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Items: 1 to 50 of 71

1.

p53 and K-ras mutations in lung tissues and sputum samples of individuals exposed to smoky coal emissions in Xuan Wei County, China.

Keohavong P, Lan Q, Gao W.

Mutat Res Genet Toxicol Environ Mutagen. 2018 May - Jun;829-830:70-74. doi: 10.1016/j.mrgentox.2018.03.010. Epub 2018 Mar 30.

PMID:
29704996
2.

Sequence-dependent cleavage of mismatched DNA by Ban I restriction endonuclease.

Gao W, Zhu D, Keohavong P.

J Mol Recognit. 2017 Oct;30(10). doi: 10.1002/jmr.2638. Epub 2017 May 4.

PMID:
28470891
3.

KRAS and TP53 mutations in bronchoscopy samples from former lung cancer patients.

Gao W, Jin J, Yin J, Land S, Gaither-Davis A, Christie N, Luketich JD, Siegfried JM, Keohavong P.

Mol Carcinog. 2017 Feb;56(2):381-388. doi: 10.1002/mc.22501. Epub 2016 Jun 6.

PMID:
27182622
4.

Overexpression of CRM1: A Characteristic Feature in a Transformed Phenotype of Lung Carcinogenesis and a Molecular Target for Lung Cancer Adjuvant Therapy.

Gao W, Lu C, Chen L, Keohavong P.

J Thorac Oncol. 2015 May;10(5):815-25. doi: 10.1097/JTO.0000000000000485.

5.

Detection of point mutations of K-ras oncogene and p53 tumor-suppressor gene in sputum samples.

Gao W, Keohavong P.

Methods Mol Biol. 2014;1105:325-44. doi: 10.1007/978-1-62703-739-6_26.

PMID:
24623240
6.

Molecular analysis of mutations in the human HPRT gene.

Keohavong P, Xi L, Grant SG.

Methods Mol Biol. 2014;1105:291-301. doi: 10.1007/978-1-62703-739-6_23.

PMID:
24623237
7.

Long-term effects of carbon containing engineered nanomaterials and asbestos in the lung: one year postexposure comparisons.

Shvedova AA, Yanamala N, Kisin ER, Tkach AV, Murray AR, Hubbs A, Chirila MM, Keohavong P, Sycheva LP, Kagan VE, Castranova V.

Am J Physiol Lung Cell Mol Physiol. 2014 Jan;306(2):L170-82. doi: 10.1152/ajplung.00167.2013. Epub 2013 Nov 8.

8.

Prevention of tobacco carcinogen-induced lung cancer in female mice using antiestrogens.

Stabile LP, Rothstein ME, Cunningham DE, Land SR, Dacic S, Keohavong P, Siegfried JM.

Carcinogenesis. 2012 Nov;33(11):2181-9. doi: 10.1093/carcin/bgs260. Epub 2012 Aug 2. Erratum in: Carcinogenesis. 2013 Jun;34(6):1411.

9.

K-ras mutations in lung tumors from NNK-treated mice with lipopolysaccharide-elicited lung inflammation.

Keohavong P, Kahkonen B, Kinchington E, Yin J, Jin J, Liu X, Siegfried JM, DI YP.

Anticancer Res. 2011 Sep;31(9):2877-82.

PMID:
21868532
10.

Targeting of Both the c-Met and EGFR Pathways Results in Additive Inhibition of Lung Tumorigenesis in Transgenic Mice.

Stabile LP, Rothstein ME, Keohavong P, Lenzner D, Land SR, Gaither-Davis AL, Kim KJ, Kaminski N, Siegfried JM.

Cancers (Basel). 2010 Dec 1;2(4):2153-70. doi: 10.3390/cancers2042153.

11.

Genetic polymorphisms in the DNA repair genes XPD and XRCC1, p53 gene mutations and bladder cancer risk.

