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Items: 43

1.

RELN signaling modulates glioblastoma growth and substrate-dependent migration.

Schulze M, Violonchi C, Swoboda S, Welz T, Kerkhoff E, Hoja S, Brüggemann S, Simbürger J, Reinders J, Riemenschneider MJ.

Brain Pathol. 2018 Sep;28(5):695-709. doi: 10.1111/bpa.12584. Epub 2018 Jan 10.

PMID:
29222813
2.

Actin assembly mechanisms at a glance.

Rottner K, Faix J, Bogdan S, Linder S, Kerkhoff E.

J Cell Sci. 2017 Oct 15;130(20):3427-3435. doi: 10.1242/jcs.206433. Review.

3.

Exploring the iceberg: Prospects of coordinated myosin V and actin assembly functions in transport processes.

Welz T, Kerkhoff E.

Small GTPases. 2019 Mar;10(2):111-121. doi: 10.1080/21541248.2017.1281863. Epub 2017 Apr 10.

4.

A Genome-Wide siRNA Screen Implicates Spire1/2 in SipA-Driven Salmonella Typhimurium Host Cell Invasion.

Andritschke D, Dilling S, Emmenlauer M, Welz T, Schmich F, Misselwitz B, Rämö P, Rottner K, Kerkhoff E, Wada T, Penninger JM, Beerenwinkel N, Horvath P, Dehio C, Hardt WD.

PLoS One. 2016 Sep 14;11(9):e0161965. doi: 10.1371/journal.pone.0161965. eCollection 2016.

5.

Coordinated recruitment of Spir actin nucleators and myosin V motors to Rab11 vesicle membranes.

Pylypenko O, Welz T, Tittel J, Kollmar M, Chardon F, Malherbe G, Weiss S, Michel CI, Samol-Wolf A, Grasskamp AT, Hume A, Goud B, Baron B, England P, Titus MA, Schwille P, Weidemann T, Houdusse A, Kerkhoff E.

Elife. 2016 Sep 13;5. pii: e17523. doi: 10.7554/eLife.17523.

6.

Membrane targeting of the Spir·formin actin nucleator complex requires a sequential handshake of polar interactions.

Tittel J, Welz T, Czogalla A, Dietrich S, Samol-Wolf A, Schulte M, Schwille P, Weidemann T, Kerkhoff E.

J Biol Chem. 2015 Mar 6;290(10):6428-44. doi: 10.1074/jbc.M114.602672. Epub 2015 Jan 6.

7.

Orchestration of cell surface proteins by Rab11.

Welz T, Wellbourne-Wood J, Kerkhoff E.

Trends Cell Biol. 2014 Jul;24(7):407-15. doi: 10.1016/j.tcb.2014.02.004. Epub 2014 Mar 24. Review.

PMID:
24675420
8.

Enhanced fear expression in Spir-1 actin organizer mutant mice.

Pleiser S, Banchaabouchi MA, Samol-Wolf A, Farley D, Welz T, Wellbourne-Wood J, Gehring I, Linkner J, Faix J, Riemenschneider MJ, Dietrich S, Kerkhoff E.

Eur J Cell Biol. 2014 May-Jun;93(5-6):225-37. doi: 10.1016/j.ejcb.2013.11.001. Epub 2013 Nov 20.

PMID:
24345451
9.

Structural and functional insights into the Spir/formin actin nucleator complex.

Dietrich S, Weiß S, Pleiser S, Kerkhoff E.

Biol Chem. 2013 Dec;394(12):1649-60. doi: 10.1515/hsz-2013-0176. Review.

PMID:
23863697
10.

Molecular basis of actin nucleation factor cooperativity: crystal structure of the Spir-1 kinase non-catalytic C-lobe domain (KIND)•formin-2 formin SPIR interaction motif (FSI) complex.

Zeth K, Pechlivanis M, Samol A, Pleiser S, Vonrhein C, Kerkhoff E.

J Biol Chem. 2011 Sep 2;286(35):30732-9. doi: 10.1074/jbc.M111.257782. Epub 2011 Jun 26.

11.

Spire-type actin nucleators cooperate with Formin-2 to drive asymmetric oocyte division.

Pfender S, Kuznetsov V, Pleiser S, Kerkhoff E, Schuh M.

Curr Biol. 2011 Jun 7;21(11):955-60. doi: 10.1016/j.cub.2011.04.029. Epub 2011 May 27.

