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Items: 1 to 50 of 70

1.

Mitochondrial oxidation of the carbohydrate fuel is required for neural precursor/stem cell function and postnatal cerebellar development.

Zheng H, Yu WM, Shen J, Kang S, Hambardzumyan D, Li JY, Shen Y, Kenney AM, Chen J, Qu CK.

Sci Adv. 2018 Oct 10;4(10):eaat2681. doi: 10.1126/sciadv.aat2681. eCollection 2018 Oct.

PMID:
30338292
2.

p53 Function is Compromised by Inhibitor 2 of Phosphatase 2A in Sonic Hedgehog Medulloblastoma.

Wei Y, Maximov V, Morrissy SA, Taylor MD, Pallas DC, Kenney AM.

Mol Cancer Res. 2018 Sep 17. doi: 10.1158/1541-7786.MCR-18-0485. [Epub ahead of print]

PMID:
30224541
3.

Genetic Mapping Reveals an Anthocyanin Biosynthesis Pathway Gene Potentially Influencing Evolutionary Divergence between Two Subspecies of Scarlet Gilia (Ipomopsis aggregata).

Campitelli BE, Kenney AM, Hopkins R, Soule J, Lovell JT, Juenger TE.

Mol Biol Evol. 2018 Apr 1;35(4):807-822. doi: 10.1093/molbev/msx318.

PMID:
29253197
4.

miR miR on the wall, who's the most malignant medulloblastoma miR of them all?

Wang X, Holgado BL, Ramaswamy V, Mack S, Zayne K, Remke M, Wu X, Garzia L, Daniels C, Kenney AM, Taylor MD.

Neuro Oncol. 2018 Feb 19;20(3):313-323. doi: 10.1093/neuonc/nox106.

PMID:
28575493
5.

WIP1 modulates responsiveness to Sonic Hedgehog signaling in neuronal precursor cells and medulloblastoma.

Wen J, Lee J, Malhotra A, Nahta R, Arnold AR, Buss MC, Brown BD, Maier C, Kenney AM, Remke M, Ramaswamy V, Taylor MD, Castellino RC.

Oncogene. 2016 Oct 20;35(42):5552-5564. doi: 10.1038/onc.2016.96. Epub 2016 Apr 18.

6.

Adaptive differentiation in floral traits in the presence of high gene flow in scarlet gilia (Ipomopsis aggregata).

Milano ER, Kenney AM, Juenger TE.

Mol Ecol. 2016 Dec;25(23):5862-5875. doi: 10.1111/mec.13752. Epub 2016 Aug 8.

PMID:
27392816
7.

Reproductive isolation and introgression between sympatric Mimulus species.

Kenney AM, Sweigart AL.

Mol Ecol. 2016 Jun;25(11):2499-517. doi: 10.1111/mec.13630. Epub 2016 May 11.

PMID:
27038381
8.

Genetic loci with parent-of-origin effects cause hybrid seed lethality in crosses between Mimulus species.

Garner AG, Kenney AM, Fishman L, Sweigart AL.

New Phytol. 2016 Jul;211(1):319-31. doi: 10.1111/nph.13897. Epub 2016 Feb 29.

9.

YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells.

Dey A, Robitaille M, Remke M, Maier C, Malhotra A, Gregorieff A, Wrana JL, Taylor MD, Angers S, Kenney AM.

Oncogene. 2016 Aug 11;35(32):4256-68. doi: 10.1038/onc.2015.491. Epub 2016 Jan 4.

10.

Sonic Hedgehog Signaling Drives Mitochondrial Fragmentation by Suppressing Mitofusins in Cerebellar Granule Neuron Precursors and Medulloblastoma.

Malhotra A, Dey A, Prasad N, Kenney AM.

Mol Cancer Res. 2016 Jan;14(1):114-24. doi: 10.1158/1541-7786.MCR-15-0278. Epub 2015 Oct 7.

11.

Direct and indirect selection on flowering time, water-use efficiency (WUE, δ (13)C), and WUE plasticity to drought in Arabidopsis thaliana.

Kenney AM, McKay JK, Richards JH, Juenger TE.

Ecol Evol. 2014 Dec;4(23):4505-21. doi: 10.1002/ece3.1270. Epub 2014 Nov 19.

12.

Speciation and introgression between Mimulus nasutus and Mimulus guttatus.

Brandvain Y, Kenney AM, Flagel L, Coop G, Sweigart AL.

PLoS Genet. 2014 Jun 26;10(6):e1004410. doi: 10.1371/journal.pgen.1004410. eCollection 2014 Jun.

13.