Gao W, Romkes M, Zhong S, Nukui T, Persad RA, Smith PJ, Branch R, Keohavong P.

Oncol Rep. 2010 Jul;24(1):257-62.

12.

Analysis of p53 mutations in histologically normal lung tissues and lung tumors from non-small cell lung cancer patients.

Gao W, Mady HH, Melhem MF, Keohavong P.

Mol Carcinog. 2009 Jul;48(7):633-41. doi: 10.1002/mc.20505.

PMID:
19072763
13.

Aberrant gene promoter methylation in sputum from individuals exposed to smoky coal emissions.

Liu Y, Lan Q, Shen M, Jin J, Mumford J, Ren D, Keohavong P.

Anticancer Res. 2008 Jul-Aug;28(4B):2061-6.

14.

Inhalation vs. aspiration of single-walled carbon nanotubes in C57BL/6 mice: inflammation, fibrosis, oxidative stress, and mutagenesis.

Shvedova AA, Kisin E, Murray AR, Johnson VJ, Gorelik O, Arepalli S, Hubbs AF, Mercer RR, Keohavong P, Sussman N, Jin J, Yin J, Stone S, Chen BT, Deye G, Maynard A, Castranova V, Baron PA, Kagan VE.

Am J Physiol Lung Cell Mol Physiol. 2008 Oct;295(4):L552-65. doi: 10.1152/ajplung.90287.2008. Epub 2008 Jul 25.

15.

Therapeutic targeting of human hepatocyte growth factor with a single neutralizing monoclonal antibody reduces lung tumorigenesis.

Stabile LP, Rothstein ME, Keohavong P, Jin J, Yin J, Land SR, Dacic S, Luong TM, Kim KJ, Dulak AM, Siegfried JM.

Mol Cancer Ther. 2008 Jul;7(7):1913-22. doi: 10.1158/1535-7163.MCT-07-2169.

16.

Promoter methylation of RASSF1A and DAPK and mutations of K-ras, p53, and EGFR in lung tumors from smokers and never-smokers.

Liu Y, Gao W, Siegfried JM, Weissfeld JL, Luketich JD, Keohavong P.

BMC Cancer. 2007 May 3;7:74.

17.

Mutation and polymorphism in the EGFR-TK domain associated with lung cancer.

Zhang W, Stabile LP, Keohavong P, Romkes M, Grandis JR, Traynor AM, Siegfried JM.

J Thorac Oncol. 2006 Sep;1(7):635-47.

18.

Polymorphisms in DNA repair genes XPD and XRCC1 and p53 mutations in lung carcinomas of never-smokers.

Gao WM, Romkes M, Siegfried JM, Luketich JD, Keohavong P.

Mol Carcinog. 2006 Nov;45(11):828-32.

PMID:
16865671
19.

Increased mutant frequencies in the HPRT gene locus of leukemia HL-60 cells treated with succinylacetone.

Zheng KC, Yalowich JC, Kagan VE, Keohavong P.

Cell Biol Toxicol. 2006 Sep;22(5):361-70. Epub 2006 Jul 11.

PMID:
16838078
20.
21.

Smoky coal exposure, NBS1 polymorphisms, p53 protein accumulation, and lung cancer risk in Xuan Wei, China.

Lan Q, Shen M, Berndt SI, Bonner MR, He X, Yeager M, Welch R, Keohavong P, Donahue M, Hainaut P, Chanock S.

Lung Cancer. 2005 Sep;49(3):317-23.

PMID:
15921821
22.

Polymorphisms in the DNA base excision repair genes APEX1 and XRCC1 and lung cancer risk in Xuan Wei, China.

Shen M, Berndt SI, Rothman N, Mumford JL, He X, Yeager M, Welch R, Chanock S, Keohavong P, Donahue M, Zheng T, Caporaso N, Lan Q.

Anticancer Res. 2005 Jan-Feb;25(1B):537-42.

23.