12.

Microtubules as platforms for assaying actin polymerization in vivo.

Oelkers JM, Vinzenz M, Nemethova M, Jacob S, Lai FP, Block J, Szczodrak M, Kerkhoff E, Backert S, Schlüter K, Stradal TE, Small JV, Koestler SA, Rottner K.

PLoS One. 2011;6(5):e19931. doi: 10.1371/journal.pone.0019931. Epub 2011 May 16.

13.

Actin dynamics at intracellular membranes: the Spir/formin nucleator complex.

Kerkhoff E.

Eur J Cell Biol. 2011 Nov;90(11):922-5. doi: 10.1016/j.ejcb.2010.10.011. Epub 2010 Dec 3. Review.

PMID:
21129813
14.

Expression patterns of the mouse Spir-2 actin nucleator.

Pleiser S, Rock R, Wellmann J, Gessler M, Kerkhoff E.

Gene Expr Patterns. 2010 Oct-Dec;10(7-8):345-50. doi: 10.1016/j.gep.2010.08.001. Epub 2010 Aug 17.

PMID:
20723621
15.

Identification of a short Spir interaction sequence at the C-terminal end of formin subgroup proteins.

Pechlivanis M, Samol A, Kerkhoff E.

J Biol Chem. 2009 Sep 11;284(37):25324-33. doi: 10.1074/jbc.M109.030320. Epub 2009 Jul 15.

16.

Actin nucleation: bacteria get in-Spired.

Quinlan ME, Kerkhoff E.

Nat Cell Biol. 2008 Jan;10(1):13-5. doi: 10.1038/ncb0108-13. No abstract available.

PMID:
18172428
17.

Regulatory interactions between two actin nucleators, Spire and Cappuccino.

Quinlan ME, Hilgert S, Bedrossian A, Mullins RD, Kerkhoff E.

J Cell Biol. 2007 Oct 8;179(1):117-28.

18.

Cellular functions of the Spir actin-nucleation factors.

Kerkhoff E.

Trends Cell Biol. 2006 Sep;16(9):477-83. Epub 2006 Aug 9. Review.

PMID:
16901698
19.

Very-KIND is a novel nervous system specific guanine nucleotide exchange factor for Ras GTPases.

Mees A, Rock R, Ciccarelli FD, Leberfinger CB, Borawski JM, Bork P, Wiese S, Gessler M, Kerkhoff E.

Gene Expr Patterns. 2005 Dec;6(1):79-85. Epub 2005 Aug 15.

PMID:
16099729
20.

Drosophila Spire is an actin nucleation factor.

Quinlan ME, Heuser JE, Kerkhoff E, Mullins RD.

Nature. 2005 Jan 27;433(7024):382-8.

PMID:
15674283
21.

Overlapping expression pattern of the actin organizers Spir-1 and formin-2 in the developing mouse nervous system and the adult brain.

Schumacher N, Borawski JM, Leberfinger CB, Gessler M, Kerkhoff E.

Gene Expr Patterns. 2004 May;4(3):249-55.

PMID:
15053972
22.

The KIND module: a putative signalling domain evolved from the C lobe of the protein kinase fold.

Ciccarelli FD, Bork P, Kerkhoff E.

Trends Biochem Sci. 2003 Jul;28(7):349-52. No abstract available.

PMID:
12877999
23.

Constitutive JNK activation in NIH 3T3 fibroblasts induces a partially transformed phenotype.

Rennefahrt UE, Illert B, Kerkhoff E, Troppmair J, Rapp UR.

J Biol Chem. 2002 Aug 16;277(33):29510-8. Epub 2002 May 30.

24.

Phospholipase D overcomes cell cycle arrest induced by high-intensity Raf signaling.

Joseph T, Bryant A, Frankel P, Wooden R, Kerkhoff E, Rapp UR, Foster DA.

Oncogene. 2002 May 16;21(22):3651-8.

25.

Diverse effects of RacV12 on cell transformation by Raf: partial inhibition of morphological transformation versus deregulation of cell cycle control.

Kerkhoff E, Leberfinger CB, Schmidt G, Aktories K, Rapp UR.

Biochim Biophys Acta. 2002 Apr 3;1589(2):151-9.

26.

The Spir actin organizers are involved in vesicle transport processes.