Evolutionary genetics of plant adaptation: insights from new model systems.

Zuellig MP, Kenney AM, Sweigart AL.

Curr Opin Plant Biol. 2014 Apr;18:44-50. doi: 10.1016/j.pbi.2014.01.001. Epub 2014 Feb 19. Review.

PMID:
24561539
14.

Major quantitative trait loci control divergence in critical photoperiod for flowering between selfing and outcrossing species of monkeyflower (Mimulus).

Fishman L, Sweigart AL, Kenney AM, Campbell S.

New Phytol. 2014 Mar;201(4):1498-507. doi: 10.1111/nph.12618. Epub 2013 Dec 4.

15.

Subgroup-specific structural variation across 1,000 medulloblastoma genomes.

Northcott PA, Shih DJ, Peacock J, Garzia L, Morrissy AS, Zichner T, Stütz AM, Korshunov A, Reimand J, Schumacher SE, Beroukhim R, Ellison DW, Marshall CR, Lionel AC, Mack S, Dubuc A, Yao Y, Ramaswamy V, Luu B, Rolider A, Cavalli FM, Wang X, Remke M, Wu X, Chiu RY, Chu A, Chuah E, Corbett RD, Hoad GR, Jackman SD, Li Y, Lo A, Mungall KL, Nip KM, Qian JQ, Raymond AG, Thiessen NT, Varhol RJ, Birol I, Moore RA, Mungall AJ, Holt R, Kawauchi D, Roussel MF, Kool M, Jones DT, Witt H, Fernandez-L A, Kenney AM, Wechsler-Reya RJ, Dirks P, Aviv T, Grajkowska WA, Perek-Polnik M, Haberler CC, Delattre O, Reynaud SS, Doz FF, Pernet-Fattet SS, Cho BK, Kim SK, Wang KC, Scheurlen W, Eberhart CG, Fèvre-Montange M, Jouvet A, Pollack IF, Fan X, Muraszko KM, Gillespie GY, Di Rocco C, Massimi L, Michiels EM, Kloosterhof NK, French PJ, Kros JM, Olson JM, Ellenbogen RG, Zitterbart K, Kren L, Thompson RC, Cooper MK, Lach B, McLendon RE, Bigner DD, Fontebasso A, Albrecht S, Jabado N, Lindsey JC, Bailey S, Gupta N, Weiss WA, Bognár L, Klekner A, Van Meter TE, Kumabe T, Tominaga T, Elbabaa SK, Leonard JR, Rubin JB, Liau LM, Van Meir EG, Fouladi M, Nakamura H, Cinalli G, Garami M, Hauser P, Saad AG, Iolascon A, Jung S, Carlotti CG, Vibhakar R, Ra YS, Robinson S, Zollo M, Faria CC, Chan JA, Levy ML, Sorensen PH, Meyerson M, Pomeroy SL, Cho YJ, Bader GD, Tabori U, Hawkins CE, Bouffet E, Scherer SW, Rutka JT, Malkin D, Clifford SC, Jones SJ, Korbel JO, Pfister SM, Marra MA, Taylor MD.

Nature. 2012 Aug 2;488(7409):49-56. doi: 10.1038/nature11327.

16.

Hedgehog-mediated regulation of PPARγ controls metabolic patterns in neural precursors and shh-driven medulloblastoma.

Bhatia B, Potts CR, Guldal C, Choi S, Korshunov A, Pfister S, Kenney AM, Nahlé ZA.

Acta Neuropathol. 2012 Apr;123(4):587-600. doi: 10.1007/s00401-012-0968-6. Epub 2012 Mar 11.

17.

An essential role for p38 MAPK in cerebellar granule neuron precursor proliferation.

Guldal CG, Ahmad A, Korshunov A, Squatrito M, Awan A, Mainwaring LA, Bhatia B, Parathath SR, Nahle Z, Pfister S, Kenney AM.

Acta Neuropathol. 2012 Apr;123(4):573-86. doi: 10.1007/s00401-012-0946-z.

18.

Reciprocal actions of ATF5 and Shh in proliferation of cerebellar granule neuron progenitor cells.

Lee HY, Angelastro JM, Kenney AM, Mason CA, Greene LA.

Dev Neurobiol. 2012 Jun;72(6):789-804. doi: 10.1002/dneu.20979.

19.

Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation.

Fernandez-L A, Squatrito M, Northcott P, Awan A, Holland EC, Taylor MD, Nahlé Z, Kenney AM.

Oncogene. 2012 Apr 12;31(15):1923-37. doi: 10.1038/onc.2011.379. Epub 2011 Aug 29.

