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A multifunctional human monoclonal neutralizing antibody that targets a unique conserved epitope on influenza HA.

Bangaru S, Zhang H, Gilchuk IM, Voss TG, Irving RP, Gilchuk P, Matta P, Zhu X, Lang S, Nieusma T, Richt JA, Albrecht RA, Vanderven HA, Bombardi R, Kent SJ, Ward AB, Wilson IA, Crowe JE Jr.

Nat Commun. 2018 Jul 10;9(1):2669. doi: 10.1038/s41467-018-04704-9.


Investigating the JD-R occupational stress model with Australian direct-care workers: A focus group approach.

Heckenberg RA, Kent S, Wright BJ.

Health Soc Care Community. 2018 Jul 10. doi: 10.1111/hsc.12603. [Epub ahead of print]


Exposure to Acute and Chronic Fluoxetine has Differential Effects on Sociability and Activity of Serotonergic Neurons in the Dorsal Raphe Nucleus of Juvenile Male BALB/c Mice.

Payet JM, Burnie E, Sathananthan NJ, Russo AM, Lawther AJ, Kent S, Lowry CA, Hale MW.

Neuroscience. 2018 Jun 27;386:1-15. doi: 10.1016/j.neuroscience.2018.06.022. [Epub ahead of print]


Social approach, anxiety, and altered tryptophan hydroxylase 2 activity in juvenile BALB/c and C57BL/6J mice.

Russo AM, Lawther AJ, Prior BM, Isbel L, Somers WG, Lesku JA, Richdale AL, Dissanayake C, Kent S, Lowry CA, Hale MW.

Behav Brain Res. 2018 Jun 20. pii: S0166-4328(18)30291-2. doi: 10.1016/j.bbr.2018.06.019. [Epub ahead of print]


Neutralizing Antibody-Based Prevention of Cell-Associated HIV-1 Infection.

Parsons MS, Le Grand R, Kent SJ.

Viruses. 2018 Jun 18;10(6). pii: E333. doi: 10.3390/v10060333. Review.


Mucosal-Associated Invariant T Cells Are Depleted and Exhibit Altered Chemokine Receptor Expression and Elevated Granulocyte Macrophage-Colony Stimulating Factor Production During End-Stage Renal Disease.

Juno JA, Waruk JLM, Wragg KM, Mesa C, Lopez C, Bueti J, Kent SJ, Ball TB, Kiazyk SA.

Front Immunol. 2018 May 17;9:1076. doi: 10.3389/fimmu.2018.01076. eCollection 2018.


Anti-influenza Hyperimmune Immunoglobulin Enhances Fc-functional Antibody Immunity during Human Influenza Infection.

Vanderven HA, Wragg K, Ana-Sosa-Batiz F, Kristensen AB, Jegaskanda S, Wheatley AK, Wentworth D, Wines BD, Hogarth PM, Rockman S; INSIGHT FLU005 Pilot Study Writing Group, Kent SJ.

J Infect Dis. 2018 May 31. doi: 10.1093/infdis/jiy328. [Epub ahead of print]


A lipid/DNA adjuvant-inactivated influenza virus vaccine protects rhesus macaques from uncontrolled virus replication after heterosubtypic influenza A virus challenge.

Carroll TD, Jegaskanda S, Matzinger SR, Fritts L, McChesney MB, Kent SJ, Fairman J, Miller CJ.

J Infect Dis. 2018 Apr 26. doi: 10.1093/infdis/jiy238. [Epub ahead of print]


Cystic fibrosis-related diabetes is caused by islet loss and inflammation.

Hart NJ, Aramandla R, Poffenberger G, Fayolle C, Thames AH, Bautista A, Spigelman AF, Babon JAB, DeNicola ME, Dadi PK, Bush WS, Balamurugan AN, Brissova M, Dai C, Prasad N, Bottino R, Jacobson DA, Drumm ML, Kent SC, MacDonald PE, Powers AC.

JCI Insight. 2018 Apr 19;3(8). pii: 98240. doi: 10.1172/jci.insight.98240. [Epub ahead of print]


Healthcare resource use and costs associated with chronic kidney disease in US private insurance patients with multiple myeloma.

Bhowmik D, Song X, Intorcia M, Kent ST, Shi N.

