and functional in vivo labeling of the spinal cord using vital dyes.

Romanelli E, Sorbara CD, Nikić I, Dagkalis A, Misgeld T, Kerschensteiner M.

Nat Protoc. 2013 Mar;8(3):481-90. doi: 10.1038/nprot.2013.022. Epub 2013 Feb 7.

PMID:
23391891
34.

In vivo imaging of the diseased nervous system: an update.

Sorbara C, Misgeld T, Kerschensteiner M.

Curr Pharm Des. 2012;18(29):4465-70. Review.

PMID:
22612742
35.

Axonal transport deficits and degeneration can evolve independently in mouse models of amyotrophic lateral sclerosis.

Marinkovic P, Reuter MS, Brill MS, Godinho L, Kerschensteiner M, Misgeld T.

Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4296-301. doi: 10.1073/pnas.1200658109. Epub 2012 Feb 27.

36.

Single collateral reconstructions reveal distinct phases of corticospinal remodeling after spinal cord injury.

Lang C, Guo X, Kerschensteiner M, Bareyre FM.

PLoS One. 2012;7(1):e30461. doi: 10.1371/journal.pone.0030461. Epub 2012 Jan 24.

37.

Near-infrared branding efficiently correlates light and electron microscopy.

Bishop D, Nikić I, Brinkoetter M, Knecht S, Potz S, Kerschensteiner M, Misgeld T.

Nat Methods. 2011 Jun 5;8(7):568-70. doi: 10.1038/nmeth.1622.

PMID:
21642966
38.

Age-dependent axonal transport and locomotor changes and tau hypophosphorylation in a "P301L" tau knockin mouse.

Gilley J, Seereeram A, Ando K, Mosely S, Andrews S, Kerschensteiner M, Misgeld T, Brion JP, Anderton B, Hanger DP, Coleman MP.

Neurobiol Aging. 2012 Mar;33(3):621.e1-621.e15. doi: 10.1016/j.neurobiolaging.2011.02.014. Epub 2011 Apr 13.

PMID:
21492964
39.

In vivo imaging reveals a phase-specific role of STAT3 during central and peripheral nervous system axon regeneration.

Bareyre FM, Garzorz N, Lang C, Misgeld T, Büning H, Kerschensteiner M.

Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6282-7. doi: 10.1073/pnas.1015239108. Epub 2011 Mar 29.

40.

A reversible form of axon damage in experimental autoimmune encephalomyelitis and multiple sclerosis.

Nikić I, Merkler D, Sorbara C, Brinkoetter M, Kreutzfeldt M, Bareyre FM, Brück W, Bishop D, Misgeld T, Kerschensteiner M.

Nat Med. 2011 Apr;17(4):495-9. doi: 10.1038/nm.2324. Epub 2011 Mar 27.

PMID:
21441916
41.

Voltage-dependent inwardly rectifying potassium conductance in the outer membrane of neuronal mitochondria.

Fieni F, Parkar A, Misgeld T, Kerschensteiner M, Lichtman JW, Pasinelli P, Trotti D.

J Biol Chem. 2010 Aug 27;285(35):27411-7. doi: 10.1074/jbc.M110.131243. Epub 2010 Jun 15.

42.

Neuro-immune crosstalk in CNS diseases.

Kerschensteiner M, Meinl E, Hohlfeld R.

Results Probl Cell Differ. 2010;51:197-216. doi: 10.1007/400_2009_6. Review.

PMID:
19343310
43.

Severely dystrophic axons at amyloid plaques remain continuous and connected to viable cell bodies.

Adalbert R, Nogradi A, Babetto E, Janeckova L, Walker SA, Kerschensteiner M, Misgeld T, Coleman MP.

Brain. 2009 Feb;132(Pt 2):402-16. doi: 10.1093/brain/awn312. Epub 2008 Dec 5.

PMID:
19059977
44.

Neuro-immune crosstalk in CNS diseases.

Kerschensteiner M, Meinl E, Hohlfeld R.

Neuroscience. 2009 Feb 6;158(3):1122-32. doi: 10.1016/j.neuroscience.2008.09.009. Epub 2008 Sep 13. Review.

PMID:
18848864
45.

Ex vivo imaging of motor axon dynamics in murine triangularis sterni explants.

Kerschensteiner M, Reuter MS, Lichtman JW, Misgeld T.

Nat Protoc. 2008;3(10):1645-53. doi: 10.1038/nprot.2008.160.

46.

Development of presynaptic inhibition onto retinal bipolar cell axon terminals is subclass-specific.

Schubert T, Kerschensteiner D, Eggers ED, Misgeld T, Kerschensteiner M, Lichtman JW, Lukasiewicz PD, Wong RO.

J Neurophysiol. 2008 Jul;100(1):304-16. doi: 10.1152/jn.90202.2008. Epub 2008 Apr 24.

47.

[Cellular imaging in the nervous system].

Kerschensteiner M, Misgeld T.

Dtsch Med Wochenschr. 2007 Nov;132(47):2529-33. Review. German. No abstract available.

PMID:
18027328
48.

Dual role of inflammation in CNS disease.

Hohlfeld R, Kerschensteiner M, Meinl E.

Neurology. 2007 May 29;68(22 Suppl 3):S58-63; discussion S91-6. Review.

PMID:
17548571
49.

Imaging axonal transport of mitochondria in vivo.

Misgeld T, Kerschensteiner M, Bareyre FM, Burgess RW, Lichtman JW.

Nat Methods. 2007 Jul;4(7):559-61. Epub 2007 Jun 10.

PMID:
17558414
50.

In vivo imaging of single axons in the mouse spinal cord.

Misgeld T, Nikic I, Kerschensteiner M.

Nat Protoc. 2007;2(2):263-8.

PMID:
17406584

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