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Items: 1 to 50 of 171

1.

Patient Engagement Activities and Patient Experience: Are Patients With a History of Depression the Canary in the Coal Mine?

Shields MC, Singer J, Rosenthal M, Sato L, Keohane C, Janes M, Boulanger J, Martins N, Rabson B.

Med Care Res Rev. 2019 May 22:1077558719850705. doi: 10.1177/1077558719850705. [Epub ahead of print]

PMID:
31117918
2.

Essential thrombocythaemia treated with recombinant interferon: 'real world' United Kingdom referral centre experience.

Desterro J, McLornan DP, Curto Garcia N, O'Sullivan J, Alimam S, Keohane C, Woodley C, Francis Y, Kordasti S, Radia DH, Harrison CN.

Br J Haematol. 2019 May 15. doi: 10.1111/bjh.15968. [Epub ahead of print]

PMID:
31090926
3.

Role of Patient Safety Organizations in Improving Patient Safety.

Boulanger J, Keohane C, Yeats A.

Obstet Gynecol Clin North Am. 2019 Jun;46(2):257-267. doi: 10.1016/j.ogc.2019.02.001. Review.

PMID:
31056128
4.

A multicenter report on the natural history of myelodysplastic syndromes in very old patients (aged over 85 years).

McDonald LS, McCarthy P, Khan M, Hogan P, Kelleher E, Murphy PT, Quinn J, Desmond R, McHugh J, Strickland M, O'Connell E, Cahill M, Maung SW, Keohane C, O'Neill D, Ryan D, Mykytiv V, Enright H.

Leuk Lymphoma. 2019 May;60(5):1324-1327. doi: 10.1080/10428194.2018.1538513. Epub 2019 Jan 11. No abstract available.

PMID:
30632846
5.

Transcriptomic Profiling Suggests That Promysalin Alters the Metabolic Flux, Motility, and Iron Regulation in Pseudomonas putida KT2440.

Giglio KM, Keohane CE, Stodghill PV, Steele AD, Fetzer C, Sieber SA, Filiatrault MJ, Wuest WM.

ACS Infect Dis. 2018 Aug 10;4(8):1179-1187. doi: 10.1021/acsinfecdis.8b00041. Epub 2018 Jun 5.

PMID:
29801413
6.

A new class of synthetic retinoid antibiotics effective against bacterial persisters.

Kim W, Zhu W, Hendricks GL, Van Tyne D, Steele AD, Keohane CE, Fricke N, Conery AL, Shen S, Pan W, Lee K, Rajamuthiah R, Fuchs BB, Vlahovska PM, Wuest WM, Gilmore MS, Gao H, Ausubel FM, Mylonakis E.

Nature. 2018 Apr 5;556(7699):103-107. doi: 10.1038/nature26157. Epub 2018 Mar 28.

7.

DNA methylation-based classification of central nervous system tumours.

Capper D, Jones DTW, Sill M, Hovestadt V, Schrimpf D, Sturm D, Koelsche C, Sahm F, Chavez L, Reuss DE, Kratz A, Wefers AK, Huang K, Pajtler KW, Schweizer L, Stichel D, Olar A, Engel NW, Lindenberg K, Harter PN, Braczynski AK, Plate KH, Dohmen H, Garvalov BK, Coras R, Hölsken A, Hewer E, Bewerunge-Hudler M, Schick M, Fischer R, Beschorner R, Schittenhelm J, Staszewski O, Wani K, Varlet P, Pages M, Temming P, Lohmann D, Selt F, Witt H, Milde T, Witt O, Aronica E, Giangaspero F, Rushing E, Scheurlen W, Geisenberger C, Rodriguez FJ, Becker A, Preusser M, Haberler C, Bjerkvig R, Cryan J, Farrell M, Deckert M, Hench J, Frank S, Serrano J, Kannan K, Tsirigos A, Brück W, Hofer S, Brehmer S, Seiz-Rosenhagen M, Hänggi D, Hans V, Rozsnoki S, Hansford JR, Kohlhof P, Kristensen BW, Lechner M, Lopes B, Mawrin C, Ketter R, Kulozik A, Khatib Z, Heppner F, Koch A, Jouvet A, Keohane C, Mühleisen H, Mueller W, Pohl U, Prinz M, Benner A, Zapatka M, Gottardo NG, Driever PH, Kramm CM, Müller HL, Rutkowski S, von Hoff K, Frühwald MC, Gnekow A, Fleischhack G, Tippelt S, Calaminus G, Monoranu CM, Perry A, Jones C, Jacques TS, Radlwimmer B, Gessi M, Pietsch T, Schramm J, Schackert G, Westphal M, Reifenberger G, Wesseling P, Weller M, Collins VP, Blümcke I, Bendszus M, Debus J, Huang A, Jabado N, Northcott PA, Paulus W, Gajjar A, Robinson GW, Taylor MD, Jaunmuktane Z, Ryzhova M, Platten M, Unterberg A, Wick W, Karajannis MA, Mittelbronn M, Acker T, Hartmann C, Aldape K, Schüller U, Buslei R, Lichter P, Kool M, Herold-Mende C, Ellison DW, Hasselblatt M, Snuderl M, Brandner S, Korshunov A, von Deimling A, Pfister SM.

