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Items: 24

1.

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner.

Jaitin DA, Adlung L, Thaiss CA, Weiner A, Li B, Descamps H, Lundgren P, Bleriot C, Liu Z, Deczkowska A, Keren-Shaul H, David E, Zmora N, Eldar SM, Lubezky N, Shibolet O, Hill DA, Lazar MA, Colonna M, Ginhoux F, Shapiro H, Elinav E, Amit I.

Cell. 2019 Jul 25;178(3):686-698.e14. doi: 10.1016/j.cell.2019.05.054. Epub 2019 Jun 27.

PMID:
31257031
2.

MARS-seq2.0: an experimental and analytical pipeline for indexed sorting combined with single-cell RNA sequencing.

Keren-Shaul H, Kenigsberg E, Jaitin DA, David E, Paul F, Tanay A, Amit I.

Nat Protoc. 2019 Jun;14(6):1841-1862. doi: 10.1038/s41596-019-0164-4. Epub 2019 May 17.

PMID:
31101904
3.

PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model.

Rosenzweig N, Dvir-Szternfeld R, Tsitsou-Kampeli A, Keren-Shaul H, Ben-Yehuda H, Weill-Raynal P, Cahalon L, Kertser A, Baruch K, Amit I, Weiner A, Schwartz M.

Nat Commun. 2019 Jan 28;10(1):465. doi: 10.1038/s41467-019-08352-5.

4.

Single cell dissection of plasma cell heterogeneity in symptomatic and asymptomatic myeloma.

Ledergor G, Weiner A, Zada M, Wang SY, Cohen YC, Gatt ME, Snir N, Magen H, Koren-Michowitz M, Herzog-Tzarfati K, Keren-Shaul H, Bornstein C, Rotkopf R, Yofe I, David E, Yellapantula V, Kay S, Salai M, Ben Yehuda D, Nagler A, Shvidel L, Orr-Urtreger A, Halpern KB, Itzkovitz S, Landgren O, San-Miguel J, Paiva B, Keats JJ, Papaemmanuil E, Avivi I, Barbash GI, Tanay A, Amit I.

Nat Med. 2018 Dec;24(12):1867-1876. doi: 10.1038/s41591-018-0269-2. Epub 2018 Dec 6.

PMID:
30523328
5.

Combining Developmental and Perturbation-Seq Uncovers Transcriptional Modules Orchestrating Neuronal Remodeling.

Alyagor I, Berkun V, Keren-Shaul H, Marmor-Kollet N, David E, Mayseless O, Issman-Zecharya N, Amit I, Schuldiner O.

Dev Cell. 2018 Oct 8;47(1):38-52.e6. doi: 10.1016/j.devcel.2018.09.013.

6.

The 'TranSeq' 3'-end sequencing method for high-throughput transcriptomics and gene space refinement in plant genomes.

Tzfadia O, Bocobza S, Defoort J, Almekias-Siegl E, Panda S, Levy M, Storme V, Rombauts S, Jaitin DA, Keren-Shaul H, Van de Peer Y, Aharoni A.

Plant J. 2018 Oct;96(1):223-232. doi: 10.1111/tpj.14015. Epub 2018 Jul 29.

7.

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration.

Deczkowska A, Keren-Shaul H, Weiner A, Colonna M, Schwartz M, Amit I.

Cell. 2018 May 17;173(5):1073-1081. doi: 10.1016/j.cell.2018.05.003. Review.

8.

Dicer Deficiency Differentially Impacts Microglia of the Developing and Adult Brain.

Varol D, Mildner A, Blank T, Shemer A, Barashi N, Yona S, David E, Boura-Halfon S, Segal-Hayoun Y, Chappell-Maor L, Keren-Shaul H, Leshkowitz D, Hornstein E, Fuhrmann M, Amit I, Maggio N, Prinz M, Jung S.

Immunity. 2017 Jun 20;46(6):1030-1044.e8. doi: 10.1016/j.immuni.2017.05.003.

9.

A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease.

Keren-Shaul H, Spinrad A, Weiner A, Matcovitch-Natan O, Dvir-Szternfeld R, Ulland TK, David E, Baruch K, Lara-Astaiso D, Toth B, Itzkovitz S, Colonna M, Schwartz M, Amit I.

Cell. 2017 Jun 15;169(7):1276-1290.e17. doi: 10.1016/j.cell.2017.05.018. Epub 2017 Jun 8.

10.

Single-cell transcriptome conservation in cryopreserved cells and tissues.

Guillaumet-Adkins A, Rodríguez-Esteban G, Mereu E, Mendez-Lago M, Jaitin DA, Villanueva A, Vidal A, Martinez-Marti A, Felip E, Vivancos A, Keren-Shaul H, Heath S, Gut M, Amit I, Gut I, Heyn H.

Genome Biol. 2017 Mar 1;18(1):45. doi: 10.1186/s13059-017-1171-9.

11.

Dissecting Immune Circuits by Linking CRISPR-Pooled Screens with Single-Cell RNA-Seq.

Jaitin DA, Weiner A, Yofe I, Lara-Astiaso D, Keren-Shaul H, David E, Salame TM, Tanay A, van Oudenaarden A, Amit I.

Cell. 2016 Dec 15;167(7):1883-1896.e15. doi: 10.1016/j.cell.2016.11.039.

12.

Extracellular Matrix Proteolysis by MT1-MMP Contributes to Influenza-Related Tissue Damage and Mortality.

Talmi-Frank D, Altboum Z, Solomonov I, Udi Y, Jaitin DA, Klepfish M, David E, Zhuravlev A, Keren-Shaul H, Winter DR, Gat-Viks I, Mandelboim M, Ziv T, Amit I, Sagi I.

