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Items: 1 to 50 of 264

1.

Lymphangiogenesis in a mouse model of renal transplant rejection extends life span of the recipients.

Pedersen MS, Müller M, Rülicke T, Leitner N, Kain R, Regele H, Wang S, Gröne HJ, Rong S, Haller H, Gueler F, Rees AJ, Kerjaschki D.

Kidney Int. 2019 Sep 3. pii: S0085-2538(19)30843-9. doi: 10.1016/j.kint.2019.07.027. [Epub ahead of print]

PMID:
31718844
2.

Generation of blood vessel organoids from human pluripotent stem cells.

Wimmer RA, Leopoldi A, Aichinger M, Kerjaschki D, Penninger JM.

Nat Protoc. 2019 Nov;14(11):3082-3100. doi: 10.1038/s41596-019-0213-z. Epub 2019 Sep 25.

PMID:
31554955
3.

Human blood vessel organoids as a model of diabetic vasculopathy.

Wimmer RA, Leopoldi A, Aichinger M, Wick N, Hantusch B, Novatchkova M, Taubenschmid J, Hämmerle M, Esk C, Bagley JA, Lindenhofer D, Chen G, Boehm M, Agu CA, Yang F, Fu B, Zuber J, Knoblich JA, Kerjaschki D, Penninger JM.

Nature. 2019 Jan;565(7740):505-510. doi: 10.1038/s41586-018-0858-8. Epub 2019 Jan 16.

PMID:
30651639
4.

ARP3 Controls the Podocyte Architecture at the Kidney Filtration Barrier.

Schell C, Sabass B, Helmstaedter M, Geist F, Abed A, Yasuda-Yamahara M, Sigle A, Maier JI, Grahammer F, Siegerist F, Artelt N, Endlich N, Kerjaschki D, Arnold HH, Dengjel J, Rogg M, Huber TB.

Dev Cell. 2018 Dec 17;47(6):741-757.e8. doi: 10.1016/j.devcel.2018.11.011. Epub 2018 Nov 29.

5.

Expression of 15-lipoxygenase-1 in Merkel cell carcinoma is linked to advanced disease.

Fochtmann-Frana A, Haymerle G, Schachner H, Pammer J, Loewe R, Kerjaschki D, Perisanidis C, Erovic BM.

Clin Otolaryngol. 2018 Oct;43(5):1335-1344. doi: 10.1111/coa.13191. Epub 2018 Jul 30.

PMID:
29992788
6.

Breast cancer metastasis through the lympho-vascular system.

Nathanson SD, Krag D, Kuerer HM, Newman LA, Brown M, Kerjaschki D, Pereira ER, Padera TP.

Clin Exp Metastasis. 2018 Aug;35(5-6):443-454. doi: 10.1007/s10585-018-9902-1. Epub 2018 May 23. Review.

PMID:
29796854
7.

Lymphatic exosomes promote dendritic cell migration along guidance cues.

Brown M, Johnson LA, Leone DA, Majek P, Vaahtomeri K, Senfter D, Bukosza N, Schachner H, Asfour G, Langer B, Hauschild R, Parapatics K, Hong YK, Bennett KL, Kain R, Detmar M, Sixt M, Jackson DG, Kerjaschki D.

J Cell Biol. 2018 Jun 4;217(6):2205-2221. doi: 10.1083/jcb.201612051. Epub 2018 Apr 12.

8.

Lymph node blood vessels provide exit routes for metastatic tumor cell dissemination in mice.

Brown M, Assen FP, Leithner A, Abe J, Schachner H, Asfour G, Bago-Horvath Z, Stein JV, Uhrin P, Sixt M, Kerjaschki D.

Science. 2018 Mar 23;359(6382):1408-1411. doi: 10.1126/science.aal3662.

PMID:
29567714
9.

2015 Homer W. Smith Award: The Podocyte from Periphery to Center Stage.

Kerjaschki D.

J Am Soc Nephrol. 2016 Nov;27(11):3266-3270. Epub 2016 Jun 20. Review.