Nature. 2018 Mar 22;555(7697):469-474. doi: 10.1038/nature26000. Epub 2018 Mar 14.

8.

Partnering With a Medical Malpractice Insurer to Improve Patient Safety and Decrease Risk.

Keohane CA, Dwyer K, Boulanger J, Zigmont K, Babayan A, Cushing E, Walsh B.

J Perinat Neonatal Nurs. 2018 Jan/Mar;32(1):66-71. doi: 10.1097/JPN.0000000000000312.

PMID:
29373421
9.

Promysalin Elicits Species-Selective Inhibition of Pseudomonas aeruginosa by Targeting Succinate Dehydrogenase.

Keohane CE, Steele AD, Fetzer C, Khowsathit J, Van Tyne D, Moynié L, Gilmore MS, Karanicolas J, Sieber SA, Wuest WM.

J Am Chem Soc. 2018 Feb 7;140(5):1774-1782. doi: 10.1021/jacs.7b11212. Epub 2018 Jan 24.

10.

Missed Diagnosis of Cardiovascular Disease in Outpatient General Medicine: Insights from Malpractice Claims Data.

Quinn GR, Ranum D, Song E, Linets M, Keohane C, Riah H, Greenberg P.

Jt Comm J Qual Patient Saf. 2017 Oct;43(10):508-516. doi: 10.1016/j.jcjq.2017.05.001. Epub 2017 Jun 26.

11.

Effects of the I-PASS Nursing Handoff Bundle on communication quality and workflow.

Starmer AJ, Schnock KO, Lyons A, Hehn RS, Graham DA, Keohane C, Landrigan CP.

BMJ Qual Saf. 2017 Dec;26(12):949-957. doi: 10.1136/bmjqs-2016-006224. Epub 2017 Jul 5.

PMID:
28679836
12.

Randomized Trial of Reducing Ambulatory Malpractice and Safety Risk: Results of the Massachusetts PROMISES Project.

Schiff GD, Reyes Nieva H, Griswold P, Leydon N, Ling J, Federico F, Keohane C, Ellis BR, Foskett C, Orav EJ, Yoon C, Goldmann D, Weissman JS, Bates DW, Biondolillo M, Singer SJ.

Med Care. 2017 Aug;55(8):797-805. doi: 10.1097/MLR.0000000000000759.

13.

How Communication Among Members of the Health Care Team Affects Maternal Morbidity and Mortality.

Brennan RA, Keohane CA.

J Obstet Gynecol Neonatal Nurs. 2016 Nov - Dec;45(6):878-884. doi: 10.1016/j.jogn.2016.03.142. Epub 2016 Sep 16.

PMID:
27644071
14.

Perspective training to treat anger problems after brain injury: Two case studies.

Winegardner J, Keohane C, Prince L, Neumann D.

NeuroRehabilitation. 2016 Jun 18;39(1):153-62. doi: 10.3233/NRE-161347.

15.

Diverted Total Synthesis of Promysalin Analogs Demonstrates That an Iron-Binding Motif Is Responsible for Its Narrow-Spectrum Antibacterial Activity.

