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Items: 1 to 50 of 64

1.

Loss of dihydrotestosterone-inactivation activity promotes prostate cancer castration resistance detectable by functional imaging.

Zhu Z, Chung YM, Sergeeva O, Kepe V, Berk M, Li J, Ko HK, Li Z, Petro M, DiFilippo FP, Lee Z, Sharifi N.

J Biol Chem. 2018 Nov 16;293(46):17829-17837. doi: 10.1074/jbc.RA118.004846. Epub 2018 Sep 27.

PMID:
30262668
2.

Intestinal absorption of glucose in mice as determined by positron emission tomography.

Sala-Rabanal M, Ghezzi C, Hirayama BA, Kepe V, Liu J, Barrio JR, Wright EM.

J Physiol. 2018 Jul;596(13):2473-2489. doi: 10.1113/JP275934. Epub 2018 Jun 5.

3.

Positron emission tomography of sodium glucose cotransport activity in high grade astrocytomas.

Kepe V, Scafoglio C, Liu J, Yong WH, Bergsneider M, Huang SC, Barrio JR, Wright EM.

J Neurooncol. 2018 Jul;138(3):557-569. doi: 10.1007/s11060-018-2823-7. Epub 2018 Mar 10.

4.

Design, Syntheses, and in Vitro Evaluation of New Fluorine-18 Radiolabeled Tau-Labeling Molecular Probes.

Rejc L, Šmid L, Kepe V, Podlipnik Č, Golobič A, Bresjanac M, Barrio JR, Petrič A, Košmrlj J.

J Med Chem. 2017 Nov 9;60(21):8741-8757. doi: 10.1021/acs.jmedchem.7b00764. Epub 2017 Oct 2.

PMID:
28921979
5.

A semi-automated workflow solution for multimodal neuroimaging: application to patients with traumatic brain injury.

Wong KP, Bergsneider M, Glenn TC, Kepe V, Barrio JR, Hovda DA, Vespa PM, Huang SC.

Brain Inform. 2016 Mar;3(1):1-15. Epub 2015 Dec 1.

6.

Dapagliflozin Binds Specifically to Sodium-Glucose Cotransporter 2 in the Proximal Renal Tubule.

Ghezzi C, Yu AS, Hirayama BA, Kepe V, Liu J, Scafoglio C, Powell DR, Huang SC, Satyamurthy N, Barrio JR, Wright EM.

J Am Soc Nephrol. 2017 Mar;28(3):802-810. doi: 10.1681/ASN.2016050510. Epub 2016 Sep 12.

7.

A semi-automated workflow solution for multimodal neuroimaging: application to patients with traumatic brain injury.

Wong KP, Bergsneider M, Glenn TC, Kepe V, Barrio JR, Hovda DA, Vespa PM, Huang SC.

Brain Inform. 2016;3:1-15. Epub 2015 Dec 1.

8.

Revisiting the physiological roles of SGLTs and GLUTs using positron emission tomography in mice.

Sala-Rabanal M, Hirayama BA, Ghezzi C, Liu J, Huang SC, Kepe V, Koepsell H, Yu A, Powell DR, Thorens B, Wright EM, Barrio JR.

J Physiol. 2016 Aug 1;594(15):4425-38. doi: 10.1113/JP271904. Epub 2016 May 10.

9.

Functional expression of sodium-glucose transporters in cancer.

Scafoglio C, Hirayama BA, Kepe V, Liu J, Ghezzi C, Satyamurthy N, Moatamed NA, Huang J, Koepsell H, Barrio JR, Wright EM.

Proc Natl Acad Sci U S A. 2015 Jul 28;112(30):E4111-9. doi: 10.1073/pnas.1511698112. Epub 2015 Jul 13.

10.

In vivo characterization of chronic traumatic encephalopathy using [F-18]FDDNP PET brain imaging.

Barrio JR, Small GW, Wong KP, Huang SC, Liu J, Merrill DA, Giza CC, Fitzsimmons RP, Omalu B, Bailes J, Kepe V.

