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Items: 1 to 50 of 115

1.

Role of oral pathogens in the pathogenesis of intracranial aneurysm: review of existing evidence and potential mechanisms.

Hallikainen J, Keränen S, Savolainen J, Närhi M, Suominen AL, Ylöstalo P, Kellokoski J, Pyysalo M, Pussinen P, Rauramaa T, Frösen J.

Neurosurg Rev. 2020 Feb 7. doi: 10.1007/s10143-020-01253-y. [Epub ahead of print] Review.

PMID:
32034564
2.

Exploiting regulatory heterogeneity to systematically identify enhancers with high accuracy.

Arbel H, Basu S, Fisher WW, Hammonds AS, Wan KH, Park S, Weiszmann R, Booth BW, Keranen SV, Henriquez C, Shams Solari O, Bickel PJ, Biggin MD, Celniker SE, Brown JB.

Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):900-908. doi: 10.1073/pnas.1808833115. Epub 2018 Dec 31.

3.

REDfly: the transcriptional regulatory element database for Drosophila.

Rivera J, Keränen SVE, Gallo SM, Halfon MS.

Nucleic Acids Res. 2019 Jan 8;47(D1):D828-D834. doi: 10.1093/nar/gky957.

4.

The freezing method of cleavage stage embryos has no impact on the weight of the newborns.

Kaartinen N, Kananen K, Huhtala H, Keränen S, Tinkanen H.

J Assist Reprod Genet. 2016 Mar;33(3):393-399. doi: 10.1007/s10815-015-0642-8. Epub 2016 Jan 9.

5.

Short- and Long-Term Quality of Life and Bowel Function in Patients With MRI-Defined, High-Risk, Locally Advanced Rectal Cancer Treated With an Intensified Neoadjuvant Strategy in the Randomized Phase 2 EXPERT-C Trial.

Sclafani F, Peckitt C, Cunningham D, Tait D, Giralt J, Glimelius B, Keränen SR, Bateman A, Hickish T, Tabernero J, Thomas J, Brown G, Oates J, Chau I.

Int J Radiat Oncol Biol Phys. 2015 Oct 1;93(2):303-12. doi: 10.1016/j.ijrobp.2015.03.038. Epub 2015 Apr 4.

PMID:
26031368
6.

Volumetric Semantic Segmentation using Pyramid Context Features.

Barron JT, Arbeláez P, Keränen SV, Biggin MD, Knowles DW, Malik J.

Proc IEEE Int Conf Comput Vis. 2013 Dec;2013:3448-3455.

7.

Northern excess in adolescent male firearm suicides: a register-based regional study from Finland, 1972-2009.

Lahti A, Keränen S, Hakko H, Riala K, Räsänen P.

Eur Child Adolesc Psychiatry. 2014 Jan;23(1):45-52. doi: 10.1007/s00787-013-0422-x. Epub 2013 May 17.

PMID:
23680994
8.

Lobar lung resection in elderly patients with non-small cell lung carcinoma: impact of cardiac comorbidity on surgical outcome.

Senbaklavaci O, Taspinar H, Hartert M, Ergun S, Keranen S, Vahl CF.

Swiss Med Wkly. 2012 Dec 21;142:w13742. doi: 10.4414/smw.2012.13742. eCollection 2012.

9.

A conserved developmental patterning network produces quantitatively different output in multiple species of Drosophila.

Fowlkes CC, Eckenrode KB, Bragdon MD, Meyer M, Wunderlich Z, Simirenko L, Luengo Hendriks CL, Keränen SV, Henriquez C, Knowles DW, Biggin MD, Eisen MB, DePace AH.

PLoS Genet. 2011 Oct;7(10):e1002346. doi: 10.1371/journal.pgen.1002346. Epub 2011 Oct 27.

10.

Youth suicide trends in Finland, 1969-2008.

Lahti A, Räsänen P, Riala K, Keränen S, Hakko H.

