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Items: 1 to 50 of 404

1.

Targeted drug delivery via caveolae-associated protein PV1 improves lung fibrosis.

Marchetti GM, Burwell TJ, Peterson NC, Cann JA, Hanna RN, Li Q, Ongstad EL, Boyd JT, Kennedy MA, Zhao W, Rickert KW, Grimsby JS, Dall'Acqua WF, Wu H, Tsui P, Borrok MJ, Gupta R.

Commun Biol. 2019 Mar 7;2:92. doi: 10.1038/s42003-019-0337-2. eCollection 2019.

2.

RANCM: a new ranking scheme for assigning confidence levels to metabolite assignments in NMR-based metabolomics studies.

Joesten WC, Kennedy MA.

Metabolomics. 2019 Jan 3;15(1):5. doi: 10.1007/s11306-018-1465-2.

PMID:
30830432
3.

Evaluation of the Antibacterial Activity of 75 Mushrooms Collected in the Vicinity of Oxford, Ohio (USA).

Hassan F, Ni S, Becker TL, Kinstedt CM, Abdul-Samad JL, Actis LA, Kennedy MA.

Int J Med Mushrooms. 2019;21(2):131-141. doi: 10.1615/IntJMedMushrooms.2018029710.

PMID:
30806220
4.

Friends, family, and boyfriends: An analysis of relationship pathways into commercial sexual exploitation.

Reed SM, Kennedy MA, Decker MR, Cimino AN.

Child Abuse Negl. 2019 Apr;90:1-12. doi: 10.1016/j.chiabu.2019.01.016. Epub 2019 Jan 30.

PMID:
30716650
5.

A Tie2 kinase mutation causing venous malformations increases phosphorylation rates and enhances cooperativity.

Kennedy MA, Xu Z, Wu Y, Sohl CD.

Biochem Biophys Res Commun. 2019 Feb 19;509(4):898-902. doi: 10.1016/j.bbrc.2019.01.020. Epub 2019 Jan 11.

PMID:
30638931
6.

The Potential for Cancer Immunotherapy in Targeting Surgery-Induced Natural Killer Cell Dysfunction.

Market M, Baxter KE, Angka L, Kennedy MA, Auer RC.

Cancers (Basel). 2018 Dec 20;11(1). pii: E2. doi: 10.3390/cancers11010002. Review.

7.

Gene expression effects of lithium and valproic acid in a serotonergic cell line.

Balasubramanian D, Pearson JF, Kennedy MA.

Physiol Genomics. 2019 Feb 1;51(2):43-50. doi: 10.1152/physiolgenomics.00069.2018. Epub 2018 Dec 21.

PMID:
30576260
8.

Pharmacogenetics of angiotensin-converting enzyme inhibitor-induced angioedema.

Liau Y, Chua I, Kennedy MA, Maggo S.

Clin Exp Allergy. 2019 Feb;49(2):142-154. doi: 10.1111/cea.13326. Epub 2019 Jan 8. Review.

PMID:
30537422
9.

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, Degenhardt F, Docherty AR, Edwards AC, Fontanillas P, Foo JC, Fox L, Frank J, Giegling I, Gordon S, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Jan Hottenga J, Kennedy MA, Alanne-Kinnunen M, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Pearson JF, Peterson RE, Ripatti S, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG; 23andMe Research Team, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye MA, Gäbel W, Hayward C, Ising M, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Palotie A, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins DE, Boden JM, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Cichon S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Nöthen MM, Palmer AA, Pedersen NL, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A.

Nat Neurosci. 2018 Dec;21(12):1656-1669. doi: 10.1038/s41593-018-0275-1. Epub 2018 Nov 26.

PMID:
30482948
10.

Solution NMR structure of CHU_1110 from Cytophaga hutchinsonii, an AHSA1 protein potentially involved in metal ion stress response.

Liang C, Zhu J, Ramelot TA, Kennedy MA, Yue X, Li X, Liu M, He T, Yang Y.

Proteins. 2019 Jan;87(1):91-95. doi: 10.1002/prot.25622. Epub 2018 Nov 11.

PMID:
30368907
11.