Proc Natl Acad Sci U S A. 2015 Apr 21;112(16):E2039-47. doi: 10.1073/pnas.1409952112. Epub 2015 Apr 6. Erratum in: Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):E2981.

11.

Automated movement correction for dynamic PET/CT images: evaluation with phantom and patient data.

Ye H, Wong KP, Wardak M, Dahlbom M, Kepe V, Barrio JR, Nelson LD, Small GW, Huang SC.

PLoS One. 2014 Aug 11;9(8):e103745. doi: 10.1371/journal.pone.0103745. eCollection 2014.

12.

A novel PSEN1 mutation (I238M) associated with early-onset Alzheimer's disease in an African-American woman.

Ting SK, Benzinger T, Kepe V, Fagan A, Coppola G, Porter V, Hecimovic S, Chakraverty S, Alvarez-Retuerto AI, Goate A, Ringman JM.

J Alzheimers Dis. 2014;40(2):271-5. doi: 10.3233/JAD-131844.

13.

Cerebral amyloid PET imaging in Alzheimer's disease.

Jack CR Jr, Barrio JR, Kepe V.

Acta Neuropathol. 2013 Nov;126(5):643-57. doi: 10.1007/s00401-013-1185-7. Epub 2013 Oct 8. Review.

14.

Amyloid PET Imaging: MCI and AD.

Kepe V.

PET Clin. 2013 Oct;8(4):431-45. doi: 10.1016/j.cpet.2013.08.002. Epub 2013 Oct 1.

PMID:
27156471
15.

Amyloid-β positron emission tomography imaging probes: a critical review.

Kepe V, Moghbel MC, Långström B, Zaidi H, Vinters HV, Huang SC, Satyamurthy N, Doudet D, Mishani E, Cohen RM, Høilund-Carlsen PF, Alavi A, Barrio JR.

J Alzheimers Dis. 2013;36(4):613-31. doi: 10.3233/JAD-130485. Review.

16.

PET imaging of neuropathology in tauopathies: progressive supranuclear palsy.

Kepe V, Bordelon Y, Boxer A, Huang SC, Liu J, Thiede FC, Mazziotta JC, Mendez MF, Donoghue N, Small GW, Barrio JR.

J Alzheimers Dis. 2013;36(1):145-53. doi: 10.3233/JAD-130032.

17.

A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss.

Cohen RM, Rezai-Zadeh K, Weitz TM, Rentsendorj A, Gate D, Spivak I, Bholat Y, Vasilevko V, Glabe CG, Breunig JJ, Rakic P, Davtyan H, Agadjanyan MG, Kepe V, Barrio JR, Bannykh S, Szekely CA, Pechnick RN, Town T.

J Neurosci. 2013 Apr 10;33(15):6245-56. doi: 10.1523/JNEUROSCI.3672-12.2013.

18.

Postmortem 3-D brain hemisphere cortical tau and amyloid-β pathology mapping and quantification as a validation method of neuropathology imaging.

Smid LM, Kepe V, Vinters HV, Bresjanac M, Toyokuni T, Satyamurthy N, Wong KP, Huang SC, Silverman DH, Miller K, Small GW, Barrio JR.

J Alzheimers Dis. 2013;36(2):261-74. doi: 10.3233/JAD-122434.

19.

Vascular risk and FDDNP-PET influence cognitive performance.

Merrill DA, Siddarth P, Kepe V, Raja PV, Saito N, Ercoli LM, Miller KJ, Lavretsky H, Bookheimer SY, Barrio JR, Small GW.

J Alzheimers Dis. 2013;35(1):147-57. doi: 10.3233/JAD-121903.

20.

PET scanning of brain tau in retired national football league players: preliminary findings.

Small GW, Kepe V, Siddarth P, Ercoli LM, Merrill DA, Donoghue N, Bookheimer SY, Martinez J, Omalu B, Bailes J, Barrio JR.

Am J Geriatr Psychiatry. 2013 Feb;21(2):138-44. doi: 10.1016/j.jagp.2012.11.019. Epub 2013 Jan 22.

PMID:
23343487
21.

Regional distribution of SGLT activity in rat brain in vivo.

