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Items: 46


Comprehensive Real-World Assessment of Marketed Medications to Guide Parkinson's Drug Discovery.

Cepeda MS, Kern DM, Seabrook GR, Lovestone S.

Clin Drug Investig. 2019 Jul 20. doi: 10.1007/s40261-019-00830-4. [Epub ahead of print]


Incidence and Prevalence of Microvascular and Macrovascular Diseases and All-cause Mortality in Type 2 Diabetes Mellitus: A 10-year Study in a US Commercially Insured and Medicare Advantage Population.

Visaria J, Iyer NN, Raval A, Kong S, Hobbs T, Bouchard J, Kern DM, Willey V.

Clin Ther. 2019 Jun 10. pii: S0149-2918(19)30257-7. doi: 10.1016/j.clinthera.2019.05.012. [Epub ahead of print]


Health Plan Enrollment and Disenrollment of Individuals With and Without Established Chronic Disease in a U.S. Commercially Insured and Medicare Advantage Population.

Chung H, Deshpande G, Zolotarjova J, Quimbo RA, Kern DM, Cochetti PT, Willey VJ.

J Manag Care Spec Pharm. 2019 May;25(5):612-620. doi: 10.18553/jmcp.2019.25.5.612.


Cryo-EM structures of the DCPIB-inhibited volume-regulated anion channel LRRC8A in lipid nanodiscs.

Kern DM, Oh S, Hite RK, Brohawn SG.

Elife. 2019 Feb 18;8. pii: e42636. doi: 10.7554/eLife.42636.


Ectopic Activation of the Spindle Assembly Checkpoint Signaling Cascade Reveals Its Biochemical Design.

Chen C, Whitney IP, Banerjee A, Sacristan C, Sekhri P, Kern DM, Fontan A, Kops GJPL, Tyson JJ, Cheeseman IM, Joglekar AP.

Curr Biol. 2019 Jan 7;29(1):104-119.e10. doi: 10.1016/j.cub.2018.11.054. Epub 2018 Dec 27.


Bridging the Gap Between Self-Reported and Claims-Derived Adherence Measures for Basal Insulin Among Patients with Type 2 Diabetes Mellitus.

Stephenson JJ, Bae JP, Raval AD, Kern DM.

Adv Ther. 2019 Jan;36(1):118-130. doi: 10.1007/s12325-018-0828-4. Epub 2018 Dec 7.


Treatment patterns among patients with psoriasis using a large national payer database in the United States: a retrospective study.

Murage MJ, Kern DM, Chang L, Sonawane K, Malatestinic WN, Quimbo RA, Feldman SR, Muram TM, Araujo AB.

J Med Econ. 2018 Oct 25:1-9. doi: 10.1080/13696998.2018.1540424. [Epub ahead of print]


Non-adherence to basal insulin among patients with type 2 diabetes in a US managed care population: Results from a patient survey.

Stephenson JJ, Raval AD, Kern DM, Bae JP.

Diabetes Obes Metab. 2018 Nov;20(11):2700-2704. doi: 10.1111/dom.13446. Epub 2018 Jul 22.


Treatment Patterns of Newly Diagnosed Rheumatoid Arthritis Patients from a Commercially Insured Population.

Kern DM, Chang L, Sonawane K, Larmore CJ, Boytsov NN, Quimbo RA, Singer J, Hinton JT, Wu SJ, Araujo AB.

Rheumatol Ther. 2018 Dec;5(2):355-369. doi: 10.1007/s40744-018-0114-6. Epub 2018 May 30.


Neighborhood Prices of Healthier and Unhealthier Foods and Associations with Diet Quality: Evidence from the Multi-Ethnic Study of Atherosclerosis.

Kern DM, Auchincloss AH, Stehr MF, Roux AVD, Moore LV, Kanter GP, Robinson LF.

Int J Environ Res Public Health. 2017 Nov 16;14(11). pii: E1394. doi: 10.3390/ijerph14111394.


Neighborhood price of healthier food relative to unhealthy food and its association with type 2 diabetes and insulin resistance: The multi-ethnic study of atherosclerosis.

Kern DM, Auchincloss AH, Stehr MF, Diez Roux AV, Moore KA, Kanter GP, Robinson LF.

