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Quantitative analysis of individual cell-free DNA concentration before and after penetrating trauma.

Brodbeck K, Kern S, Schick S, Steinbrück A, Schwerer M, Bayer B, Anslinger K, Peldschus S.

Int J Legal Med. 2018 Oct 16. doi: 10.1007/s00414-018-1945-y. [Epub ahead of print]


Author response: Midlife cardiovascular fitness and dementia: A 44-year longitudinal population study in women.

Hörder H, Johansson L, Guo X, Grimby G, Kern S, Skoog I.

Neurology. 2018 Oct 16;91(16):763. doi: 10.1212/WNL.0000000000006350. No abstract available.


Increased Risk of Dementia in Subjective Cognitive Decline if CT Brain Changes are Present.

Sacuiu S, Eckerström M, Johansson L, Kern S, Sigström R, Xinxin G, Östling S, Skoog I.

J Alzheimers Dis. 2018 Sep 29. doi: 10.3233/JAD-180073. [Epub ahead of print]


Mechanism of sea-ice expansion in the Indian Ocean sector of Antarctica: Insights from satellite observation and model reanalysis.

Jena B, Kumar A, Ravichandran M, Kern S.

PLoS One. 2018 Oct 3;13(10):e0203222. doi: 10.1371/journal.pone.0203222. eCollection 2018.


Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis.

Lueschow SR, Stumphy J, Gong H, Kern SL, Elgin TG, Underwood MA, Kalanetra KM, Mills DA, Wong MH, Meyerholz DK, Good M, McElroy SJ.

PLoS One. 2018 Oct 1;13(10):e0204967. doi: 10.1371/journal.pone.0204967. eCollection 2018.


Attenuation of atherogenic apo B-48-dependent hyperlipidemia and high density lipoprotein remodeling induced by vitamin C and E combination and their beneficial effect on lethal ischemic heart disease in mice.

Contreras-Duarte S, Chen P, Andía M, Uribe S, Irarrázaval P, Kopp S, Kern S, Marsche G, Busso D, Wadsack C, Rigotti A.

Biol Res. 2018 Sep 15;51(1):34. doi: 10.1186/s40659-018-0183-6.


Structural Elucidation of Trace Components Combining GC/MS, GC/IR, DFT-Calculation and Synthesis-Salinilactones, Unprecedented Bicyclic Lactones from Salinispora Bacteria.

Schlawis C, Kern S, Kudo Y, Grunenberg J, Moore BS, Schulz S.

Angew Chem Int Ed Engl. 2018 Sep 10. doi: 10.1002/anie.201807923. [Epub ahead of print]


Midlife Stress in Relation to Late-Life Cerebrospinal Fluid Biomarkers of Alzheimer's Disease: A 25-Year Follow-Up Study.

Johansson L, Kern S, Zetterberg H, Blennow K, Börjesson-Hansson A, Rosengren L, Guo X, Skoog I.

Dement Geriatr Cogn Disord. 2018;46(1-2):90-99. doi: 10.1159/000490885. Epub 2018 Aug 24.


Multi-component relaxation in clinically isolated syndrome: Lesion myelination may predict multiple sclerosis conversion.

Kitzler HH, Wahl H, Eisele JC, Kuhn M, Schmitz-Peiffer H, Kern S, Rutt BK, Deoni SCL, Ziemssen T, Linn J.

Neuroimage Clin. 2018 May 31;20:61-70. doi: 10.1016/j.nicl.2018.05.034. eCollection 2018.


Negative Cognitions Following Distressing Unwanted Sex: The Role of Coercion Severity and Perceived Consent.

Kern SG, Peterson ZD.

J Interpers Violence. 2018 Aug 2:886260518790603. doi: 10.1177/0886260518790603. [Epub ahead of print]


In Vitro and In Vivo Activity of Amiodarone Against Ebola Virus.

Dyall J, Johnson JC, Hart BJ, Postnikova E, Cong Y, Zhou H, Gerhardt DM, Michelotti J, Honko AN, Kern S, DeWald LE, O'Loughlin KG, Green CE, Mirsalis JC, Bennett RS, Olinger GG Jr, Jahrling PB, Hensley LE.

