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Ligand binding properties of two Brugia malayi fatty acid and retinol (FAR) binding proteins and their vaccine efficacies against challenge infection in gerbils.

Zhan B, Arumugam S, Kennedy MW, Tricoche N, Lian LY, Asojo OA, Bennuru S, Bottazzi ME, Hotez PJ, Lustigman S, Klei TR.

PLoS Negl Trop Dis. 2018 Oct 8;12(10):e0006772. doi: 10.1371/journal.pntd.0006772. eCollection 2018 Oct.


The house dust mite allergen Der p 5 binds lipid ligands and stimulates airway epithelial cells through a TLR2-dependent pathway.

Pulsawat P, Soongrung T, Satitsuksanoa P, Le Mignon M, Khemili S, Gilis D, Nony E, Kennedy MW, Jacquet A.

Clin Exp Allergy. 2018 Sep 19. doi: 10.1111/cea.13278. [Epub ahead of print]


Frog foams and natural protein surfactants.

Cooper A, Vance SJ, Smith BO, Kennedy MW.

Colloids Surf A Physicochem Eng Asp. 2017 Dec 5;534:120-129. doi: 10.1016/j.colsurfa.2017.01.049.


Rapid changes in Atlantic grey seal milk from birth to weaning - immune factors and indicators of metabolic strain.

Lowe AD, Bawazeer S, Watson DG, McGill S, Burchmore RJS, Pomeroy PPP, Kennedy MW.

Sci Rep. 2017 Nov 23;7(1):16093. doi: 10.1038/s41598-017-16187-7.


Identification and characterization of the major pseudocoelomic proteins of the giant kidney worm, Dioctophyme renale.

Giorello AN, Kennedy MW, Butti MJ, Radman NE, Córsico B, Franchini GR.

Parasit Vectors. 2017 Sep 27;10(1):446. doi: 10.1186/s13071-017-2388-x.


Everolimus-eluting bioresorbable vascular scaffold in daily clinical practice: A single-centre experience.

Remkes WS, Hermanides RS, Kennedy MW, Fabris E, Kaplan E, Ottervanger JP, van 't Hof AWJ, Kedhi E.

Neth Heart J. 2017 Nov;25(11):611-617. doi: 10.1007/s12471-017-1038-4.


Long-term mortality and prehospital tirofiban treatment in patients with ST elevation myocardial infarction.

Fabris E, Kilic S, Schellings DAAM, Ten Berg JM, Kennedy MW, van Houwelingen KG, Giannitsis E, Kolkman E, Ottervanger JP, Hamm C, Van't Hof AWJ.

Heart. 2017 Oct;103(19):1515-1520. doi: 10.1136/heartjnl-2017-311181. Epub 2017 Jul 5.


A prospective, randomized, open-label trial of 6-month versus 12-month dual antiplatelet therapy after drug-eluting stent implantation in ST-elevation myocardial infarction: Rationale and design of the "DAPT-STEMI trial".

Kedhi E, Fabris E, van der Ent M, Kennedy MW, Buszman P, von Birgelen C, Cook S, Wedel H, Zijlstra F.

Am Heart J. 2017 Jun;188:11-17. doi: 10.1016/j.ahj.2017.02.018. Epub 2017 Feb 20.


Is ischemia the only factor predicting cardiovascular outcomes in all diabetes mellitus patients?

Kennedy MW, Fabris E, Suryapranata H, Kedhi E.

Cardiovasc Diabetol. 2017 Apr 20;16(1):51. doi: 10.1186/s12933-017-0533-7. Review.


Pulse of inflammatory proteins in the pregnant uterus of European polecats (Mustela putorius) leading to the time of implantation.

Lindeberg H, Burchmore RJ, Kennedy MW.

R Soc Open Sci. 2017 Mar 22;4(3):161085. doi: 10.1098/rsos.161085. eCollection 2017 Mar.


Optical coherence tomography for strategy planning and staged optimization of spontaneous coronary artery dissection.

Fabris E, Kennedy MW, Sinagra G, Van't Hof A, Kedhi E.

Eur Heart J Cardiovasc Imaging. 2017 May 1;18(8):939. doi: 10.1093/ehjci/jex058. No abstract available.


Factors associated with deferred lesion failure following fractional flow reserve assessment in patients with diabetes mellitus.

Kennedy MW, Fabris E, Hermanides RS, Kaplan E, Borren N, Berta B, Koopmans PC, Ottervanger JP, Suryapranata H, Kedhi E.

Catheter Cardiovasc Interv. 2017 Dec 1;90(7):1077-1083. doi: 10.1002/ccd.27002. Epub 2017 Mar 17.


Adsorption of the natural protein surfactant Rsn-2 onto liquid interfaces.