HPRT gene alterations in umbilical cord blood T-lymphocytes in newborns of mothers exposed to tobacco smoke during pregnancy.

Keohavong P, Xi L, Day RD, Zhang L, Grant SG, Day BW, Ness RB, Bigbee WL.

Mutat Res. 2005 May 2;572(1-2):156-66.

PMID:
15790499
24.

Detection of p53 and K-ras mutations in sputum of individuals exposed to smoky coal emissions in Xuan Wei County, China.

Keohavong P, Lan Q, Gao WM, Zheng KC, Mady HH, Melhem MF, Mumford JL.

Carcinogenesis. 2005 Feb;26(2):303-8. Epub 2004 Nov 25.

PMID:
15564291
25.

Analysis of K-RAS and P53 mutations in sputum samples.

Gao W, Keohavong P.

Methods Mol Biol. 2005;291:217-33.

PMID:
15502226
26.

Molecular analysis of mutations in the human HPRT gene.

Keohavong P, Xi L, Grant SG.

Methods Mol Biol. 2005;291:161-70.

PMID:
15502221
27.

Oxidative damage-related genes AKR1C3 and OGG1 modulate risks for lung cancer due to exposure to PAH-rich coal combustion emissions.

Lan Q, Mumford JL, Shen M, Demarini DM, Bonner MR, He X, Yeager M, Welch R, Chanock S, Tian L, Chapman RS, Zheng T, Keohavong P, Caporaso N, Rothman N.

Carcinogenesis. 2004 Nov;25(11):2177-81. Epub 2004 Jul 29.

PMID:
15284179
28.
29.

No association between the XPD 312, 751, or XRCC1 399 polymorphisms and K-ras gene mutation in smoking non-small-cell lung cancer.

Gao WM, Romkes M, Siegfried JM, Luketich JD, Keohavong P.

Cancer Epidemiol Biomarkers Prev. 2004 Apr;13(4):673-5. No abstract available.

30.

Detection of K-ras and p53 mutations in sputum samples of lung cancer patients using laser capture microdissection microscope and mutation analysis.

Keohavong P, Gao WM, Zheng KC, Mady H, Lan Q, Melhem M, Mumford J.

Anal Biochem. 2004 Jan 1;324(1):92-9.

PMID:
14654050
31.

Association of the DNA repair gene XPD Asp312Asn polymorphism with p53 gene mutations in tobacco-related non-small cell lung cancer.

Gao WM, Romkes M, Day RD, Siegfried JM, Luketich JD, Mady HH, Melhem MF, Keohavong P.

Carcinogenesis. 2003 Oct;24(10):1671-6. Epub 2003 Jul 4.

PMID:
12844488
32.

K-ras mutations in lung carcinomas from nonsmoking women exposed to unvented coal smoke in China.

Keohavong P, Lan Q, Gao WM, DeMarini DM, Mass MJ, Li XM, Roop BC, Weissfeld J, Tian D, Mumford JL.

Lung Cancer. 2003 Jul;41(1):21-7.

PMID:
12826308
33.

Comparison of K-ras gene mutations in tumour and sputum DNA of patients with lung cancer.

Zhang LF, Gao WM, Gealy R, Weissfeld J, Elder E, Whiteside TL, Keohavong P.

Biomarkers. 2003 Mar-Apr;8(2):156-61.

PMID:
12775500
34.
35.

Lung tumor KRAS and TP53 mutations in nonsmokers reflect exposure to PAH-rich coal combustion emissions.

DeMarini DM, Landi S, Tian D, Hanley NM, Li X, Hu F, Roop BC, Mass MJ, Keohavong P, Gao W, Olivier M, Hainaut P, Mumford JL.

Cancer Res. 2001 Sep 15;61(18):6679-81.

36.

Topographic analysis of K- ras mutations in histologically normal lung tissues and tumours of lung cancer patients.

