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Items: 1 to 50 of 53

1.

Somatic mutations and T-cell clonality in patients with immunodeficiency.

Savola P, Martelius T, Kankainen M, Huuhtanen J, Lundgren S, Koski Y, Eldfors S, Kelkka T, Keränen MAI, Ellonen P, Kovanen PE, Kytölä S, Saarela J, Lähdesmäki H, Seppänen MRJ, Mustjoki S.

Haematologica. 2019 Dec 19. pii: haematol.2019.220889. doi: 10.3324/haematol.2019.220889. [Epub ahead of print]

2.

Integrated drug profiling and CRISPR screening identify essential pathways for CAR T cell cytotoxicity.

Dufva O, Koski J, Maliniemi P, Ianevski A, Klievink J, Leitner J, Pölönen P, Hohtari H, Saeed K, Hannunen T, Ellonen P, Steinberger P, Kankainen M, Aittokallio T, Keränen MAI, Korhonen M, Mustjoki S.

Blood. 2019 Dec 12. pii: blood.2019002121. doi: 10.1182/blood.2019002121. [Epub ahead of print]

PMID:
31830245
3.

Clonal hematopoiesis in patients with rheumatoid arthritis.

Savola P, Lundgren S, Keränen MAI, Almusa H, Ellonen P, Leirisalo-Repo M, Kelkka T, Mustjoki S.

Blood Cancer J. 2018 Jul 26;8(8):69. doi: 10.1038/s41408-018-0107-2. No abstract available.

4.

Hypoxia-inducible factor controls immunoregulatory properties of myeloid cells in mouse cardiac allografts - an experimental study.

Keränen MAI, Raissadati A, Nykänen AI, Dashkevich A, Tuuminen R, Krebs R, Johnson RS, Syrjälä SO, Lemström KB.

Transpl Int. 2019 Jan;32(1):95-106. doi: 10.1111/tri.13310. Epub 2018 Jul 13.

5.

Vascular Endothelial Growth Factor-B Overexpressing Hearts Are Not Protected From Transplant-Associated Ischemia-Reperfusion Injury.

Raissadati A, Tuuminen R, Dashkevich A, Bry M, Kivelä R, Anisimov A, Syrjälä S, Arnaudova R, Rouvinen E, Keränen MA, Krebs R, Nykänen AI, Lemström KB.

Exp Clin Transplant. 2017 Apr;15(2):203-212. doi: 10.6002/ect.2016.0181. Epub 2016 Sep 1.

6.

Increased myeloid cell hypoxia-inducible factor-1 delays obliterative airway disease in the mouse.

Ropponen JO, Keränen MA, Raissadati A, Nykänen AI, Krebs R, Lemström KB, Tikkanen JM.

J Heart Lung Transplant. 2016 May;35(5):671-8. doi: 10.1016/j.healun.2015.12.021. Epub 2016 Jan 6.

PMID:
26856676
7.

T cells and cancer - why do the killers become exhausted?

Brück O, Keränen M, Dufva O, Kreutzman A, Mustjoki S.

Duodecim. 2016;132(21):1984-92. Review.

PMID:
29190050
8.

Ischemia-Reperfusion Injury Enhances Lymphatic Endothelial VEGFR3 and Rejection in Cardiac Allografts.

Dashkevich A, Raissadati A, Syrjälä SO, Zarkada G, Keränen MA, Tuuminen R, Krebs R, Anisimov A, Jeltsch M, Leppänen VM, Alitalo K, Nykänen AI, Lemström KB.

Am J Transplant. 2016 Apr;16(4):1160-72. doi: 10.1111/ajt.13564. Epub 2015 Dec 21.

9.

Platelet-derived Growth Factor-B Protects Rat Cardiac Allografts From Ischemia-reperfusion Injury.

Tuuminen R, Dashkevich A, Keränen MA, Raissadati A, Krebs R, Jokinen JJ, Arnaudova R, Rouvinen E, Ylä-Herttuala S, Nykänen AI, Lemström KB.

Transplantation. 2016 Feb;100(2):303-13. doi: 10.1097/TP.0000000000000909.

PMID:
26371596
10.

Donor Heart Treatment With COMP-Ang1 Limits Ischemia-Reperfusion Injury and Rejection of Cardiac Allografts.

Syrjälä SO, Nykänen AI, Tuuminen R, Raissadati A, Keränen MA, Arnaudova R, Krebs R, Koh GY, Alitalo K, Lemström KB.

Am J Transplant. 2015 Aug;15(8):2075-84. doi: 10.1111/ajt.13296. Epub 2015 May 1.

11.

Angiopoietin-2 inhibition prevents transplant ischemia-reperfusion injury and chronic rejection in rat cardiac allografts.