Prev Med. 2018 Jan;106:122-129. doi: 10.1016/j.ypmed.2017.10.029. Epub 2017 Oct 26.


Real-World Treatment Sequences and Outcomes Among Patients With Non-Small Cell Lung Cancer (RESOUNDS) in the United States: Study Protocol.

Hess LM, Kern DM, Carter GC, Winfree K, Wang L, Sontag A, Oton AB.

JMIR Res Protoc. 2017 Oct 11;6(10):e195. doi: 10.2196/resprot.7750.


A validation of clinical data captured from a novel Cancer Care Quality Program directly integrated with administrative claims data.

Kern DM, Barron JJ, Wu B, Ganetsky A, Willey VJ, Quimbo RA, Fisch MJ, Singer J, Nguyen A, Mamtani R.

Pragmat Obs Res. 2017 Aug 26;8:149-155. doi: 10.2147/POR.S140579. eCollection 2017.


Astrin-SKAP complex reconstitution reveals its kinetochore interaction with microtubule-bound Ndc80.

Kern DM, Monda JK, Su KC, Wilson-Kubalek EM, Cheeseman IM.

Elife. 2017 Aug 25;6. pii: e26866. doi: 10.7554/eLife.26866.


Longitudinal Associations of Local Cigarette Prices and Smoking Bans with Smoking Behavior in the Multi-Ethnic Study of Atherosclerosis.

Mayne SL, Auchincloss AH, Stehr MF, Kern DM, Navas-Acien A, Kaufman JD, Michael YL, Diez Roux AV.

Epidemiology. 2017 Nov;28(6):863-871. doi: 10.1097/EDE.0000000000000736.


Healthy and Unhealthy Food Prices across Neighborhoods and Their Association with Neighborhood Socioeconomic Status and Proportion Black/Hispanic.

Kern DM, Auchincloss AH, Robinson LF, Stehr MF, Pham-Kanter G.

J Urban Health. 2017 Aug;94(4):494-505. doi: 10.1007/s11524-017-0168-8.


Impact of Nonadherence to Inhaled Corticosteroid/LABA Therapy on COPD Exacerbation Rates and Healthcare Costs in a Commercially Insured US Population.

Davis JR, Wu B, Kern DM, Tunceli O, Fox KM, Horton J, Legg RF, Trudo F.

Am Health Drug Benefits. 2017 Apr;10(2):92-102.


Initiation Patterns of Statins in the 2 Years After Release of the 2013 American College of Cardiology/American Heart Association (ACC/AHA) Cholesterol Management Guideline in a Large US Health Plan.

Olufade T, Zhou S, Anzalone D, Kern DM, Tunceli O, Cziraky MJ, Willey VJ.

J Am Heart Assoc. 2017 May 4;6(5). pii: e005205. doi: 10.1161/JAHA.116.005205.


Ethnic Identity and Perceived Stress Among Ethnically Diverse Immigrants.

Espinosa A, Tikhonov A, Ellman LM, Kern DM, Lui F, Anglin D.

J Immigr Minor Health. 2018 Feb;20(1):155-163. doi: 10.1007/s10903-016-0494-z.


Increased Burden of Healthcare Utilization and Cost Associated with Opioid-Related Constipation Among Patients with Noncancer Pain.

Fernandes AW, Kern DM, Datto C, Chen YW, McLeskey C, Tunceli O.

Am Health Drug Benefits. 2016 May;9(3):160-70.


Neighbourhood variation in the price of soda relative to milk and its association with neighbourhood socio-economic status and race.

Kern DM, Auchincloss AH, Ballester LS, Robinson LF.

Public Health Nutr. 2016 Dec;19(18):3386-3396. Epub 2016 Jun 30.


A mitotic SKAP isoform regulates spindle positioning at astral microtubule plus ends.

Kern DM, Nicholls PK, Page DC, Cheeseman IM.

J Cell Biol. 2016 May 9;213(3):315-28. doi: 10.1083/jcb.201510117. Epub 2016 May 2.


Understanding CKD among patients with T2DM: prevalence, temporal trends, and treatment patterns-NHANES 2007-2012.