J Child Psychol Psychiatry. 2011 Sep;52(9):984-91. doi: 10.1111/j.1469-7610.2011.02369.x. Epub 2011 Feb 5.

PMID:
21294729
11.

Nonparametric identification of regulatory interactions from spatial and temporal gene expression data.

Aswani A, Keränen SV, Brown J, Fowlkes CC, Knowles DW, Biggin MD, Bickel P, Tomlin CJ.

BMC Bioinformatics. 2010 Aug 4;11:413. doi: 10.1186/1471-2105-11-413.

12.

Coupling visualization and data analysis for knowledge discovery from multi-dimensional scientific data.

Rübel O, Ahern S, Bethel EW, Biggin MD, Childs H, Cormier-Michel E, Depace A, Eisen MB, Fowlkes CC, Geddes CG, Hagen H, Hamann B, Huang MY, Keränen SV, Knowles DW, Hendriks CL, Malik J, Meredith J, Messmer P, Prabhat, Ushizima D, Weber GH, Wu K.

Procedia Comput Sci. 2010 May;1(1):1757-1764.

13.

Integrating data clustering and visualization for the analysis of 3D gene expression data.

Rübel O, Weber GH, Huang MY, Bethel EW, Biggin MD, Fowlkes CC, Luengo Hendriks CL, Keränen SV, Eisen MB, Knowles DW, Malik J, Hagen H, Hamann B.

IEEE/ACM Trans Comput Biol Bioinform. 2010 Jan-Mar;7(1):64-79. doi: 10.1109/TCBB.2008.49.

PMID:
20150669
14.

Developmental roles of 21 Drosophila transcription factors are determined by quantitative differences in binding to an overlapping set of thousands of genomic regions.

MacArthur S, Li XY, Li J, Brown JB, Chu HC, Zeng L, Grondona BP, Hechmer A, Simirenko L, Keränen SV, Knowles DW, Stapleton M, Bickel P, Biggin MD, Eisen MB.

Genome Biol. 2009;10(7):R80. doi: 10.1186/gb-2009-10-7-r80. Epub 2009 Jul 23.

15.

Visual exploration of three-dimensional gene expression using physical views and linked abstract views.

Weber GH, Rübel O, Huang MY, DePace AH, Fowlkes CC, Keränen SV, Luengo Hendriks CL, Hagen H, Knowles DW, Malik J, Biggin MD, Hamann B.

IEEE/ACM Trans Comput Biol Bioinform. 2009 Apr-Jun;6(2):296-309. doi: 10.1109/TCBB.2007.70249.

16.

A quantitative spatiotemporal atlas of gene expression in the Drosophila blastoderm.

Fowlkes CC, Hendriks CL, Keränen SV, Weber GH, Rübel O, Huang MY, Chatoor S, DePace AH, Simirenko L, Henriquez C, Beaton A, Weiszmann R, Celniker S, Hamann B, Knowles DW, Biggin MD, Eisen MB, Malik J.

Cell. 2008 Apr 18;133(2):364-74. doi: 10.1016/j.cell.2008.01.053.

17.

Automatic channel unmixing for high-throughput quantitative analysis of fluorescence images.

Luengo Hendriks CL, Keränen SV, Biggin MD, Knowles DW.

Opt Express. 2007 Sep 17;15(19):12306-17.

PMID:
19547599
18.

The transmembrane domain is sufficient for Sbh1p function, its association with the Sec61 complex, and interaction with Rtn1p.

Feng D, Zhao X, Soromani C, Toikkanen J, Römisch K, Vembar SS, Brodsky JL, Keränen S, Jäntti J.

J Biol Chem. 2007 Oct 19;282(42):30618-28. Epub 2007 Aug 14.

19.

A cytosolic splice variant of Cab45 interacts with Munc18b and impacts on amylase secretion by pancreatic acini.