Yu AS, Hirayama BA, Timbol G, Liu J, Diez-Sampedro A, Kepe V, Satyamurthy N, Huang SC, Wright EM, Barrio JR.

Am J Physiol Cell Physiol. 2013 Feb 1;304(3):C240-7. doi: 10.1152/ajpcell.00317.2012. Epub 2012 Nov 14.

22.

Dicyanovinylnaphthalenes for neuroimaging of amyloids and relationships of electronic structures and geometries to binding affinities.

Petric A, Johnson SA, Pham HV, Li Y, Ceh S, Golobic A, Agdeppa ED, Timbol G, Liu J, Keum G, Satyamurthy N, Kepe V, Houk KN, Barrio JR.

Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16492-7. doi: 10.1073/pnas.1214134109. Epub 2012 Sep 25. Erratum in: Proc Natl Acad Sci U S A. 2013 Mar 26;110(13):5269.

23.

Automated VOI Analysis in FDDNP PET Using Structural Warping: Validation through Classification of Alzheimer's Disease Patients.

Wilks MQ, Protas H, Wardak M, Kepe V, Small GW, Barrio JR, Huang SC.

Int J Alzheimers Dis. 2012;2012:512069. doi: 10.1155/2012/512069. Epub 2012 Mar 1.

24.

Prediction of cognitive decline based on hemispheric cortical surface maps of FDDNP PET.

Protas HD, Kepe V, Hayashi KM, Klunder AD, Braskie MN, Ercoli L, Siddarth P, Bookheimer SY, Thompson PM, Small GW, Barrio JR, Huang SC.

Neuroimage. 2012 Jul 16;61(4):749-60. doi: 10.1016/j.neuroimage.2012.02.056. Epub 2012 Feb 28.

25.

Assessment of dementia risk in aging adults using both FDG-PET and FDDNP-PET imaging.

Ercoli LM, Small GW, Siddarth P, Kepe V, Huang SC, Miller KJ, Lavretsky H, Bookheimer SY, Barrio JR, Silverman DH.

Int J Geriatr Psychiatry. 2012 Oct;27(10):1017-27. doi: 10.1002/gps.2816. Epub 2012 Mar 1.

26.

Self-reported memory impairment and brain PET of amyloid and tau in middle-aged and older adults without dementia.

Merrill DA, Siddarth P, Saito NY, Ercoli LM, Burggren AC, Kepe V, Lavretsky H, Miller KJ, Kim J, Huang SC, Bookheimer SY, Barrio JR, Small GW.

Int Psychogeriatr. 2012 Jul;24(7):1076-84. doi: 10.1017/S1041610212000051. Epub 2012 Feb 16.

27.

Prediction of cognitive decline by positron emission tomography of brain amyloid and tau.

Small GW, Siddarth P, Kepe V, Ercoli LM, Burggren AC, Bookheimer SY, Miller KJ, Kim J, Lavretsky H, Huang SC, Barrio JR.

Arch Neurol. 2012 Feb;69(2):215-22. doi: 10.1001/archneurol.2011.559.

28.

Comparative evaluation of Logan and relative-equilibrium graphical methods for parametric imaging of dynamic [18F]FDDNP PET determinations.

Wong KP, Kepe V, Dahlbom M, Satyamurthy N, Small GW, Barrio JR, Huang SC.

Neuroimage. 2012 Mar;60(1):241-51. doi: 10.1016/j.neuroimage.2011.12.014. Epub 2011 Dec 16.

29.

Protein binding in patients with late-life depression.

Kumar A, Kepe V, Barrio JR, Siddarth P, Manoukian V, Elderkin-Thompson V, Small GW.

Arch Gen Psychiatry. 2011 Nov;68(11):1143-50. doi: 10.1001/archgenpsychiatry.2011.122.

30.

The merits of FDDNP-PET imaging in Alzheimer's disease.

Shin J, Kepe V, Barrio JR, Small GW.

J Alzheimers Dis. 2011;26 Suppl 3:135-45. doi: 10.3233/JAD-2011-0008. Review.

PMID:
21971458
31.

