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Items: 19

1.

Low serum lathosterol levels associate with fatal cardiovascular disease and excess all-cause mortality: a prospective cohort study.

Weingärtner O, Lütjohann D, Meyer S, Fuhrmann A, Cremers B, Seiler-Mußler S, Schött HF, Kerksiek A, Friedrichs S, Ulbricht U, Zawada A, Laufs U, Schulze PC, Scheller B, Fliser D, Böhm M, Sijbrands E, Heine GH.

Clin Res Cardiol. 2019 Apr 4. doi: 10.1007/s00392-019-01474-2. [Epub ahead of print]

PMID:
30949753
2.

First international descriptive and interventional survey for cholesterol and non-cholesterol sterol determination by gas- and liquid-chromatography-Urgent need for harmonisation of analytical methods.

Lütjohann D, Björkhem I, Friedrichs S, Kerksiek A, Lövgren-Sandblom A, Geilenkeuser WJ, Ahrends R, Andrade I, Ansorena D, Astiasarán I, Baila-Rueda L, Barriuso B, Becker S, Bretillon L, Browne RW, Caccia C, Ceglarek U, Cenarro A, Crick PJ, Fauler G, Garcia-Llatas G, Gray R, Griffiths WJ, Gylling H, Harding S, Helmschrodt C, Iuliano L, Janssen HG, Jones P, Kaipiainen L, Kannenberg F, Lagarda MJ, Leoni V, Lottenberg AM, MacKay DS, Matysik S, McDonald J, Menendez-Carreño M, Myrie SB, Sutti Nunes V, Ostlund RE, Polisecki E, Ramos F, Rideout TC, Schaefer EJ, Schmitz G, Wang Y, Zerbinati C, Diczfalusy U, Schött HF.

J Steroid Biochem Mol Biol. 2019 Jun;190:115-125. doi: 10.1016/j.jsbmb.2019.03.025. Epub 2019 Mar 30.

3.

Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer's disease mouse model.

Bogie J, Hoeks C, Schepers M, Tiane A, Cuypers A, Leijten F, Chintapakorn Y, Suttiyut T, Pornpakakul S, Struik D, Kerksiek A, Liu HB, Hellings N, Martinez-Martinez P, Jonker JW, Dewachter I, Sijbrands E, Walter J, Hendriks J, Groen A, Staels B, Lütjohann D, Vanmierlo T, Mulder M.

Sci Rep. 2019 Mar 20;9(1):4908. doi: 10.1038/s41598-019-41399-4.

4.

Plasma levels of the oxyphytosterol 7α-hydroxycampesterol are associated with cardiovascular events.

Fuhrmann A, Weingärtner O, Meyer S, Cremers B, Seiler-Mußler S, Schött HF, Kerksiek A, Friedrichs S, Ulbricht U, Zawada AM, Laufs U, Scheller B, Fliser D, Schulze PC, Böhm M, Heine GH, Lütjohann D.

Atherosclerosis. 2018 Dec;279:17-22. doi: 10.1016/j.atherosclerosis.2018.10.010. Epub 2018 Oct 17.

PMID:
30366187
5.

International descriptive and interventional survey for oxycholesterol determination by gas- and liquid-chromatographic methods.

Lütjohann D, Björkhem I, Friedrichs S, Kerksiek A, Geilenkeuser WJ, Lövgren-Sandblom A, Ansorena D, Astiasarán I, Baila-Rueda L, Barriuso B, Bretillon L, Browne RW, Caccia C, Cenarro A, Crick PJ, Fauler G, García-Llatas G, Griffiths WJ, Iuliano L, Lagarda MJ, Leoni V, Lottenberg AM, Matysik S, McDonald J, Rideout TC, Schmitz G, Nunes VS, Wang Y, Zerbinati C, Diczfalusy U, Schött HF.

Biochimie. 2018 Oct;153:26-32. doi: 10.1016/j.biochi.2018.07.016. Epub 2018 Jul 29.

PMID:
30063945
6.

Identification of Correlative Shifts in Indices of Brain Cholesterol Metabolism in the C57BL6/Mecp2tm1.1Bird Mouse, a Model for Rett Syndrome.

Lütjohann D, Lopez AM, Chuang JC, Kerksiek A, Turley SD.

Lipids. 2018 Apr;53(4):363-373. doi: 10.1002/lipd.12041. Epub 2018 May 17.

PMID:
29770459
7.

Ursodeoxycholic acid impairs atherogenesis and promotes plaque regression by cholesterol crystal dissolution in mice.

Bode N, Grebe A, Kerksiek A, Lütjohann D, Werner N, Nickenig G, Latz E, Zimmer S.

Biochem Biophys Res Commun. 2016 Sep 9;478(1):356-362. doi: 10.1016/j.bbrc.2016.07.047. Epub 2016 Jul 11.

PMID:
27416761
8.

Deleting myeloid IL-10 receptor signalling attenuates atherosclerosis in LDLR-/- mice by altering intestinal cholesterol fluxes.

Stöger JL, Boshuizen MC, Brufau G, Gijbels MJ, Wolfs IM, van der Velden S, Pöttgens CC, Vergouwe MN, Wijnands E, Beckers L, Goossens P, Kerksiek A, Havinga R, Müller W, Lütjohann D, Groen AK, de Winther MP.

