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Items: 47

1.

Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake.

Ko SY, Lee W, Kenny HA, Dang LH, Ellis LM, Jonasch E, Lengyel E, Naora H.

Commun Biol. 2019 Oct 18;2:386. doi: 10.1038/s42003-019-0609-x. eCollection 2019.

2.

Quantitative high-throughput screening using an organotypic model identifies compounds that inhibit ovarian cancer metastasis.

Kenny HA, Lal-Nag M, Shen M, Kara B, Nahotko DA, Wroblewski K, Fazal S, Chen S, Chiang CY, Chen YJ, Brimacombe KR, Marugan J, Ferrer M, Lengyel E.

Mol Cancer Ther. 2019 Sep 27. pii: molcanther.0052.2019. doi: 10.1158/1535-7163.MCT-19-0052. [Epub ahead of print]

PMID:
31562255
3.

Phenotypic Responses to a Lifestyle Intervention Do Not Account for Inter-Individual Variability in Glucose Tolerance for Individuals at High Risk of Type 2 Diabetes.

O'Donoghue G, Kennedy A, Andersen GS, Carr B, Cleary S, Durkan E, Davis H, Færch K, Fitzpatrick P, Kenny H, McCaffrey N, Monedero J, Murphy E, Noone J, Suvitaival T, Thybo T, Wheeler M, Vistisen D, Nolan JJ, O'Gorman DJ.

Front Physiol. 2019 Mar 26;10:317. doi: 10.3389/fphys.2019.00317. eCollection 2019.

4.

Safety and Effectiveness of Cochlear Implantation of Young Children, Including Those With Complicating Conditions.

Hoff S, Ryan M, Thomas D, Tournis E, Kenny H, Hajduk J, Young NM.

Otol Neurotol. 2019 Apr;40(4):454-463. doi: 10.1097/MAO.0000000000002156.

5.

Inhibition of fascin in cancer and stromal cells blocks ovarian cancer metastasis.

McGuire S, Kara B, Hart PC, Montag A, Wroblewski K, Fazal S, Huang XY, Lengyel E, Kenny HA.

Gynecol Oncol. 2019 May;153(2):405-415. doi: 10.1016/j.ygyno.2019.01.020. Epub 2019 Feb 20.

PMID:
30797592
6.

Heart Failure in Type 2 Diabetes Mellitus.

Kenny HC, Abel ED.

Circ Res. 2019 Jan 4;124(1):121-141. doi: 10.1161/CIRCRESAHA.118.311371. Review.

PMID:
30605420
7.

Neutrophils facilitate ovarian cancer premetastatic niche formation in the omentum.

Lee W, Ko SY, Mohamed MS, Kenny HA, Lengyel E, Naora H.

J Exp Med. 2019 Jan 7;216(1):176-194. doi: 10.1084/jem.20181170. Epub 2018 Dec 19.

8.

Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis.

Curtis M, Kenny HA, Ashcroft B, Mukherjee A, Johnson A, Zhang Y, Helou Y, Batlle R, Liu X, Gutierrez N, Gao X, Yamada SD, Lastra R, Montag A, Ahsan N, Locasale JW, Salomon AR, Nebreda AR, Lengyel E.

Cell Metab. 2019 Jan 8;29(1):141-155.e9. doi: 10.1016/j.cmet.2018.08.007. Epub 2018 Aug 30.

PMID:
30174305
9.

Organotypic 3D Models of the Ovarian Cancer Tumor Microenvironment.

Watters KM, Bajwa P, Kenny HA.

Cancers (Basel). 2018 Aug 9;10(8). pii: E265. doi: 10.3390/cancers10080265. Review.

10.

Non-lethal isolation of the fungal pathogen Batrachochytrium dendrobatidis (Bd) from amphibians.

Cook KJ, Voyles J, Kenny HV, Pope KL, Piovia-Scott J.

Dis Aquat Organ. 2018 Jul 4;129(2):159-164. doi: 10.3354/dao03238.

PMID:
29972376
11.

ALTERATIONS IN THYROID HORMONE LEVELS FOLLOWING GROWTH HORMONE REPLACEMENT EXERT COMPLEX BIOLOGICAL EFFECTS.

