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Molecular Evolution of IDH Wild-Type Glioblastomas Treated With Standard of Care Affects Survival and Design of Precision Medicine Trials: A Report From the EORTC 1542 Study.

Draaisma K, Chatzipli A, Taphoorn M, Kerkhof M, Weyerbrock A, Sanson M, Hoeben A, Lukacova S, Lombardi G, Leenstra S, Hanse M, Fleischeuer R, Watts C, McAbee J, Angelopoulos N, Gorlia T, Golfinopoulos V, Kros JM, Verhaak RGW, Bours V, van den Bent MJ, McDermott U, Robe PA, French PJ.

J Clin Oncol. 2020 Jan 1;38(1):81-99. doi: 10.1200/JCO.19.00367. Epub 2019 Nov 19.


Comparative effectiveness of triple therapy versus dual bronchodilation in COPD.

Voorham J, Corradi M, Papi A, Vogelmeier CF, Singh D, Fabbri LM, Kerkhof M, Kocks JH, Carter V, Price D.

ERJ Open Res. 2019 Aug 30;5(3). pii: 00106-2019. doi: 10.1183/23120541.00106-2019. eCollection 2019 Jul.


Withdrawal of antiepileptic drugs in patients with low grade and anaplastic glioma after long-term seizure freedom: a prospective observational study.

Kerkhof M, Koekkoek JAF, Vos MJ, van den Bent MJ, Taal W, Postma TJ, Bromberg JEC, Kouwenhoven MCM, Dirven L, Reijneveld JC, Taphoorn MJB.

J Neurooncol. 2019 May;142(3):463-470. doi: 10.1007/s11060-019-03117-y. Epub 2019 Feb 18.



De Ligny WR, Kerkhof MH, Ruiz-Zapata AM.

Am J Obstet Gynecol. 2019 Mar;220(3):292. doi: 10.1016/j.ajog.2018.12.025. Epub 2018 Dec 21. No abstract available.


Immunosuppression of Syrian golden hamsters accelerates relapse but not the emergence of resistance in Leishmania infantum following recurrent miltefosine pressure.

Hendrickx S, Bulté D, Van den Kerkhof M, Cos P, Delputte P, Maes L, Caljon G.

Int J Parasitol Drugs Drug Resist. 2019 Apr;9:1-7. doi: 10.1016/j.ijpddr.2018.12.001. Epub 2018 Dec 11.


IUGA committee opinion: laser-based vaginal devices for treatment of stress urinary incontinence, genitourinary syndrome of menopause, and vaginal laxity.

Shobeiri SA, Kerkhof MH, Minassian VA, Bazi T; IUGA Research and Development Committee.

Int Urogynecol J. 2019 Mar;30(3):371-376. doi: 10.1007/s00192-018-3830-0. Epub 2018 Dec 6. Review.


Miltefosine enhances the fitness of a non-virulent drug-resistant Leishmania infantum strain.

Eberhardt E, Bulté D, Van Bockstal L, Van den Kerkhof M, Cos P, Delputte P, Hendrickx S, Maes L, Caljon G.

J Antimicrob Chemother. 2019 Feb 1;74(2):395-406. doi: 10.1093/jac/dky450.


Regenerative medicine as a therapeutic option for fecal incontinence: a systematic review of preclinical and clinical studies.

De Ligny WR, Kerkhof MH, Ruiz-Zapata AM.

Am J Obstet Gynecol. 2019 Feb;220(2):142-154.e2. doi: 10.1016/j.ajog.2018.09.009. Epub 2018 Sep 26.


Adverse outcomes from initiation of systemic corticosteroids for asthma: long-term observational study.

Price DB, Trudo F, Voorham J, Xu X, Kerkhof M, Ling Zhi Jie J, Tran TN.

J Asthma Allergy. 2018 Aug 29;11:193-204. doi: 10.2147/JAA.S176026. eCollection 2018.


Impact of primary mouse macrophage cell types on Leishmania infection and in vitro drug susceptibility.

Van den Kerkhof M, Van Bockstal L, Gielis JF, Delputte P, Cos P, Maes L, Caljon G, Hendrickx S.

Parasitol Res. 2018 Nov;117(11):3601-3612. doi: 10.1007/s00436-018-6059-4. Epub 2018 Aug 23.