Brandani GB, Vance SJ, Schor M, Cooper A, Kennedy MW, Smith BO, MacPhee CE, Cheung DL.

Phys Chem Chem Phys. 2017 Mar 22;19(12):8584-8594. doi: 10.1039/c6cp07261e.


International Subspecialty Fellowship Training, the Path for Cardiologists of Tomorrow?: A European Perspective.

Fabris E, Kennedy MW.

J Am Coll Cardiol. 2017 Mar 7;69(9):1200-1203. doi: 10.1016/j.jacc.2017.01.021. No abstract available.


Changeover from signalling to energy-provisioning lipids during transition from colostrum to mature milk in the giant panda (Ailuropoda melanoleuca).

Zhang T, Watson DG, Zhang R, Hou R, Loeffler IK, Kennedy MW.

Sci Rep. 2016 Nov 3;6:36141. doi: 10.1038/srep36141.


Fractional Flow Reserve-Guided Deferred Versus Complete Revascularization in Patients With Diabetes Mellitus.

Kennedy MW, Hermanides RS, Kaplan E, Hemradj V, Fabris E, Koopmans PC, Dambrink JE, Gosselink AT, Van't Hof AW, Ottervanger JP, Roolvink V, Remkes WS, van der Sluis A, Suryapranata H, Kedhi E.

Am J Cardiol. 2016 Nov 1;118(9):1293-1299. doi: 10.1016/j.amjcard.2016.07.059. Epub 2016 Aug 13.


Combined optical coherence tomography morphologic and fractional flow reserve hemodynamic assessment of non- culprit lesions to better predict adverse event outcomes in diabetes mellitus patients: COMBINE (OCT-FFR) prospective study. Rationale and design.

Kennedy MW, Fabris E, Ijsselmuiden AJ, Nef H, Reith S, Escaned J, Alfonso F, van Royen N, Wojakowski W, Witkowski A, Indolfi C, Ottervanger JP, Suryapranata H, Kedhi E.

Cardiovasc Diabetol. 2016 Oct 10;15(1):144.


Guide extension, unmissable tool in the armamentarium of modern interventional cardiology. A comprehensive review.

Fabris E, Kennedy MW, Di Mario C, Sinagra G, Roolvink V, Ottervanger JP, Van't Hof AWJ, Kedhi E.

Int J Cardiol. 2016 Nov 1;222:141-147. doi: 10.1016/j.ijcard.2016.07.168. Epub 2016 Jul 29. Review.


Clinical outcomes of deferred revascularisation using fractional flow reserve in patients with and without diabetes mellitus.

Kennedy MW, Kaplan E, Hermanides RS, Fabris E, Hemradj V, Koopmans PC, Dambrink JH, Marcel Gosselink AT, Van't Hof AW, Ottervanger JP, Roolvink V, Remkes WS, van der Sluis A, Suryapranata H, Kedhi E.

Cardiovasc Diabetol. 2016 Jul 19;15:100. doi: 10.1186/s12933-016-0417-2.


A new gain-of-function mouse line to study the role of Wnt3a in development and disease.

Chalamalasetty RB, Ajima R, Garriock RJ, Kennedy MW, Tessarollo L, Yamaguchi TP.

Genesis. 2016 Sep;54(9):497-502. doi: 10.1002/dvg.22959. Epub 2016 Jul 26.


Impact of TCFA on Unanticipated Ischemic Events in Medically Treated Diabetes Mellitus: Insights From the PROSPECT Study.

Kedhi E, Kennedy MW, Maehara A, Lansky AJ, McAndrew TC, Marso SP, De Bruyne B, Serruys PW, Stone GW.

JACC Cardiovasc Imaging. 2017 Apr;10(4):451-458. doi: 10.1016/j.jcmg.2015.12.023. Epub 2016 Jun 29.


Aqueous solubilization of C60 fullerene by natural protein surfactants, latherin and ranaspumin-2.

Vance SJ, Desai V, Smith BO, Kennedy MW, Cooper A.

Biophys Chem. 2016 Jul-Aug;214-215:27-32. doi: 10.1016/j.bpc.2016.05.003. Epub 2016 May 13.


Zfp703 Is a Wnt/β-Catenin Feedback Suppressor Targeting the β-Catenin/Tcf1 Complex.

Kumar A, Chalamalasetty RB, Kennedy MW, Thomas S, Inala SN, Garriock RJ, Yamaguchi TP.

Mol Cell Biol. 2016 May 31;36(12):1793-802. doi: 10.1128/MCB.01010-15. Print 2016 Jun 15.


Effects of Filtering the Center of Pressure Feedback Provided in Visually Guided Mediolateral Weight Shifting.

Kennedy MW, Crowell CR, Villano M, Schmiedeler JP.