J Oncol Pharm Pract. 2018 Jan 1:1078155218766408. doi: 10.1177/1078155218766408. [Epub ahead of print]


Human plasma proteome association and cytotoxicity of nano-graphene oxide grafted with stealth polyethylene glycol and poly(2-ethyl-2-oxazoline).

Wang M, Gustafsson OJR, Siddiqui G, Javed I, Kelly HG, Blin T, Yin H, Kent SJ, Creek DJ, Kempe K, Ke PC, Davis TP.

Nanoscale. 2018 Jun 14;10(23):10863-10875. doi: 10.1039/c8nr00835c.


Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4+ T Cells in Patients With Type 1 Diabetes.

Marre ML, McGinty JW, Chow IT, DeNicola ME, Beck NW, Kent SC, Powers AC, Bottino R, Harlan DM, Greenbaum CJ, Kwok WW, Piganelli JD, James EA.

Diabetes. 2018 Jul;67(7):1356-1368. doi: 10.2337/db17-1166. Epub 2018 Apr 13.


The effect of antiretroviral intensification with dolutegravir on residual virus replication in HIV-infected individuals: a randomised, placebo-controlled, double-blind trial.

Rasmussen TA, McMahon JH, Chang JJ, Audsley J, Rhodes A, Tennakoon S, Dantanarayana A, Spelman T, Schmidt T, Kent SJ, Morcilla V, Palmer S, Elliott JH, Lewin SR.

Lancet HIV. 2018 May;5(5):e221-e230. doi: 10.1016/S2352-3018(18)30040-7. Epub 2018 Apr 8.


Racemic & quasi-racemic protein crystallography enabled by chemical protein synthesis.

Kent SB.

Curr Opin Chem Biol. 2018 Apr 4;46:1-9. doi: 10.1016/j.cbpa.2018.03.012. [Epub ahead of print] Review.


Neutrophils mediate HIV-specific antibody-dependent phagocytosis and ADCC.

Worley MJ, Fei K, Lopez-Denman AJ, Kelleher AD, Kent SJ, Chung AW.

J Immunol Methods. 2018 Jun;457:41-52. doi: 10.1016/j.jim.2018.03.007. Epub 2018 Mar 29.


The Effects of Coping Interventions on Ability to Perform Under Pressure.

Kent S, Devonport TJ, Lane AM, Nicholls W, Friesen AP.

J Sports Sci Med. 2018 Mar 1;17(1):40-55. eCollection 2018 Mar. Review.


Contribution of NK Cell Education to both Direct and Anti-HIV-1 Antibody-Dependent NK Cell Functions.

Kristensen AB, Kent SJ, Parsons MS.

J Virol. 2018 May 14;92(11). pii: e02146-17. doi: 10.1128/JVI.02146-17. Print 2018 Jun 1.


Corrigendum: Immunoglobulin G1 Allotype Influences Antibody Subclass Distribution in Response to HIV gp140 Vaccination.

Kratochvil S, McKay PF, Chung AW, Kent SJ, Gilmour J, Shattock RJ.

Front Immunol. 2018 Feb 27;9:342. doi: 10.3389/fimmu.2018.00342. eCollection 2018.


Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity.

Koutsakos M, Wheatley AK, Loh L, Clemens EB, Sant S, Nüssing S, Fox A, Chung AW, Laurie KL, Hurt AC, Rockman S, Lappas M, Loudovaris T, Mannering SI, Westall GP, Elliot M, Tangye SG, Wakim LM, Kent SJ, Nguyen THO, Kedzierska K.

Sci Transl Med. 2018 Feb 14;10(428). pii: eaan8405. doi: 10.1126/scitranslmed.aan8405.


Identification of Native and Posttranslationally Modified HLA-B*57:01-Restricted HIV Envelope Derived Epitopes Using Immunoproteomics.

Ramarathinam SH, Gras S, Alcantara S, Yeung AWS, Mifsud NA, Sonza S, Illing PT, Glaros EN, Center RJ, Thomas SR, Kent SJ, Ternette N, Purcell DFJ, Rossjohn J, Purcell AW.

Proteomics. 2018 Jun;18(12):e1700253. doi: 10.1002/pmic.201700253. Epub 2018 Apr 10.


2017 international meeting of the Global Virus Network.

