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Items: 50

1.

High Cks1 expression in transgenic and carcinogen-initiated mammary tumors is not always accompanied by reduction in p27Kip1.

Westbrook L, Ramanathan HN, Isayeva T, Mittal AR, Qu Z, Johnson MD, Kern FG, Ponnazhagan S, Grubbs CJ, Thottassery JV.

Int J Oncol. 2009 May;34(5):1425-31.

PMID:
19360356
2.

Vascular endothelial growth factor reduces tamoxifen efficacy and promotes metastatic colonization and desmoplasia in breast tumors.

Qu Z, Van Ginkel S, Roy AM, Westbrook L, Nasrin M, Maxuitenko Y, Frost AR, Carey D, Wang W, Li R, Grizzle WE, Thottassery JV, Kern FG.

Cancer Res. 2008 Aug 1;68(15):6232-40. doi: 10.1158/0008-5472.CAN-07-5654.

3.

Cks1 regulates cdk1 expression: a novel role during mitotic entry in breast cancer cells.

Westbrook L, Manuvakhova M, Kern FG, Estes NR 2nd, Ramanathan HN, Thottassery JV.

Cancer Res. 2007 Dec 1;67(23):11393-401.

4.

Activation loop phosphorylation-independent kinase activity of human protein kinase C zeta.

Ranganathan S, Wang Y, Kern FG, Qu Z, Li R.

Proteins. 2007 May 15;67(3):709-19.

PMID:
17335005
5.

MEK ablation in MCF-7 cells blocks DNA synthesis induced by serum, but not by estradiol or growth factors.

Estes NR 2nd, Thottassery JV, Westbrook L, Kern FG.

Int J Oncol. 2006 Dec;29(6):1573-80.

PMID:
17088999
7.

Expression of the SNT-1/FRS2 phosphotyrosine binding domain inhibits activation of MAP kinase and PI3-kinase pathways and antiestrogen resistant growth induced by FGF-1 in human breast carcinoma cells.

Manuvakhova M, Thottassery JV, Hays S, Qu Z, Rentz SS, Westbrook L, Kern FG.

Oncogene. 2006 Sep 28;25(44):6003-14. Epub 2006 May 8.

PMID:
16682955
9.

Homogeneity and long-term stability of tetracycline-regulated gene expression with low basal activity by using the rtTA2S-M2 transactivator and insulator-flanked reporter vectors.

Qu Z, Thottassery JV, Van Ginkel S, Manuvakhova M, Westbrook L, Roland-Lazenby C, Hays S, Kern FG.

Gene. 2004 Feb 18;327(1):61-73.

PMID:
14960361
10.

Pro-matrix metalloproteinase-2 transfection increases orthotopic primary growth and experimental metastasis of MDA-MB-231 human breast cancer cells in nude mice.

Tester AM, Waltham M, Oh SJ, Bae SN, Bills MM, Walker EC, Kern FG, Stetler-Stevenson WG, Lippman ME, Thompson EW.

Cancer Res. 2004 Jan 15;64(2):652-8.

11.

Fibroblast growth factors (FGFS) increase breast tumor growth rate, metastases, blood flow, and oxygenation without significant change in vascular density.

Okunieff P, Fenton BM, Zhang L, Kern FG, Wu T, Greg JR, Ding I.

Adv Exp Med Biol. 2003;530:593-601.

PMID:
14562756
12.

Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells.

Oh AS, Lorant LA, Holloway JN, Miller DL, Kern FG, El-Ashry D.

Mol Endocrinol. 2001 Aug;15(8):1344-59.

PMID:
11463858
13.

Expression and function of angiopoietin-1 in breast cancer.

Hayes AJ, Huang WQ, Yu J, Maisonpierre PC, Liu A, Kern FG, Lippman ME, McLeskey SW, Li LY.

Br J Cancer. 2000 Nov;83(9):1154-60.

15.
16.

Tamoxifen-resistant fibroblast growth factor-transfected MCF-7 cells are cross-resistant in vivo to the antiestrogen ICI 182,780 and two aromatase inhibitors.

McLeskey SW, Zhang L, El-Ashry D, Trock BJ, Lopez CA, Kharbanda S, Tobias CA, Lorant LA, Hannum RS, Dickson RB, Kern FG.

Clin Cancer Res. 1998 Mar;4(3):697-711.

18.

MCF-7 breast carcinoma cells overexpressing FGF-1 form vascularized, metastatic tumors in ovariectomized or tamoxifen-treated nude mice.

Zhang L, Kharbanda S, Chen D, Bullocks J, Miller DL, Ding IY, Hanfelt J, McLeskey SW, Kern FG.

Oncogene. 1997 Oct 23;15(17):2093-108.

19.

Constitutive Raf-1 kinase activity in breast cancer cells induces both estrogen-independent growth and apoptosis.

El-Ashry D, Miller DL, Kharbanda S, Lippman ME, Kern FG.

Oncogene. 1997 Jul 24;15(4):423-35.

20.

Estrogen induction of TGF-alpha is mediated by an estrogen response element composed of two imperfect palindromes.

El-Ashry D, Chrysogelos SA, Lippman ME, Kern FG.

J Steroid Biochem Mol Biol. 1996 Nov;59(3-4):261-9.

PMID:
9010318
21.

The role of angiogenic growth factors in breast cancer progression.

Kern FG, Lippman ME.

Cancer Metastasis Rev. 1996 Jun;15(2):213-9. Review. No abstract available.

PMID:
8842493
22.

Effects of AGM-1470 and pentosan polysulphate on tumorigenicity and metastasis of FGF-transfected MCF-7 cells.