Thromb Haemost. 2016 Aug 30;116(3):565-77. doi: 10.1160/TH16-01-0043. Epub 2016 Jun 30.

PMID:
27358035
9.

Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming.

Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, Björkhem I, Gustafsson JÅ, Westerterp M, Tall AR, Wright SD, Espevik T, Schultze JL, Nickenig G, Lütjohann D, Latz E.

Sci Transl Med. 2016 Apr 6;8(333):333ra50. doi: 10.1126/scitranslmed.aad6100.

10.

Dietary plant stanol ester consumption improves immune function in asthma patients: results of a randomized, double-blind clinical trial.

Brüll F, De Smet E, Mensink RP, Vreugdenhil A, Kerksiek A, Lütjohann D, Wesseling G, Plat J.

Am J Clin Nutr. 2016 Feb;103(2):444-53. doi: 10.3945/ajcn.115.117531. Epub 2016 Jan 13.

PMID:
26762374
11.

Acute intake of plant stanol esters induces changes in lipid and lipoprotein metabolism-related gene expression in the liver and intestines of mice.

De Smet E, Mensink RP, Konings M, Brufau G, Groen AK, Havinga R, Schonewille M, Kerksiek A, Lütjohann D, Plat J.

Lipids. 2015 Jun;50(6):529-41. doi: 10.1007/s11745-015-4020-1. Epub 2015 May 1.

12.

High-density lipoprotein mediates anti-inflammatory reprogramming of macrophages via the transcriptional regulator ATF3.

De Nardo D, Labzin LI, Kono H, Seki R, Schmidt SV, Beyer M, Xu D, Zimmer S, Lahrmann C, Schildberg FA, Vogelhuber J, Kraut M, Ulas T, Kerksiek A, Krebs W, Bode N, Grebe A, Fitzgerald ML, Hernandez NJ, Williams BR, Knolle P, Kneilling M, Röcken M, Lütjohann D, Wright SD, Schultze JL, Latz E.

Nat Immunol. 2014 Feb;15(2):152-60. doi: 10.1038/ni.2784. Epub 2013 Dec 8.

13.

Dietary intake of plant sterols stably increases plant sterol levels in the murine brain.

Vanmierlo T, Weingärtner O, van der Pol S, Husche C, Kerksiek A, Friedrichs S, Sijbrands E, Steinbusch H, Grimm M, Hartmann T, Laufs U, Böhm M, de Vries HE, Mulder M, Lütjohann D.

J Lipid Res. 2012 Apr;53(4):726-35. doi: 10.1194/jlr.M017244. Epub 2012 Jan 25.

14.

Intrahepatic cholesterol influences progression, inhibition and reversal of non-alcoholic steatohepatitis in hyperlipidemic mice.

Wouters K, van Bilsen M, van Gorp PJ, Bieghs V, Lütjohann D, Kerksiek A, Staels B, Hofker MH, Shiri-Sverdlov R.

FEBS Lett. 2010 Mar 5;584(5):1001-5. doi: 10.1016/j.febslet.2010.01.046. Epub 2010 Jan 29.

15.

Alterations in brain cholesterol metabolism in the APPSLxPS1mut mouse, a model for Alzheimer's disease.

Vanmierlo T, Bloks VW, van Vark-van der Zee LC, Rutten K, Kerksiek A, Friedrichs S, Sijbrands E, Steinbusch HW, Kuipers F, Lütjohann D, Mulder M.

J Alzheimers Dis. 2010;19(1):117-27. doi: 10.3233/JAD-2010-1209.

PMID:
20061631
16.

Dietary cholesterol, rather than liver steatosis, leads to hepatic inflammation in hyperlipidemic mouse models of nonalcoholic steatohepatitis.

Wouters K, van Gorp PJ, Bieghs V, Gijbels MJ, Duimel H, Lütjohann D, Kerksiek A, van Kruchten R, Maeda N, Staels B, van Bilsen M, Shiri-Sverdlov R, Hofker MH.

Hepatology. 2008 Aug;48(2):474-86. doi: 10.1002/hep.22363.

PMID:
18666236
17.

Altered levels of plasma 24S- and 27-hydroxycholesterol in demented patients.

Kölsch H, Heun R, Kerksiek A, Bergmann KV, Maier W, Lütjohann D.

Neurosci Lett. 2004 Sep 30;368(3):303-8.

PMID:
15364416
18.

SREBP-1a polymorphism influences the risk of Alzheimer's disease in carriers of the ApoE4 allele.

Spell C, Kölsch H, Lütjohann D, Kerksiek A, Hentschel F, Damian M, von Bergmann K, Rao ML, Maier W, Heun R.

Dement Geriatr Cogn Disord. 2004;18(3-4):245-9. Epub 2004 Jul 29.

PMID:
15286454
19.

Carbamazepine increases atherogenic lipoproteins: mechanism of action in male adults.

Brämswig S, Kerksiek A, Sudhop T, Luers C, Von Bergmann K, Berthold HK.

Am J Physiol Heart Circ Physiol. 2002 Feb;282(2):H704-16.

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