Catton M, Gray G, Griffin D, Hasegawa H, Kent SJ, Mackenzie J, McSweegan E, Mercer N, Wang L.

Antiviral Res. 2018 May;153:60-69. doi: 10.1016/j.antiviral.2018.02.001. Epub 2018 Feb 5. Review.


Is Rheumatoid Arthritis a Cardiovascular Risk Equivalent to Diabetes?

Curtis JR, Yang S, Singh JA, Xie F, Chen L, Yun H, Muntner P, Kent ST, Levitan EB, Safford MM, Saag KG, Zhang J.

Arthritis Care Res (Hoboken). 2018 Feb 6. doi: 10.1002/acr.23535. [Epub ahead of print]


HIV Reactivation after Partial Protection by Neutralizing Antibodies.

Parsons MS, Cromer D, Davenport MP, Kent SJ.

Trends Immunol. 2018 May;39(5):359-366. doi: 10.1016/ Epub 2018 Jan 30. Review.


Immunoglobulin G1 Allotype Influences Antibody Subclass Distribution in Response to HIV gp140 Vaccination.

Kratochvil S, McKay PF, Chung AW, Kent SJ, Gilmore J, Shattock RJ.

Front Immunol. 2017 Dec 20;8:1883. doi: 10.3389/fimmu.2017.01883. eCollection 2017. Erratum in: Front Immunol. 2018 Feb 27;9:342.


Hospital costs in relation to body-mass index in 1·1 million women in England: a prospective cohort study.

Kent S, Green J, Reeves G, Beral V, Gray A, Jebb SA, Cairns BJ, Mihaylova B; Million Women Study collaborators.

Lancet Public Health. 2017 May;2(5):e214-e222. doi: 10.1016/S2468-2667(17)30062-2. Epub 2017 Apr 5.


Anti-HIV-1 antibody-dependent cellular cytotoxicity: is there more to antibodies than neutralization?

Lee WS, Kent SJ.

Curr Opin HIV AIDS. 2018 Mar;13(2):160-166. doi: 10.1097/COH.0000000000000439.


A Role for Fc-Mediated Humoral Immunity in Reducing HIV Transmission Rates between HIV Serodiscordant Heterosexual Couples.

Kent SJ, Chung AW.

EBioMedicine. 2017 Dec;26:2-3. doi: 10.1016/j.ebiom.2017.11.011. Epub 2017 Nov 16. No abstract available.


Antibody-Dependent Cellular Cytotoxicity Responses to Seasonal Influenza Vaccination in Older Adults.

Vanderven HA, Jegaskanda S, Wines BD, Hogarth PM, Carmuglia S, Rockman S, Chung AW, Kent SJ.

J Infect Dis. 2017 Dec 27;217(1):12-23. doi: 10.1093/infdis/jix554.


Induction of vaginal-resident HIV-specific CD8 T cells with mucosal prime-boost immunization.

Tan HX, Wheatley AK, Esterbauer R, Jegaskanda S, Glass JJ, Masopust D, De Rose R, Kent SJ.

Mucosal Immunol. 2018 May;11(3):994-1007. doi: 10.1038/mi.2017.89. Epub 2017 Oct 25.


Antibody-dependent phagocytosis (ADP) responses following trivalent inactivated influenza vaccination of younger and older adults.

Ana-Sosa-Batiz F, Johnston APR, Hogarth PM, Wines BD, Barr I, Wheatley AK, Kent SJ.

Vaccine. 2017 Nov 7;35(47):6451-6458. doi: 10.1016/j.vaccine.2017.09.062. Epub 2017 Oct 10.


Modeling of Antilatency Treatment in HIV: What Is the Optimal Duration of Antiretroviral Therapy-Free HIV Remission?

Cromer D, Pinkevych M, Rasmussen TA, Lewin SR, Kent SJ, Davenport MP.

J Virol. 2017 Nov 30;91(24). pii: e01395-17. doi: 10.1128/JVI.01395-17. Print 2017 Dec 15.


An intensive modular dermatology curriculum for family medicine residents in a resource-limited setting.

McMichael JR, Thompson KB, Kent SC, Stoff BK.

Int J Dermatol. 2018 Jan;57(1):119-120. doi: 10.1111/ijd.13757. Epub 2017 Sep 27. No abstract available.