Glynn N, Kenny H, Salim T, Halsall DJ, Smith D, Tun TK, McDermott JH, Tormey W, Thompson CJ, McAdam B, O' Gorman D, Agha A.

Endocr Pract. 2018 Apr;24(4):342-350. doi: 10.4158/EP-2017-0223.

PMID:
29658834
12.

Adipocyte-induced CD36 expression drives ovarian cancer progression and metastasis.

Ladanyi A, Mukherjee A, Kenny HA, Johnson A, Mitra AK, Sundaresan S, Nieman KM, Pascual G, Benitah SA, Montag A, Yamada SD, Abumrad NA, Lengyel E.

Oncogene. 2018 Apr;37(17):2285-2301. doi: 10.1038/s41388-017-0093-z. Epub 2018 Feb 5.

13.

Marine subsidies change short-term foraging activity and habitat utilization of terrestrial lizards.

Kenny HV, Wright AN, Piovia-Scott J, Yang LH, Spiller DA, Schoener TW.

Ecol Evol. 2017 Nov 7;7(24):10701-10709. doi: 10.1002/ece3.3560. eCollection 2017 Dec.

14.

Mitochondrial Reactive Oxygen Species in Lipotoxic Hearts Induce Post-Translational Modifications of AKAP121, DRP1, and OPA1 That Promote Mitochondrial Fission.

Tsushima K, Bugger H, Wende AR, Soto J, Jenson GA, Tor AR, McGlauflin R, Kenny HC, Zhang Y, Souvenir R, Hu XX, Sloan CL, Pereira RO, Lira VA, Spitzer KW, Sharp TL, Shoghi KI, Sparagna GC, Rog-Zielinska EA, Kohl P, Khalimonchuk O, Schaffer JE, Abel ED.

Circ Res. 2018 Jan 5;122(1):58-73. doi: 10.1161/CIRCRESAHA.117.311307. Epub 2017 Nov 1.

15.

Bed rest and resistive vibration exercise unveil novel links between skeletal muscle mitochondrial function and insulin resistance.

Kenny HC, Rudwill F, Breen L, Salanova M, Blottner D, Heise T, Heer M, Blanc S, O'Gorman DJ.

Diabetologia. 2017 Aug;60(8):1491-1501. doi: 10.1007/s00125-017-4298-z. Epub 2017 May 12.

PMID:
28500394
16.

A High-Throughput Screening Model of the Tumor Microenvironment for Ovarian Cancer Cell Growth.

Lal-Nag M, McGee L, Guha R, Lengyel E, Kenny HA, Ferrer M.

SLAS Discov. 2017 Jun;22(5):494-506. doi: 10.1177/2472555216687082. Epub 2017 Jan 31.

17.

Unsaturated Fatty Acids Maintain Cancer Cell Stemness.

Mukherjee A, Kenny HA, Lengyel E.

Cell Stem Cell. 2017 Mar 2;20(3):291-292. doi: 10.1016/j.stem.2017.02.008.

18.

Greater Species Richness of Bacterial Skin Symbionts Better Suppresses the Amphibian Fungal Pathogen Batrachochytrium Dendrobatidis.

Piovia-Scott J, Rejmanek D, Woodhams DC, Worth SJ, Kenny H, McKenzie V, Lawler SP, Foley JE.

Microb Ecol. 2017 Jul;74(1):217-226. doi: 10.1007/s00248-016-0916-4. Epub 2017 Jan 7.

PMID:
28064360
19.

The effect of growth hormone replacement on the thyroid axis in patients with hypopituitarism: in vivo and ex vivo studies.

Glynn N, Kenny H, Quisenberry L, Halsall DJ, Cook P, Kyaw Tun T, McDermott JH, Smith D, Thompson CJ, O'Gorman DJ, Boelen A, Lado-Abeal J, Agha A.

Clin Endocrinol (Oxf). 2017 May;86(5):747-754. doi: 10.1111/cen.13272. Epub 2016 Dec 19.

PMID:
27809356
20.

Reversal of Chemoresistance in Ovarian Cancer by Co-Delivery of a P-Glycoprotein Inhibitor and Paclitaxel in a Liposomal Platform.

Zhang Y, Sriraman SK, Kenny HA, Luther E, Torchilin V, Lengyel E.