10.

Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions.

Martins R, Maier J, Gorki AD, Huber KV, Sharif O, Starkl P, Saluzzo S, Quattrone F, Gawish R, Lakovits K, Aichinger MC, Radic-Sarikas B, Lardeau CH, Hladik A, Korosec A, Brown M, Vaahtomeri K, Duggan M, Kerjaschki D, Esterbauer H, Colinge J, Eisenbarth SC, Decker T, Bennett KL, Kubicek S, Sixt M, Superti-Furga G, Knapp S.

Nat Immunol. 2016 Dec;17(12):1361-1372. doi: 10.1038/ni.3590. Epub 2016 Oct 31.

PMID:
27798618
11.

Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes.

Leithner A, Eichner A, Müller J, Reversat A, Brown M, Schwarz J, Merrin J, de Gorter DJ, Schur F, Bayerl J, de Vries I, Wieser S, Hauschild R, Lai FP, Moser M, Kerjaschki D, Rottner K, Small JV, Stradal TE, Sixt M.

Nat Cell Biol. 2016 Nov;18(11):1253-1259. doi: 10.1038/ncb3426. Epub 2016 Oct 24.

PMID:
27775702
12.

The brain-tumor related protein podoplanin regulates synaptic plasticity and hippocampus-dependent learning and memory.

Cicvaric A, Yang J, Krieger S, Khan D, Kim EJ, Dominguez-Rodriguez M, Cabatic M, Molz B, Acevedo Aguilar JP, Milicevic R, Smani T, Breuss JM, Kerjaschki D, Pollak DD, Uhrin P, Monje FJ.

Ann Med. 2016 Dec;48(8):652-668. Epub 2016 Aug 25.

13.

A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor Angiogenesis.

Kollmann K, Heller G, Schneckenleithner C, Warsch W, Scheicher R, Ott RG, Schäfer M, Fajmann S, Schlederer M, Schiefer AI, Reichart U, Mayerhofer M, Hoeller C, Zöchbauer-Müller S, Kerjaschki D, Bock C, Kenner L, Hoefler G, Freissmuth M, Green AR, Moriggl R, Busslinger M, Malumbres M, Sexl V.

Cancer Cell. 2016 Aug 8;30(2):359-360. doi: 10.1016/j.ccell.2016.07.003. Epub 2016 Aug 8. No abstract available.

14.

Blood capillary rarefaction and lymphatic capillary neoangiogenesis are key contributors to renal allograft fibrosis in an ACE inhibition rat model.

Hamar P, Kerjaschki D.

Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H981-H990. doi: 10.1152/ajpheart.00320.2016. Epub 2016 Aug 5.

15.

A flexible, multilayered protein scaffold maintains the slit in between glomerular podocytes.

Grahammer F, Wigge C, Schell C, Kretz O, Patrakka J, Schneider S, Klose M, Kind J, Arnold SJ, Habermann A, Bräuniger R, Rinschen MM, Völker L, Bregenzer A, Rubbenstroth D, Boerries M, Kerjaschki D, Miner JH, Walz G, Benzing T, Fornoni A, Frangakis AS, Huber TB.

JCI Insight. 2016 Jun 16;1(9). pii: 86177. doi: 10.1172/jci.insight.86177.

16.

Par3A is dispensable for the function of the glomerular filtration barrier of the kidney.

Koehler S, Tellkamp F, Niessen CM, Bloch W, Kerjaschki D, Schermer B, Benzing T, Brinkkoetter PT.

Am J Physiol Renal Physiol. 2016 Jul 1;311(1):F112-9. doi: 10.1152/ajprenal.00171.2016. Epub 2016 Apr 27.

17.

Prohibitin-2 Depletion Unravels Extra-Mitochondrial Functions at the Kidney Filtration Barrier.