Syrjälä SO, Tuuminen R, Nykänen AI, Raissadati A, Dashkevich A, Keränen MA, Arnaudova R, Krebs R, Leow CC, Saharinen P, Alitalo K, Lemström KB.

Am J Transplant. 2014 May;14(5):1096-108. doi: 10.1111/ajt.12672. Epub 2014 Apr 7.

12.

Ex vivo intracoronary gene transfer of adeno-associated virus 2 leads to superior transduction over serotypes 8 and 9 in rat heart transplants.

Raissadati A, Jokinen JJ, Syrjälä SO, Keränen MA, Krebs R, Tuuminen R, Arnaudova R, Rouvinen E, Anisimov A, Soronen J, Pajusola K, Alitalo K, Nykänen AI, Lemström K.

Transpl Int. 2013 Nov;26(11):1126-37. doi: 10.1111/tri.12182. Epub 2013 Sep 19.

13.

Donor simvastatin treatment prevents ischemia-reperfusion and acute kidney injury by preserving microvascular barrier function.

Tuuminen R, Nykänen AI, Saharinen P, Gautam P, Keränen MA, Arnaudova R, Rouvinen E, Helin H, Tammi R, Rilla K, Krebs R, Lemström KB.

Am J Transplant. 2013 Aug;13(8):2019-34. doi: 10.1111/ajt.12315. Epub 2013 Jun 14.

14.

Differential effects of pharmacological HIF preconditioning of donors versus recipients in rat cardiac allografts.

Keränen MA, Tuuminen R, Syrjälä S, Krebs R, Walkinshaw G, Flippin LA, Arend M, Koskinen PK, Nykänen AI, Lemström KB.

Am J Transplant. 2013 Mar;13(3):600-10. doi: 10.1111/ajt.12064. Epub 2013 Jan 17.

15.

Regulation of root greening by light and auxin/cytokinin signaling in Arabidopsis.

Kobayashi K, Baba S, Obayashi T, Sato M, Toyooka K, Keränen M, Aro EM, Fukaki H, Ohta H, Sugimoto K, Masuda T.

Plant Cell. 2012 Mar;24(3):1081-95. doi: 10.1105/tpc.111.092254. Epub 2012 Mar 13.

16.

Effect of simvastatin on development of obliterative airway disease: an experimental study.

Ropponen JO, Syrjälä SO, Hollmén M, Tuuminen R, Krebs R, Keränen MA, Vaali K, Nykänen AI, Lemström KB, Tikkanen JM.

J Heart Lung Transplant. 2012 Feb;31(2):194-203. doi: 10.1016/j.healun.2011.11.008.

PMID:
22305382
17.

Donor simvastatin treatment abolishes rat cardiac allograft ischemia/reperfusion injury and chronic rejection through microvascular protection.

Tuuminen R, Syrjälä S, Krebs R, Keränen MA, Koli K, Abo-Ramadan U, Neuvonen PJ, Tikkanen JM, Nykänen AI, Lemström KB.

Circulation. 2011 Sep 6;124(10):1138-50. doi: 10.1161/CIRCULATIONAHA.110.005249. Epub 2011 Aug 15.

PMID:
21844074
18.

Excitation energy transfer in the LHC-II trimer: from carotenoids to chlorophylls in space and time.

Martiskainen J, Kananavičius R, Linnanto J, Lehtivuori H, Keränen M, Aumanen V, Tkachenko N, Korppi-Tommola J.

Photosynth Res. 2011 Feb;107(2):195-207. doi: 10.1007/s11120-011-9626-4. Epub 2011 Feb 2.

PMID:
21287272
19.

Nodularin uptake and induction of oxidative stress in spinach (Spinachia oleracea).

Lehtimäki N, Shunmugam S, Jokela J, Wahlsten M, Carmel D, Keränen M, Sivonen K, Aro EM, Allahverdiyeva Y, Mulo P.

J Plant Physiol. 2011 Apr 15;168(6):594-600. doi: 10.1016/j.jplph.2010.09.013. Epub 2010 Nov 19.

PMID:
21093957
20.

Dynamic changes in the proteome of Synechocystis 6803 in response to CO(2) limitation revealed by quantitative proteomics.

Battchikova N, Vainonen JP, Vorontsova N, Keranen M, Carmel D, Aro EM.

J Proteome Res. 2010 Nov 5;9(11):5896-912. doi: 10.1021/pr100651w. Epub 2010 Sep 20.

PMID:
20795750
21.

Increased Th17 rather than Th1 alloimmune response is associated with cardiac allograft vasculopathy after hypothermic preservation in the rat.

Syrjälä SO, Keränen MA, Tuuminen R, Nykänen AI, Tammi M, Krebs R, Lemström KB.

J Heart Lung Transplant. 2010 Sep;29(9):1047-57. doi: 10.1016/j.healun.2010.04.012. Epub 2010 Jun 29.

PMID:
20591689
22.