Structural selectivity of human SGLT inhibitors.

Hummel CS, Lu C, Liu J, Ghezzi C, Hirayama BA, Loo DD, Kepe V, Barrio JR, Wright EM.

Am J Physiol Cell Physiol. 2012 Jan 15;302(2):C373-82. doi: 10.1152/ajpcell.00328.2011. Epub 2011 Sep 21.

32.

Positron emission tomography of brain β-amyloid and τ levels in adults with Down syndrome.

Nelson LD, Siddarth P, Kepe V, Scheibel KE, Huang SC, Barrio JR, Small GW.

Arch Neurol. 2011 Jun;68(6):768-74. doi: 10.1001/archneurol.2011.104.

33.

Multimodal Imaging of Alzheimer Pathophysiology in the Brain's Default Mode Network.

Shin J, Kepe V, Small GW, Phelps ME, Barrio JR.

Int J Alzheimers Dis. 2011;2011:687945. doi: 10.4061/2011/687945. Epub 2011 Apr 19.

34.

[F-18]FDDNP microPET imaging correlates with brain Aβ burden in a transgenic rat model of Alzheimer disease: effects of aging, in vivo blockade, and anti-Aβ antibody treatment.

Teng E, Kepe V, Frautschy SA, Liu J, Satyamurthy N, Yang F, Chen PP, Cole GB, Jones MR, Huang SC, Flood DG, Trusko SP, Small GW, Cole GM, Barrio JR.

Neurobiol Dis. 2011 Sep;43(3):565-75. doi: 10.1016/j.nbd.2011.05.003. Epub 2011 May 13.

35.

Biochemical, neuropathological, and neuroimaging characteristics of early-onset Alzheimer's disease due to a novel PSEN1 mutation.

Ringman JM, Gylys KH, Medina LD, Fox M, Kepe V, Flores DL, Apostolova LG, Barrio JR, Small G, Silverman DH, Siu E, Cederbaum S, Hecimovic S, Malnar M, Chakraverty S, Goate AM, Bird TD, Leverenz JB.

Neurosci Lett. 2011 Jan 10;487(3):287-92. doi: 10.1016/j.neulet.2010.10.039. Epub 2010 Nov 19. Erratum in: Neurosci Lett. 2011 Mar 17;491(2):163.

36.

Functional expression of SGLTs in rat brain.

Yu AS, Hirayama BA, Timbol G, Liu J, Basarah E, Kepe V, Satyamurthy N, Huang SC, Wright EM, Barrio JR.

Am J Physiol Cell Physiol. 2010 Dec;299(6):C1277-84. doi: 10.1152/ajpcell.00296.2010. Epub 2010 Sep 8.

37.

Specific estrogen sulfotransferase (SULT1E1) substrates and molecular imaging probe candidates.

Cole GB, Keum G, Liu J, Small GW, Satyamurthy N, Kepe V, Barrio JR.

Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6222-7. doi: 10.1073/pnas.0914904107. Epub 2010 Mar 19.

38.

Movement correction method for human brain PET images: application to quantitative analysis of dynamic 18F-FDDNP scans.

Wardak M, Wong KP, Shao W, Dahlbom M, Kepe V, Satyamurthy N, Small GW, Barrio JR, Huang SC.

J Nucl Med. 2010 Feb;51(2):210-8. doi: 10.2967/jnumed.109.063701. Epub 2010 Jan 15.

39.

Quantitative analysis of [18F]FDDNP PET using subcortical white matter as reference region.

Wong KP, Wardak M, Shao W, Dahlbom M, Kepe V, Liu J, Satyamurthy N, Small GW, Barrio JR, Huang SC.

Eur J Nucl Med Mol Imaging. 2010 Mar;37(3):575-88. doi: 10.1007/s00259-009-1293-8. Epub 2009 Oct 31.

40.

PET of brain prion protein amyloid in Gerstmann-Sträussler-Scheinker disease.

Kepe V, Ghetti B, Farlow MR, Bresjanac M, Miller K, Huang SC, Wong KP, Murrell JR, Piccardo P, Epperson F, Repovs G, Smid LM, Petric A, Siddarth P, Liu J, Satyamurthy N, Small GW, Barrio JR.