Steele AD, Keohane CE, Knouse KW, Rossiter SE, Williams SJ, Wuest WM.

J Am Chem Soc. 2016 May 11;138(18):5833-6. doi: 10.1021/jacs.6b03373. Epub 2016 Apr 28.

16.

Isolated Cerebellar Spindle Cell Pseudotumor Caused by Mycobacterium Avium-Intracellulare Complex in a Patient without AIDS.

Lim MS, Bermingham N, O'Broin C, Khalil A, Keohane C, Lim C.

World Neurosurg. 2016 Jun;90:703.e1-703.e3. doi: 10.1016/j.wneu.2016.02.082. Epub 2016 Feb 27.

PMID:
26926796
17.

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs.

Sturm D, Orr BA, Toprak UH, Hovestadt V, Jones DTW, Capper D, Sill M, Buchhalter I, Northcott PA, Leis I, Ryzhova M, Koelsche C, Pfaff E, Allen SJ, Balasubramanian G, Worst BC, Pajtler KW, Brabetz S, Johann PD, Sahm F, Reimand J, Mackay A, Carvalho DM, Remke M, Phillips JJ, Perry A, Cowdrey C, Drissi R, Fouladi M, Giangaspero F, Łastowska M, Grajkowska W, Scheurlen W, Pietsch T, Hagel C, Gojo J, Lötsch D, Berger W, Slavc I, Haberler C, Jouvet A, Holm S, Hofer S, Prinz M, Keohane C, Fried I, Mawrin C, Scheie D, Mobley BC, Schniederjan MJ, Santi M, Buccoliero AM, Dahiya S, Kramm CM, von Bueren AO, von Hoff K, Rutkowski S, Herold-Mende C, Frühwald MC, Milde T, Hasselblatt M, Wesseling P, Rößler J, Schüller U, Ebinger M, Schittenhelm J, Frank S, Grobholz R, Vajtai I, Hans V, Schneppenheim R, Zitterbart K, Collins VP, Aronica E, Varlet P, Puget S, Dufour C, Grill J, Figarella-Branger D, Wolter M, Schuhmann MU, Shalaby T, Grotzer M, van Meter T, Monoranu CM, Felsberg J, Reifenberger G, Snuderl M, Forrester LA, Koster J, Versteeg R, Volckmann R, van Sluis P, Wolf S, Mikkelsen T, Gajjar A, Aldape K, Moore AS, Taylor MD, Jones C, Jabado N, Karajannis MA, Eils R, Schlesner M, Lichter P, von Deimling A, Pfister SM, Ellison DW, Korshunov A, Kool M.

Cell. 2016 Feb 25;164(5):1060-1072. doi: 10.1016/j.cell.2016.01.015.

18.

The effects of JAK inhibitor therapy upon novel markers of thrombosis In myeloproliferative neoplasms.

Keohane C, McLornan DP, Sanchez K, Connor C, Radia D, Harrison CN.

Haematologica. 2015 Sep;100(9):e348-50. doi: 10.3324/haematol.2015.128918. Epub 2015 Jun 18. No abstract available.

19.

JAK inhibition induces silencing of T Helper cytokine secretion and a profound reduction in T regulatory cells.

Keohane C, Kordasti S, Seidl T, Perez Abellan P, Thomas NS, Harrison CN, McLornan DP, Mufti GJ.

Br J Haematol. 2015 Oct;171(1):60-73. doi: 10.1111/bjh.13519. Epub 2015 Jun 15.

PMID:
26075866
20.

Total synthesis and biological investigation of (-)-promysalin.

Steele AD, Knouse KW, Keohane CE, Wuest WM.

J Am Chem Soc. 2015 Jun 17;137(23):7314-7. doi: 10.1021/jacs.5b04767. Epub 2015 Jun 5.

PMID:
26024439
21.

"Unusual brain stone": heavily calcified primary neoplasm with some features suggestive of angiocentric glioma.

Sajjad J, Kaliaperumal C, Bermingham N, Marks C, Keohane C.

J Neurosurg. 2015 Nov;123(5):1256-60. doi: 10.3171/2014.11.JNS131158. Epub 2015 May 29.

PMID:
26024003
22.

Changes in medical errors after implementation of a handoff program.