PLoS One. 2016 Mar 18;11(3):e0151393. doi: 10.1371/journal.pone.0151393. eCollection 2016.


Sp5 and Sp8 recruit β-catenin and Tcf1-Lef1 to select enhancers to activate Wnt target gene transcription.

Kennedy MW, Chalamalasetty RB, Thomas S, Garriock RJ, Jailwala P, Yamaguchi TP.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):3545-50. doi: 10.1073/pnas.1519994113. Epub 2016 Mar 11.


Changes in the Milk Metabolome of the Giant Panda (Ailuropoda melanoleuca) with Time after Birth--Three Phases in Early Lactation and Progressive Individual Differences.

Zhang T, Zhang R, Zhang L, Zhang Z, Hou R, Wang H, Loeffler IK, Watson DG, Kennedy MW.

PLoS One. 2015 Dec 2;10(12):e0143417. doi: 10.1371/journal.pone.0143417. eCollection 2015.


Prolonged transition time between colostrum and mature milk in a bear, the giant panda, Ailuropoda melanoleuca.

Griffiths K, Hou R, Wang H, Zhang Z, Zhang L, Zhang T, Watson DG, Burchmore RJ, Loeffler IK, Kennedy MW.

R Soc Open Sci. 2015 Oct 21;2(10):150395. doi: 10.1098/rsos.150395. eCollection 2015 Oct.


Diversity in the structures and ligand-binding sites of nematode fatty acid and retinol-binding proteins revealed by Na-FAR-1 from Necator americanus.

Rey-Burusco MF, Ibáñez-Shimabukuro M, Gabrielsen M, Franchini GR, Roe AJ, Griffiths K, Zhan B, Cooper A, Kennedy MW, Córsico B, Smith BO.

Biochem J. 2015 Nov 1;471(3):403-14. doi: 10.1042/BJ20150068. Epub 2015 Aug 28.


Core and body surface temperatures of nesting leatherback turtles (Dermochelys coriacea).

Burns TJ, McCafferty DJ, Kennedy MW.

J Therm Biol. 2015 Jul;51:15-22. doi: 10.1016/j.jtherbio.2015.03.001. Epub 2015 Mar 3.


Lineage tracing of neuromesodermal progenitors reveals novel Wnt-dependent roles in trunk progenitor cell maintenance and differentiation.

Garriock RJ, Chalamalasetty RB, Kennedy MW, Canizales LC, Lewandoski M, Yamaguchi TP.

Development. 2015 May 1;142(9):1628-38. doi: 10.1242/dev.111922.


Lipid-free antigen B subunits from echinococcus granulosus: oligomerization, ligand binding, and membrane interaction properties.

Silva-Álvarez V, Franchini GR, Pórfido JL, Kennedy MW, Ferreira AM, Córsico B.

PLoS Negl Trop Dis. 2015 Mar 13;9(3):e0003552. doi: 10.1371/journal.pntd.0003552. eCollection 2015 Mar.


IgE responses to Ascaris and mite tropomyosins are risk factors for asthma.

Ahumada V, García E, Dennis R, Rojas MX, Rondón MA, Pérez A, Peñaranda A, Barragán AM, Jimenez S, Kennedy MW, Caraballo L.

Clin Exp Allergy. 2015 Jul;45(7):1189-200. doi: 10.1111/cea.12513.


Mesogenin 1 is a master regulator of paraxial presomitic mesoderm differentiation.

Chalamalasetty RB, Garriock RJ, Dunty WC Jr, Kennedy MW, Jailwala P, Si H, Yamaguchi TP.

Development. 2014 Nov;141(22):4285-97. doi: 10.1242/dev.110908.


The unusual lipid binding proteins of parasitic helminths and their potential roles in parasitism and as therapeutic targets.

Franchini GR, Pórfido JL, Ibáñez Shimabukuro M, Rey Burusco MF, Bélgamo JA, Smith BO, Kennedy MW, Córsico B.

Prostaglandins Leukot Essent Fatty Acids. 2015 Feb;93:31-6. doi: 10.1016/j.plefa.2014.08.003. Epub 2014 Aug 28. Review.


Interpreting lateral dynamic weight shifts using a simple inverted pendulum model.

Kennedy MW, Bretl T, Schmiedeler JP.

Gait Posture. 2014;40(1):134-9. doi: 10.1016/j.gaitpost.2014.03.011. Epub 2014 Mar 15.


Transcriptional profiling of Wnt3a mutants identifies Sp transcription factors as essential effectors of the Wnt/β-catenin pathway in neuromesodermal stem cells.

Dunty WC Jr, Kennedy MW, Chalamalasetty RB, Campbell K, Yamaguchi TP.

PLoS One. 2014 Jan 24;9(1):e87018. doi: 10.1371/journal.pone.0087018. eCollection 2014. Erratum in: PLoS One. 2014;9(4):e95947.