J Infect Dis. 2018 Jul 16. doi: 10.1093/infdis/jiy345. [Epub ahead of print]


Increased risk for dementia both before and after stroke: A population-based study in women followed over 44 years.

Guo X, Östling S, Kern S, Johansson L, Skoog I.

Alzheimers Dement. 2018 Oct;14(10):1253-1260. doi: 10.1016/j.jalz.2018.05.009. Epub 2018 Jun 21.


A 10-Year Follow-Up of Adiposity and Dementia in Swedish Adults Aged 70 Years and Older.

Arnoldussen IAC, Sundh V, Bäckman K, Kern S, Östling S, Blennow K, Zetterberg H, Skoog I, Kiliaan AJ, Gustafson DR.

J Alzheimers Dis. 2018;63(4):1325-1335. doi: 10.3233/JAD-180099.


Prevalence of preclinical Alzheimer disease: Comparison of current classification systems.

Kern S, Zetterberg H, Kern J, Zettergren A, Waern M, Höglund K, Andreasson U, Wetterberg H, Börjesson-Hanson A, Blennow K, Skoog I.

Neurology. 2018 May 8;90(19):e1682-e1691. doi: 10.1212/WNL.0000000000005476. Epub 2018 Apr 13.


Online low-field NMR spectroscopy for process control of an industrial lithiation reaction-automated data analysis.

Kern S, Meyer K, Guhl S, Gräßer P, Paul A, King R, Maiwald M.

Anal Bioanal Chem. 2018 May;410(14):3349-3360. doi: 10.1007/s00216-018-1020-z. Epub 2018 Apr 4.


Low Cerebrospinal Fluid Aβ42 and Aβ40 are Related to White Matter Lesions in Cognitively Normal Elderly.

Skoog I, Kern S, Zetterberg H, Östling S, Börjesson-Hanson A, Guo X, Blennow K.

J Alzheimers Dis. 2018;62(4):1877-1886. doi: 10.3233/JAD-170950.


Folate receptor-directed orthogonal click-functionalization of siRNA lipopolyplexes for tumor cell killing in vivo.

Klein PM, Kern S, Lee DJ, Schmaus J, Höhn M, Gorges J, Kazmaier U, Wagner E.

Biomaterials. 2018 Sep;178:630-642. doi: 10.1016/j.biomaterials.2018.03.031. Epub 2018 Mar 19.


Midlife cardiovascular fitness and dementia: A 44-year longitudinal population study in women.

Hörder H, Johansson L, Guo X, Grimby G, Kern S, Östling S, Skoog I.

Neurology. 2018 Apr 10;90(15):e1298-e1305. doi: 10.1212/WNL.0000000000005290. Epub 2018 Mar 14.


Genetic Variation in FOXO3 is Associated with Self-Rated Health in a Population-Based Sample of Older Individuals.

Zettergren A, Kern S, Rydén L, Östling S, Blennow K, Zetterberg H, Falk H, Skoog I.

J Gerontol A Biol Sci Med Sci. 2018 Oct 8;73(11):1453-1458. doi: 10.1093/gerona/gly021.


Fatigue and Sleep in Multiple Sclerosis Patients: A Comparison of Self-Report and Performance-Based Measures.

Paucke M, Kern S, Ziemssen T.

Front Neurol. 2018 Jan 4;8:703. doi: 10.3389/fneur.2017.00703. eCollection 2017.


Description of a Mass Poisoning in a Rural District in Mozambique: The First Documented Bongkrekic Acid Poisoning in Africa.

Gudo ES, Cook K, Kasper AM, Vergara A, Salomão C, Oliveira F, Ismael H, Saeze C, Mosse C, Fernandes Q, Viegas SO, Baltazar CS, Doyle TJ, Yard E, Steck A, Serret M, Falconer TM, Kern SE, Brzezinski JL, Turner JA, Boyd BL, Jani IV; Chitima Investigation Group.

Clin Infect Dis. 2018 Apr 17;66(9):1400-1406. doi: 10.1093/cid/cix1005.


Trends in the incidence of dementia: design and methods in the Alzheimer Cohorts Consortium.

