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Items: 35


Altered Cell-Cycle Control, Inflammation, and Adhesion in High-Risk Persistent Bronchial Dysplasia.

Merrick DT, Edwards MG, Franklin WA, Sugita M, Keith RL, Miller YE, Friedman MB, Dwyer-Nield LD, Tennis MA, O'Keefe MC, Donald EJ, Malloy JM, van Bokhoven A, Wilson S, Koch PJ, O'Shea C, Coldren C, Orlicky DJ, Lu X, Baron AE, Hickey G, Kennedy TC, Powell R, Heasley L, Bunn PA, Geraci M, Nemenoff RA.

Cancer Res. 2018 Sep 1;78(17):4971-4983. doi: 10.1158/0008-5472.CAN-17-3822. Epub 2018 Jul 11.


Persistence of Bronchial Dysplasia Is Associated with Development of Invasive Squamous Cell Carcinoma.

Merrick DT, Gao D, Miller YE, Keith RL, Baron AE, Feser W, Kennedy TC, Blatchford PJ, Braudrick S, Hirsch FR, Heasley L, Bunn PA Jr, Franklin WA.

Cancer Prev Res (Phila). 2016 Jan;9(1):96-104. doi: 10.1158/1940-6207.CAPR-15-0305. Epub 2015 Nov 5.


Endobronchial miRNAs as biomarkers in lung cancer chemoprevention.

Mascaux C, Feser WJ, Lewis MT, Barón AE, Coldren CD, Merrick DT, Kennedy TC, Eckelberger JI, Rozeboom LM, Franklin WA, Minna JD, Bunn PA, Miller YE, Keith RL, Hirsch FR.

Cancer Prev Res (Phila). 2013 Feb;6(2):100-8. doi: 10.1158/1940-6207.CAPR-12-0382. Epub 2012 Dec 26.


Non-invasive breath analysis of pulmonary nodules.

Peled N, Hakim M, Bunn PA Jr, Miller YE, Kennedy TC, Mattei J, Mitchell JD, Hirsch FR, Haick H.

J Thorac Oncol. 2012 Oct;7(10):1528-33.


Defining a gene promoter methylation signature in sputum for lung cancer risk assessment.

Leng S, Do K, Yingling CM, Picchi MA, Wolf HJ, Kennedy TC, Feser WJ, Baron AE, Franklin WA, Brock MV, Herman JG, Baylin SB, Byers T, Stidley CA, Belinsky SA.

Clin Cancer Res. 2012 Jun 15;18(12):3387-95. doi: 10.1158/1078-0432.CCR-11-3049. Epub 2012 Apr 17.


Oral iloprost improves endobronchial dysplasia in former smokers.

Keith RL, Blatchford PJ, Kittelson J, Minna JD, Kelly K, Massion PP, Franklin WA, Mao J, Wilson DO, Merrick DT, Hirsch FR, Kennedy TC, Bunn PA Jr, Geraci MW, Miller YE.

Cancer Prev Res (Phila). 2011 Jun;4(6):793-802. doi: 10.1158/1940-6207.CAPR-11-0057.


The detection of chromosomal aneusomy by fluorescence in situ hybridization in sputum predicts lung cancer incidence.

Varella-Garcia M, Schulte AP, Wolf HJ, Feser WJ, Zeng C, Braudrick S, Yin X, Hirsch FR, Kennedy TC, Keith RL, Barón AE, Belinsky SA, Miller YE, Byers T, Franklin WA.

Cancer Prev Res (Phila). 2010 Apr;3(4):447-53. doi: 10.1158/1940-6207.CAPR-09-0165. Epub 2010 Mar 23.


A randomized phase II chemoprevention trial of 13-CIS retinoic acid with or without alpha tocopherol or observation in subjects at high risk for lung cancer.

Kelly K, Kittelson J, Franklin WA, Kennedy TC, Klein CE, Keith RL, Dempsey EC, Lewis M, Jackson MK, Hirsch FR, Bunn PA, Miller YE.