Ising C, Bharill P, Brinkkoetter S, Brähler S, Schroeter C, Koehler S, Hagmann H, Merkwirth C, Höhne M, Müller RU, Fabretti F, Schermer B, Bloch W, Kerjaschki D, Kurschat CE, Benzing T, Brinkkoetter PT.

Am J Pathol. 2016 May;186(5):1128-39. doi: 10.1016/j.ajpath.2015.12.018.

PMID:
27105734
18.

Intralymphatic CCL21 Promotes Tissue Egress of Dendritic Cells through Afferent Lymphatic Vessels.

Russo E, Teijeira A, Vaahtomeri K, Willrodt AH, Bloch JS, Nitschké M, Santambrogio L, Kerjaschki D, Sixt M, Halin C.

Cell Rep. 2016 Feb 23;14(7):1723-1734. doi: 10.1016/j.celrep.2016.01.048. Epub 2016 Feb 11.

19.

Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine.

Valent P, Groner B, Schumacher U, Superti-Furga G, Busslinger M, Kralovics R, Zielinski C, Penninger JM, Kerjaschki D, Stingl G, Smolen JS, Valenta R, Lassmann H, Kovar H, Jäger U, Kornek G, Müller M, Sörgel F.

J Innate Immun. 2016;8(2):111-20. doi: 10.1159/000443526. Epub 2016 Feb 5.

20.

Residual urinary extracellular vesicles in ultracentrifugation supernatants after hydrostatic filtration dialysis enrichment.

Musante L, Tataruch-Weinert D, Kerjaschki D, Henry M, Meleady P, Holthofer H.

J Extracell Vesicles. 2016 Dec 23;6(1):1267896. doi: 10.1080/20013078.2016.1267896. eCollection 2017.

21.

Sufficient Evidence for Lymphatics in the Developing and Adult Human Choroid?

Heindl LM, Kaser-Eichberger A, Schlereth SL, Bock F, Regenfuss B, Reitsamer HA, McMenamin P, Lutty GA, Maruyama K, Chen L, Dana R, Kerjaschki D, Alitalo K, De Stefano ME, Junghans BM, Schroedl F, Cursiefen C.

Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6709-10. doi: 10.1167/iovs.15-17686. No abstract available.

22.

HANAC Syndrome Col4a1 Mutation Causes Neonate Glomerular Hyperpermeability and Adult Glomerulocystic Kidney Disease.

Chen Z, Migeon T, Verpont MC, Zaidan M, Sado Y, Kerjaschki D, Ronco P, Plaisier E.

J Am Soc Nephrol. 2016 Apr;27(4):1042-54. doi: 10.1681/ASN.2014121217. Epub 2015 Aug 10.

23.

Selection of scFv Antibody Fragments Binding to Human Blood versus Lymphatic Endothelial Surface Antigens by Direct Cell Phage Display.

Keller T, Kalt R, Raab I, Schachner H, Mayrhofer C, Kerjaschki D, Hantusch B.

PLoS One. 2015 May 20;10(5):e0127169. doi: 10.1371/journal.pone.0127169. eCollection 2015.

24.

The nitric oxide donor, S-nitroso human serum albumin, as an adjunct to HTK-N cardioplegia improves protection during cardioplegic arrest after myocardial infarction in rats.

Trescher K, Dzilic E, Kreibich M, Gasser H, Aumayr K, Kerjaschki D, Pelzmann B, Hallström S, Podesser BK.

Interact Cardiovasc Thorac Surg. 2015 Mar;20(3):387-94. doi: 10.1093/icvts/ivu383. Epub 2014 Dec 2.

PMID:
25468794
25.

Consensus statement on the immunohistochemical detection of ocular lymphatic vessels.

Schroedl F, Kaser-Eichberger A, Schlereth SL, Bock F, Regenfuss B, Reitsamer HA, Lutty GA, Maruyama K, Chen L, Lütjen-Drecoll E, Dana R, Kerjaschki D, Alitalo K, De Stefano ME, Junghans BM, Heindl LM, Cursiefen C.