Chibnik LB, Wolters FJ, Bäckman K, Beiser A, Berr C, Bis JC, Boerwinkle E, Bos D, Brayne C, Dartigues JF, Darweesh SKL, Debette S, Davis-Plourde KL, Dufouil C, Fornage M, Grasset L, Gudnason V, Hadjichrysanthou C, Helmer C, Ikram MA, Ikram MK, Kern S, Kuller LH, Launer L, Lopez OL, Matthews F, Meirelles O, Mosley T, Ower A, Psaty BM, Satizabal CL, Seshadri S, Skoog I, Stephan BCM, Tzourio C, Waziry R, Wong MM, Zettergren A, Hofman A.

Eur J Epidemiol. 2017 Oct;32(10):931-938. doi: 10.1007/s10654-017-0320-5. Epub 2017 Oct 23.


Model-Informed Drug Development for Malaria Therapeutics.

Andrews KA, Wesche D, McCarthy J, Möhrle JJ, Tarning J, Phillips L, Kern S, Grasela T.

Annu Rev Pharmacol Toxicol. 2018 Jan 6;58:567-582. doi: 10.1146/annurev-pharmtox-010715-103429. Epub 2017 Oct 6.


p-Alkyl-Benzoyl-CoA Conjugates as Relevant Metabolites of Aromatic Aldehydes With Rat Testicular Toxicity-Studies Leading to the Design of a Safer New Fragrance Chemical.

Laue H, Kern S, Badertscher RP, Ellis G, Natsch A.

Toxicol Sci. 2017 Dec 1;160(2):244-255. doi: 10.1093/toxsci/kfx178.


Impact of Endothelial Lipase on Cholesterol Efflux Capacity of Serum and High-density Lipoprotein.

Schilcher I, Kern S, Hrzenjak A, Eichmann TO, Stojakovic T, Scharnagl H, Duta-Mare M, Kratky D, Marsche G, Frank S.

Sci Rep. 2017 Oct 2;7(1):12485. doi: 10.1038/s41598-017-12882-7.


A New Clinically Relevant T-Score Standard to Interpret Bone Status in a Sheep Model.

Heiss C, Kern S, Malhan D, Böcker W, Engelhardt M, Daghma DES, Stoetzel S, Schmitt J, Ivo M, Kauschke V, Lips KS, Tushtev K, Rezwan K, El Khassawna T.

Med Sci Monit Basic Res. 2017 Oct 2;23:326-335.


Adiponectin Predicts High-Density Lipoprotein Cholesterol Efflux Capacity in Adults Irrespective of Body Mass Index and Fat Distribution.

Marsche G, Zelzer S, Meinitzer A, Kern S, Meissl S, Pregartner G, Weghuber D, Almer G, Mangge H.

J Clin Endocrinol Metab. 2017 Nov 1;102(11):4117-4123. doi: 10.1210/jc.2017-00933.


HDL structure and function is profoundly affected when stored frozen in the absence of cryoprotectants.

Holzer M, Kern S, Trieb M, Trakaki A, Marsche G.

J Lipid Res. 2017 Nov;58(11):2220-2228. doi: 10.1194/jlr.D075366. Epub 2017 Sep 11.


Effects of Standardized Home Training in Patients with Cognitive Impairment following Geriatric Rehabilitation: A Randomized Controlled Pilot Study.

Hauer K, Ullrich P, Dutzi I, Beurskens R, Kern S, Bauer J, Schwenk M.

Gerontology. 2017;63(6):495-506. doi: 10.1159/000478263. Epub 2017 Aug 17.


Decreasing prevalence of dementia in 85-year olds examined 22 years apart: the influence of education and stroke.

Skoog I, Börjesson-Hanson A, Kern S, Johansson L, Falk H, Sigström R, Östling S.

Sci Rep. 2017 Jul 21;7(1):6136. doi: 10.1038/s41598-017-05022-8.


Deleterious Effects of Chronic Folate Deficiency in the Ts65Dn Mouse Model of Down Syndrome.

Helm S, Blayney M, Whited T, Noroozi M, Lin S, Kern S, Green D, Salehi A.