Cancer Prev Res (Phila). 2009 May;2(5):440-9. doi: 10.1158/1940-6207.CAPR-08-0136. Epub 2009 Apr 28.


Sputum cytologic atypia predicts incident lung cancer: defining latency and histologic specificity.

Byers T, Wolf HJ, Franklin WA, Braudrick S, Merrick DT, Shroyer KR, Hirsch FR, Zeng C, Barón AE, Bunn PA, Miller YE, Kennedy TC.

Cancer Epidemiol Biomarkers Prev. 2008 Jan;17(1):158-62. doi: 10.1158/1055-9965.EPI-07-0436.


Bronchial epithelial Ki-67 index is related to histology, smoking, and gender, but not lung cancer or chronic obstructive pulmonary disease.

Miller YE, Blatchford P, Hyun DS, Keith RL, Kennedy TC, Wolf H, Byers T, Bunn PA Jr, Lewis MT, Franklin WA, Hirsch FR, Kittelson J.

Cancer Epidemiol Biomarkers Prev. 2007 Nov;16(11):2425-31.


Chromosomal aneusomy in bronchial high-grade lesions is associated with invasive lung cancer.

Jonsson S, Varella-Garcia M, Miller YE, Wolf HJ, Byers T, Braudrick S, Kiatsimkul P, Lewis M, Kennedy TC, Keith RL, Bjornsson J, McWilliams A, Lam S, Hirsch FR, Franklin WA.

Am J Respir Crit Care Med. 2008 Feb 1;177(3):342-7. Epub 2007 Nov 7.


Bronchial intraepithelial neoplasia/early central airways lung cancer: ACCP evidence-based clinical practice guidelines (2nd edition).

Kennedy TC, McWilliams A, Edell E, Sutedja T, Downie G, Yung R, Gazdar A, Mathur PN; American College of Chest Physicians.

Chest. 2007 Sep;132(3 Suppl):221S-233S.


Spectral karyotyping detects chromosome damage in bronchial cells of smokers and patients with cancer.

Varella-Garcia M, Chen L, Powell RL, Hirsch FR, Kennedy TC, Keith R, Miller YE, Mitchell JD, Franklin WA.

Am J Respir Crit Care Med. 2007 Sep 1;176(5):505-12. Epub 2007 Jun 28.


Lack of association between sputum atypia and chronic obstructive pulmonary disease mortality.

Miller YE, Vu KO, Kennedy TC, Hirsch FR, Petty TL, Bunn PA Jr, Keith RL, Franklin WA, Wolf HJ, Prindiville S, Byers T.

J Thorac Oncol. 2006 May;1(4):302-7.


Analysis of c-ErbB1/epidermal growth factor receptor and c-ErbB2/HER-2 expression in bronchial dysplasia: evaluation of potential targets for chemoprevention of lung cancer.

Merrick DT, Kittelson J, Winterhalder R, Kotantoulas G, Ingeberg S, Keith RL, Kennedy TC, Miller YE, Franklin WA, Hirsch FR.

Clin Cancer Res. 2006 Apr 1;12(7 Pt 1):2281-8.


Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort.

Belinsky SA, Liechty KC, Gentry FD, Wolf HJ, Rogers J, Vu K, Haney J, Kennedy TC, Hirsch FR, Miller Y, Franklin WA, Herman JG, Baylin SB, Bunn PA, Byers T.

Cancer Res. 2006 Mar 15;66(6):3338-44.


High prevalence of occult endobronchial malignancy in high risk patients with moderate sputum atypia.

Kennedy TC, Franklin WA, Prindiville SA, Cook R, Dempsey EC, Keith RL, Hirsch FR, Merrick TA, Shroyer KR, Petty TL, Byers T, Bunn PA Jr, Miller YE.

Lung Cancer. 2005 Aug;49(2):187-91. Epub 2005 Apr 14.


Overexpression of vascular endothelial growth factor and its receptors in bronchial dypslasia demonstrated by quantitative RT-PCR analysis.