Kerkhoff E, Simpson JC, Leberfinger CB, Otto IM, Doerks T, Bork P, Rapp UR, Raabe T, Pepperkok R.

Curr Biol. 2001 Dec 11;11(24):1963-8.

27.

The Ras-Raf relationship: an unfinished puzzle.

Kerkhoff E, Rapp UR.

Adv Enzyme Regul. 2001;41:261-7. Review. No abstract available.

PMID:
11384750
28.

Lung-targeted expression of the c-Raf-1 kinase in transgenic mice exposes a novel oncogenic character of the wild-type protein.

Kerkhoff E, Fedorov LM, Siefken R, Walter AO, Papadopoulos T, Rapp UR.

Cell Growth Differ. 2000 Apr;11(4):185-90.

29.

The p150-Spir protein provides a link between c-Jun N-terminal kinase function and actin reorganization.

Otto IM, Raabe T, Rennefahrt UE, Bork P, Rapp UR, Kerkhoff E.

Curr Biol. 2000 Mar 23;10(6):345-8.

30.

Ral and Rho-dependent activation of phospholipase D in v-Raf-transformed cells.

Frankel P, Ramos M, Flom J, Bychenok S, Joseph T, Kerkhoff E, Rapp UR, Feig LA, Foster DA.

Biochem Biophys Res Commun. 1999 Feb 16;255(2):502-7.

PMID:
10049738
31.

Cell cycle targets of Ras/Raf signalling.

Kerkhoff E, Rapp UR.

Oncogene. 1998 Sep 17;17(11 Reviews):1457-62. Review.

32.

High-intensity Raf signals convert mitotic cell cycling into cellular growth.

Kerkhoff E, Rapp UR.

Cancer Res. 1998 Apr 15;58(8):1636-40.

33.

Regulation of c-myc expression by Ras/Raf signalling.

Kerkhoff E, Houben R, Löffler S, Troppmair J, Lee JE, Rapp UR.

Oncogene. 1998 Jan 15;16(2):211-6.

34.
35.

Deregulated messenger RNA expression during T cell apoptosis.

Kerkhoff E, Ziff EB.

Nucleic Acids Res. 1995 Dec 11;23(23):4857-63.

37.

Leukemia risk following Hodgkin's disease: relation to cumulative dose of alkylating agents, treatment with teniposide combinations, number of episodes of chemotherapy, and bone marrow damage.

van Leeuwen FE, Chorus AM, van den Belt-Dusebout AW, Hagenbeek A, Noyon R, van Kerkhoff EH, Pinedo HM, Somers R.

J Clin Oncol. 1994 May;12(5):1063-73.

PMID:
8164031
38.

Second cancer risk following Hodgkin's disease: a 20-year follow-up study.

van Leeuwen FE, Klokman WJ, Hagenbeek A, Noyon R, van den Belt-Dusebout AW, van Kerkhoff EH, van Heerde P, Somers R.

J Clin Oncol. 1994 Feb;12(2):312-25.

PMID:
8113838
39.

Second cancer risk following testicular cancer: a follow-up study of 1,909 patients.

van Leeuwen FE, Stiggelbout AM, van den Belt-Dusebout AW, Noyon R, Eliel MR, van Kerkhoff EH, Delemarre JF, Somers R.

J Clin Oncol. 1993 Mar;11(3):415-24.

PMID:
8445415
40.

Influence of age and comorbidity on treatment choice and survival in elderly patients with breast cancer.

Bergman L, Dekker G, van Kerkhoff EH, Peterse HL, van Dongen JA, van Leeuwen FE.

Breast Cancer Res Treat. 1991 Aug;18(3):189-98.

PMID:
1756262
41.

Sequence-specific DNA binding by Myc proteins.

Kerkhoff E, Bister K, Klempnauer KH.

Proc Natl Acad Sci U S A. 1991 May 15;88(10):4323-7.

42.

Myc protein structure: localization of DNA-binding and protein dimerization domains.

Kerkhoff E, Bister K.

Oncogene. 1991 Jan;6(1):93-102.

PMID:
1992448
43.

Cloning of the breakpoints of a deletion associated with choroidermia.

Cremers FP, Brunsmann F, Berger W, van Kerkhoff EP, van de Pol TJ, Wieringa B, Pawlowitzki IH, Ropers HH.

Hum Genet. 1990 Nov;86(1):61-4.

PMID:
1979308

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