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Items: 22


Tetracyclines as Inhibitors of Pre-microRNA Maturation: A Disconnection between RNA Binding and Inhibition.

Garner AL, Lorenz DA, Sandoval J, Gallagher EE, Kerk SA, Kaur T, Menon A.

ACS Med Chem Lett. 2019 Apr 22;10(5):816-821. doi: 10.1021/acsmedchemlett.9b00091. eCollection 2019 May 9.


Ablation of Cancer Stem Cells by Therapeutic Inhibition of the MDM2-p53 Interaction in Mucoepidermoid Carcinoma.

Andrews A, Warner K, Rodriguez-Ramirez C, Pearson AT, Nör F, Zhang Z, Kerk S, Kulkarni A, Helman JI, Brenner JC, Wicha MS, Wang S, Nör JE.

Clin Cancer Res. 2019 Mar 1;25(5):1588-1600. doi: 10.1158/1078-0432.CCR-17-2730. Epub 2018 Nov 29.


Bacteria Display Differential Growth and Adhesion Characteristics on Human Hair Shafts.

Kerk SK, Lai HY, Sze SK, Ng KW, Schmidtchen A, Adav SS.

Front Microbiol. 2018 Sep 7;9:2145. doi: 10.3389/fmicb.2018.02145. eCollection 2018.


Expansion of cat-ELCCA for the Discovery of Small Molecule Inhibitors of the Pre-let-7-Lin28 RNA-Protein Interaction.

Lorenz DA, Kaur T, Kerk SA, Gallagher EE, Sandoval J, Garner AL.

ACS Med Chem Lett. 2018 May 16;9(6):517-521. doi: 10.1021/acsmedchemlett.8b00126. eCollection 2018 Jun 14.


Identification of Antibacterial Components in Human Hair Shafts.

Subbaiah RS, Kerk SK, Lian Y, Lunny D, Sze SK, Ng KW, Schmidtchen A, Adav SS.

Acta Derm Venereol. 2018 Jul 11;98(7):708-710. doi: 10.2340/00015555-2952. No abstract available.


Menin regulates the serine biosynthetic pathway in Ewing sarcoma.

Svoboda LK, Teh SSK, Sud S, Kerk S, Zebolsky A, Treichel S, Thomas D, Halbrook CJ, Lee HJ, Kremer D, Zhang L, Klossowski S, Bankhead AR, Magnuson B, Ljungman M, Cierpicki T, Grembecka J, Lyssiotis CA, Lawlor ER.

J Pathol. 2018 Jul;245(3):324-336. doi: 10.1002/path.5085. Epub 2018 May 28.


Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins.

Adav SS, Subbaiaih RS, Kerk SK, Lee AY, Lai HY, Ng KW, Sze SK, Schmidtchen A.

Sci Rep. 2018 Jan 25;8(1):1599. doi: 10.1038/s41598-018-20041-9.


An intersectional gene regulatory strategy defines subclass diversity of C. elegans motor neurons.

Kratsios P, Kerk SY, Catela C, Liang J, Vidal B, Bayer EA, Feng W, De La Cruz ED, Croci L, Consalez GG, Mizumoto K, Hobert O.

Elife. 2017 Jul 5;6. pii: e25751. doi: 10.7554/eLife.25751.


BET bromodomain inhibitor (JQ1) and tumor angiogenesis.

Bid HK, Kerk S.

Oncoscience. 2016 Nov 23;3(11-12):316-317. doi: 10.18632/oncoscience.326. eCollection 2016. No abstract available.


Diversification of C. elegans Motor Neuron Identity via Selective Effector Gene Repression.

Kerk SY, Kratsios P, Hart M, Mourao R, Hobert O.

Neuron. 2017 Jan 4;93(1):80-98. doi: 10.1016/j.neuron.2016.11.036.


5T4-Targeted Therapy Ablates Cancer Stem Cells and Prevents Recurrence of Head and Neck Squamous Cell Carcinoma.

Kerk SA, Finkel KA, Pearson AT, Warner KA, Zhang Z, Nör F, Wagner VP, Vargas PA, Wicha MS, Hurt EM, Hollingsworth RE, Tice DA, Nör JE.