Pedunculated Morphology of T1 Colorectal Tumors Associates With Reduced Risk of Adverse Outcome.

Kessels K, Backes Y, Elias SG, van den Blink A, Offerhaus GJA, van Bergeijk JD, Groen JN, Seerden TCJ, Schwartz MP, de Vos Tot Nederveen Cappel WH, Spanier BWM, Geesing JMJ, Kerkhof M, Siersema PD, Didden P, Boonstra JJ, Herrero LA, Wolfhagen FHJ, Ter Borg F, van Lent AU, Terhaar Sive Droste JS, Hazen WL, Schrauwen RWM, Vleggaar FP, Laclé MM, Moons LMG; Dutch T1 Colorectal Cancer Working Group.

Clin Gastroenterol Hepatol. 2019 May;17(6):1112-1120.e1. doi: 10.1016/j.cgh.2018.08.041. Epub 2018 Aug 18.


Association between blood eosinophil count and risk of readmission for patients with asthma: Historical cohort study.

Kerkhof M, Tran TN, van den Berge M, Brusselle GG, Gopalan G, Jones RCM, Kocks JWH, Menzies-Gow A, Nuevo J, Pavord ID, Rastogi S, Price DB.

PLoS One. 2018 Jul 25;13(7):e0201143. doi: 10.1371/journal.pone.0201143. eCollection 2018.


Healthcare resource utilization and costs associated with incremental systemic corticosteroid exposure in asthma.

Voorham J, Xu X, Price DB, Golam S, Davis J, Zhi Jie Ling J, Kerkhof M, Ow M, Tran TN.

Allergy. 2019 Feb;74(2):273-283. doi: 10.1111/all.13556. Epub 2018 Nov 20.


Clozapine and Long-Term Mortality Risk in Patients With Schizophrenia: A Systematic Review and Meta-analysis of Studies Lasting 1.1-12.5 Years.

Vermeulen JM, van Rooijen G, van de Kerkhof MPJ, Sutterland AL, Correll CU, de Haan L.

Schizophr Bull. 2019 Mar 7;45(2):315-329. doi: 10.1093/schbul/sby052.


Atopic dermatitis: Interaction between genetic variants of GSTP1, TNF, TLR2, and TLR4 and air pollution in early life.

Hüls A, Klümper C, MacIntyre EA, Brauer M, Melén E, Bauer M, Berdel D, Bergström A, Brunekreef B, Chan-Yeung M, Fuertes E, Gehring U, Gref A, Heinrich J, Standl M, Lehmann I, Kerkhof M, Koppelman GH, Kozyrskyj AL, Pershagen G, Carlsten C, Krämer U, Schikowski T; TAG Study Group.

Pediatr Allergy Immunol. 2018 Sep;29(6):596-605. doi: 10.1111/pai.12903. Epub 2018 May 7.


DNA methylation in childhood asthma: an epigenome-wide meta-analysis.

Xu CJ, Söderhäll C, Bustamante M, Baïz N, Gruzieva O, Gehring U, Mason D, Chatzi L, Basterrechea M, Llop S, Torrent M, Forastiere F, Fantini MP, Carlsen KCL, Haahtela T, Morin A, Kerkhof M, Merid SK, van Rijkom B, Jankipersadsing SA, Bonder MJ, Ballereau S, Vermeulen CJ, Aguirre-Gamboa R, de Jongste JC, Smit HA, Kumar A, Pershagen G, Guerra S, Garcia-Aymerich J, Greco D, Reinius L, McEachan RRC, Azad R, Hovland V, Mowinckel P, Alenius H, Fyhrquist N, Lemonnier N, Pellet J, Auffray C; BIOS Consortium, van der Vlies P, van Diemen CC, Li Y, Wijmenga C, Netea MG, Moffatt MF, Cookson WOCM, Anto JM, Bousquet J, Laatikainen T, Laprise C, Carlsen KH, Gori D, Porta D, Iñiguez C, Bilbao JR, Kogevinas M, Wright J, Brunekreef B, Kere J, Nawijn MC, Annesi-Maesano I, Sunyer J, Melén E, Koppelman GH.

Lancet Respir Med. 2018 May;6(5):379-388. doi: 10.1016/S2213-2600(18)30052-3. Epub 2018 Feb 26.