20.

Divergent functions for eIF4E and S6 kinase by sonic hedgehog mitogenic signaling in the developing cerebellum.

Mainwaring LA, Kenney AM.

Oncogene. 2011 Apr 14;30(15):1784-97. doi: 10.1038/onc.2010.564. Epub 2011 Feb 21.

21.

Myc on my mind: a transcription factor family's essential role in brain development.

Mainwaring LA, Bhatia B, Kenney AM.

Oncotarget. 2010 Jun;1(2):86-8. No abstract available.

22.

Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups.

Ellison DW, Dalton J, Kocak M, Nicholson SL, Fraga C, Neale G, Kenney AM, Brat DJ, Perry A, Yong WH, Taylor RE, Bailey S, Clifford SC, Gilbertson RJ.

Acta Neuropathol. 2011 Mar;121(3):381-96. doi: 10.1007/s00401-011-0800-8. Epub 2011 Jan 26.

23.

p27(Kip1), a double-edged sword in Shh-mediated medulloblastoma: Tumor accelerator and suppressor.

Bhatia B, Malik A, Fernandez-L A, Kenney AM.

Cell Cycle. 2010 Nov 1;9(21):4307-14. Epub 2010 Nov 27.

24.

β-Arrestin-1 links mitogenic sonic hedgehog signaling to the cell cycle exit machinery in neural precursors.

Parathath SR, Mainwaring LA, Fernandez-L A, Guldal CG, Nahlé Z, Kenney AM.

Cell Cycle. 2010 Oct 1;9(19):4013-24. Epub 2010 Oct 11.

25.

Calculating a cure for cancer: managing medulloblastoma MATH1-ematically.

Dubuc AM, Northcott PA, Kenney AM, Taylor MD.

Expert Rev Neurother. 2010 Oct;10(10):1489-92. doi: 10.1586/ern.10.126. No abstract available.

PMID:
20925463
26.

Mitogenic Sonic hedgehog signaling drives E2F1-dependent lipogenesis in progenitor cells and medulloblastoma.

Bhatia B, Hsieh M, Kenney AM, Nahlé Z.

Oncogene. 2011 Jan 27;30(4):410-22. doi: 10.1038/onc.2010.454. Epub 2010 Oct 4. Erratum in: Oncogene. 2011 Jan 27;30(4):504.

27.

The Hippo in the room: a new look at a key pathway in cell growth and transformation.

Fernandez-L A, Kenney AM.

Cell Cycle. 2010 Jun 15;9(12):2292-9. doi: 10.4161/cc.9.12.11919. Epub 2010 Jun 15.

PMID:
20581446
28.

Double trouble: when sonic hedgehog signaling meets TSC inactivation.

Bhatia B, Nahlé Z, Kenney AM.

Cell Cycle. 2010 Feb 1;9(3):456-9. Epub 2010 Feb 6.

PMID:
20081363
29.

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation.

Fernandez-L A, Northcott PA, Dalton J, Fraga C, Ellison D, Angers S, Taylor MD, Kenney AM.

Genes Dev. 2009 Dec 1;23(23):2729-41. doi: 10.1101/gad.1824509.

30.

Normal and oncogenic roles for microRNAs in the developing brain.

Fernandez-L A, Northcott PA, Taylor MD, Kenney AM.

Cell Cycle. 2009 Dec 15;8(24):4049-54. Epub 2009 Dec 5.

PMID:
19901543
31.

Enteric neural crest differentiation in ganglioneuromas implicates Hedgehog signaling in peripheral neuroblastic tumor pathogenesis.

Gershon TR, Shiraz A, Qin LX, Gerald WL, Kenney AM, Cheung NK.

PLoS One. 2009 Oct 16;4(10):e7491. doi: 10.1371/journal.pone.0007491. Erratum in: PLoS One. 2014 Jul 25;9(7):e103881. Shirazi, Arash [corrected to Shiraz, Ashton].

32.

Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization.

Bhatia B, Northcott PA, Hambardzumyan D, Govindarajan B, Brat DJ, Arbiser JL, Holland EC, Taylor MD, Kenney AM.

Cancer Res. 2009 Sep 15;69(18):7224-34. doi: 10.1158/0008-5472.CAN-09-1299. Epub 2009 Sep 8.

33.

The miR-17/92 polycistron is up-regulated in sonic hedgehog-driven medulloblastomas and induced by N-myc in sonic hedgehog-treated cerebellar neural precursors.

Northcott PA, Fernandez-L A, Hagan JP, Ellison DW, Grajkowska W, Gillespie Y, Grundy R, Van Meter T, Rutka JT, Croce CM, Kenney AM, Taylor MD.