Wu B, Bell K, Stanford A, Kern DM, Tunceli O, Vupputuri S, Kalsekar I, Willey V.

BMJ Open Diabetes Res Care. 2016 Apr 11;4(1):e000154. doi: 10.1136/bmjdrc-2015-000154. eCollection 2016.


Health Care Utilization and Costs After Initiating Budesonide/Formoterol Combination or Fluticasone/Salmeterol Combination Among COPD Patients New to ICS/LABA Treatment.

Davis JR, Kern DM, Williams SA, Tunceli O, Wu B, Hollis S, Strange C, Trudo F.

J Manag Care Spec Pharm. 2016 Mar;22(3):293-304. doi: 10.18553/jmcp.2016.22.3.293.


Long-term cardiovascular risk and costs for myocardial infarction survivors in a US commercially insured population.

Kern DM, Mellström C, Hunt PR, Tunceli O, Wu B, Westergaard M, Hammar N.

Curr Med Res Opin. 2016;32(4):703-11. doi: 10.1185/03007995.2015.1136607. Epub 2016 Feb 10.


Comparative effectiveness of budesonide/formoterol combination and tiotropium bromide among COPD patients new to these controller treatments.

Trudo F, Kern DM, Davis JR, Tunceli O, Zhou S, Graham EL, Strange C, Williams SA.

Int J Chron Obstruct Pulmon Dis. 2015 Sep 28;10:2055-66. doi: 10.2147/COPD.S90658. eCollection 2015.


Asthma and Chronic Obstructive Pulmonary Disease Overlap Syndrome: Doubled Costs Compared with Patients with Asthma Alone.

Gerhardsson de Verdier M, Andersson M, Kern DM, Zhou S, Tunceli O.

Value Health. 2015 Sep;18(6):759-66. doi: 10.1016/j.jval.2015.04.010. Epub 2015 Jun 22.


Validation of an administrative claims-based diagnostic code for pneumonia in a US-based commercially insured COPD population.

Kern DM, Davis J, Williams SA, Tunceli O, Wu B, Hollis S, Strange C, Trudo F.

Int J Chron Obstruct Pulmon Dis. 2015 Jul 23;10:1417-25. doi: 10.2147/COPD.S83135. eCollection 2015.


Healthcare utilization and costs associated with S. aureus and P. aeruginosa pneumonia in the intensive care unit: a retrospective observational cohort study in a US claims database.

Kyaw MH, Kern DM, Zhou S, Tunceli O, Jafri HS, Falloon J.

BMC Health Serv Res. 2015 Jun 21;15:241. doi: 10.1186/s12913-015-0917-x.


Treatment patterns, healthcare utilization, and costs of chronic opioid treatment for non-cancer pain in the United States.

Kern DM, Zhou S, Chavoshi S, Tunceli O, Sostek M, Singer J, LoCasale RJ.

Am J Manag Care. 2015 Mar 1;21(3):e222-34.


Comparative effectiveness of budesonide-formoterol combination and fluticasone-salmeterol combination for asthma management: a United States retrospective database analysis.

Tunceli O, Williams SA, Kern DM, Elhefni H, Pethick N, Wessman C, Zhou S, Trudo F.

J Allergy Clin Immunol Pract. 2014 Nov-Dec;2(6):719-26. doi: 10.1016/j.jaip.2014.07.016. Epub 2014 Oct 3.


The outer kinetochore protein KNL-1 contains a defined oligomerization domain in nematodes.

Kern DM, Kim T, Rigney M, Hattersley N, Desai A, Cheeseman IM.

Mol Biol Cell. 2015 Jan 15;26(2):229-37. doi: 10.1091/mbc.E14-06-1125. Epub 2014 Nov 19.


Statin treatment patterns and clinical profile of patients with risk factors for coronary heart disease defined by National Cholesterol Education Program Adult Treatment Panel III.

Kern DM, Balu S, Tunceli O, Anzalone D.

Curr Med Res Opin. 2014 Dec;30(12):2443-51. doi: 10.1185/03007995.2014.971151. Epub 2014 Oct 14.