In vitro and in vivo pharmacodynamics of three novel antileishmanial lead series.

Van den Kerkhof M, Mabille D, Chatelain E, Mowbray CE, Braillard S, Hendrickx S, Maes L, Caljon G.

Int J Parasitol Drugs Drug Resist. 2018 Apr;8(1):81-86. doi: 10.1016/j.ijpddr.2018.01.006. Epub 2018 Jan 31.


Clinical applicability of and changes in perfusion MR imaging in brain metastases after stereotactic radiotherapy.

Kerkhof M, Ganeff I, Wiggenraad RGJ, Lycklama À Nijeholt GJ, Hammer S, Taphoorn MJB, Dirven L, Vos MJ.

J Neurooncol. 2018 May;138(1):133-139. doi: 10.1007/s11060-018-2779-7. Epub 2018 Feb 1.


Histologic Factors Associated With Need for Surgery in Patients With Pedunculated T1 Colorectal Carcinomas.

Backes Y, Elias SG, Groen JN, Schwartz MP, Wolfhagen FHJ, Geesing JMJ, Ter Borg F, van Bergeijk J, Spanier BWM, de Vos Tot Nederveen Cappel WH, Kessels K, Seldenrijk CA, Raicu MG, Drillenburg P, Milne AN, Kerkhof M, Seerden TCJ, Siersema PD, Vleggaar FP, Offerhaus GJA, Lacle MM, Moons LMG; Dutch T1 CRC Working Group.

Gastroenterology. 2018 May;154(6):1647-1659. doi: 10.1053/j.gastro.2018.01.023. Epub 2018 Jan 31.


Evaluation of a Pan-Leishmania Spliced-Leader RNA Detection Method in Human Blood and Experimentally Infected Syrian Golden Hamsters.

Eberhardt E, Van den Kerkhof M, Bulté D, Mabille D, Van Bockstal L, Monnerat S, Alves F, Mbui J, Delputte P, Cos P, Hendrickx S, Maes L, Caljon G.

J Mol Diagn. 2018 Mar;20(2):253-263. doi: 10.1016/j.jmoldx.2017.12.003. Epub 2018 Jan 31.


The effect of smoking on exacerbation risk in eosinophilic patients with COPD.

Kerkhof M, Hillyer EV, Price DB; all authors.

Eur Respir J. 2017 Dec 21;50(6). pii: 1702086. doi: 10.1183/13993003.02086-2017. Print 2017 Dec. No abstract available.


Management of post-midurethral sling voiding dysfunction. International Urogynecological Association research and development committee opinion.

Bazi T, Kerkhof MH, Takahashi SI, Abdel-Fattah M; IUGA Research and Development Committee.

Int Urogynecol J. 2018 Jan;29(1):23-28. doi: 10.1007/s00192-017-3509-y. Epub 2017 Nov 23.


Visual inspection of MR relative cerebral blood volume maps has limited value for distinguishing progression from pseudoprogression in glioblastoma multiforme patients.

Kerkhof M, Tans PL, Hagenbeek RE, Lycklama À Nijeholt GJ, Holla FK, Postma TJ, Straathof CS, Dirven L, Taphoorn MJ, Vos MJ.

CNS Oncol. 2017 Oct;6(4):297-306. doi: 10.2217/cns-2017-0013. Epub 2017 Oct 6.


Healthcare resource use and costs of severe, uncontrolled eosinophilic asthma in the UK general population.

Kerkhof M, Tran TN, Soriano JB, Golam S, Gibson D, Hillyer EV, Price DB.

Thorax. 2018 Feb;73(2):116-124. doi: 10.1136/thoraxjnl-2017-210531. Epub 2017 Sep 16.


Colorectal endoscopic full-thickness resection using a novel, flat-base over-the-scope clip: a prospective study.

Backes Y, Kappelle WFW, Berk L, Koch AD, Groen JN, de Vos Tot Nederveen Cappel WH, Schwartz MP, Kerkhof M, Siersema PD, Schröder R, Tan TG, Lacle MM, Vleggaar FP, Moons LMG; T1 CRC Working Group.

Endoscopy. 2017 Nov;49(11):1092-1097. doi: 10.1055/s-0043-114730. Epub 2017 Jul 28.


Blood eosinophil count and exacerbation risk in patients with COPD.