Starmer AJ, Spector ND, Srivastava R, West DC, Rosenbluth G, Allen AD, Noble EL, Tse LL, Dalal AK, Keohane CA, Lipsitz SR, Rothschild JM, Wien MF, Yoon CS, Zigmont KR, Wilson KM, O'Toole JK, Solan LG, Aylor M, Bismilla Z, Coffey M, Mahant S, Blankenburg RL, Destino LA, Everhart JL, Patel SJ, Bale JF Jr, Spackman JB, Stevenson AT, Calaman S, Cole FS, Balmer DF, Hepps JH, Lopreiato JO, Yu CE, Sectish TC, Landrigan CP; I-PASS Study Group.

N Engl J Med. 2014 Nov 6;371(19):1803-12. doi: 10.1056/NEJMsa1405556.

23.

Combination therapy with ruxolitinib plus 5-azacytidine or continuous infusion of low dose cytarabine is feasible in patients with blast-phase myeloproliferative neoplasms.

Mwirigi A, Galli S, Keohane C, Raj K, Radia DH, Harrison CN, McLornan DP.

Br J Haematol. 2014 Dec;167(5):714-6. doi: 10.1111/bjh.13046. Epub 2014 Jul 22. No abstract available.

PMID:
25048366
24.

A novel approach to assess the spontaneous gastrointestinal bleeding risk of antithrombotic agents using Apc(min/+) mice.

Wei H, Shang J, Keohane C, Wang M, Li Q, Ni W, O'Neill K, Chintala M.

Thromb Haemost. 2014 Jun;111(6):1121-32. doi: 10.1160/TH13-11-0926. Epub 2014 Jan 16.

PMID:
24430131
25.

Somatic CALR mutations in myeloproliferative neoplasms with nonmutated JAK2.

Nangalia J, Massie CE, Baxter EJ, Nice FL, Gundem G, Wedge DC, Avezov E, Li J, Kollmann K, Kent DG, Aziz A, Godfrey AL, Hinton J, Martincorena I, Van Loo P, Jones AV, Guglielmelli P, Tarpey P, Harding HP, Fitzpatrick JD, Goudie CT, Ortmann CA, Loughran SJ, Raine K, Jones DR, Butler AP, Teague JW, O'Meara S, McLaren S, Bianchi M, Silber Y, Dimitropoulou D, Bloxham D, Mudie L, Maddison M, Robinson B, Keohane C, Maclean C, Hill K, Orchard K, Tauro S, Du MQ, Greaves M, Bowen D, Huntly BJP, Harrison CN, Cross NCP, Ron D, Vannucchi AM, Papaemmanuil E, Campbell PJ, Green AR.

N Engl J Med. 2013 Dec 19;369(25):2391-2405. doi: 10.1056/NEJMoa1312542. Epub 2013 Dec 10.

26.

Rates of medical errors and preventable adverse events among hospitalized children following implementation of a resident handoff bundle.

Starmer AJ, Sectish TC, Simon DW, Keohane C, McSweeney ME, Chung EY, Yoon CS, Lipsitz SR, Wassner AJ, Harper MB, Landrigan CP.

JAMA. 2013 Dec 4;310(21):2262-70. doi: 10.1001/jama.2013.281961.

PMID:
24302089
27.

The diagnosis and management of erythrocytosis.

Keohane C, McMullin MF, Harrison C.

BMJ. 2013 Nov 18;347:f6667. doi: 10.1136/bmj.f6667. Review. No abstract available.

PMID:
24246666
28.

Unrealized potential and residual consequences of electronic prescribing on pharmacy workflow in the outpatient pharmacy.

Nanji KC, Rothschild JM, Boehne JJ, Keohane CA, Ash JS, Poon EG.

J Am Med Inform Assoc. 2014 May-Jun;21(3):481-6. doi: 10.1136/amiajnl-2013-001839. Epub 2013 Oct 23.

29.

Genetic deletion and pharmacological inhibition of phosphodiesterase 10A protects mice from diet-induced obesity and insulin resistance.

Nawrocki AR, Rodriguez CG, Toolan DM, Price O, Henry M, Forrest G, Szeto D, Keohane CA, Pan Y, Smith KM, Raheem IT, Cox CD, Hwa J, Renger JJ, Smith SM.