McLeskey SW, Zhang L, Trock BJ, Kharbanda S, Liu Y, Gottardis MM, Lippman ME, Kern FG.

Br J Cancer. 1996 May;73(9):1053-62.

23.

Fibroblast growth factor overexpressing breast carcinoma cells as models of angiogenesis and metastasis.

McLeskey SW, Zhang L, Kharbanda S, Kurebayashi J, Lippman ME, Dickson RB, Kern FG.

Breast Cancer Res Treat. 1996;39(1):103-17.

PMID:
8738610
26.

Fibroblast growth factor-4 enhanced G2 arrest and cell survival following ionizing radiation.

Jung M, Kern FG, Jorgensen TJ, McLeskey SW, Blair OC, Dritschilo A.

Cancer Res. 1994 Oct 1;54(19):5194-7.

27.
28.

Transfected MCF-7 cells as a model for breast-cancer progression.

Kern FG, McLeskey SW, Zhang L, Kurebayashi J, Liu Y, Ding IY, Kharbanda S, Chen D, Miller D, Cullen K, et al.

Breast Cancer Res Treat. 1994;31(2-3):153-65. Review.

PMID:
7881095
29.

Quantitative demonstration of spontaneous metastasis by MCF-7 human breast cancer cells cotransfected with fibroblast growth factor 4 and LacZ.

Kurebayashi J, McLeskey SW, Johnson MD, Lippman ME, Dickson RB, Kern FG.

Cancer Res. 1993 May 1;53(9):2178-87.

30.

Fibroblast growth factor 4 transfection of MCF-7 cells produces cell lines that are tumorigenic and metastatic in ovariectomized or tamoxifen-treated athymic nude mice.

McLeskey SW, Kurebayashi J, Honig SF, Zwiebel J, Lippman ME, Dickson RB, Kern FG.

Cancer Res. 1993 May 1;53(9):2168-77.

31.

Overexpression of transforming growth factor alpha overrides the glucocorticoid-mediated suppression of Con8 mammary tumor cell growth in vitro and in vivo.

Goya L, Alexander DB, Webster MK, Kern FG, Guzman RC, Nandi S, Firestone GL.

Cancer Res. 1993 Apr 15;53(8):1816-22.

32.
33.

Immunohistochemical analysis of p53 and HER-2/neu proteins in human tumors.

Chang K, Ding I, Kern FG, Willingham MC.

J Histochem Cytochem. 1991 Sep;39(9):1281-7.

PMID:
1680897
34.

Human ADP-ribosylation factors. A functionally conserved family of GTP-binding proteins.

Kahn RA, Kern FG, Clark J, Gelmann EP, Rulka C.

J Biol Chem. 1991 Feb 5;266(4):2606-14.

35.

Growth factor receptors and the progression of breast cancer.

Kern FG, Cheville AL, Liu YL.

Semin Cancer Biol. 1990 Oct;1(5):317-28. Review.

PMID:
1966491
36.

Autocrine growth stimulation by secreted Kaposi fibroblast growth factor but not by endogenous basic fibroblast growth factor.

Wellstein A, Lupu R, Zugmaier G, Flamm SL, Cheville AL, Delli Bovi P, Basilico C, Lippman ME, Kern FG.

Cell Growth Differ. 1990 Feb;1(2):63-71.

37.

Endocrine therapy of human breast cancer cells: the role of secreted polypeptide growth factors.

Brünner N, Zugmaier G, Bano M, Ennis BW, Clarke R, Cullen KJ, Kern FG, Dickson RB, Lippman ME.

Cancer Cells. 1989 Nov;1(3):81-6. Review.

PMID:
2701652
38.

The effects of a constitutive expression of transforming growth factor-alpha on the growth of MCF-7 human breast cancer cells in vitro and in vivo.

Clarke R, Brünner N, Katz D, Glanz P, Dickson RB, Lippman ME, Kern FG.

Mol Endocrinol. 1989 Feb;3(2):372-80.

PMID:
2710138
39.
40.

DNA sequence requirements for replication of polyomavirus DNA in vivo and in vitro.

Prives C, Murakami Y, Kern FG, Folk W, Basilico C, Hurwitz J.

Mol Cell Biol. 1987 Oct;7(10):3694-704.

41.

An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family.

Delli Bovi P, Curatola AM, Kern FG, Greco A, Ittmann M, Basilico C.

Cell. 1987 Aug 28;50(5):729-37.

PMID:
2957062
42.

Adenovirus E1a proteins repress expression from polyomavirus early and late promoters.

Velcich A, Kern FG, Basilico C, Ziff EB.

Mol Cell Biol. 1986 Nov;6(11):4019-25.

43.

Regulation of polyomavirus late promoter activity by viral early proteins.

Kern FG, Pellegrini S, Cowie A, Basilico C.

J Virol. 1986 Oct;60(1):275-85.

46.
48.

Cell differentiation rates of Friend murine erythroleukemia variants isolated by sib selection.

Axelrod DE, Terry R, Kern FG.

Somatic Cell Genet. 1979 Sep;5(5):539-49.

PMID:
294699
49.

Ozone detoxification of paralytic shellfish poison in the softshell clam (Mya arenaria).

Blogoslawski WJ, Stewart ME, Hurst JW Jr, Kern FG 3rd.

Toxicon. 1979;17(6):650-4. No abstract available.

PMID:
524392
50.

Epizootic neoplasms in the clam Macoma balthica (L.) from Chesapeake Bay.

Christensen DJ, Farley CA, Kern FG.

J Natl Cancer Inst. 1974 Jun;52(6):1739-49. No abstract available.

PMID:
4834406

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