Kerkhof M, Sonnappa S, Postma DS, Brusselle G, Agustí A, Anzueto A, Jones R, Papi A, Pavord I, Pizzichini E, Popov T, Roche N, Ryan D, Thomas M, Vogelmeier C, Chisholm A, Freeman D, Bafadhel M, Hillyer EV, Price DB.

Eur Respir J. 2017 Jul 20;50(1). pii: 1700761. doi: 10.1183/13993003.00761-2017. Print 2017 Jul. No abstract available.


The prognostic value of lymph node yield in the earliest stage of colorectal cancer: a multicenter cohort study.

Backes Y, Elias SG, Bhoelan BS, Groen JN, van Bergeijk J, Seerden TCJ, Pullens HJM, Spanier BWM, Geesing JMJ, Kessels K, Kerkhof M, Siersema PD, de Vos Tot Nederveen Cappel WH, van Lelyveld N, Wolfhagen FHJ, Ter Borg F, Offerhaus GJA, Lacle MM, Moons LMG; Dutch T1 CRC Working Group.

BMC Med. 2017 Jul 14;15(1):129. doi: 10.1186/s12916-017-0892-7.


Obesity and pelvic organ prolapse.

Lee UJ, Kerkhof MH, van Leijsen SA, Heesakkers JP.

Curr Opin Urol. 2017 Sep;27(5):428-434. doi: 10.1097/MOU.0000000000000428. Review.


Combined treatment of miltefosine and paromomycin delays the onset of experimental drug resistance in Leishmania infantum.

Hendrickx S, Van den Kerkhof M, Mabille D, Cos P, Delputte P, Maes L, Caljon G.

PLoS Negl Trop Dis. 2017 May 15;11(5):e0005620. doi: 10.1371/journal.pntd.0005620. eCollection 2017 May.


Risk for Incomplete Resection after Macroscopic Radical Endoscopic Resection of T1 Colorectal Cancer: A Multicenter Cohort Study.

Backes Y, de Vos Tot Nederveen Cappel WH, van Bergeijk J, Ter Borg F, Schwartz MP, Spanier BWM, Geesing JMJ, Kessels K, Kerkhof M, Groen JN, Wolfhagen FHJ, Seerden TCJ, van Lelyveld N, Offerhaus GJA, Siersema PD, Lacle MM, Moons LMG.

Am J Gastroenterol. 2017 May;112(5):785-796. doi: 10.1038/ajg.2017.58. Epub 2017 Mar 21.


ARIA 2016: Care pathways implementing emerging technologies for predictive medicine in rhinitis and asthma across the life cycle.