Cancer Res. 2009 Apr 15;69(8):3249-55. doi: 10.1158/0008-5472.CAN-08-4710. Epub 2009 Apr 7.

34.

Stabilization of N-Myc is a critical function of Aurora A in human neuroblastoma.

Otto T, Horn S, Brockmann M, Eilers U, Schüttrumpf L, Popov N, Kenney AM, Schulte JH, Beijersbergen R, Christiansen H, Berwanger B, Eilers M.

Cancer Cell. 2009 Jan 6;15(1):67-78. doi: 10.1016/j.ccr.2008.12.005.

35.

Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors.

Parathath SR, Mainwaring LA, Fernandez-L A, Campbell DO, Kenney AM.

Development. 2008 Oct;135(19):3291-300. doi: 10.1242/dev.022871. Epub 2008 Aug 28.

36.

Gli activity correlates with tumor grade in platelet-derived growth factor-induced gliomas.

Becher OJ, Hambardzumyan D, Fomchenko EI, Momota H, Mainwaring L, Bleau AM, Katz AM, Edgar M, Kenney AM, Cordon-Cardo C, Blasberg RG, Holland EC.

Cancer Res. 2008 Apr 1;68(7):2241-9. doi: 10.1158/0008-5472.CAN-07-6350.

37.

N-myc is an essential downstream effector of Shh signaling during both normal and neoplastic cerebellar growth.

Hatton BA, Knoepfler PS, Kenney AM, Rowitch DH, de Alborán IM, Olson JM, Eisenman RN.

Cancer Res. 2006 Sep 1;66(17):8655-61.

38.

N-myc can substitute for insulin-like growth factor signaling in a mouse model of sonic hedgehog-induced medulloblastoma.

Browd SR, Kenney AM, Gottfried ON, Yoon JW, Walterhouse D, Pedone CA, Fults DW.

Cancer Res. 2006 Mar 1;66(5):2666-72.

39.

Neural precursor cycling at sonic speed: N-Myc pedals, GSK-3 brakes.

Knoepfler PS, Kenney AM.

Cell Cycle. 2006 Jan;5(1):47-52. Epub 2006 Jan 1. Review.

PMID:
16322694
40.

The Cdk1 complex plays a prime role in regulating N-myc phosphorylation and turnover in neural precursors.

Sjostrom SK, Finn G, Hahn WC, Rowitch DH, Kenney AM.

Dev Cell. 2005 Sep;9(3):327-38.

41.

Subtracting the Math: prominin-positive cerebellar stem cells in white matter.

Kenney AM, Segal RA.

Nat Neurosci. 2005 Jun;8(6):699-701. No abstract available.

PMID:
15917830
42.

Synchronization of goat fibroblast cells at quiescent stage and determination of their transition from G0 to G1 by detection of cyclin D1 mRNA.

Memili E, Behboodi E, Overton SA, Kenney AM, O'Coin M, Zahedi A, Rowitch DH, Echelard Y.

Cloning Stem Cells. 2004;6(2):58-66.

PMID:
15268778
43.

Hedgehog and PI-3 kinase signaling converge on Nmyc1 to promote cell cycle progression in cerebellar neuronal precursors.

Kenney AM, Widlund HR, Rowitch DH.

Development. 2004 Jan;131(1):217-28. Epub 2003 Dec 3. Erratum in: Development. 2004 Jan;131(2):489.

44.

Development of mice expressing a single D-type cyclin.

Ciemerych MA, Kenney AM, Sicinska E, Kalaszczynska I, Bronson RT, Rowitch DH, Gardner H, Sicinski P.

Genes Dev. 2002 Dec 15;16(24):3277-89.

45.
46.

Into reproductive health.

Nazareno MI, Eleserio G, Kenney AM, Collado E.

Integration. 1998 Spring;(55):30-3.

PMID:
12294076
47.

Identification of genes expressed with temporal-spatial restriction to developing cerebellar neuron precursors by a functional genomic approach.

Zhao Q, Kho A, Kenney AM, Yuk Di DI, Kohane I, Rowitch DH.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5704-9. Erratum in: Proc Natl Acad Sci U S A 2002 Jun 11;99(12):8460.

48.
49.

Rescue of alpha-SNS sodium channel expression in small dorsal root ganglion neurons after axotomy by nerve growth factor in vivo.

Dib-Hajj SD, Black JA, Cummins TR, Kenney AM, Kocsis JD, Waxman SG.

J Neurophysiol. 1998 May;79(5):2668-76.

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