Lam PP, Hyvärinen K, Kauppi M, Cosen-Binker L, Laitinen S, Keränen S, Gaisano HY, Olkkonen VM.

Mol Biol Cell. 2007 Jul;18(7):2473-80. Epub 2007 Apr 18.

20.

Three-dimensional morphology and gene expression in the Drosophila blastoderm at cellular resolution II: dynamics.

Keränen SV, Fowlkes CC, Luengo Hendriks CL, Sudar D, Knowles DW, Malik J, Biggin MD.

Genome Biol. 2006;7(12):R124.

21.

Three-dimensional morphology and gene expression in the Drosophila blastoderm at cellular resolution I: data acquisition pipeline.

Luengo Hendriks CL, Keränen SV, Fowlkes CC, Simirenko L, Weber GH, DePace AH, Henriquez C, Kaszuba DW, Hamann B, Eisen MB, Malik J, Sudar D, Biggin MD, Knowles DW.

Genome Biol. 2006;7(12):R123.

22.

Identification of mutations causing temperature-sensitive defects in Semliki Forest virus RNA synthesis.

Lulla V, Merits A, Sarin P, Kääriäinen L, Keränen S, Ahola T.

J Virol. 2006 Mar;80(6):3108-11.

24.

Molecular interactions position Mso1p, a novel PTB domain homologue, in the interface of the exocyst complex and the exocytic SNARE machinery in yeast.

Knop M, Miller KJ, Mazza M, Feng D, Weber M, Keränen S, Jäntti J.

Mol Biol Cell. 2005 Oct;16(10):4543-56. Epub 2005 Jul 19.

26.

Simulation study on effects of signaling network structure on the developmental increase in complexity.

Keränen SV.

J Theor Biol. 2004 Nov 7;231(1):3-21. Erratum in: J Theor Biol. 2006 Sep 7;242(1):263.

PMID:
15363926
27.

Screening for novel essential genes of Saccharomyces cerevisiae involved in protein secretion.

Davydenko SG, Juselius JK, Munder T, Bogengruber E, Jäntti J, Keränen S.

Yeast. 2004 Apr 30;21(6):463-71.

28.

Mapping of sporulation-specific functions in the yeast syntaxin gene SSO1.

Oyen M, Jäntti J, Keränen S, Ronne H.

Curr Genet. 2004 Feb;45(2):76-82. Epub 2003 Dec 2.

PMID:
14652692
29.
30.

Functional inactivation of the conserved Sem1p in yeast by intrabodies.

Reinman M, Jäntti J, Alfthan K, Keränen S, Söderlund H, Takkinen K.

Yeast. 2003 Sep;20(12):1071-84.

31.

[On mental health of adolescents and diagnosing substance abuse disorders in connection to emergency care].

Keränen S, Laukkanen E, Hintikka J.

Duodecim. 2003;119(12):1147-53. Finnish. No abstract available.

PMID:
12868361
32.

The beta subunit of the Sec61p endoplasmic reticulum translocon interacts with the exocyst complex in Saccharomyces cerevisiae.

Toikkanen JH, Miller KJ, Söderlund H, Jäntti J, Keränen S.

J Biol Chem. 2003 Jun 6;278(23):20946-53. Epub 2003 Mar 28.

33.

Enamel knots as signaling centers linking tooth morphogenesis and odontoblast differentiation.

Thesleff I, Keränen S, Jernvall J.

Adv Dent Res. 2001 Aug;15:14-8. Review.

PMID:
12640732
34.

Characterisation of two 14-3-3 genes from Trichoderma reesei: interactions with yeast secretory pathway components.

Vasara T, Keränen S, Penttilä M, Saloheimo M.

Biochim Biophys Acta. 2002 Jun 12;1590(1-3):27-40.

35.

Interactions of the Trichoderma reesei rho3 with the secretory pathway in yeast and T. reesei.