Diabetes. 2014 Jan;63(1):300-11. doi: 10.2337/db13-0247. Epub 2013 Oct 7.

30.

Impact of vendor computerized physician order entry on patients with renal impairment in community hospitals.

Leung AA, Schiff G, Keohane C, Amato M, Simon SR, Cadet B, Coffey M, Kaufman N, Zimlichman E, Seger DL, Yoon C, Bates DW.

J Hosp Med. 2013 Oct;8(10):545-52. doi: 10.1002/jhm.2072.

PMID:
24101539
31.

Practical management of patients with myelofibrosis receiving ruxolitinib.

Harrison C, Mesa R, Ross D, Mead A, Keohane C, Gotlib J, Verstovsek S.

Expert Rev Hematol. 2013 Oct;6(5):511-23. doi: 10.1586/17474086.2013.827413. Epub 2013 Oct 2. Review.

PMID:
24083419
32.

Primary care closed claims experience of Massachusetts malpractice insurers.

Schiff GD, Puopolo AL, Huben-Kearney A, Yu W, Keohane C, McDonough P, Ellis BR, Bates DW, Biondolillo M.

JAMA Intern Med. 2013 Dec 9-23;173(22):2063-8. doi: 10.1001/jamainternmed.2013.11070.

PMID:
24081145
33.

Resolution of bone marrow fibrosis in a patient receiving JAK1/JAK2 inhibitor treatment with ruxolitinib.

Wilkins BS, Radia D, Woodley C, Farhi SE, Keohane C, Harrison CN.

Haematologica. 2013 Dec;98(12):1872-6. doi: 10.3324/haematol.2013.095109. Epub 2013 Sep 20.

34.

Health care-associated infections: a meta-analysis of costs and financial impact on the US health care system.

Zimlichman E, Henderson D, Tamir O, Franz C, Song P, Yamin CK, Keohane C, Denham CR, Bates DW.

JAMA Intern Med. 2013 Dec 9-23;173(22):2039-46. doi: 10.1001/jamainternmed.2013.9763. Review.

PMID:
23999949
35.

Treatment and management of myelofibrosis in the era of JAK inhibitors.

Keohane C, Radia DH, Harrison CN.

Biologics. 2013;7:189-98. doi: 10.2147/BTT.S34942. Epub 2013 Aug 20. Erratum in: Biologics. 2013;7:231.

36.

Return on investment for vendor computerized physician order entry in four community hospitals: the importance of decision support.

Zimlichman E, Keohane C, Franz C, Everett WL, Seger DL, Yoon C, Leung AA, Cadet B, Coffey M, Kaufman NE, Bates DW.

Jt Comm J Qual Patient Saf. 2013 Jul;39(7):312-8.

PMID:
23888641
37.

Lessons learned from implementation of computerized provider order entry in 5 community hospitals: a qualitative study.

Simon SR, Keohane CA, Amato M, Coffey M, Cadet B, Zimlichman E, Bates DW.

BMC Med Inform Decis Mak. 2013 Jun 24;13:67. doi: 10.1186/1472-6947-13-67.

38.

The association of pre-treatment neutrophil to lymphocyte ratio with overall survival in patients with glioblastoma multiforme.

Bambury RM, Teo MY, Power DG, Yusuf A, Murray S, Battley JE, Drake C, O'Dea P, Bermingham N, Keohane C, Grossman SA, Moylan EJ, O'Reilly S.

J Neurooncol. 2013 Aug;114(1):149-54. doi: 10.1007/s11060-013-1164-9. Epub 2013 Jun 19.

PMID:
23780645
39.

The role of JAK1/2 inhibitors in the treatment of chronic myeloproliferative neoplasms.

Keohane C, Mesa R, Harrison C.

Am Soc Clin Oncol Educ Book. 2013:301-5. doi: 10.1200/EdBook_AM.2013.33.301. Review.

40.

Relationship between medication event rates and the Leapfrog computerized physician order entry evaluation tool.

Leung AA, Keohane C, Lipsitz S, Zimlichman E, Amato M, Simon SR, Coffey M, Kaufman N, Cadet B, Schiff G, Seger DL, Bates DW.