Mol Cancer Ther. 2016 Oct;15(10):2282-2293. Epub 2016 Jul 27.

21.

Erratum: Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.

Kenny HA, Lal-Nag M, White EA, Shen M, Chiang CY, Mitra AK, Zhang Y, Curtis M, Schryver EM, Bettis S, Jadhav A, Boxer MB, Li Z, Ferrer M, Lengyel E.

Nat Commun. 2016 Feb 3;7:10649. doi: 10.1038/ncomms10649. No abstract available.

22.

Modeling the Early Steps of Ovarian Cancer Dissemination in an Organotypic Culture of the Human Peritoneal Cavity.

Peters PN, Schryver EM, Lengyel E, Kenny H.

J Vis Exp. 2015 Dec 31;(106):e53541. doi: 10.3791/53541.

23.

Molecular pathways: trafficking of metabolic resources in the tumor microenvironment.

Romero IL, Mukherjee A, Kenny HA, Litchfield LM, Lengyel E.

Clin Cancer Res. 2015 Feb 15;21(4):680-6. doi: 10.1158/1078-0432.CCR-14-2198. Review.

24.

Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.

Kenny HA, Lal-Nag M, White EA, Shen M, Chiang CY, Mitra AK, Zhang Y, Curtis M, Schryver EM, Bettis S, Jadhav A, Boxer MB, Li Z, Ferrer M, Lengyel E.

Nat Commun. 2015 Feb 5;6:6220. doi: 10.1038/ncomms7220. Erratum in: Nat Commun. 2016;7:10649.

25.

Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion.

Kenny HA, Chiang CY, White EA, Schryver EM, Habis M, Romero IL, Ladanyi A, Penicka CV, George J, Matlin K, Montag A, Wroblewski K, Yamada SD, Mazar AP, Bowtell D, Lengyel E.

J Clin Invest. 2014 Oct;124(10):4614-28. doi: 10.1172/JCI74778. Epub 2014 Sep 9.

26.

Three-dimensional modeling of ovarian cancer.

White EA, Kenny HA, Lengyel E.

Adv Drug Deliv Rev. 2014 Dec 15;79-80:184-92. doi: 10.1016/j.addr.2014.07.003. Epub 2014 Jul 14. Review.

27.

Urokinase plasminogen activator system-targeted delivery of nanobins as a novel ovarian cancer therapy.

Zhang Y, Kenny HA, Swindell EP, Mitra AK, Hankins PL, Ahn RW, Gwin K, Mazar AP, O'Halloran TV, Lengyel E.

Mol Cancer Ther. 2013 Dec;12(12):2628-39. doi: 10.1158/1535-7163.MCT-13-0204. Epub 2013 Sep 23.

28.

Epithelial ovarian cancer experimental models.

Lengyel E, Burdette JE, Kenny HA, Matei D, Pilrose J, Haluska P, Nephew KP, Hales DB, Stack MS.

Oncogene. 2014 Jul 10;33(28):3619-33. doi: 10.1038/onc.2013.321. Epub 2013 Aug 12. Review.

29.

The effect of exercise on osteoprotegerin and TNF-related apoptosis-inducing ligand in obese patients.

Davenport C, Kenny H, Ashley DT, O'Sullivan EP, Smith D, O'Gorman DJ.

Eur J Clin Invest. 2012 Nov;42(11):1173-9. doi: 10.1111/j.1365-2362.2012.02703.x. Epub 2012 Jul 17.

PMID:
22803952
30.

Adipocytes promote ovarian cancer metastasis and provide energy for rapid tumor growth.

Nieman KM, Kenny HA, Penicka CV, Ladanyi A, Buell-Gutbrod R, Zillhardt MR, Romero IL, Carey MS, Mills GB, Hotamisligil GS, Yamada SD, Peter ME, Gwin K, Lengyel E.

Nat Med. 2011 Oct 30;17(11):1498-503. doi: 10.1038/nm.2492.

31.

The first line of intra-abdominal metastatic attack: breaching the mesothelial cell layer.

Kenny HA, Nieman KM, Mitra AK, Lengyel E.

Cancer Discov. 2011 Jul;1(2):100-2. doi: 10.1158/2159-8290.CD-11-0117.