Bousquet J, Hellings PW, Agache I, Bedbrook A, Bachert C, Bergmann KC, Bewick M, Bindslev-Jensen C, Bosnic-Anticevitch S, Bucca C, Caimmi DP, Camargos PA, Canonica GW, Casale T, Chavannes NH, Cruz AA, De Carlo G, Dahl R, Demoly P, Devillier P, Fonseca J, Fokkens WJ, Guldemond NA, Haahtela T, Illario M, Just J, Keil T, Klimek L, Kuna P, Larenas-Linnemann D, Morais-Almeida M, Mullol J, Murray R, Naclerio R, O'Hehir RE, Papadopoulos NG, Pawankar R, Potter P, Ryan D, Samolinski B, Schunemann HJ, Sheikh A, Simons FE, Stellato C, Todo-Bom A, Tomazic PV, Valiulis A, Valovirta E, Ventura MT, Wickman M, Young I, Yorgancioglu A, Zuberbier T, Aberer W, Akdis CA, Akdis M, Annesi-Maesano I, Ankri J, Ansotegui IJ, Anto JM, Arnavielhe S, Asarnoj A, Arshad H, Avolio F, Baiardini I, Barbara C, Barbagallo M, Bateman ED, Beghé B, Bel EH, Bennoor KS, Benson M, Białoszewski AZ, Bieber T, Bjermer L, Blain H, Blasi F, Boner AL, Bonini M, Bonini S, Bosse I, Bouchard J, Boulet LP, Bourret R, Bousquet PJ, Braido F, Briggs AH, Brightling CE, Brozek J, Buhl R, Bunu C, Burte E, Bush A, Caballero-Fonseca F, Calderon MA, Camuzat T, Cardona V, Carreiro-Martins P, Carriazo AM, Carlsen KH, Carr W, Cepeda Sarabia AM, Cesari M, Chatzi L, Chiron R, Chivato T, Chkhartishvili E, Chuchalin AG, Chung KF, Ciprandi G, de Sousa JC, Cox L, Crooks G, Custovic A, Dahlen SE, Darsow U, Dedeu T, Deleanu D, Denburg JA, De Vries G, Didier A, Dinh-Xuan AT, Dokic D, Douagui H, Dray G, Dubakiene R, Durham SR, Du Toit G, Dykewicz MS, Eklund P, El-Gamal Y, Ellers E, Emuzyte R, Farrell J, Fink Wagner A, Fiocchi A, Fletcher M, Forastiere F, Gaga M, Gamkrelidze A, Gemicioğlu B, Gereda JE, van Wick RG, González Diaz S, Grisle I, Grouse L, Gutter Z, Guzmán MA, Hellquist-Dahl B, Heinrich J, Horak F, Hourihane JO, Humbert M, Hyland M, Iaccarino G, Jares EJ, Jeandel C, Johnston SL, Joos G, Jonquet O, Jung KS, Jutel M, Kaidashev I, Khaitov M, Kalayci O, Kalyoncu AF, Kardas P, Keith PK, Kerkhof M, Kerstjens HA, Khaltaev N, Kogevinas M, Kolek V, Koppelman GH, Kowalski ML, Kuitunen M, Kull I, Kvedariene V, Lambrecht B, Lau S, Laune D, Le LT, Lieberman P, Lipworth B, Li J, Lodrup Carlsen KC, Louis R, Lupinek C, MacNee W, Magar Y, Magnan A, Mahboub B, Maier D, Majer I, Malva J, Manning P, De Manuel Keenoy E, Marshall GD, Masjedi MR, Mathieu-Dupas E, Maurer M, Mavale-Manuel S, Melén E, Melo-Gomes E, Meltzer EO, Mercier J, Merk H, Miculinic N, Mihaltan F, Milenkovic B, Millot-Keurinck J, Mohammad Y, Momas I, Mösges R, Muraro A, Namazova-Baranova L, Nadif R, Neffen H, Nekam K, Nieto A, Niggemann B, Nogueira-Silva L, Nogues M, Nyembue TD, Ohta K, Okamoto Y, Okubo K, Olive-Elias M, Ouedraogo S, Paggiaro P, Pali-Schöll I, Palkonen S, Panzner P, Papi A, Park HS, Passalacqua G, Pedersen S, Pereira AM, Pfaar O, Picard R, Pigearias B, Pin I, Plavec D, Pohl W, Popov TA, Portejoie F, Postma D, Poulsen LK, Price D, Rabe KF, Raciborski F, Roberts G, Robalo-Cordeiro C, Rodenas F, Rodriguez-Mañas L, Rolland C, Roman Rodriguez M, Romano A, Rosado-Pinto J, Rosario N, Rottem M, Sanchez-Borges M, Sastre-Dominguez J, Scadding GK, Scichilone N, Schmid-Grendelmeier P, Serrano E, Shields M, Siroux V, Sisul JC, Skrindo I, Smit HA, Solé D, Sooronbaev T, Spranger O, Stelmach R, Sterk PJ, Strandberg T, Sunyer J, Thijs C, Triggiani M, Valenta R, Valero A, van Eerd M, van Ganse E, van Hague M, Vandenplas O, Varona LL, Vellas B, Vezzani G, Vazankari T, Viegi G, Vontetsianos T, Wagenmann M, Walker S, Wang DY, Wahn U, Werfel T, Whalley B, Williams DM, Williams S, Wilson N, Wright J, Yawn BP, Yiallouros PK, Yusuf OM, Zaidi A, Zar HJ, Zernotti ME, Zhang L, Zhong N, Zidarn M.

Clin Transl Allergy. 2016 Dec 30;6:47. doi: 10.1186/s13601-016-0137-4. eCollection 2016. Review. Erratum in: Clin Transl Allergy. 2019 Oct 10;9:53.


Identifying Risk of Future Asthma Attacks Using UK Medical Record Data: A Respiratory Effectiveness Group Initiative.