J Am Med Inform Assoc. 2013 Jun;20(e1):e85-90. doi: 10.1136/amiajnl-2012-001549. Epub 2013 Apr 18.

41.

Impact of robotic antineoplastic preparation on safety, workflow, and costs.

Seger AC, Churchill WW, Keohane CA, Belisle CD, Wong ST, Sylvester KW, Chesnick MA, Burdick E, Wien MF, Cotugno MC, Bates DW, Rothschild JM.

J Oncol Pract. 2012 Nov;8(6):344-9, 1 p following 349. doi: 10.1200/JOP.2012.000600. Epub 2012 Sep 25.

42.

Focal seizures secondary to cortical dysplasia associated with isolated oral morphea and odontogenic carcinoma.

McNamara PH, Toner M, Kearns G, Keohane C, Daly P, Doherty CP.

Seizure. 2013 Mar;22(2):159-61. doi: 10.1016/j.seizure.2012.11.009. Epub 2012 Dec 30. No abstract available.

43.

Off the hamster wheel? Qualitative evaluation of a payment-linked patient-centered medical home (PCMH) pilot.

Bitton A, Schwartz GR, Stewart EE, Henderson DE, Keohane CA, Bates DW, Schiff GD.

Milbank Q. 2012 Sep;90(3):484-515. doi: 10.1111/j.1468-0009.2012.00672.x.

44.

An exploration of safety climate in nursing homes.

Singer S, Kitch BT, Rao SR, Bonner A, Gaudet J, Bates DW, Field TS, Gurwitz JH, Keohane C, Campbell EG.

J Patient Saf. 2012 Sep;8(3):104-24.

PMID:
22814710
45.

Adverse drug events caused by serious medication administration errors.

Kale A, Keohane CA, Maviglia S, Gandhi TK, Poon EG.

BMJ Qual Saf. 2012 Nov;21(11):933-8. doi: 10.1136/bmjqs-2012-000946. Epub 2012 Jul 12.

46.

'Serpent in the spine': a case of giant spinal ependymoma of cervicothoracic spine.

Arrifin A, Kaliaperumal C, Keohane C, O'Sullivan M.

BMJ Case Rep. 2012 Jun 27;2012:5890. doi: 10.1136/bcr-02-2012-5890.

47.

The costs of adverse drug events in community hospitals.

Hug BL, Keohane C, Seger DL, Yoon C, Bates DW.

Jt Comm J Qual Patient Saf. 2012 Mar;38(3):120-6.

PMID:
22435229
48.

1,3,8-Triazaspiro[4.5]decane-2,4-diones as efficacious pan-inhibitors of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) for the treatment of anemia.

Vachal P, Miao S, Pierce JM, Guiadeen D, Colandrea VJ, Wyvratt MJ, Salowe SP, Sonatore LM, Milligan JA, Hajdu R, Gollapudi A, Keohane CA, Lingham RB, Mandala SM, DeMartino JA, Tong X, Wolff M, Steinhuebel D, Kieczykowski GR, Fleitz FJ, Chapman K, Athanasopoulos J, Adam G, Akyuz CD, Jena DK, Lusen JW, Meng J, Stein BD, Xia L, Sherer EC, Hale JJ.

J Med Chem. 2012 Apr 12;55(7):2945-59. doi: 10.1021/jm201542d. Epub 2012 Feb 27.

PMID:
22364528
49.

Temporal artery biopsy is not required in all cases of suspected giant cell arteritis.

Quinn EM, Kearney DE, Kelly J, Keohane C, Redmond HP.

Ann Vasc Surg. 2012 Jul;26(5):649-54. doi: 10.1016/j.avsg.2011.10.009. Epub 2012 Jan 30.

PMID:
22285348
50.

Impact of vendor computerized physician order entry in community hospitals.

Leung AA, Keohane C, Amato M, Simon SR, Coffey M, Kaufman N, Cadet B, Schiff G, Zimlichman E, Seger DL, Yoon C, Song P, Bates DW.

J Gen Intern Med. 2012 Jul;27(7):801-7. doi: 10.1007/s11606-012-1987-7. Epub 2012 Jan 21.

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