Invest Ophthalmol Vis Sci. 2014 Oct 14;55(10):6440-2. doi: 10.1167/iovs.14-15638. Review.

26.

MicroRNA-193a Regulates the Transdifferentiation of Human Parietal Epithelial Cells toward a Podocyte Phenotype.

Kietzmann L, Guhr SS, Meyer TN, Ni L, Sachs M, Panzer U, Stahl RA, Saleem MA, Kerjaschki D, Gebeshuber CA, Meyer-Schwesinger C.

J Am Soc Nephrol. 2015 Jun;26(6):1389-401. doi: 10.1681/ASN.2014020190. Epub 2014 Sep 30.

27.

The effect of podoplanin inhibition on lymphangiogenesis under pathological conditions.

Maruyama Y, Maruyama K, Kato Y, Kajiya K, Moritoh S, Yamamoto K, Matsumoto Y, Sawane M, Kerjaschki D, Nakazawa T, Kinoshita S.

Invest Ophthalmol Vis Sci. 2014 Jul 1;55(8):4813-22. doi: 10.1167/iovs.13-13711.

PMID:
24985477
28.

mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress.

Grahammer F, Haenisch N, Steinhardt F, Sandner L, Roerden M, Arnold F, Cordts T, Wanner N, Reichardt W, Kerjaschki D, Ruegg MA, Hall MN, Moulin P, Busch H, Boerries M, Walz G, Artunc F, Huber TB.

Proc Natl Acad Sci U S A. 2014 Jul 8;111(27):E2817-26. doi: 10.1073/pnas.1402352111. Epub 2014 Jun 23. Erratum in: Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):E6826. Sander, Lukas [corrected to Sandner, Lukas].

29.

Reduction of proteinuria through podocyte alkalinization.

Altintas MM, Moriwaki K, Wei C, Möller CC, Flesche J, Li J, Yaddanapudi S, Faridi MH, Gödel M, Huber TB, Preston RA, Jiang JX, Kerjaschki D, Sever S, Reiser J.

J Biol Chem. 2014 Jun 20;289(25):17454-67. doi: 10.1074/jbc.M114.568998. Epub 2014 May 9.

30.

Nucleophilic cross-linked, dextran coated iron oxide nanoparticles as basis for molecular imaging: synthesis, characterization, visualization and comparison with previous product.

Borny R, Lechleitner T, Schmiedinger T, Hermann M, Tessadri R, Redhammer G, Neumüller J, Kerjaschki D, Berzaczy G, Erman G, Popovic M, Lammer J, Funovics M.

Contrast Media Mol Imaging. 2015 Jan-Feb;10(1):18-27. doi: 10.1002/cmmi.1595. Epub 2014 Apr 22.

PMID:
24753451
31.

Ezrin is down-regulated in diabetic kidney glomeruli and regulates actin reorganization and glucose uptake via GLUT1 in cultured podocytes.

Wasik AA, Koskelainen S, Hyvönen ME, Musante L, Lehtonen E, Koskenniemi K, Tienari J, Vaheri A, Kerjaschki D, Szalay C, Révész C, Varmanen P, Nyman TA, Hamar P, Holthöfer H, Lehtonen S.

Am J Pathol. 2014 Jun;184(6):1727-39. doi: 10.1016/j.ajpath.2014.03.002. Epub 2014 Apr 13.

PMID:
24726496
32.

IGFBP7, a novel tumor stroma marker, with growth-promoting effects in colon cancer through a paracrine tumor-stroma interaction.

Rupp C, Scherzer M, Rudisch A, Unger C, Haslinger C, Schweifer N, Artaker M, Nivarthi H, Moriggl R, Hengstschläger M, Kerjaschki D, Sommergruber W, Dolznig H, Garin-Chesa P.

Oncogene. 2015 Feb 12;34(7):815-25. doi: 10.1038/onc.2014.18. Epub 2014 Mar 17.

PMID:
24632618
33.

The lymphatic vasculature revisited.

Kerjaschki D.