Keohavong P, Mady HH, Gao WM, Siegfried JM, Luketich JD, Melhem MF.

Br J Cancer. 2001 Jul 20;85(2):235-41.

37.
38.

Comparison of mutations in the p53 and K-ras genes in lung carcinomas from smoking and nonsmoking women.

Gealy R, Zhang L, Siegfried JM, Luketich JD, Keohavong P.

Cancer Epidemiol Biomarkers Prev. 1999 Apr;8(4 Pt 1):297-302. Erratum in: Cancer Epidemiol Biomarkers Prev 2001 Dec;10(12):1309.

39.

Effects of bulky polycyclic aromatic hydrocarbon adducts on DNA replication by exonuclease-deficient T7 and T4 DNA polymerases.

Keohavong P, Shukla R, Melacrinos A, Day BW, Reha-Krantz L.

DNA Cell Biol. 1998 Jun;17(6):541-9.

PMID:
9655247
40.

Prognostic value of specific KRAS mutations in lung adenocarcinomas.

Siegfried JM, Gillespie AT, Mera R, Casey TJ, Keohavong P, Testa JR, Hunt JD.

Cancer Epidemiol Biomarkers Prev. 1997 Oct;6(10):841-7.

41.

K-ras gene mutations in normal colorectal tissues from K-ras mutation-positive colorectal cancer patients.

Zhu D, Keohavong P, Finkelstein SD, Swalsky P, Bakker A, Weissfeld J, Srivastava S, Whiteside TL.

Cancer Res. 1997 Jun 15;57(12):2485-92.

42.

Detection of infrequent and multiple K-ras mutations in human tumors and tumor-adjacent tissues.

Keohavong P, Zhu D, Whiteside TL, Swalsky P, Bakker A, Elder EM, Siegfried JM, Srivastava S, Finkelstein SD.

Anal Biochem. 1997 May 1;247(2):394-403.

PMID:
9177704
43.

Detection of low-fraction K-ras mutations in primary lung tumors using a sensitive method.

Keohavong P, Zhu D, Melacrinos AC, DeMichele MA, Weyant RJ, Luketich JD, Testa JR, Fedder M, Siegfried JM.

Int J Cancer. 1997 Apr 22;74(2):162-70.

44.

Taq-amplified fragments appear as doublets in denaturing gradient gels.

Zhu D, Zhou J, Keohavong P.

Anal Biochem. 1997 Jan 15;244(2):404-6. No abstract available.

PMID:
9025958
45.

Sporadic and Thorotrast-induced angiosarcomas of the liver manifest frequent and multiple point mutations in K-ras-2.

Przygodzki RM, Finkelstein SD, Keohavong P, Zhu D, Bakker A, Swalsky PA, Soini Y, Ishak KG, Bennett WP.

Lab Invest. 1997 Jan;76(1):153-9.

PMID:
9010458
47.

Detection of K-ras mutations in lung carcinomas: relationship to prognosis.

Keohavong P, DeMichele MA, Melacrinos AC, Landreneau RJ, Weyant RJ, Siegfried JM.

Clin Cancer Res. 1996 Feb;2(2):411-8.

48.

In vitro mutational spectrum of cyclopenta[cd]pyrene in the human HPRT gene.

Keohavong P, Melacrinos A, Shukla R.

Carcinogenesis. 1995 Apr;16(4):855-60.

PMID:
7728967
49.

Resolution and conservation of mismatches in DNA end joining.

Pfeiffer P, Thode S, Hancke J, Keohavong P, Thilly WG.

Mutagenesis. 1994 Nov;9(6):527-35.

PMID:
7854144
50.

Use of anti-TNF-alpha antiserum to investigate toxic alveolitis arising from cotton dust exposure.

Shvedova AA, Kramarik JA, Keohavong P, Chumakov KM, Karol MH.

Exp Lung Res. 1994 Jul-Aug;20(4):297-315.

PMID:
7988494

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