Exploration of broadly neutralizing antibody fragments produced in bacteria for the control of HIV.

Lloyd SB, Niven KP, Kiefel BR, Montefiori DC, Reynaldi A, Davenport MP, Kent SJ, Winnall WR.

Hum Vaccin Immunother. 2017 Nov 2;13(11):2726-2737. doi: 10.1080/21645515.2017.1368935. Epub 2017 Sep 26.


Templated Polymer Replica Nanoparticles to Facilitate Assessment of Material-Dependent Pharmacokinetics and Biodistribution.

Song D, Cui J, Sun H, Nguyen TH, Alcantara S, De Rose R, Kent SJ, Porter CJH, Caruso F.

ACS Appl Mater Interfaces. 2017 Oct 4;9(39):33683-33694. doi: 10.1021/acsami.7b11579. Epub 2017 Sep 25.


Deciphering the Pathogenesis of Human Type 1 Diabetes (T1D) by Interrogating T Cells from the "Scene of the Crime".

Kent SC, Mannering SI, Michels AW, Babon JAB.

Curr Diab Rep. 2017 Sep 2;17(10):95. doi: 10.1007/s11892-017-0915-y. Review.


Changes in pediatric tracheostomy tubes exposed to home dishwashing.

Smolar DE, Ho B, Kent SM, Hughes CA, Mettenburg D, Rueggeberg FA, Groves MW.

Int J Pediatr Otorhinolaryngol. 2017 Sep;100:96-102. doi: 10.1016/j.ijporl.2017.06.020. Epub 2017 Jun 20.


Partial efficacy of a broadly neutralizing antibody against cell-associated SHIV infection.

Parsons MS, Lloyd SB, Lee WS, Kristensen AB, Amarasena T, Center RJ, Keele BF, Lifson JD, LaBranche CC, Montefiori D, Wines BD, Hogarth PM, Swiderek KM, Venturi V, Davenport MP, Kent SJ.

Sci Transl Med. 2017 Aug 9;9(402). pii: eaaf1483. doi: 10.1126/scitranslmed.aaf1483.


A policy model of cardiovascular disease in moderate-to-advanced chronic kidney disease.

Schlackow I, Kent S, Herrington W, Emberson J, Haynes R, Reith C, Wanner C, Fellström B, Gray A, Landray MJ, Baigent C, Mihaylova B; SHARP Collaborative Group.

Heart. 2017 Dec;103(23):1880-1890. doi: 10.1136/heartjnl-2016-310970. Epub 2017 Aug 5.


Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes.

Babon JAB, DeNicola ME, Blodgett DM, Crèvecoeur I, Buttrick TS, Maehr R, Bottino R, Naji A, Kaddis J, Elyaman W, James EA, Haliyur R, Brissova M, Overbergh L, Mathieu C, Delong T, Haskins K, Pugliese A, Campbell-Thompson M, Mathews C, Atkinson MA, Powers AC, Harlan DM, Kent SC.

Nat Med. 2017 Aug 4;23(8):1004. doi: 10.1038/nm0817-1004a. No abstract available.


PCSK9 Loss-of-Function Variants, Low-Density Lipoprotein Cholesterol, and Risk of Coronary Heart Disease and Stroke: Data From 9 Studies of Blacks and Whites.

Kent ST, Rosenson RS, Avery CL, Chen YI, Correa A, Cummings SR, Cupples LA, Cushman M, Evans DS, Gudnason V, Harris TB, Howard G, Irvin MR, Judd SE, Jukema JW, Lange L, Levitan EB, Li X, Liu Y, Post WS, Postmus I, Psaty BM, Rotter JI, Safford MM, Sitlani CM, Smith AV, Stewart JD, Trompet S, Sun F, Vasan RS, Woolley JM, Whitsel EA, Wiggins KL, Wilson JG, Muntner P.

Circ Cardiovasc Genet. 2017 Aug;10(4):e001632. doi: 10.1161/CIRCGENETICS.116.001632.


Barriers to conducting ambulatory and home blood pressure monitoring during hypertension screening in the United States.

Kronish IM, Kent S, Moise N, Shimbo D, Safford MM, Kynerd RE, O'Beirne R, Sullivan A, Muntner P.