Blakey JD, Price DB, Pizzichini E, Popov TA, Dimitrov BD, Postma DS, Josephs LK, Kaplan A, Papi A, Kerkhof M, Hillyer EV, Chisholm A, Thomas M.

J Allergy Clin Immunol Pract. 2017 Jul - Aug;5(4):1015-1024.e8. doi: 10.1016/j.jaip.2016.11.007. Epub 2016 Dec 22.


Impact of early- and late-onset preeclampsia on features of placental and newborn vascular health.

Herzog EM, Eggink AJ, Reijnierse A, Kerkhof MA, de Krijger RR, Roks AJ, Reiss IK, Nigg AL, Eilers PH, Steegers EA, Steegers-Theunissen RP.

Placenta. 2017 Jan;49:72-79. doi: 10.1016/j.placenta.2016.11.014. Epub 2016 Nov 27.


Endoscopic resection of high-risk T1 colorectal carcinoma prior to surgical resection has no adverse effect on long-term outcomes.

Overwater A, Kessels K, Elias SG, Backes Y, Spanier BWM, Seerden TCJ, Pullens HJM, de Vos Tot Nederveen Cappel WH, van den Blink A, Offerhaus GJA, van Bergeijk J, Kerkhof M, Geesing JMJ, Groen JN, van Lelyveld N, Ter Borg F, Wolfhagen F, Siersema PD, Lacle MM, Moons LMG; Dutch T1 CRC Working Group.

Gut. 2018 Feb;67(2):284-290. doi: 10.1136/gutjnl-2015-310961. Epub 2016 Nov 3.


Diagnosis of T1 colorectal cancer in pedunculated polyps in daily clinical practice: a multicenter study.

Backes Y, Moons LM, Novelli MR, van Bergeijk JD, Groen JN, Seerden TC, Schwartz MP, de Vos Tot Nederveen Cappel WH, Spanier BW, Geesing JM, Kessels K, Kerkhof M, Siersema PD, Offerhaus GJ, Milne AN, Lacle MM.

Mod Pathol. 2017 Jan;30(1):104-112. doi: 10.1038/modpathol.2016.165. Epub 2016 Oct 7.


In vitro 'time-to-kill' assay to assess the cidal activity dynamics of current reference drugs against Leishmania donovani and Leishmania infantum.

Maes L, Beyers J, Mondelaers A, Van den Kerkhof M, Eberhardt E, Caljon G, Hendrickx S.

J Antimicrob Chemother. 2017 Feb;72(2):428-430. doi: 10.1093/jac/dkw409. Epub 2016 Oct 5.


Eligibility of real-life patients with COPD for inclusion in trials of inhaled long-acting bronchodilator therapy.

Halpin DM, Kerkhof M, Soriano JB, Mikkelsen H, Price DB.

Respir Res. 2016 Sep 23;17(1):120.


Combining genomewide association study and lung eQTL analysis provides evidence for novel genes associated with asthma.

Nieuwenhuis MA, Siedlinski M, van den Berge M, Granell R, Li X, Niens M, van der Vlies P, Altmüller J, Nürnberg P, Kerkhof M, van Schayck OC, Riemersma RA, van der Molen T, de Monchy JG, Bossé Y, Sandford A, Bruijnzeel-Koomen CA, Gerth van Wijk R, Ten Hacken NH, Timens W, Boezen HM, Henderson J, Kabesch M, Vonk JM, Postma DS, Koppelman GH.

Allergy. 2016 Dec;71(12):1712-1720. doi: 10.1111/all.12990. Epub 2016 Aug 22.


Interobserver variability in the radiological assessment of magnetic resonance imaging (MRI) including perfusion MRI in glioblastoma multiforme.

Kerkhof M, Hagenbeek RE, van der Kallen BF, Lycklama À Nijeholt GJ, Dirven L, Taphoorn MJ, Vos MJ.

Eur J Neurol. 2016 Oct;23(10):1528-33. doi: 10.1111/ene.13070. Epub 2016 Jul 18.


Molecular detection of infection homogeneity and impact of miltefosine treatment in a Syrian golden hamster model of Leishmania donovani and L. infantum visceral leishmaniasis.

Eberhardt E, Mondelaers A, Hendrickx S, Van den Kerkhof M, Maes L, Caljon G.

