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Items: 18


MIBI-TOF: A multiplexed imaging platform relates cellular phenotypes and tissue structure.

Keren L, Bosse M, Thompson S, Risom T, Vijayaragavan K, McCaffrey E, Marquez D, Angoshtari R, Greenwald NF, Fienberg H, Wang J, Kambham N, Kirkwood D, Nolan G, Montine TJ, Galli SJ, West R, Bendall SC, Angelo M.

Sci Adv. 2019 Oct 9;5(10):eaax5851. doi: 10.1126/sciadv.aax5851. eCollection 2019 Oct.


Central dogma rates and the trade-off between precision and economy in gene expression.

Hausser J, Mayo A, Keren L, Alon U.

Nat Commun. 2019 Jan 8;10(1):68. doi: 10.1038/s41467-018-07391-8.


A Structured Tumor-Immune Microenvironment in Triple Negative Breast Cancer Revealed by Multiplexed Ion Beam Imaging.

Keren L, Bosse M, Marquez D, Angoshtari R, Jain S, Varma S, Yang SR, Kurian A, Van Valen D, West R, Bendall SC, Angelo M.

Cell. 2018 Sep 6;174(6):1373-1387.e19. doi: 10.1016/j.cell.2018.08.039.


Massively Parallel Interrogation of the Effects of Gene Expression Levels on Fitness.

Keren L, Hausser J, Lotan-Pompan M, Vainberg Slutskin I, Alisar H, Kaminski S, Weinberger A, Alon U, Milo R, Segal E.

Cell. 2016 Aug 25;166(5):1282-1294.e18. doi: 10.1016/j.cell.2016.07.024. Epub 2016 Aug 18.


A Minimalistic Resource Allocation Model to Explain Ubiquitous Increase in Protein Expression with Growth Rate.

Barenholz U, Keren L, Segal E, Milo R.

PLoS One. 2016 Apr 13;11(4):e0153344. doi: 10.1371/journal.pone.0153344. eCollection 2016.


Noise in gene expression is coupled to growth rate.

Keren L, van Dijk D, Weingarten-Gabbay S, Davidi D, Jona G, Weinberger A, Milo R, Segal E.

Genome Res. 2015 Dec;25(12):1893-902. doi: 10.1101/gr.191635.115. Epub 2015 Sep 9.


Probing the effect of promoters on noise in gene expression using thousands of designed sequences.

Sharon E, van Dijk D, Kalma Y, Keren L, Manor O, Yakhini Z, Segal E.

Genome Res. 2014 Oct;24(10):1698-706. doi: 10.1101/gr.168773.113. Epub 2014 Jul 16.


Fixated on fixation: using ChIP to interrogate the dynamics of chromatin interactions.

Keren L, Segal E.

Genome Biol. 2013 Nov 21;14(11):138. doi: 10.1186/gb4139.


Promoters maintain their relative activity levels under different growth conditions.

Keren L, Zackay O, Lotan-Pompan M, Barenholz U, Dekel E, Sasson V, Aidelberg G, Bren A, Zeevi D, Weinberger A, Alon U, Milo R, Segal E.

Mol Syst Biol. 2013 Oct 29;9:701. doi: 10.1038/msb.2013.59.


Sequence features of yeast and human core promoters that are predictive of maximal promoter activity.

Lubliner S, Keren L, Segal E.

Nucleic Acids Res. 2013 Jun;41(11):5569-81. doi: 10.1093/nar/gkt256. Epub 2013 Apr 17.


Measurements of the impact of 3' end sequences on gene expression reveal wide range and sequence dependent effects.

Shalem O, Carey L, Zeevi D, Sharon E, Keren L, Weinberger A, Dahan O, Pilpel Y, Segal E.

PLoS Comput Biol. 2013;9(3):e1002934. doi: 10.1371/journal.pcbi.1002934. Epub 2013 Mar 7.


Manipulating nucleosome disfavoring sequences allows fine-tune regulation of gene expression in yeast.

Raveh-Sadka T, Levo M, Shabi U, Shany B, Keren L, Lotan-Pompan M, Zeevi D, Sharon E, Weinberger A, Segal E.

Nat Genet. 2012 May 27;44(7):743-50. doi: 10.1038/ng.2305.


Inferring gene regulatory logic from high-throughput measurements of thousands of systematically designed promoters.

Sharon E, Kalma Y, Sharp A, Raveh-Sadka T, Levo M, Zeevi D, Keren L, Yakhini Z, Weinberger A, Segal E.

Nat Biotechnol. 2012 May 20;30(6):521-30. doi: 10.1038/nbt.2205.


Molecular epidemiology of methicillin-resistant Staphylococcus aureus in Israel: dissemination of global clones and unique features.

Adler A, Chmelnitsky I, Shitrit P, Sprecher H, Navon-Venezia S, Embon A, Khabra E, Paitan Y, Keren L, Halperin E, Carmeli Y, Schwaber MJ.

J Clin Microbiol. 2012 Jan;50(1):134-7. doi: 10.1128/JCM.05446-11. Epub 2011 Oct 26.


Compensation for differences in gene copy number among yeast ribosomal proteins is encoded within their promoters.

Zeevi D, Sharon E, Lotan-Pompan M, Lubling Y, Shipony Z, Raveh-Sadka T, Keren L, Levo M, Weinberger A, Segal E.

Genome Res. 2011 Dec;21(12):2114-28. doi: 10.1101/gr.119669.110. Epub 2011 Oct 18.


Self-targeting by CRISPR: gene regulation or autoimmunity?

Stern A, Keren L, Wurtzel O, Amitai G, Sorek R.

Trends Genet. 2010 Aug;26(8):335-40. doi: 10.1016/j.tig.2010.05.008. Epub 2010 Jul 1.


Hepatitis in selective IgA deficiency.

Benbassat J, Keren L, Zlotnic A.

Br Med J. 1973 Dec 29;4(5895):762-3.

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