32.

Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis.

Kenny HA, Leonhardt P, Ladanyi A, Yamada SD, Montag A, Im HK, Jagadeeswaran S, Shaw DE, Mazar AP, Lengyel E.

Clin Cancer Res. 2011 Feb 1;17(3):459-71. doi: 10.1158/1078-0432.CCR-10-2258. Epub 2010 Dec 13.

33.

{beta}3-integrin expression on tumor cells inhibits tumor progression, reduces metastasis, and is associated with a favorable prognosis in patients with ovarian cancer.

Kaur S, Kenny HA, Jagadeeswaran S, Zillhardt MR, Montag AG, Kistner E, Yamada SD, Mitra AK, Lengyel E.

Am J Pathol. 2009 Nov;175(5):2184-96. doi: 10.2353/ajpath.2009.090028. Epub 2009 Oct 1.

34.

Organotypic models of metastasis: A three-dimensional culture mimicking the human peritoneum and omentum for the study of the early steps of ovarian cancer metastasis.

Kenny HA, Dogan S, Zillhardt M, K Mitra A, Yamada SD, Krausz T, Lengyel E.

Cancer Treat Res. 2009;149:335-51. doi: 10.1007/978-0-387-98094-2_16. Review. No abstract available.

35.

MMP-2 functions as an early response protein in ovarian cancer metastasis.

Kenny HA, Lengyel E.

Cell Cycle. 2009 Mar 1;8(5):683-8. Epub 2009 Mar 25.

36.

Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target.

Sawada K, Mitra AK, Radjabi AR, Bhaskar V, Kistner EO, Tretiakova M, Jagadeeswaran S, Montag A, Becker A, Kenny HA, Peter ME, Ramakrishnan V, Yamada SD, Lengyel E.

Cancer Res. 2008 Apr 1;68(7):2329-39. doi: 10.1158/0008-5472.CAN-07-5167.

37.

The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.

Kenny HA, Kaur S, Coussens LM, Lengyel E.

J Clin Invest. 2008 Apr;118(4):1367-79. doi: 10.1172/JCI33775.

38.

Thrombin induces tumor invasion through the induction and association of matrix metalloproteinase-9 and beta1-integrin on the cell surface.

Radjabi AR, Sawada K, Jagadeeswaran S, Eichbichler A, Kenny HA, Montag A, Bruno K, Lengyel E.

J Biol Chem. 2008 Feb 1;283(5):2822-34. Epub 2007 Nov 29.

40.

c-Met overexpression is a prognostic factor in ovarian cancer and an effective target for inhibition of peritoneal dissemination and invasion.

Sawada K, Radjabi AR, Shinomiya N, Kistner E, Kenny H, Becker AR, Turkyilmaz MA, Salgia R, Yamada SD, Vande Woude GF, Tretiakova MS, Lengyel E.

Cancer Res. 2007 Feb 15;67(4):1670-9.

41.

Follicle size class contributes to distinct secretion patterns of inhibin isoforms during the rat estrous cycle.

Kenny HA, Woodruff TK.

Endocrinology. 2006 Jan;147(1):51-60. Epub 2005 Sep 29.

PMID:
16195413
42.

Ovarian follicle development requires Smad3.

Tomic D, Miller KP, Kenny HA, Woodruff TK, Hoyer P, Flaws JA.

Mol Endocrinol. 2004 Sep;18(9):2224-40. Epub 2004 Jun 10.

PMID:
15192076
43.
44.

Photoperiod-dependent regulation of inhibin in Siberian hamsters: I. Ovarian inhibin production and secretion.

Kenny HA, Bernard DJ, Horton TH, Woodruff TK.

J Endocrinol. 2002 Jul;174(1):71-83.

PMID:
12098665
45.
46.

The hearing-aid battery: a hazard to elderly patients.

Strachan DR, Kenny H, Hope GA.

Age Ageing. 1994 Sep;23(5):425-6.

PMID:
7825492
47.

Silver nitrate treatment of burns. Technique and controlling principles.

Wood M, Kenny HA, Price WR.

Am J Nurs. 1966 Mar;66(3):518-21. No abstract available.

PMID:
5175289

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