Parasitol Res. 2016 Oct;115(10):4061-70. doi: 10.1007/s00436-016-5179-y. Epub 2016 Jul 13.


Endoscopic mucosal resection (EMR) versus endoscopic submucosal dissection (ESD) for resection of large distal non-pedunculated colorectal adenomas (MATILDA-trial): rationale and design of a multicenter randomized clinical trial.

Backes Y, Moons LM, van Bergeijk JD, Berk L, Ter Borg F, Ter Borg PC, Elias SG, Geesing JM, Groen JN, Hadithi M, Hardwick JC, Kerkhof M, Mangen MJ, Straathof JW, Schröder R, Schwartz MP, Spanier BW, de Vos Tot Nederveen Cappel WH, Wolfhagen FH, Koch AD.

BMC Gastroenterol. 2016 May 26;16(1):56. doi: 10.1186/s12876-016-0468-6.


DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis.

Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese SE, Markunas CA, Richmond RC, Xu CJ, Küpers LK, Oh SS, Hoyo C, Gruzieva O, Söderhäll C, Salas LA, Baïz N, Zhang H, Lepeule J, Ruiz C, Ligthart S, Wang T, Taylor JA, Duijts L, Sharp GC, Jankipersadsing SA, Nilsen RM, Vaez A, Fallin MD, Hu D, Litonjua AA, Fuemmeler BF, Huen K, Kere J, Kull I, Munthe-Kaas MC, Gehring U, Bustamante M, Saurel-Coubizolles MJ, Quraishi BM, Ren J, Tost J, Gonzalez JR, Peters MJ, Håberg SE, Xu Z, van Meurs JB, Gaunt TR, Kerkhof M, Corpeleijn E, Feinberg AP, Eng C, Baccarelli AA, Benjamin Neelon SE, Bradman A, Merid SK, Bergström A, Herceg Z, Hernandez-Vargas H, Brunekreef B, Pinart M, Heude B, Ewart S, Yao J, Lemonnier N, Franco OH, Wu MC, Hofman A, McArdle W, Van der Vlies P, Falahi F, Gillman MW, Barcellos LF, Kumar A, Wickman M, Guerra S, Charles MA, Holloway J, Auffray C, Tiemeier HW, Smith GD, Postma D, Hivert MF, Eskenazi B, Vrijheid M, Arshad H, Antó JM, Dehghan A, Karmaus W, Annesi-Maesano I, Sunyer J, Ghantous A, Pershagen G, Holland N, Murphy SK, DeMeo DL, Burchard EG, Ladd-Acosta C, Snieder H, Nystad W, Koppelman GH, Relton CL, Jaddoe VW, Wilcox A, Melén E, London SJ.

Am J Hum Genet. 2016 Apr 7;98(4):680-96. doi: 10.1016/j.ajhg.2016.02.019. Epub 2016 Mar 31.


Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story: Mechanisms of the Development of ALLergy; EU FP7-CP-IP; Project No: 261357; 2010-2015.

Bousquet J, Anto JM, Akdis M, Auffray C, Keil T, Momas I, Postma DS, Valenta R, Wickman M, Cambon-Thomsen A, Haahtela T, Lambrecht BN, Lodrup Carlsen KC, Koppelman GH, Sunyer J, Zuberbier T, Annesi-Maesano I, Arno A, Bindslev-Jensen C, De Carlo G, Forastiere F, Heinrich J, Kowalski ML, Maier D, Melén E, Palkonen S, Smit HA, Standl M, Wright J, Asarnoj A, Benet M, Ballardini N, Garcia-Aymerich J, Gehring U, Guerra S, Hohman C, Kull I, Lupinek C, Pinart M, Skrindo I, Westman M, Smagghe D, Akdis C, Albang R, Anastasova V, Anderson N, Bachert C, Ballereau S, Ballester F, Basagana X, Bedbrook A, Bergstrom A, von Berg A, Brunekreef B, Burte E, Carlsen KH, Chatzi L, Coquet JM, Curin M, Demoly P, Eller E, Fantini MP, Gerhard B, Hammad H, von Hertzen L, Hovland V, Jacquemin B, Just J, Keller T, Kerkhof M, Kiss R, Kogevinas M, Koletzko S, Lau S, Lehmann I, Lemonnier N, McEachan R, Mäkelä M, Mestres J, Minina E, Mowinckel P, Nadif R, Nawijn M, Oddie S, Pellet J, Pin I, Porta D, Rancière F, Rial-Sebbag A, Saeys Y, Schuijs MJ, Siroux V, Tischer CG, Torrent M, Varraso R, De Vocht J, Wenger K, Wieser S, Xu C.