Bridging the gap between clinicians and fitness professionals: a challenge to implementing exercise as medicine.

Pojednic R, Bantham A, Arnstein F, Kennedy MA, Phillips E.

BMJ Open Sport Exerc Med. 2018 Oct 16;4(1):e000369. doi: 10.1136/bmjsem-2018-000369. eCollection 2018.

12.

Penetrance and expressivity of the R858H CACNA1C variant in a five-generation pedigree segregating an arrhythmogenic channelopathy.

Gardner RJM, Crozier IG, Binfield AL, Love DR, Lehnert K, Gibson K, Lintott CJ, Snell RG, Jacobsen JC, Jones PP, Waddell-Smith KE, Kennedy MA, Skinner JR.

Mol Genet Genomic Med. 2019 Jan;7(1):e00476. doi: 10.1002/mgg3.476. Epub 2018 Oct 21.

13.

The Anorexia Nervosa Genetics Initiative (ANGI): Overview and methods.

Thornton LM, Munn-Chernoff MA, Baker JH, Juréus A, Parker R, Henders AK, Larsen JT, Petersen L, Watson HJ, Yilmaz Z, Kirk KM, Gordon S, Leppä VM, Martin FC, Whiteman DC, Olsen CM, Werge TM, Pedersen NL, Kaye W, Bergen AW, Halmi KA, Strober M, Kaplan AS, Woodside DB, Mitchell J, Johnson CL, Brandt H, Crawford S, Horwood LJ, Boden JM, Pearson JF, Duncan LE, Grove J, Mattheisen M, Jordan J, Kennedy MA, Birgegård A, Lichtenstein P, Norring C, Wade TD, Montgomery GW, Martin NG, Landén M, Mortensen PB, Sullivan PF, Bulik CM.

Contemp Clin Trials. 2018 Nov;74:61-69. doi: 10.1016/j.cct.2018.09.015. Epub 2018 Oct 1.

14.

Can we predict treatment response in children with ADHD to a vitamin-mineral supplement? An investigation into pre-treatment nutrient serum levels, MTHFR status, clinical correlates and demographic variables.

Rucklidge JJ, Eggleston MJF, Darling KA, Stevens AJ, Kennedy MA, Frampton CM.

Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:181-192. doi: 10.1016/j.pnpbp.2018.09.007. Epub 2018 Sep 12.

PMID:
30217770
15.

Natural Killer Cell IFNγ Secretion is Profoundly Suppressed Following Colorectal Cancer Surgery.

Angka L, Martel AB, Kilgour M, Jeong A, Sadiq M, de Souza CT, Baker L, Kennedy MA, Kekre N, Auer RC.

Ann Surg Oncol. 2018 Nov;25(12):3747-3754. doi: 10.1245/s10434-018-6691-3. Epub 2018 Sep 5.

PMID:
30187278
16.

Methylomic changes in response to micronutrient supplementation and MTHFR genotype.

Stevens AJ, Rucklidge JJ, Darling KA, Eggleston MJ, Pearson JF, Kennedy MA.

Epigenomics. 2018 Sep;10(9):1201-1214. doi: 10.2217/epi-2018-0029. Epub 2018 Sep 5.

17.

Solution structure of SHIP2 SH2 domain and its interaction with a phosphotyrosine peptide from c-MET.

Wang Z, Nie Y, Zhang K, Xu H, Ramelot TA, Kennedy MA, Liu M, Zhu J, Yang Y.

Arch Biochem Biophys. 2018 Oct 15;656:31-37. doi: 10.1016/j.abb.2018.08.012. Epub 2018 Aug 27.

PMID:
30165040
18.

A genome project for Māori and Pasifika: charting a path to equity in genomic medicine for Aotearoa.

Kennedy MA.

N Z Med J. 2018 Aug 17;131(1480):8-10. No abstract available.

PMID:
30116058
19.

Testicular Cancer in New Zealand (TCNZ) study: protocol for a national case-control study.

Gurney JK, Stanley J, McGlynn K, Richiardi L, Shaw C, Edwards R, Merriman TR, Robson B, Koea J, McLeod M, Kennedy MA, Sarfati D.

