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Items: 24

1.

Synthesis and antihormonal properties of novel 11β-benzoxazole-substituted steroids.

Jin C, Fix SE, Kepler JA, Cook CE.

Bioorg Med Chem Lett. 2012 Feb 15;22(4):1705-8. doi: 10.1016/j.bmcl.2011.12.110. Epub 2011 Dec 30.

PMID:
22260770
2.

17beta-Nitro-5alpha-androstan-3alpha-ol and its 3beta-methyl derivative: neurosteroid analogs with potent anticonvulsant and anxiolytic activities.

Runyon SP, Orr M, Navarro HA, Kepler JA, Rogawski MA, Kaminski RM, Cook CE.

Eur J Pharmacol. 2009 Sep 1;617(1-3):68-73. doi: 10.1016/j.ejphar.2009.06.052. Epub 2009 Jul 2.

3.

Synthesis and identification of novel 11beta-aryl-4',5'-dihydrospiro[estra-4,9-diene-17beta,4'-oxazole] analogs with dissociated antiprogesterone activities.

Jin C, Manikumar G, Kepler JA, Cook CE, Allan GF, Kiddoe M, Bhattacharjee S, Linton O, Lundeen SG, Sui Z.

Bioorg Med Chem Lett. 2007 Nov 1;17(21):5754-7. Epub 2007 Aug 29.

PMID:
17855092
4.
5.
6.

Direct photoaffinity labeling by dolastatin 10 of the amino-terminal peptide of beta-tubulin containing cysteine 12.

Bai R, Covell DG, Taylor GF, Kepler JA, Copeland TD, Nguyen NY, Pettit GR, Hamel E.

J Biol Chem. 2004 Jul 16;279(29):30731-40. Epub 2004 Apr 29.

8.

Sustained intracellular retention of dolastatin 10 causes its potent antimitotic activity.

Verdier-Pinard P, Kepler JA, Pettit GR, Hamel E.

Mol Pharmacol. 2000 Jan;57(1):180-7.

PMID:
10617693
9.

RTI-352: a 3 alpha analogue of RTI-55 as an in vivo dopamine transporter binding ligand.

Zhan Y, Saindane AM, Scheffel U, Carroll FI, Holmquist CR, Kepler JA, Taylor GF, Kuhar MJ.

Synapse. 1997 Apr;25(4):389-92. No abstract available.

PMID:
9097398
11.

In vivo labeling of neuronal nicotinic acetylcholine receptors with radiolabeled isomers of norchloroepibatidine.

Scheffel U, Taylor GF, Kepler JA, Carroll FI, Kuhar MJ.

Neuroreport. 1995 Dec 15;6(18):2483-8.

PMID:
8741747
12.

The spongistatins, potently cytotoxic inhibitors of tubulin polymerization, bind in a distinct region of the vinca domain.

Bai R, Taylor GF, Cichacz ZA, Herald CL, Kepler JA, Pettit GR, Hamel E.

Biochemistry. 1995 Aug 1;34(30):9714-21.

PMID:
7626642
13.

Interaction of dolastatin 10 with tubulin: induction of aggregation and binding and dissociation reactions.

Bai R, Taylor GF, Schmidt JM, Williams MD, Kepler JA, Pettit GR, Hamel E.

Mol Pharmacol. 1995 May;47(5):965-76.

PMID:
7746283
14.

Peptide derivatives of primaquine as potential antimalarial agents.

Philip A, Kepler JA, Johnson BH, Carroll FI.

J Med Chem. 1988 Apr;31(4):870-4.

PMID:
3280798
15.

1,2,4-Trioxanes as potential antimalarial agents.

Kepler JA, Philip A, Lee YW, Morey MC, Carroll FI.

J Med Chem. 1988 Apr;31(4):713-6.

PMID:
3280797
16.

Endoperoxides as potential antimalarial agents.

Kepler JA, Philip A, Lee YW, Musallam HA, Carroll FI.

J Med Chem. 1987 Aug;30(8):1505-9.

PMID:
3302259
17.

Enzymatic synthesis of a false cholinergic neurotransmitter: diethylaminoethyl acetate as a muscarinic agonist analog of acetylcholine.

Miura GA, Chiang PK, Gordon RK, Doctor BP, Twine CE, Philip A, Kepler JA, Carroll FI.

Gen Pharmacol. 1986;17(4):477-80.

PMID:
2875921
18.

Caffeine in plasma and saliva by a radioimmunoassay procedure.

Cook CE, Tallent CR, Amerson EW, Myers MW, Kepler JA, Taylor GF, Christensen HD.

J Pharmacol Exp Ther. 1976 Dec;199(3):679-86.

PMID:
1033273
19.

Carbon-13 nuclear magnetic resonance spectra of morphine alkaloids.

Carroll FI, Moreland CG, Brine GA, Kepler JA.

J Org Chem. 1976 Mar 19;41(6):996-1001. No abstract available.

PMID:
1255287
20.

Theophylline radioimmunoassay: synthesis of antigen and characterization of antiserum.

Cook CE, Twine ME, Myers M, Amerson E, Kepler JA, Taylor GF.

Res Commun Chem Pathol Pharmacol. 1976 Mar;13(3):497-505.

PMID:
935638
21.

Antiserum to diphenylhydantoin: preparation and characterization.

Cook CE, Kepler JA, Christensen HD.

Res Commun Chem Pathol Pharmacol. 1973 May;5(3):767-74. No abstract available.

PMID:
4701269
22.

The preparation of stereospecific tritium-labeled reduced nicotinamide adenine dinucleotide phosphate.

Freudenthal RI, Kepler JA, Cook CE.

Anal Biochem. 1973 Feb;51(2):632-6. No abstract available.

PMID:
4144737
23.

Plant antitumor agents. IX. The total synthesis of dl-camptothecin.

Wani MC, Campbell HF, Brine GA, Kepler JA, Wall ME, Levine SG.

J Am Chem Soc. 1972 May 17;94(10):3631-2. No abstract available.

PMID:
5032964
24.

Plant antitumor agents. IV. An approach toward the synthesis of camptothecin.

Kepler JA, Wani MC, McNaull JN, Wall ME, Levine SG.

J Org Chem. 1969 Dec;34(12):3853-8. No abstract available.

PMID:
5357525

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