Allergy. 2016 Nov;71(11):1513-1525. doi: 10.1111/all.12880. Epub 2016 Aug 23. Review.


Vaginal Fibroblastic Cells from Women with Pelvic Organ Prolapse Produce Matrices with Increased Stiffness and Collagen Content.

Ruiz-Zapata AM, Kerkhof MH, Ghazanfari S, Zandieh-Doulabi B, Stoop R, Smit TH, Helder MN.

Sci Rep. 2016 Mar 11;6:22971. doi: 10.1038/srep22971.


Toward a new generation of pelvic floor implants with electrospun nanofibrous matrices: A feasibility study.

Vashaghian M, Ruiz-Zapata AM, Kerkhof MH, Zandieh-Doulabi B, Werner A, Roovers JP, Smit TH.

Neurourol Urodyn. 2017 Mar;36(3):565-573. doi: 10.1002/nau.22969. Epub 2016 Feb 3.


Inhaled corticosteroid dose-response on blood eosinophils in asthma - Authors' reply.

Price DB, Pavord ID, Thomas M, Corrigan CJ, Wilson AM, Hillyer EV, Kerkhof M.

Lancet Respir Med. 2016 Jan;4(1):e1-e2. doi: 10.1016/S2213-2600(15)00506-8. No abstract available.


Predicting frequent COPD exacerbations using primary care data.

Kerkhof M, Freeman D, Jones R, Chisholm A, Price DB; Respiratory Effectiveness Group.

Int J Chron Obstruct Pulmon Dis. 2015 Nov 9;10:2439-50. doi: 10.2147/COPD.S94259. eCollection 2015. Erratum in: Int J Chron Obstruct Pulmon Dis. 2018 Aug 15;13:2471.


Meta-analysis identifies seven susceptibility loci involved in the atopic march.

Marenholz I, Esparza-Gordillo J, Rüschendorf F, Bauerfeind A, Strachan DP, Spycher BD, Baurecht H, Margaritte-Jeannin P, Sääf A, Kerkhof M, Ege M, Baltic S, Matheson MC, Li J, Michel S, Ang WQ, McArdle W, Arnold A, Homuth G, Demenais F, Bouzigon E, Söderhäll C, Pershagen G, de Jongste JC, Postma DS, Braun-Fahrländer C, Horak E, Ogorodova LM, Puzyrev VP, Bragina EY, Hudson TJ, Morin C, Duffy DL, Marks GB, Robertson CF, Montgomery GW, Musk B, Thompson PJ, Martin NG, James A, Sleiman P, Toskala E, Rodriguez E, Fölster-Holst R, Franke A, Lieb W, Gieger C, Heinzmann A, Rietschel E, Keil T, Cichon S, Nöthen MM, Pennell CE, Sly PD, Schmidt CO, Matanovic A, Schneider V, Heinig M, Hübner N, Holt PG, Lau S, Kabesch M, Weidinger S, Hakonarson H, Ferreira MAR, Laprise C, Freidin MB, Genuneit J, Koppelman GH, Melén E, Dizier MH, Henderson AJ, Lee YA.

Nat Commun. 2015 Nov 6;6:8804. doi: 10.1038/ncomms9804.


Blood eosinophil count and prospective annual asthma disease burden: a UK cohort study.

Price DB, Rigazio A, Campbell JD, Bleecker ER, Corrigan CJ, Thomas M, Wenzel SE, Wilson AM, Small MB, Gopalan G, Ashton VL, Burden A, Hillyer EV, Kerkhof M, Pavord ID.

Lancet Respir Med. 2015 Nov;3(11):849-58. doi: 10.1016/S2213-2600(15)00367-7. Epub 2015 Oct 19.


Seizures in oligodendroglial tumors.

Kerkhof M, Benit C, Duran-Pena A, Vecht CJ.

CNS Oncol. 2015;4(5):347-56. doi: 10.2217/cns.15.29. Epub 2015 Oct 19. Review.

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