Relative efficacy of various strategies for visual feedback in standing balance activities.

Kennedy MW, Crowell CR, Striegel AD, Villano M, Schmiedeler JP.

Exp Brain Res. 2013 Sep;230(1):117-25. doi: 10.1007/s00221-013-3634-x. Epub 2013 Jul 9.


The structure of latherin, a surfactant allergen protein from horse sweat and saliva.

Vance SJ, McDonald RE, Cooper A, Smith BO, Kennedy MW.

J R Soc Interface. 2013 Jun 19;10(85):20130453. doi: 10.1098/rsif.2013.0453. Print 2013 Aug 6.


Resonance assignments for latherin, a natural surfactant protein from horse sweat.

Vance SJ, McDonald RE, Cooper A, Kennedy MW, Smith BO.

Biomol NMR Assign. 2014 Apr;8(1):213-6. doi: 10.1007/s12104-013-9485-3. Epub 2013 May 26.


Proteomics as a tool to explore human milk in health and disease.

Roncada P, Stipetic LH, Bonizzi L, Burchmore RJ, Kennedy MW.

J Proteomics. 2013 Aug 2;88:47-57. doi: 10.1016/j.jprot.2013.04.008. Epub 2013 Apr 13. Review.


Resonance assignment of As-p18, a fatty acid binding protein secreted by developing larvae of the parasitic nematode Ascaris suum.

Ibáñez-Shimabukuro M, Rey-Burusco MF, Cooper A, Kennedy MW, Córsico B, Smith BO.

Biomol NMR Assign. 2014 Apr;8(1):33-6. doi: 10.1007/s12104-012-9447-1. Epub 2012 Dec 6.


¹H, ¹³C and ¹⁵N chemical shift assignments of Na-FAR-1, a helix-rich fatty acid and retinol binding protein of the parasitic nematode Necator americanus.

Rey-Burusco MF, Ibañez-Shimabukuro M, Cooper A, Kennedy MW, Córsico B, Smith BO.

Biomol NMR Assign. 2014 Apr;8(1):19-21. doi: 10.1007/s12104-012-9444-4. Epub 2012 Nov 20.


Direct interaction between EgFABP1, a fatty acid binding protein from Echinococcus granulosus, and phospholipid membranes.

Porfido JL, Alvite G, Silva V, Kennedy MW, Esteves A, Corsico B.

PLoS Negl Trop Dis. 2012;6(11):e1893. doi: 10.1371/journal.pntd.0001893. Epub 2012 Nov 15.


Useable diffraction data from a multiple microdomain-containing crystal of Ascaris suum As-p18 fatty-acid-binding protein using a microfocus beamline.

Gabrielsen M, Riboldi-Tunnicliffe A, Ibáñez-Shimabukuro M, Griffiths K, Roe AJ, Cooper A, Smith BO, Córsico B, Kennedy MW.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Aug 1;68(Pt 8):939-41. doi: 10.1107/S1744309112026553. Epub 2012 Jul 31.


Two crystal forms of a helix-rich fatty acid- and retinol-binding protein, Na-FAR-1, from the parasitic nematode Necator americanus.

Gabrielsen M, Rey-Burusco MF, Griffiths K, Roe AJ, Cooper A, Smith BO, Kennedy MW, Corsico B.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Jul 1;68(Pt 7):835-8. doi: 10.1107/S1744309112023597. Epub 2012 Jun 28.


Latherin and other biocompatible surfactant proteins.

Kennedy MW.

Biochem Soc Trans. 2011 Aug;39(4):1017-22. doi: 10.1042/BST0391017.


The polyprotein allergens of nematodes (NPAs) - structure at last, but still mysterious.

Kennedy MW.

Exp Parasitol. 2011 Oct;129(2):81-4. doi: 10.1016/j.exppara.2011.06.007. Epub 2011 Jun 29. Review.


Solution structure of a repeated unit of the ABA-1 nematode polyprotein allergen of Ascaris reveals a novel fold and two discrete lipid-binding sites.

Meenan NA, Ball G, Bromek K, Uhrín D, Cooper A, Kennedy MW, Smith BO.

PLoS Negl Trop Dis. 2011 Apr 19;5(4):e1040. doi: 10.1371/journal.pntd.0001040.


Xrel3/XrelA attenuates β-catenin-mediated transcription during mesoderm formation in Xenopus embryos.

Kennedy MW, Kao KR.

Biochem J. 2011 Apr 1;435(1):247-57. doi: 10.1042/BJ20101801.


Biofoams and natural protein surfactants.

Cooper A, Kennedy MW.

Biophys Chem. 2010 Oct;151(3):96-104. doi: 10.1016/j.bpc.2010.06.006. Epub 2010 Jun 25. Review.

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