J Am Soc Hypertens. 2017 Sep;11(9):573-580. doi: 10.1016/j.jash.2017.06.012. Epub 2017 Jul 6.


HIV-1 Env- and Vpu-Specific Antibody-Dependent Cellular Cytotoxicity Responses Associated with Elite Control of HIV.

Madhavi V, Wines BD, Amin J, Emery S; ENCORE1 Study Group, Lopez E, Kelleher A; Sydney LTNP Study Group, Center RJ, Hogarth PM, Chung AW, Kent SJ, Stratov I.

J Virol. 2017 Aug 24;91(18). pii: e00700-17. doi: 10.1128/JVI.00700-17. Print 2017 Sep 15.


Chemical protein synthesis: Inventing synthetic methods to decipher how proteins work.

Kent S.

Bioorg Med Chem. 2017 Sep 15;25(18):4926-4937. doi: 10.1016/j.bmc.2017.06.020. Epub 2017 Jun 15. Review.


Fc functional antibodies in humans with severe H7N9 and seasonal influenza.

Vanderven HA, Liu L, Ana-Sosa-Batiz F, Nguyen TH, Wan Y, Wines B, Hogarth PM, Tilmanis D, Reynaldi A, Parsons MS, Hurt AC, Davenport MP, Kotsimbos T, Cheng AC, Kedzierska K, Zhang X, Xu J, Kent SJ.

JCI Insight. 2017 Jul 6;2(13). pii: 92750. doi: 10.1172/jci.insight.92750. [Epub ahead of print]


Approximately One In Three US Adults Completes Any Type Of Advance Directive For End-Of-Life Care.

Yadav KN, Gabler NB, Cooney E, Kent S, Kim J, Herbst N, Mante A, Halpern SD, Courtright KR.

Health Aff (Millwood). 2017 Jul 1;36(7):1244-1251. doi: 10.1377/hlthaff.2017.0175. Review.


Race and sex differences in ambulatory blood pressure measures among HIV+ adults.

Kent ST, Schwartz JE, Shimbo D, Overton ET, Burkholder GA, Oparil S, Mugavero MJ, Muntner P.

J Am Soc Hypertens. 2017 Jul;11(7):420-427.e3. doi: 10.1016/j.jash.2017.05.002. Epub 2017 May 25.


Six-Month Morbidity and Mortality among Intensive Care Unit Patients Receiving Life-Sustaining Therapy. A Prospective Cohort Study.

Detsky ME, Harhay MO, Bayard DF, Delman AM, Buehler AE, Kent SA, Ciuffetelli IV, Cooney E, Gabler NB, Ratcliffe SJ, Mikkelsen ME, Halpern SD.

Ann Am Thorac Soc. 2017 Oct;14(10):1562-1570. doi: 10.1513/AnnalsATS.201611-875OC.


Dimeric Fcγ Receptor Enzyme-Linked Immunosorbent Assay To Study HIV-Specific Antibodies: A New Look into Breadth of Fcγ Receptor Antibodies Induced by the RV144 Vaccine Trial.

McLean MR, Madhavi V, Wines BD, Hogarth PM, Chung AW, Kent SJ.

J Immunol. 2017 Jul 15;199(2):816-826. doi: 10.4049/jimmunol.1602161. Epub 2017 Jun 14.


A Phase 1 Human Immunodeficiency Virus Vaccine Trial for Cross-Profiling the Kinetics of Serum and Mucosal Antibody Responses to CN54gp140 Modulated by Two Homologous Prime-Boost Vaccine Regimens.

Kratochvil S, McKay PF, Kopycinski JT, Bishop C, Hayes PJ, Muir L, Pinder CL, Cizmeci D, King D, Aldon Y, Wines BD, Hogarth PM, Chung AW, Kent SJ, Held K, Geldmacher C, Dally L, Santos NS, Cole T, Gilmour J, Fidler S, Shattock RJ.

Front Immunol. 2017 May 24;8:595. doi: 10.3389/fimmu.2017.00595. eCollection 2017.


Reinvestigation of the biological activity of d-allo-ShK protein.

Dang B, Chhabra S, Pennington MW, Norton RS, Kent SBH.

J Biol Chem. 2017 Jul 28;292(30):12599-12605. doi: 10.1074/jbc.M117.793943. Epub 2017 Jun 8.


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