Cardiomyocyte-targeted HIF-1alpha gene therapy inhibits cardiomyocyte apoptosis and cardiac allograft vasculopathy in the rat.

Keränen MA, Nykänen AI, Krebs R, Pajusola K, Tuuminen R, Alitalo K, Lemström KB.

J Heart Lung Transplant. 2010 Sep;29(9):1058-66. doi: 10.1016/j.healun.2010.05.021. Epub 2010 Jun 26.

PMID:
20580263
23.

Targeting lymphatic vessel activation and CCL21 production by vascular endothelial growth factor receptor-3 inhibition has novel immunomodulatory and antiarteriosclerotic effects in cardiac allografts.

Nykänen AI, Sandelin H, Krebs R, Keränen MA, Tuuminen R, Kärpänen T, Wu Y, Pytowski B, Koskinen PK, Ylä-Herttuala S, Alitalo K, Lemström KB.

Circulation. 2010 Mar 30;121(12):1413-22. doi: 10.1161/CIRCULATIONAHA.109.910703. Epub 2010 Mar 15.

PMID:
20231530
24.

Detection of human norovirus from frozen raspberries in a cluster of gastroenteritis outbreaks.

Maunula L, Roivainen M, Keränen M, Mäkela S, Söderberg K, Summa M, von Bonsdorff CH, Lappalainen M, Korhonen T, Kuusi M, Niskanen T.

Euro Surveill. 2009 Dec 10;14(49). pii: 19435.

25.

Detection of aqueous mercuric ion with a structurally simple 8-hydroxyquinoline derived ON-OFF fluorosensor.

Vaswani KG, Keränen MD.

Inorg Chem. 2009 Jul 6;48(13):5797-800. doi: 10.1021/ic9004517.

PMID:
19496544
26.

PDGF-A, -C, and -D but not PDGF-B increase TGF-beta1 and chronic rejection in rat cardiac allografts.

Tuuminen R, Nykänen AI, Krebs R, Soronen J, Pajusola K, Keränen MA, Koskinen PK, Alitalo K, Lemström KB.

Arterioscler Thromb Vasc Biol. 2009 May;29(5):691-8. doi: 10.1161/ATVBAHA.108.178558. Epub 2009 Feb 12.

PMID:
19213942
27.

Chloroplast NADPH-thioredoxin reductase interacts with photoperiodic development in Arabidopsis.

Lepistö A, Kangasjärvi S, Luomala EM, Brader G, Sipari N, Keränen M, Keinänen M, Rintamäki E.

Plant Physiol. 2009 Mar;149(3):1261-76. doi: 10.1104/pp.108.133777. Epub 2009 Jan 16.

28.

Comparative analysis of leaf-type ferredoxin-NADP oxidoreductase isoforms in Arabidopsis thaliana.

Lintala M, Allahverdiyeva Y, Kangasjärvi S, Lehtimäki N, Keränen M, Rintamäki E, Aro EM, Mulo P.

Plant J. 2009 Mar;57(6):1103-15. doi: 10.1111/j.1365-313X.2008.03753.x. Epub 2008 Nov 28.

29.

VEGFR-1 and -2 regulate inflammation, myocardial angiogenesis, and arteriosclerosis in chronically rejecting cardiac allografts.

Raisky O, Nykänen AI, Krebs R, Hollmén M, Keränen MA, Tikkanen JM, Sihvola R, Alhonen L, Salven P, Wu Y, Hicklin DJ, Alitalo K, Koskinen PK, Lemström KB.

Arterioscler Thromb Vasc Biol. 2007 Apr;27(4):819-25. Epub 2007 Feb 8.

PMID:
17290032
30.

Effect of graft preservation and acute rejection on hypoxia-inducible factor-1 in rat cardiac allografts.

Keränen MA, Nykänen AI, Krebs R, Tuuminen R, Sandelin H, Koskinen PK, Lemström KB.

Transplant Proc. 2006 Dec;38(10):3372-3.

PMID:
17175275
31.

The effect of platelet-derived growth factor ligands in rat cardiac allograft vasculopathy and fibrosis.

Tuuminen R, Nykänen A, Keränen MA, Krebs R, Alitalo K, Koskinen PK, Lemström KB.

Transplant Proc. 2006 Dec;38(10):3271-3.

PMID:
17175246
32.

Role of the RNA2 3' non-translated region of Blackcurrant reversion nepovirus in translational regulation.

Karetnikov A, Keränen M, Lehto K.

Virology. 2006 Oct 10;354(1):178-91. Epub 2006 Jul 31.

33.

Angiogenic growth factors in cardiac allograft rejection.

Nykänen AI, Tikkanen JM, Krebs R, Keränen MA, Sihvola RK, Sandelin H, Tuuminen R, Raisky O, Koskinen PK, Lemström KB.