Clin Cancer Res. 2017 May 15;23(10):2516-2527. doi: 10.1158/1078-0432.CCR-16-1834. Epub 2016 Oct 25.


Therapeutic Inhibition of the MDM2-p53 Interaction Prevents Recurrence of Adenoid Cystic Carcinomas.

Nör F, Warner KA, Zhang Z, Acasigua GA, Pearson AT, Kerk SA, Helman JI, Sant'Ana Filho M, Wang S, Nör JE.

Clin Cancer Res. 2017 Feb 15;23(4):1036-1048. doi: 10.1158/1078-0432.CCR-16-1235. Epub 2016 Aug 22.


IL-6 Inhibition With MEDI5117 Decreases The Fraction of Head and Neck Cancer Stem Cells and Prevents Tumor Recurrence.

Finkel KA, Warner KA, Kerk S, Bradford CR, McLean SA, Prince ME, Zhong H, Hurt EM, Hollingsworth RE, Wicha MS, Tice DA, Nör JE.

Neoplasia. 2016 May;18(5):273-281. doi: 10.1016/j.neo.2016.03.004. Epub 2016 Apr 15.


Transcriptional coordination of synaptogenesis and neurotransmitter signaling.

Kratsios P, Pinan-Lucarré B, Kerk SY, Weinreb A, Bessereau JL, Hobert O.

Curr Biol. 2015 May 18;25(10):1282-95. doi: 10.1016/j.cub.2015.03.028. Epub 2015 Apr 23.


Starvation-induced transgenerational inheritance of small RNAs in C. elegans.

Rechavi O, Houri-Ze'evi L, Anava S, Goh WSS, Kerk SY, Hannon GJ, Hobert O.

Cell. 2014 Jul 17;158(2):277-287. doi: 10.1016/j.cell.2014.06.020. Epub 2014 Jul 10.


Osthole activates glucose uptake but blocks full activation in L929 fibroblast cells, and inhibits uptake in HCLE cells.

Alabi OD, Gunnink SM, Kuiper BD, Kerk SA, Braun E, Louters LL.

Life Sci. 2014 May 2;102(2):105-10. doi: 10.1016/j.lfs.2014.03.017. Epub 2014 Mar 21.


Alkaline pH activates the transport activity of GLUT1 in L929 fibroblast cells.

Gunnink SM, Kerk SA, Kuiper BD, Alabi OD, Kuipers DP, Praamsma RC, Wrobel KE, Louters LL.

Biochimie. 2014 Apr;99:189-94. doi: 10.1016/j.biochi.2013.12.003. Epub 2013 Dec 12.


Ancient vertebrate conserved noncoding elements have been evolving rapidly in teleost fishes.

Lee AP, Kerk SY, Tan YY, Brenner S, Venkatesh B.

Mol Biol Evol. 2011 Mar;28(3):1205-15. doi: 10.1093/molbev/msq304. Epub 2010 Nov 15.


Baxbeta: a constitutively active human Bax isoform that is under tight regulatory control by the proteasomal degradation mechanism.

Fu NY, Sukumaran SK, Kerk SY, Yu VC.

Mol Cell. 2009 Jan 16;33(1):15-29. doi: 10.1016/j.molcel.2008.11.025.


Dopamine auto-oxidation aggravates non-apoptotic cell death induced by over-expression of human A53T mutant alpha-synuclein in dopaminergic PC12 cells.

Zhou ZD, Kerk SY, Xiong GG, Lim TM.

J Neurochem. 2009 Feb;108(3):601-10. doi: 10.1111/j.1471-4159.2008.05795.x. Epub 2008 Nov 27.


Endogenous dopamine (DA) renders dopaminergic cells vulnerable to challenge of proteasome inhibitor MG132.

Zhou Z, Kerk S, Meng Lim T.

Free Radic Res. 2008 May;42(5):456-66. doi: 10.1080/10715760802005177.


No major effect of orciprenaline and propranolol upon ACTH-induced cortisol secretion.

Nonell A, Kerk S, Lederbogen F, Kopf D, Hamann B, Lewicka S, Deuschle M.

Exp Clin Endocrinol Diabetes. 2004 Jan;112(1):59-61.


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