BMJ Open. 2018 Aug 5;8(8):e025212. doi: 10.1136/bmjopen-2018-025212.

20.

NMR-based metabolic profiling of urine, serum, fecal, and pancreatic tissue samples from the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer.

Schmahl MJ, Regan DP, Rivers AC, Joesten WC, Kennedy MA.

PLoS One. 2018 Jul 17;13(7):e0200658. doi: 10.1371/journal.pone.0200658. eCollection 2018.

21.

NMR-based urine metabolic profiling and immunohistochemistry analysis of nephron changes in a mouse model of hypoxia-induced acute kidney injury.

Chihanga T, Ruby HN, Ma Q, Bashir S, Devarajan P, Kennedy MA.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F1159-F1173. doi: 10.1152/ajprenal.00500.2017. Epub 2018 Jul 11.

PMID:
29993280
22.

Phosphodiesterase-5 inhibition reduces postoperative metastatic disease by targeting surgery-induced myeloid derived suppressor cell-dependent inhibition of Natural Killer cell cytotoxicity.

Tai LH, Alkayyal AA, Leslie AL, Sahi S, Bennett S, Tanese de Souza C, Baxter K, Angka L, Xu R, Kennedy MA, Auer RC.

Oncoimmunology. 2018 Mar 1;7(6):e1431082. doi: 10.1080/2162402X.2018.1431082. eCollection 2018.

23.

Nonsynonymous Polymorphism in Guanine Monophosphate Synthetase Is a Risk Factor for Unfavorable Thiopurine Metabolite Ratios in Patients With Inflammatory Bowel Disease.

Roberts RL, Wallace MC, Seinen ML, van Bodegraven AA, Krishnaprasad K, Jones GT, van Rij AM, Baird A, Lawrance IC, Prosser R, Bampton P, Grafton R, Simms LA, Studd C, Bell SJ, Kennedy MA, Halliwell J, Gearry RB, Radford-Smith G, Andrews JM, McHugh PC, Barclay ML.

Inflamm Bowel Dis. 2018 Nov 29;24(12):2606-2612. doi: 10.1093/ibd/izy163.

PMID:
29788244
24.

Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy.

Lacey CJ, Doudney K, Bridgman PG, George PM, Mulder RT, Zarifeh JJ, Kimber B, Cadzow MJ, Black MA, Merriman TR, Lehnert K, Bickley VM, Pearson JF, Cameron VA, Kennedy MA.

Sci Rep. 2018 May 15;8(1):7548. doi: 10.1038/s41598-018-25827-5.

25.

Multiplexed Nanopore Sequencing of HLA-B Locus in Māori and Pacific Island Samples.

Ton KNT, Cree SL, Gronert-Sum SJ, Merriman TR, Stamp LK, Kennedy MA.

Front Genet. 2018 Apr 30;9:152. doi: 10.3389/fgene.2018.00152. eCollection 2018.

26.

Inter-individual variation in imatinib disposition: any role for prevalent variants of CYP1A2, CYP2C8, CYP2C9, and CYP3A5 in Nigerian CML patients?

Adehin A, Adeagbo BA, Kennedy MA, Bolaji OO, Olugbade TA, Bolarinwa RA, Durosinmi MA.

Leuk Lymphoma. 2019 Jan;60(1):216-221. doi: 10.1080/10428194.2018.1466291. Epub 2018 May 9.

PMID:
29741432
27.

Correction to: Sepsis increases perioperative metastases in a murine model.

Tai LH, Ananth AA, Seth R, Alkayyal A, Zhang J, de Souza CT, Staibano P, Kennedy MA, Auer RC.

BMC Cancer. 2018 Apr 17;18(1):437. doi: 10.1186/s12885-018-4248-2.

28.

Sepsis increases perioperative metastases in a murine model.

Tai LH, Ananth AA, Seth R, Alkayyal A, Zhang J, de Souza CT, Staibano P, Kennedy MA, Auer RC.

BMC Cancer. 2018 Mar 12;18(1):277. doi: 10.1186/s12885-018-4173-4. Erratum in: BMC Cancer. 2018 Apr 17;18(1):437.

29.