Brain Pathol. 2010 Mar;20(2):419-30. doi: 10.1111/j.1750-3639.2009.00306.x. Epub 2009 Jun 9.

PMID:
19725833
41.

FDDNP binding using MR derived cortical surface maps.

Protas HD, Huang SC, Kepe V, Hayashi K, Klunder A, Braskie MN, Ercoli L, Bookheimer S, Thompson PM, Small GW, Barrio JR.

Neuroimage. 2010 Jan 1;49(1):240-8. doi: 10.1016/j.neuroimage.2009.08.035. Epub 2009 Aug 22.

42.

Depression and anxiety symptoms are associated with cerebral FDDNP-PET binding in middle-aged and older nondemented adults.

Lavretsky H, Siddarth P, Kepe V, Ercoli LM, Miller KJ, Burggren AC, Bookheimer SY, Huang SC, Barrio JR, Small GW.

Am J Geriatr Psychiatry. 2009 Jun;17(6):493-502.

43.

Differential FDDNP PET patterns in nondemented middle-aged and older adults.

Ercoli LM, Siddarth P, Kepe V, Miller KJ, Huang SC, Cole GM, Lavretsky H, Bookheimer SY, Kim J, Phelps ME, Barrio JR, Small GW.

Am J Geriatr Psychiatry. 2009 May;17(5):397-406. doi: 10.1097/JGP.0b013e318198750b.

44.

Dissecting molecular mechanisms in the living brain of dementia patients.

Barrio JR, Satyamurthy N, Huang SC, Petric A, Small GW, Kepe V.

Acc Chem Res. 2009 Jul 21;42(7):842-50. doi: 10.1021/ar800189x.

PMID:
19281227
45.

Influence of cognitive status, age, and APOE-4 genetic risk on brain FDDNP positron-emission tomography imaging in persons without dementia.

Small GW, Siddarth P, Burggren AC, Kepe V, Ercoli LM, Miller KJ, Lavretsky H, Thompson PM, Cole GM, Huang SC, Phelps ME, Bookheimer SY, Barrio JR.

Arch Gen Psychiatry. 2009 Jan;66(1):81-7. doi: 10.1001/archgenpsychiatry.2008.516.

46.

Plaque and tangle imaging and cognition in normal aging and Alzheimer's disease.

Braskie MN, Klunder AD, Hayashi KM, Protas H, Kepe V, Miller KJ, Huang SC, Barrio JR, Ercoli LM, Siddarth P, Satyamurthy N, Liu J, Toga AW, Bookheimer SY, Small GW, Thompson PM.

Neurobiol Aging. 2010 Oct;31(10):1669-78. doi: 10.1016/j.neurobiolaging.2008.09.012. Epub 2008 Nov 11.

47.

Current and future uses of neuroimaging for cognitively impaired patients.

Small GW, Bookheimer SY, Thompson PM, Cole GM, Huang SC, Kepe V, Barrio JR.

Lancet Neurol. 2008 Feb;7(2):161-72. doi: 10.1016/S1474-4422(08)70019-X. Review.

48.

Amyloid and tau imaging, neuronal losses and function in mild cognitive impairment.

Barrio JR, Kepe V, Satyamurthy N, Huang SC, Small G.

J Nutr Health Aging. 2008 Jan;12(1):61S-5S.

PMID:
18165848
49.

Flurbiprofen derivatives in Alzheimer's disease: synthesis, pharmacokinetic and biological assessment of lipoamino acid prodrugs.

Pignatello R, Pantò V, Salmaso S, Bersani S, Pistarà V, Kepe V, Barrio JR, Puglisi G.

Bioconjug Chem. 2008 Jan;19(1):349-57. Epub 2007 Dec 12.

PMID:
18072715
50.

Mood, cognition and in vivo protein imaging: the emerging nexus in clinical neuroscience.

Kumar A, Ajilore O, Kepe V, Barrio JR, Small G.

Int J Geriatr Psychiatry. 2008 Jun;23(6):555-63. Review.

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