Transplantation. 2006 Jul 15;82(1 Suppl):S22-4. Review. Erratum in: Transplantation. 2006 Sep 15;82(5):721.

PMID:
16829789
34.

Common protective and diverse smooth muscle cell effects of AAV-mediated angiopoietin-1 and -2 expression in rat cardiac allograft vasculopathy.

Nykänen AI, Pajusola K, Krebs R, Keränen MA, Raisky O, Koskinen PK, Alitalo K, Lemström KB.

Circ Res. 2006 Jun 9;98(11):1373-80. Epub 2006 May 11.

PMID:
16690881
35.

Evidence for the role of the oxygen-evolving manganese complex in photoinhibition of Photosystem II.

Hakala M, Tuominen I, Keränen M, Tyystjärvi T, Tyystjärvi E.

Biochim Biophys Acta. 2005 Jan 7;1706(1-2):68-80.

37.

Sequential hydroformylation/aldol reactions: versatile and controllable access to functionalised carbocycles from unsaturated carbonyl compounds.

Keränen MD, Kot K, Hollmann C, Eilbracht P.

Org Biomol Chem. 2004 Nov 21;2(22):3379-84. Epub 2004 Oct 11.

PMID:
15534717
39.

Syntheses of D- and L-Mannose, Gulose, and Talose via Diastereoselective and Enantioselective Dihydroxylation Reactions.

Harris JM, Keranen MD, O'Doherty GA.

J Org Chem. 1999 Apr 30;64(9):2982-2983. No abstract available.

PMID:
11674384
40.

UV light induced surface expansion phenomenon of hybrid glass thin films.

Rantala J, Karkkainen A, Hiltunen J, Keranen M, Kololuoma T, Descour M.

Opt Express. 2001 Jun 18;8(13):682-7.

PMID:
19421258
41.

Syntheses of four D- and L-hexoses via diastereoselective and enantioselective dihydroxylation reactions.

Harris JM, Keränen MD, Nguyen H, Young VG, O'Doherty GA.

Carbohydr Res. 2000 Aug 18;328(1):17-36.

PMID:
11005573
42.

Lip cancer in Northern Finland: changing incidence and clinical characteristics.

Alho OP, Keränen MR, Kantola S, Riihimäki S, Jokinen K, Alho P, Nuutinen J.

J Oral Pathol Med. 2000 Aug;29(7):299-302.

PMID:
10947244
43.

Type XIII collagen forms homotrimers with three triple helical collagenous domains and its association into disulfide-bonded trimers is enhanced by prolyl 4-hydroxylase.

Snellman A, Keränen MR, Hägg PO, Lamberg A, Hiltunen JK, Kivirikko KI, Pihlajaniemi T.

J Biol Chem. 2000 Mar 24;275(12):8936-44.

44.

The Kautsky curve is a built-in barcode.

Tyystjärvi E, Koski A, Keränen M, Nevalainen O.

Biophys J. 1999 Aug;77(2):1159-67.

45.

Phenotypic heterogeneity in motor neuron disease patients with CuZn-superoxide dismutase mutations in Scandinavia.

Andersen PM, Nilsson P, Keränen ML, Forsgren L, Hägglund J, Karlsborg M, Ronnevi LO, Gredal O, Marklund SL.

Brain. 1997 Oct;120 ( Pt 10):1723-37.

PMID:
9365366
46.

Autosomal recessive adult-onset amyotrophic lateral sclerosis associated with homozygosity for Asp90Ala CuZn-superoxide dismutase mutation. A clinical and genealogical study of 36 patients.

Andersen PM, Forsgren L, Binzer M, Nilsson P, Ala-Hurula V, Keränen ML, Bergmark L, Saarinen A, Haltia T, Tarvainen I, Kinnunen E, Udd B, Marklund SL.

Brain. 1996 Aug;119 ( Pt 4):1153-72. Erratum in: Brain 1998 Jan;121(Pt 1):187.

PMID:
8813280
47.

[Familial amyotrophic lateral sclerosis].

Keränen ML, Ala-Hurula VM, Saarinen A, Andersen PM, Marklund SL.

Duodecim. 1996;112(21):2026-30. Finnish. No abstract available.

PMID:
10605205
48.

[Spontaneous dissection of cephalic artery as a cause of subarachnoidal bleeding].

Keränen ML, Pykäläinen E.

Duodecim. 1996;112(8):723-4. Finnish. No abstract available.

PMID:
10592646
49.

Amyotrophic lateral sclerosis associated with homozygosity for an Asp90Ala mutation in CuZn-superoxide dismutase.

Andersen PM, Nilsson P, Ala-Hurula V, Keränen ML, Tarvainen I, Haltia T, Nilsson L, Binzer M, Forsgren L, Marklund SL.

Nat Genet. 1995 May;10(1):61-6.

PMID:
7647793
50.

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