A US database study characterizing patients initiating a budesonide-formoterol combination versus tiotropium bromide as initial maintenance therapy for chronic obstructive pulmonary disease.

Kern DM, Williams SA, Tunceli O, Wessman C, Zhou S, Pethick N, Elhefni H, Trudo F.

Int J Chron Obstruct Pulmon Dis. 2014 Jul 18;9:775-83. doi: 10.2147/COPD.S64491. eCollection 2014.


Description of cardiovascular event rates in patients initiating chronic opioid therapy for noncancer pain in observational cohort studies in the US, UK, and Germany.

LoCasale R, Kern DM, Chevalier P, Zhou S, Chavoshi S, Sostek M.

Adv Ther. 2014 Jul;31(7):708-23. doi: 10.1007/s12325-014-0131-y. Epub 2014 Jul 18.


Kinetochore genes are coordinately up-regulated in human tumors as part of a FoxM1-related cell division program.

Thiru P, Kern DM, McKinley KL, Monda JK, Rago F, Su KC, Tsinman T, Yarar D, Bell GW, Cheeseman IM.

Mol Biol Cell. 2014 Jul 1;25(13):1983-94. doi: 10.1091/mbc.E14-03-0837. Epub 2014 May 14.


A rapid, inexpensive, and semi-quantitative method for determining pollen tube extension using fluorescence.

Hartman E, Levy C, Kern DM, Johnson MA, Basu A.

Plant Methods. 2014 Jan 23;10(1):3. doi: 10.1186/1746-4811-10-3.


Spindle assembly checkpoint robustness requires Tpr-mediated regulation of Mad1/Mad2 proteostasis.

Schweizer N, Ferrás C, Kern DM, Logarinho E, Cheeseman IM, Maiato H.

J Cell Biol. 2013 Dec 23;203(6):883-93.


Treatment pattern changes in high-risk patients newly initiated on statin monotherapy in a managed care setting.

Simpson RJ Jr, Tunceli K, Ramey DR, Neff DR, Kern DM, Hsieh HM, Wertz DA, Stephenson JJ, Marrett E, Tomassini JE, Jacobson TA.

J Clin Lipidol. 2013 Sep-Oct;7(5):399-407. doi: 10.1016/j.jacl.2013.06.002. Epub 2013 Jun 18.


Impact of natalizumab on patient-reported outcomes in multiple sclerosis: a longitudinal study.

Stephenson JJ, Kern DM, Agarwal SS, Zeidman R, Rajagopalan K, Kamat SA, Foley J.

Health Qual Life Outcomes. 2012 Dec 27;10:155. doi: 10.1186/1477-7525-10-155.


Kinetochore structure: pulling answers from yeast.

Kern DM, Cheeseman IM.

Curr Biol. 2012 Oct 9;22(19):R842-4. doi: 10.1016/j.cub.2012.08.001.


Low maternal hemoglobin during pregnancy and diminished neuromotor and neurocognitive performance in offspring with schizophrenia.

Ellman LM, Vinogradov S, Kremen WS, Poole JH, Kern DM, Deicken RF, Brown AS.

Schizophr Res. 2012 Jun;138(1):81-7. doi: 10.1016/j.schres.2012.04.008. Epub 2012 May 17.


T cell activation and senescence predict subclinical carotid artery disease in HIV-infected women.

Kaplan RC, Sinclair E, Landay AL, Lurain N, Sharrett AR, Gange SJ, Xue X, Hunt P, Karim R, Kern DM, Hodis HN, Deeks SG.

J Infect Dis. 2011 Feb 15;203(4):452-63. doi: 10.1093/infdis/jiq071. Epub 2011 Jan 10.


Structural brain alterations in schizophrenia following fetal exposure to the inflammatory cytokine interleukin-8.

Ellman LM, Deicken RF, Vinogradov S, Kremen WS, Poole JH, Kern DM, Tsai WY, Schaefer CA, Brown AS.

Schizophr Res. 2010 Aug;121(1-3):46-54. doi: 10.1016/j.schres.2010.05.014. Epub 2010 Jun 9.


Socialization to violence among the aged.

Dowd JJ, Sisson RP, Kern DM.

J Gerontol. 1981 May;36(3):350-61.


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