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Items: 30


Several Polyphosphate Kinase 2 Enzymes Catalyse the Production of Adenosine 5'-Polyphosphates.

Mordhorst S, Singh J, Mohr MKF, Hinkelmann R, Keppler M, Jessen HJ, Andexer JN.

Chembiochem. 2019 Apr 15;20(8):1019-1022. doi: 10.1002/cbic.201800704. Epub 2019 Feb 28.


ALIX Regulates Tumor-Mediated Immunosuppression by Controlling EGFR Activity and PD-L1 Presentation.

Monypenny J, Milewicz H, Flores-Borja F, Weitsman G, Cheung A, Chowdhury R, Burgoyne T, Arulappu A, Lawler K, Barber PR, Vicencio JM, Keppler M, Wulaningsih W, Davidson SM, Fraternali F, Woodman N, Turmaine M, Gillett C, Franz D, Quezada SA, Futter CE, Von Kriegsheim A, Kolch W, Vojnovic B, Carlton JG, Ng T.

Cell Rep. 2018 Jul 17;24(3):630-641. doi: 10.1016/j.celrep.2018.06.066.


Detecting intratumoral heterogeneity of EGFR activity by liposome-based in vivo transfection of a fluorescent biosensor.

Weitsman G, Mitchell NJ, Evans R, Cheung A, Kalber TL, Bofinger R, Fruhwirth GO, Keppler M, Wright ZVF, Barber PR, Gordon P, de Koning T, Wulaningsih W, Sander K, Vojnovic B, Ameer-Beg S, Lythgoe M, Arnold JN, Årstad E, Festy F, Hailes HC, Tabor AB, Ng T.

Oncogene. 2017 Jun 22;36(25):3618-3628. doi: 10.1038/onc.2016.522. Epub 2017 Feb 6.


Fatal Human Meningoencephalitis due to Halicephalobus Nematodes, Germany.

Monoranu CM, Müllges W, Keppler M, Brehm K, Ondrejka SL, Muntau B, Tannich E, Müller-Hermelink HK, Tappe D.

Open Forum Infect Dis. 2015 May 22;2(2):ofv061. doi: 10.1093/ofid/ofv061. eCollection 2015 Apr.


A multi-functional imaging approach to high-content protein interaction screening.

Matthews DR, Fruhwirth GO, Weitsman G, Carlin LM, Ofo E, Keppler M, Barber PR, Tullis ID, Vojnovic B, Ng T, Ameer-Beg SM.

PLoS One. 2012;7(4):e33231. doi: 10.1371/journal.pone.0033231. Epub 2012 Apr 10.


A targeted siRNA screen identifies regulators of Cdc42 activity at the natural killer cell immunological synapse.

Carlin LM, Evans R, Milewicz H, Fernandes L, Matthews DR, Perani M, Levitt J, Keppler MD, Monypenny J, Coolen T, Barber PR, Vojnovic B, Suhling K, Fraternali F, Ameer-Beg S, Parker PJ, Thomas NS, Ng T.

Sci Signal. 2011 Nov 29;4(201):ra81. doi: 10.1126/scisignal.2001729.


Lipopolyplex ternary delivery systems incorporating C14 glycerol-based lipids.

Kudsiova L, Fridrich B, Ho J, Mustapa MF, Campbell F, Welser K, Keppler M, Ng T, Barlow DJ, Tabor AB, Hailes HC, Lawrence MJ.

Mol Pharm. 2011 Oct 3;8(5):1831-47. doi: 10.1021/mp2001796. Epub 2011 Aug 17.


Lipid chain geometry of C14 glycerol-based lipids: effect on lipoplex structure and transfection.

Kudsiova L, Ho J, Fridrich B, Harvey R, Keppler M, Ng T, Hart SL, Tabor AB, Hailes HC, Lawrence MJ.

Mol Biosyst. 2011 Feb;7(2):422-36. doi: 10.1039/c0mb00149j. Epub 2010 Nov 8.


Visualisation of signalling in immune cells.

Carlin LM, Makrogianneli K, Keppler M, Fruhwirth GO, Ng T.

Methods Mol Biol. 2010;616:97-113. doi: 10.1007/978-1-60761-461-6_7.


The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress.

Morris JR, Boutell C, Keppler M, Densham R, Weekes D, Alamshah A, Butler L, Galanty Y, Pangon L, Kiuchi T, Ng T, Solomon E.

Nature. 2009 Dec 17;462(7275):886-90. doi: 10.1038/nature08593.


Integrating receptor signal inputs that influence small Rho GTPase activation dynamics at the immunological synapse.

Makrogianneli K, Carlin LM, Keppler MD, Matthews DR, Ofo E, Coolen A, Ameer-Beg SM, Barber PR, Vojnovic B, Ng T.

Mol Cell Biol. 2009 Jun;29(11):2997-3006. doi: 10.1128/MCB.01008-08. Epub 2009 Mar 23.


Stabilized integrin-targeting ternary LPD (lipopolyplex) vectors for gene delivery designed to disassemble within the target cell.

Mustapa MF, Grosse SM, Kudsiova L, Elbs M, Raiber EA, Wong JB, Brain AP, Armer HE, Warley A, Keppler M, Ng T, Lawrence MJ, Hart SL, Hailes HC, Tabor AB.