Cell Host Microbe. 2016 Oct 12;20(4):458-470. doi: 10.1016/j.chom.2016.09.005.

13.

The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome.

Gury-BenAri M, Thaiss CA, Serafini N, Winter DR, Giladi A, Lara-Astiaso D, Levy M, Salame TM, Weiner A, David E, Shapiro H, Dori-Bachash M, Pevsner-Fischer M, Lorenzo-Vivas E, Keren-Shaul H, Paul F, Harmelin A, Eberl G, Itzkovitz S, Tanay A, Di Santo JP, Elinav E, Amit I.

Cell. 2016 Aug 25;166(5):1231-1246.e13. doi: 10.1016/j.cell.2016.07.043. Epub 2016 Aug 18.

14.

Microglia development follows a stepwise program to regulate brain homeostasis.

Matcovitch-Natan O, Winter DR, Giladi A, Vargas Aguilar S, Spinrad A, Sarrazin S, Ben-Yehuda H, David E, Zelada González F, Perrin P, Keren-Shaul H, Gury M, Lara-Astaiso D, Thaiss CA, Cohen M, Bahar Halpern K, Baruch K, Deczkowska A, Lorenzo-Vivas E, Itzkovitz S, Elinav E, Sieweke MH, Schwartz M, Amit I.

Science. 2016 Aug 19;353(6301):aad8670. doi: 10.1126/science.aad8670. Epub 2016 Jun 23.

15.

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors.

Paul F, Arkin Y, Giladi A, Jaitin DA, Kenigsberg E, Keren-Shaul H, Winter D, Lara-Astiaso D, Gury M, Weiner A, David E, Cohen N, Lauridsen FKB, Haas S, Schlitzer A, Mildner A, Ginhoux F, Jung S, Trumpp A, Porse BT, Tanay A, Amit I.

Cell. 2016 Jan 14;164(1-2):325. doi: 10.1016/j.cell.2015.12.046. Epub 2016 Jan 14. No abstract available.

16.

Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors.

Paul F, Arkin Y, Giladi A, Jaitin DA, Kenigsberg E, Keren-Shaul H, Winter D, Lara-Astiaso D, Gury M, Weiner A, David E, Cohen N, Lauridsen FK, Haas S, Schlitzer A, Mildner A, Ginhoux F, Jung S, Trumpp A, Porse BT, Tanay A, Amit I.

Cell. 2015 Dec 17;163(7):1663-77. doi: 10.1016/j.cell.2015.11.013. Epub 2015 Nov 25. Erratum in: Cell. 2016 Jan 14;164(1-2):325.

17.

Host microbiota constantly control maturation and function of microglia in the CNS.

Erny D, Hrabě de Angelis AL, Jaitin D, Wieghofer P, Staszewski O, David E, Keren-Shaul H, Mahlakoiv T, Jakobshagen K, Buch T, Schwierzeck V, Utermöhlen O, Chun E, Garrett WS, McCoy KD, Diefenbach A, Staeheli P, Stecher B, Amit I, Prinz M.

Nat Neurosci. 2015 Jul;18(7):965-77. doi: 10.1038/nn.4030. Epub 2015 Jun 1.

18.

Each cell counts: Hematopoiesis and immunity research in the era of single cell genomics.

Jaitin DA, Keren-Shaul H, Elefant N, Amit I.

Semin Immunol. 2015 Feb;27(1):67-71. doi: 10.1016/j.smim.2015.01.002. Epub 2015 Feb 26. Review.

PMID:
25727184
19.

Tissue-resident macrophage enhancer landscapes are shaped by the local microenvironment.

Lavin Y, Winter D, Blecher-Gonen R, David E, Keren-Shaul H, Merad M, Jung S, Amit I.

Cell. 2014 Dec 4;159(6):1312-26. doi: 10.1016/j.cell.2014.11.018.

20.

Chronic exposure to TGFβ1 regulates myeloid cell inflammatory response in an IRF7-dependent manner.

Cohen M, Matcovitch O, David E, Barnett-Itzhaki Z, Keren-Shaul H, Blecher-Gonen R, Jaitin DA, Sica A, Amit I, Schwartz M.

EMBO J. 2014 Dec 17;33(24):2906-21. doi: 10.15252/embj.201489293. Epub 2014 Nov 10.

21.

Immunogenetics. Chromatin state dynamics during blood formation.

Lara-Astiaso D, Weiner A, Lorenzo-Vivas E, Zaretsky I, Jaitin DA, David E, Keren-Shaul H, Mildner A, Winter D, Jung S, Friedman N, Amit I.

Science. 2014 Aug 22;345(6199):943-9. doi: 10.1126/science.1256271. Epub 2014 Aug 7.

22.

Digital cell quantification identifies global immune cell dynamics during influenza infection.

Altboum Z, Steuerman Y, David E, Barnett-Itzhaki Z, Valadarsky L, Keren-Shaul H, Meningher T, Mendelson E, Mandelboim M, Gat-Viks I, Amit I.

Mol Syst Biol. 2014 Feb 28;10:720. doi: 10.1002/msb.134947. Print 2014.

23.

Massively parallel single-cell RNA-seq for marker-free decomposition of tissues into cell types.

Jaitin DA, Kenigsberg E, Keren-Shaul H, Elefant N, Paul F, Zaretsky I, Mildner A, Cohen N, Jung S, Tanay A, Amit I.

Science. 2014 Feb 14;343(6172):776-9. doi: 10.1126/science.1247651.

24.

Pre-mRNA splicing is a determinant of nucleosome organization.

Keren-Shaul H, Lev-Maor G, Ast G.

PLoS One. 2013;8(1):e53506. doi: 10.1371/journal.pone.0053506. Epub 2013 Jan 10.

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