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Items: 19

1.

Effects of Infection by Belonolaimus longicaudatus on Rooting Dynamics among St. Augustinegrass and Bermudagrass Genotypes.

Aryal SK, Crow WT, McSorley R, Giblin-Davis RM, Rowland DL, Poudel B, Kenworthy KE.

J Nematol. 2015 Dec;47(4):322-31.

2.

Zoysiagrass genotype responses to Sphenophorus venatus vestitus (Coleoptera: Curculionidae).

Huang TI, Kostromytska O, Kenworthy KE, Buss EA.

J Econ Entomol. 2014 Aug;107(4):1535-42.

PMID:
25195446
3.

Murine Oatp1a/1b uptake transporters control rosuvastatin systemic exposure without affecting its apparent liver exposure.

Iusuf D, van Esch A, Hobbs M, Taylor M, Kenworthy KE, van de Steeg E, Wagenaar E, Schinkel AH.

Mol Pharmacol. 2013 May;83(5):919-29. doi: 10.1124/mol.112.081927. Epub 2013 Feb 19.

PMID:
23429889
4.

Influence of human OATP1B1, OATP1B3, and OATP1A2 on the pharmacokinetics of methotrexate and paclitaxel in humanized transgenic mice.

van de Steeg E, van Esch A, Wagenaar E, Kenworthy KE, Schinkel AH.

Clin Cancer Res. 2013 Feb 15;19(4):821-32. doi: 10.1158/1078-0432.CCR-12-2080. Epub 2012 Dec 14.

5.

Cyclosporine inhibition of hepatic and intestinal CYP3A4, uptake and efflux transporters: application of PBPK modeling in the assessment of drug-drug interaction potential.

Gertz M, Cartwright CM, Hobbs MJ, Kenworthy KE, Rowland M, Houston JB, Galetin A.

Pharm Res. 2013 Mar;30(3):761-80. doi: 10.1007/s11095-012-0918-y. Epub 2012 Nov 22.

PMID:
23179780
6.

Organic anion-transporting polypeptides 1a/1b control the hepatic uptake of pravastatin in mice.

Iusuf D, Sparidans RW, van Esch A, Hobbs M, Kenworthy KE, van de Steeg E, Wagenaar E, Beijnen JH, Schinkel AH.

Mol Pharm. 2012 Sep 4;9(9):2497-504. doi: 10.1021/mp300108c. Epub 2012 Aug 3.

PMID:
22812517
7.

Use of mechanistic modeling to assess interindividual variability and interspecies differences in active uptake in human and rat hepatocytes.

Ménochet K, Kenworthy KE, Houston JB, Galetin A.

Drug Metab Dispos. 2012 Sep;40(9):1744-56. doi: 10.1124/dmd.112.046193. Epub 2012 Jun 4.

8.

Complete OATP1B1 and OATP1B3 deficiency causes human Rotor syndrome by interrupting conjugated bilirubin reuptake into the liver.

van de Steeg E, Stránecký V, Hartmannová H, Nosková L, Hřebíček M, Wagenaar E, van Esch A, de Waart DR, Oude Elferink RP, Kenworthy KE, Sticová E, al-Edreesi M, Knisely AS, Kmoch S, Jirsa M, Schinkel AH.

J Clin Invest. 2012 Feb;122(2):519-28. doi: 10.1172/JCI59526. Epub 2012 Jan 9.

9.

Simultaneous assessment of uptake and metabolism in rat hepatocytes: a comprehensive mechanistic model.

Ménochet K, Kenworthy KE, Houston JB, Galetin A.

J Pharmacol Exp Ther. 2012 Apr;341(1):2-15. doi: 10.1124/jpet.111.187112. Epub 2011 Dec 21.

10.

Comparison of Water Displacement and WinRHIZO Software for Plant Root Parameter Assessment.

Pang W, Crow WT, Luc JE, McSorley R, Giblin-Davis RM, Kenworthy KE, Kruse JK.

Plant Dis. 2011 Oct;95(10):1308-1310. doi: 10.1094/PDIS-01-11-0026.

PMID:
30731688
11.

Field Responses of Bermudagrass and Seashore paspalum Cultivars to Sting and Spiral Nematodes.

Pang W, Luc JE, Crow WT, Kenworthy KE, Giblin-Davis RM, McSorley R, Kruse JK.

J Nematol. 2011 Sep;43(3-4):201-8.

12.

High impact of Oatp1a/1b transporters on in vivo disposition of the hydrophobic anticancer drug paclitaxel.

van de Steeg E, van Esch A, Wagenaar E, van der Kruijssen CM, van Tellingen O, Kenworthy KE, Schinkel AH.

Clin Cancer Res. 2011 Jan 15;17(2):294-301. doi: 10.1158/1078-0432.CCR-10-1980. Epub 2010 Nov 19.

13.

Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.

van de Steeg E, Wagenaar E, van der Kruijssen CM, Burggraaff JE, de Waart DR, Elferink RP, Kenworthy KE, Schinkel AH.

J Clin Invest. 2010 Aug;120(8):2942-52. doi: 10.1172/JCI42168. Epub 2010 Jul 19.

14.

Organic anion-transporting polypeptide 1B1 mediates transport of Gimatecan and BNP1350 and can be inhibited by several classic ATP-binding cassette (ABC) B1 and/or ABCG2 inhibitors.

Oostendorp RL, van de Steeg E, van der Kruijssen CM, Beijnen JH, Kenworthy KE, Schinkel AH, Schellens JH.

Drug Metab Dispos. 2009 Apr;37(4):917-23. doi: 10.1124/dmd.108.024901. Epub 2009 Jan 12.

PMID:
19139163
15.

Methotrexate pharmacokinetics in transgenic mice with liver-specific expression of human organic anion-transporting polypeptide 1B1 (SLCO1B1).

van de Steeg E, van der Kruijssen CM, Wagenaar E, Burggraaff JE, Mesman E, Kenworthy KE, Schinkel AH.

Drug Metab Dispos. 2009 Feb;37(2):277-81. doi: 10.1124/dmd.108.024315. Epub 2008 Nov 20.

PMID:
19022939
16.

Comparative study of the metabolism of drug substrates by human cytochrome P450 3A4 expressed in bacterial, yeast and human lymphoblastoid cells.

Andrews J, Abd-Ellah MF, Randolph NL, Kenworthy KE, Carlile DJ, Friedberg T, Houston JB.

Xenobiotica. 2002 Nov;32(11):937-47.

PMID:
12487724
17.

Multisite kinetic models for CYP3A4: simultaneous activation and inhibition of diazepam and testosterone metabolism.

Kenworthy KE, Clarke SE, Andrews J, Houston JB.

Drug Metab Dispos. 2001 Dec;29(12):1644-51.

PMID:
11717184
18.

In vitro-in vivo scaling of CYP kinetic data not consistent with the classical Michaelis-Menten model.

Houston JB, Kenworthy KE.

Drug Metab Dispos. 2000 Mar;28(3):246-54. Review.

PMID:
10681367
19.

CYP3A4 drug interactions: correlation of 10 in vitro probe substrates.

Kenworthy KE, Bloomer JC, Clarke SE, Houston JB.

Br J Clin Pharmacol. 1999 Nov;48(5):716-27.

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