Vasara T, Salusjärvi L, Raudaskoski M, Keränen S, Penttilä M, Saloheimo M.

Mol Microbiol. 2001 Dec;42(5):1349-61.

36.
37.

Characterization of the sec1-1 and sec1-11 mutations.

Brummer MH, Kivinen KJ, Jäntti J, Toikkanen J, Söderlund H, Keränen S.

Yeast. 2001 Dec;18(16):1525-36.

38.

Trichoderma reesei rho3 a homologue of yeast RH03 suppresses the growth defect of yeast sec15-1 mutation.

Vasara T, Saloheimo M, Keränen S, Penttilä M.

Curr Genet. 2001 Sep;40(2):119-27.

PMID:
11680821
39.

The GDI1 genes from Kluyveromyces lactis and Pichia pastoris: cloning and functional expression in Saccharomyces cerevisiae.

Brummer MH, Richard P, Sundqvist L, Väänänen R, Keränen S.

Yeast. 2001 Jul;18(10):897-902.

40.

Evolutionary modification of development in mammalian teeth: quantifying gene expression patterns and topography.

Jernvall J, Keränen SV, Thesleff I.

Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14444-8.

41.

Exocytosis requires asymmetry in the central layer of the SNARE complex.

Ossig R, Schmitt HD, de Groot B, Riedel D, Keränen S, Ronne H, Grubmüller H, Jahn R.

EMBO J. 2000 Nov 15;19(22):6000-10.

42.

Role of adenine nucleotide translocator 1 in mtDNA maintenance.

Kaukonen J, Juselius JK, Tiranti V, Kyttälä A, Zeviani M, Comi GP, Keränen S, Peltonen L, Suomalainen A.

Science. 2000 Aug 4;289(5480):782-5.

43.

Munc18-2, a functional partner of syntaxin 3, controls apical membrane trafficking in epithelial cells.

Riento K, Kauppi M, Keranen S, Olkkonen VM.

J Biol Chem. 2000 May 5;275(18):13476-83.

44.

Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast.

Bagnat M, Keränen S, Shevchenko A, Shevchenko A, Simons K.

Proc Natl Acad Sci U S A. 2000 Mar 28;97(7):3254-9.

45.

Gene expression patterns associated with suppression of odontogenesis in mouse and vole diastema regions.

Keränen SV, Kettunen P, Aberg T, Thesleff I, Jernvall J.

Dev Genes Evol. 1999 Aug;209(8):495-506.

PMID:
10415326
46.

DNA polymerase epsilon catalytic domains are dispensable for DNA replication, DNA repair, and cell viability.

Kesti T, Flick K, Keränen S, Syväoja JE, Wittenberg C.

Mol Cell. 1999 May;3(5):679-85.

47.

SEM1, a homologue of the split hand/split foot malformation candidate gene Dss1, regulates exocytosis and pseudohyphal differentiation in yeast.

Jäntti J, Lahdenranta J, Olkkonen VM, Söderlund H, Keränen S.

Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):909-14.

48.

Association of developmental regulatory genes with the development of different molar tooth shapes in two species of rodents.

Keränen SV, Aberg T, Kettunen P, Thesleff I, Jernvall J.

Dev Genes Evol. 1998 Nov;208(9):477-86.

PMID:
9799429
49.

A yeast t-SNARE involved in endocytosis.

Séron K, Tieaho V, Prescianotto-Baschong C, Aust T, Blondel MO, Guillaud P, Devilliers G, Rossanese OW, Glick BS, Riezman H, Keränen S, Haguenauer-Tsapis R.

Mol Biol Cell. 1998 Oct;9(10):2873-89.

50.

Functional analysis of the cellobiohydrolase I promoter of the filamentous fungus Trichoderma reesei.

Ilmén M, Onnela ML, Klemsdal S, Keränen S, Pentilä M.

Mol Gen Genet. 1998 Feb;257(3):386. No abstract available.

PMID:
9547139

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