Front Cell Neurosci. 2017 Jun 9;11:161. doi: 10.3389/fncel.2017.00161. eCollection 2017.


Interventions for alcohol-related risky sexual behaviors among college students: A systematic review.

Kilwein TM, Kern SM, Looby A.

Psychol Addict Behav. 2017 Dec;31(8):944-950. doi: 10.1037/adb0000294. Epub 2017 Jun 22. Review.


Osteocyte Regulation of Receptor Activator of NF-κB Ligand/Osteoprotegerin in a Sheep Model of Osteoporosis.

El Khassawna T, Merboth F, Malhan D, Böcker W, Daghma DES, Stoetzel S, Kern S, Hassan F, Rosenbaum D, Langenstein J, Bauer N, Schlagenhauf A, Rösen-Wolff A, Schulze F, Rupp M, Hose D, Secklinger A, Ignatius A, Wilke HJ, Lips KS, Heiss C.

Am J Pathol. 2017 Aug;187(8):1686-1699. doi: 10.1016/j.ajpath.2017.04.005. Epub 2017 Jun 12.


Forensic Analysis of Stains on Fabric Using Direct Analysis in Real-time Ionization with High-Resolution Accurate Mass-Mass Spectrometry.

Kern SE, Crowe JB, Litzau JJ, Heitkemper DT.

J Forensic Sci. 2018 Mar;63(2):592-597. doi: 10.1111/1556-4029.13565. Epub 2017 Jun 12.


Computational segmentation of collagen fibers in bone matrix indicates bone quality in ovariectomized rat spine.

Daghma DES, Malhan D, Simon P, Stötzel S, Kern S, Hassan F, Lips KS, Heiss C, El Khassawna T.

J Bone Miner Metab. 2018 May;36(3):297-306. doi: 10.1007/s00774-017-0844-5. Epub 2017 Jun 6.


Postembedding Decalcification of Mineralized Tissue Sections Preserves the Integrity of Implanted Biomaterials and Minimizes Number of Experimental Animals.

El Khassawna T, Daghma DES, Stoetzel S, Ray S, Kern S, Malhan D, Alt V, Thormann U, Henß A, Rohnke M, Stengel A, Hassan F, Maenz S, Jandt KD, Diefenbeck M, Schumacher M, Gelinsky M, Lips KS, Heiss C.

Biomed Res Int. 2017;2017:2023853. doi: 10.1155/2017/2023853. Epub 2017 Mar 23.


Sex differences in time trends of blood pressure among Swedish septuagenarians examined three decades apart: a longitudinal population study.

Joas E, Guo X, Kern S, Östling S, Skoog I.

J Hypertens. 2017 Jul;35(7):1424-1431. doi: 10.1097/HJH.0000000000001348.


Sequence-Defined Oligoamide Drug Conjugates of Pretubulysin and Methotrexate for Folate Receptor Targeted Cancer Therapy.

Truebenbach I, Gorges J, Kuhn J, Kern S, Baratti E, Kazmaier U, Wagner E, Lächelt U.

Macromol Biosci. 2017 Oct;17(10). doi: 10.1002/mabi.201600520. Epub 2017 Mar 30.


Multi-infarct dementia of Swedish type is caused by a 3'UTR mutation of COL4A1.

Siitonen M, Börjesson-Hanson A, Pöyhönen M, Ora A, Pasanen P, Bras J, Kern S, Kern J, Andersen O, Stanescu H, Kleta R, Baumann M, Kalaria R, Kalimo H, Singleton A, Hardy J, Viitanen M, Myllykangas L, Guerreiro R.

Brain. 2017 May 1;140(5):e29. doi: 10.1093/brain/awx062. No abstract available.


"Click" analytics for "click" chemistry - A simple method for calibration-free evaluation of online NMR spectra.

Michalik-Onichimowska A, Kern S, Riedel J, Panne U, King R, Maiwald M.

J Magn Reson. 2017 Apr;277:154-161. doi: 10.1016/j.jmr.2017.02.018. Epub 2017 Mar 1.