Merrick DT, Haney J, Petrunich S, Sugita M, Miller YE, Keith RL, Kennedy TC, Franklin WA.

Lung Cancer. 2005 Apr;48(1):31-45.


Using molecular markers in sputum for the early detection of lung cancer: a review.

Kennedy TC, Hirsch FR.

Lung Cancer. 2004 Aug;45 Suppl 2:S21-7. Review.


High prevalence of endobronchial malignancy in high-risk patients with moderate dysplasia in sputum.

Kennedy TC, Franklin WA, Prindiville SA, Cook R, Dempsey EC, Keith RL, Hirsch FR, Merrick TA, Shroyer KR, Petty TL, Byers T, Bunn PA Jr, Miller YE.

Chest. 2004 May;125(5 Suppl):109S. No abstract available.


Sputum cytological atypia as a predictor of incident lung cancer in a cohort of heavy smokers with airflow obstruction.

Prindiville SA, Byers T, Hirsch FR, Franklin WA, Miller YE, Vu KO, Wolf HJ, Barón AE, Shroyer KR, Zeng C, Kennedy TC, Bunn PA.

Cancer Epidemiol Biomarkers Prev. 2003 Oct;12(10):987-93.


Fluorescence versus white-light bronchoscopy for detection of preneoplastic lesions: a randomized study.

Hirsch FR, Prindiville SA, Miller YE, Franklin WA, Dempsey EC, Murphy JR, Bunn PA Jr, Kennedy TC.

J Natl Cancer Inst. 2001 Sep 19;93(18):1385-91.


Angiogenic squamous dysplasia in bronchi of individuals at high risk for lung cancer.

Keith RL, Miller YE, Gemmill RM, Drabkin HA, Dempsey EC, Kennedy TC, Prindiville S, Franklin WA.

Clin Cancer Res. 2000 May;6(5):1616-25.


Screening for lung cancer revisited and the role of sputum cytology and fluorescence bronchoscopy in a high-risk group.

Kennedy TC, Miller Y, Prindiville S.

Chest. 2000 Apr;117(4 Suppl 1):72S-79S. Review.


Efficacy of two sputum collection techniques in patients with air flow obstruction.

Kennedy TC, Proudfoot SP, Piantadosi S, Wu L, Saccomanno G, Petty TL, Tockman MS.

Acta Cytol. 1999 Jul-Aug;43(4):630-6.


Novel inhibitors of fungal protein synthesis produced by a strain of Graphium putredinis. Isolation, characterisation and biological properties.

Kennedy TC, Webb G, Cannell RJ, Kinsman OS, Middleton RF, Sidebottom PJ, Taylor NL, Dawson MJ, Buss AD.

J Antibiot (Tokyo). 1998 Nov;51(11):1012-8.


Cytopathological analysis of sputum in patients with airflow obstruction and significant smoking histories.

Kennedy TC, Proudfoot SP, Franklin WA, Merrick TA, Saccomanno G, Corkill ME, Mumma DL, Sirgi KE, Miller YE, Archer PG, Prochazka A.

Cancer Res. 1996 Oct 15;56(20):4673-8.


Pulmonary hypertension associated with long-term inhalation of "crank" methamphetamine.

Schaiberger PH, Kennedy TC, Miller FC, Gal J, Petty TL.

Chest. 1993 Aug;104(2):614-6.


Interpretation of arterial blood gases by computer.

Broughton JO Jr, Kennedy TC.

Chest. 1984 Feb;85(2):148-9. No abstract available.


Effect of aging alone on mechanical properties of the normal adult human lung.

Knudson RJ, Clark DF, Kennedy TC, Knudson DE.

J Appl Physiol Respir Environ Exerc Physiol. 1977 Dec;43(6):1054-62.


Exercise-aggravated hypoxemia and orthodeoxia in cirrhosis.

Kennedy TC, Knudson RJ.

Chest. 1977 Sep;72(3):305-9.


A method of analysing hospital surgical waiting lists.

Kennedy TC.

Methods Inf Med. 1975 Jul;14(3):133-40. No abstract available.


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