J Clin Invest. 2014 Mar;124(3):874-7. doi: 10.1172/JCI74854. Epub 2014 Mar 3.

34.

In vivo imaging of kidney glomeruli transplanted into the anterior chamber of the mouse eye.

Kistler AD, Caicedo A, Abdulreda MH, Faul C, Kerjaschki D, Berggren PO, Reiser J, Fornoni A.

Sci Rep. 2014 Jan 27;4:3872. doi: 10.1038/srep03872.

35.

[Johann Heinrich Holzner : 03.12.1924--26.02.2013].

Kerjaschki D.

Pathologe. 2013 Nov;34 Suppl 2:316-7. doi: 10.1007/s00292-013-1873-z. German. No abstract available.

PMID:
24196644
36.

Transient receptor potential channel 6 (TRPC6) protects podocytes during complement-mediated glomerular disease.

Kistler AD, Singh G, Altintas MM, Yu H, Fernandez IC, Gu C, Wilson C, Srivastava SK, Dietrich A, Walz K, Kerjaschki D, Ruiz P, Dryer S, Sever S, Dinda AK, Faul C, Reiser J.

J Biol Chem. 2013 Dec 20;288(51):36598-609. doi: 10.1074/jbc.M113.488122. Epub 2013 Nov 5.

37.

Renopathological Microstructure Visualization from Formalin Fixed Kidney Tissue by Matrix-Assisted Laser/Desorption Ionization-Time-of-Flight Mass Spectrometry Imaging.

Fröhlich S, Putz B, Schachner H, Kerjaschki D, Allmaier G, Marchetti-Deschmann M.

Balkan J Med Genet. 2012 Dec;15(Suppl):13-6. doi: 10.2478/v10034-012-0012-0.

38.

A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis.

Kollmann K, Heller G, Schneckenleithner C, Warsch W, Scheicher R, Ott RG, Schäfer M, Fajmann S, Schlederer M, Schiefer AI, Reichart U, Mayerhofer M, Hoeller C, Zöchbauer-Müller S, Kerjaschki D, Bock C, Kenner L, Hoefler G, Freissmuth M, Green AR, Moriggl R, Busslinger M, Malumbres M, Sexl V.

Cancer Cell. 2013 Aug 12;24(2):167-81. doi: 10.1016/j.ccr.2013.07.012. Erratum in: Cancer Cell. 2016 Aug 8;30(2):359-360.

39.

Thymic medullar conduits-associated podoplanin promotes natural regulatory T cells.

Fuertbauer E, Zaujec J, Uhrin P, Raab I, Weber M, Schachner H, Bauer M, Schütz GJ, Binder BR, Sixt M, Kerjaschki D, Stockinger H.

Immunol Lett. 2013 Jul-Aug;154(1-2):31-41. doi: 10.1016/j.imlet.2013.07.007. Epub 2013 Jul 30.

PMID:
23912054
40.

Immune cells control skin lymphatic electrolyte homeostasis and blood pressure.

Wiig H, Schröder A, Neuhofer W, Jantsch J, Kopp C, Karlsen TV, Boschmann M, Goss J, Bry M, Rakova N, Dahlmann A, Brenner S, Tenstad O, Nurmi H, Mervaala E, Wagner H, Beck FX, Müller DN, Kerjaschki D, Luft FC, Harrison DG, Alitalo K, Titze J.

J Clin Invest. 2013 Jul;123(7):2803-15. doi: 10.1172/JCI60113. Epub 2013 Jun 3.

41.

Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1.

Gebeshuber CA, Kornauth C, Dong L, Sierig R, Seibler J, Reiss M, Tauber S, Bilban M, Wang S, Kain R, Böhmig GA, Moeller MJ, Gröne HJ, Englert C, Martinez J, Kerjaschki D.

Nat Med. 2013 Apr;19(4):481-7. doi: 10.1038/nm.3142. Epub 2013 Mar 17.

PMID:
23502960
42.

Vps34 deficiency reveals the importance of endocytosis for podocyte homeostasis.