Bioconjug Chem. 2009 Mar 18;20(3):518-32. doi: 10.1021/bc800450r.


satFRET: estimation of Förster resonance energy transfer by acceptor saturation.

Beutler M, Makrogianneli K, Vermeij RJ, Keppler M, Ng T, Jovin TM, Heintzmann R.

Eur Biophys J. 2008 Nov;38(1):69-82. doi: 10.1007/s00249-008-0361-5. Epub 2008 Sep 4.


An active Src kinase-beta-actin association is linked to actin dynamics at the periphery of colon cancer cells.

Avizienyte E, Keppler M, Sandilands E, Brunton VG, Winder SJ, Ng T, Frame MC.

Exp Cell Res. 2007 Sep 10;313(15):3175-88. Epub 2007 May 24.


HS1-associated protein X-1 regulates carcinoma cell migration and invasion via clathrin-mediated endocytosis of integrin alphavbeta6.

Ramsay AG, Keppler MD, Jazayeri M, Thomas GJ, Parsons M, Violette S, Weinreb P, Hart IR, Marshall JF.

Cancer Res. 2007 Jun 1;67(11):5275-84.


Activated ezrin promotes cell migration through recruitment of the GEF Dbl to lipid rafts and preferential downstream activation of Cdc42.

Prag S, Parsons M, Keppler MD, Ameer-Beg SM, Barber P, Hunt J, Beavil AJ, Calvert R, Arpin M, Vojnovic B, Ng T.

Mol Biol Cell. 2007 Aug;18(8):2935-48. Epub 2007 May 30.


Acupuncture for hot flashes: a randomized, sham-controlled clinical study.

Vincent A, Barton DL, Mandrekar JN, Cha SS, Zais T, Wahner-Roedler DL, Keppler MA, Kreitzer MJ, Loprinzi C.

Menopause. 2007 Jan-Feb;14(1):45-52.


Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells.

Parsons M, Monypenny J, Ameer-Beg SM, Millard TH, Machesky LM, Peter M, Keppler MD, Schiavo G, Watson R, Chernoff J, Zicha D, Vojnovic B, Ng T.

Mol Cell Biol. 2005 Mar;25(5):1680-95.


Multiphoton-FLIM quantification of the EGFP-mRFP1 FRET pair for localization of membrane receptor-kinase interactions.

Peter M, Ameer-Beg SM, Hughes MK, Keppler MD, Prag S, Marsh M, Vojnovic B, Ng T.

Biophys J. 2005 Feb;88(2):1224-37. Epub 2004 Nov 5.


DNA sequence specificity of triplex-binding ligands.

Keppler MD, James PL, Neidle S, Brown T, Fox KR.

Eur J Biochem. 2003 Dec;270(24):4982-92.


Site-directed perturbation of protein kinase C- integrin interaction blocks carcinoma cell chemotaxis.

Parsons M, Keppler MD, Kline A, Messent A, Humphries MJ, Gilchrist R, Hart IR, Quittau-Prevostel C, Hughes WE, Parker PJ, Ng T.

Mol Cell Biol. 2002 Aug;22(16):5897-911.


Deactivation of regulatory proteins hnRNP A1 and A2 during SC-1 induced apoptosis.

Hermann R, Hensel F, Müller EC, Keppler M, Souto-Carneiro M, Brändlein S, Müller-Hermelink HK, Vollmers HP.

Hum Antibodies. 2001;10(2):83-90.


Stabilisation of TG- and AG-containing antiparallel DNA triplexes by triplex-binding ligands.

Keppler MD, Neidle S, Fox KR.

Nucleic Acids Res. 2001 May 1;29(9):1935-42.


DNA triple helix stabilisation by covalent attachment of a triplex-specific ligand.

Keppler MD, McKeen CM, Zegrocka O, Strekowski L, Brown T, Fox KR.

Biochim Biophys Acta. 1999 Oct 28;1447(2-3):137-45.


Stabilization of DNA triple helices by a series of mono- and disubstituted amidoanthraquinones.

Keppler MD, Read MA, Perry PJ, Trent JO, Jenkins TC, Reszka AP, Neidle S, Fox KR.

Eur J Biochem. 1999 Aug;263(3):817-25.


DNA triple helix stabilisation by a naphthylquinoline dimer.

Keppler M, Zegrocka O, Strekowski L, Fox KR.

FEBS Lett. 1999 Mar 26;447(2-3):223-6.


5-(1-propargylamino)-2'-deoxyuridine (UP): a novel thymidine analogue for generating DNA triplexes with increased stability.

Bijapur J, Keppler MD, Bergqvist S, Brown T, Fox KR.

Nucleic Acids Res. 1999 Apr 15;27(8):1802-9.


Business forms: interviewing potential plaintiff-clients.

Keppler ME.

Natl Med Leg J. 1992;3(4):1, 6-7. No abstract available.


Comparative evaluation of abnormal cytology, colposcopy and histopathology in preclinical cervical malignancy during pregnancy.

Bertini-Oliveira AM, Keppler MM, Luisi A, Tarico S, Delascio Lopes VL, Delascio D, Camano L.

Acta Cytol. 1982 Sep-Oct;26(5):636-44.


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