Erratum to: Characterization and pathogenesis of aerosolized eastern equine encephalitis in the common marmoset (Callithrix jacchus).

Porter AI, Erwin-Cohen RA, Twenhafel N, Chance T, Yee SB, Kern SJ, Norwood D, Hartman LJ, Parker MD, Glass PJ, DaSilva L.

Virol J. 2017 Mar 10;14(1):51. doi: 10.1186/s12985-017-0717-5. No abstract available.


Perceived social support in adults with autism spectrum disorder and attention-deficit/hyperactivity disorder.

Alvarez-Fernandez S, Brown HR, Zhao Y, Raithel JA, Bishop SL, Kern SB, Lord C, Petkova E, Di Martino A.

Autism Res. 2017 May;10(5):866-877. doi: 10.1002/aur.1735. Epub 2017 Mar 3.


Author response: Calcium supplementation and risk of dementia in women with cerebrovascular disease.

Kern S, Kern J, Blennow K, Zetterberg H, Waern M, Guo X, Börjesson-Hanson A, Skoog I, Östling S.

Neurology. 2017 Feb 21;88(8):813. doi: 10.1212/WNL.0000000000003646. No abstract available.


CSF YKL-40 and GAP-43 are related to suicidal ideation in older women.

Rymo I, Kern S, Bjerke M, Zetterberg H, Marlow T, Blennow K, Gudmundsson P, Skoog I, Waern M.

Acta Psychiatr Scand. 2017 Apr;135(4):351-357. doi: 10.1111/acps.12701. Epub 2017 Feb 17.


The safety and efficacy of baclofen to reduce alcohol use in veterans with chronic hepatitis C: a randomized controlled trial.

Hauser P, Fuller B, Ho SB, Thuras P, Kern S, Dieperink E.

Addiction. 2017 Jul;112(7):1173-1183. doi: 10.1111/add.13787. Epub 2017 Apr 2.


Two stable variants of Burkholderia pseudomallei strain MSHR5848 express broadly divergent in vitro phenotypes associated with their virulence differences.

Shea AA, Bernhards RC, Cote CK, Chase CJ, Koehler JW, Klimko CP, Ladner JT, Rozak DA, Wolcott MJ, Fetterer DP, Kern SJ, Koroleva GI, Lovett SP, Palacios GF, Toothman RG, Bozue JA, Worsham PL, Welkos SL.

PLoS One. 2017 Feb 10;12(2):e0171363. doi: 10.1371/journal.pone.0171363. eCollection 2017.


Characterization and pathogenesis of aerosolized eastern equine encephalitis in the common marmoset (Callithrix jacchus).

Porter AI, Erwin-Cohen RA, Twenhafel N, Chance T, Yee SB, Kern SJ, Norwood D, Hartman LJ, Parker MD, Glass PJ, DaSilva L.

Virol J. 2017 Feb 7;14(1):25. doi: 10.1186/s12985-017-0687-7. Erratum in: Virol J. 2017 Mar 10;14 (1):51.


HDL Cholesterol Efflux Capacity and Cardiovascular Events in Patients With Chronic Kidney Disease.

Bauer L, Kern S, Rogacev KS, Emrich IE, Zawada A, Fliser D, Heinemann A, Heine GH, Marsche G.

J Am Coll Cardiol. 2017 Jan 17;69(2):246-247. doi: 10.1016/j.jacc.2016.10.054. No abstract available.


Preclinical amyloid pathology biomarker positivity: effects on tau pathology and neurodegeneration.

Höglund K, Kern S, Zettergren A, Börjesson-Hansson A, Zetterberg H, Skoog I, Blennow K.

Transl Psychiatry. 2017 Jan 10;7(1):e995. doi: 10.1038/tp.2016.252.


Economic Evaluation of Pharmacologic Pre- and Postconditioning With Sevoflurane Compared With Total Intravenous Anesthesia in Liver Surgery: A Cost Analysis.

Eichler K, Urner M, Twerenbold C, Kern S, Brügger U, Spahn DR, Beck-Schimmer B, Ganter MT.

Anesth Analg. 2017 Mar;124(3):925-933. doi: 10.1213/ANE.0000000000001814.

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