Bechtel W, Helmstädter M, Balica J, Hartleben B, Kiefer B, Hrnjic F, Schell C, Kretz O, Liu S, Geist F, Kerjaschki D, Walz G, Huber TB.

J Am Soc Nephrol. 2013 Apr;24(5):727-43. doi: 10.1681/ASN.2012070700. Epub 2013 Mar 14.

43.

N-wasp is required for stabilization of podocyte foot processes.

Schell C, Baumhakl L, Salou S, Conzelmann AC, Meyer C, Helmstädter M, Wrede C, Grahammer F, Eimer S, Kerjaschki D, Walz G, Snapper S, Huber TB.

J Am Soc Nephrol. 2013 Apr;24(5):713-21. doi: 10.1681/ASN.2012080844. Epub 2013 Mar 7.

44.

Enhanced lymph vessel density, remodeling, and inflammation are reflected by gene expression signatures in dermal lymphatic endothelial cells in type 2 diabetes.

Haemmerle M, Keller T, Egger G, Schachner H, Steiner CW, Stokic D, Neumayer C, Brown MK, Kerjaschki D, Hantusch B.

Diabetes. 2013 Jul;62(7):2509-29. doi: 10.2337/db12-0844. Epub 2013 Feb 19.

45.

Is podocyte research at a tipping point? Report from the 9(th) International Podocyte Conference.

Schell CB, Kerjaschki D, Reiser J, Huber TB.

Kidney Int. 2012 Nov;82(10):1041-3. doi: 10.1038/ki.2012.319. No abstract available.

46.

Soluble FLT1 binds lipid microdomains in podocytes to control cell morphology and glomerular barrier function.

Jin J, Sison K, Li C, Tian R, Wnuk M, Sung HK, Jeansson M, Zhang C, Tucholska M, Jones N, Kerjaschki D, Shibuya M, Fantus IG, Nagy A, Gerber HP, Ferrara N, Pawson T, Quaggin SE.

Cell. 2012 Oct 12;151(2):384-99. doi: 10.1016/j.cell.2012.08.037.

47.

Type I interferons promote fatal immunopathology by regulating inflammatory monocytes and neutrophils during Candida infections.

Majer O, Bourgeois C, Zwolanek F, Lassnig C, Kerjaschki D, Mack M, Müller M, Kuchler K.

PLoS Pathog. 2012;8(7):e1002811. doi: 10.1371/journal.ppat.1002811. Epub 2012 Jul 26.

48.

Role of the polarity protein Scribble for podocyte differentiation and maintenance.

Hartleben B, Widmeier E, Wanner N, Schmidts M, Kim ST, Schneider L, Mayer B, Kerjaschki D, Miner JH, Walz G, Huber TB.

PLoS One. 2012;7(5):e36705. doi: 10.1371/journal.pone.0036705. Epub 2012 May 7. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/2c0c1c61-0627-4794-b6f2-01fc4db84dcb.

49.

Decentral gene expression analysis for ER+/Her2- breast cancer: results of a proficiency testing program for the EndoPredict assay.

Denkert C, Kronenwett R, Schlake W, Bohmann K, Penzel R, Weber KE, Höfler H, Lehmann U, Schirmacher P, Specht K, Rudas M, Kreipe HH, Schraml P, Schlake G, Bago-Horvath Z, Tiecke F, Varga Z, Moch H, Schmidt M, Prinzler J, Kerjaschki D, Sinn BV, Müller BM, Filipits M, Petry C, Dietel M.

Virchows Arch. 2012 Mar;460(3):251-9. doi: 10.1007/s00428-012-1204-4. Epub 2012 Feb 28.

50.

Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias.

Schneckenleithner C, Bago-Horvath Z, Dolznig H, Neugebauer N, Kollmann K, Kolbe T, Decker T, Kerjaschki D, Wagner KU, Müller M, Stoiber D, Sexl V.

Oncotarget. 2011 Dec;2(12):1043-54.

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