Adenovirus-Mediated Delivery of Decoy Hyper Binding Sites Targeting Oncogenic HMGA1 Reduces Pancreatic and Liver Cancer Cell Viability.

Hassan F, Ni S, Arnett TC, McKell MC, Kennedy MA.

Mol Ther Oncolytics. 2018 Jan 31;8:52-61. doi: 10.1016/j.omto.2018.01.002. eCollection 2018 Mar 30.

30.
31.

Influence of media selection on NMR based metabolic profiling of human cell lines.

Chihanga T, Hausmann SM, Ni S, Kennedy MA.

Metabolomics. 2018 Jan 31;14(3):28. doi: 10.1007/s11306-018-1323-2.

PMID:
30830358
32.

Structural insights into the impact of two holoprosencephaly-related mutations on human TGIF1 homeodomain.

Zhu J, Li S, Ramelot TA, Kennedy MA, Liu M, Yang Y.

Biochem Biophys Res Commun. 2018 Feb 5;496(2):575-581. doi: 10.1016/j.bbrc.2018.01.099.

PMID:
29355528
33.

Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.

Xu S, Long BN, Boris GH, Chen A, Ni S, Kennedy MA.

Acta Crystallogr D Struct Biol. 2017 Dec 1;73(Pt 12):970-984. doi: 10.1107/S2059798317015418. Epub 2017 Nov 10.

PMID:
29199977
34.

A New Zealand platform to enable genetic investigation of adverse drug reactions.

Maggo SD, Chua EW, Chin P, Cree S, Pearson J, Doogue M, Kennedy MA.

N Z Med J. 2017 Dec 1;130(1466):62-69.

PMID:
29197902
35.

Nanopore sequencing of full-length BRCA1 mRNA transcripts reveals co-occurrence of known exon skipping events.

de Jong LC, Cree S, Lattimore V, Wiggins GAR, Spurdle AB; kConFab Investigators, Miller A, Kennedy MA, Walker LC.

Breast Cancer Res. 2017 Nov 28;19(1):127. doi: 10.1186/s13058-017-0919-1.

36.

Structural basis of glycan specificity of P[19] VP8*: Implications for rotavirus zoonosis and evolution.

Liu Y, Xu S, Woodruff AL, Xia M, Tan M, Kennedy MA, Jiang X.

PLoS Pathog. 2017 Nov 14;13(11):e1006707. doi: 10.1371/journal.ppat.1006707. eCollection 2017 Nov.

37.
38.

NMR spectroscopy and electron microscopy identification of metabolic and ultrastructural changes to the kidney following ischemia-reperfusion injury.

Chihanga T, Ma Q, Nicholson JD, Ruby HN, Edelmann RE, Devarajan P, Kennedy MA.

Am J Physiol Renal Physiol. 2018 Feb 1;314(2):F154-F166. doi: 10.1152/ajprenal.00363.2017. Epub 2017 Oct 4.

39.

Dissection of the Mouse Pancreas for Histological Analysis and Metabolic Profiling.

Veite-Schmahl MJ, Regan DP, Rivers AC, Nowatzke JF, Kennedy MA.

J Vis Exp. 2017 Aug 19;(126). doi: 10.3791/55647.

40.

Chemical shift assignments of Mb1858 (24-155), a FHA domain-containing protein from Mycobacterium bovis.

He T, Li S, Hu R, Ramelot TA, Kennedy MA, Yang Y, Zhu J, Liu M.

Biomol NMR Assign. 2018 Apr;12(1):1-4. doi: 10.1007/s12104-017-9769-0. Epub 2017 Aug 30.

PMID:
28856609
41.

Chemical shift assignments of polyketide cyclase_like protein CGL2373 from Corynebacterium glutamicum.

Liang C, Hu R, Ramelot TA, Kennedy MA, Li X, Yang Y, Zhu J, Liu M.

Biomol NMR Assign. 2017 Oct;11(2):289-292. doi: 10.1007/s12104-017-9765-4. Epub 2017 Aug 20.

PMID:
28825188
42.

Dysfunctional Natural Killer Cells in the Aftermath of Cancer Surgery.

Angka L, Khan ST, Kilgour MK, Xu R, Kennedy MA, Auer RC.

Int J Mol Sci. 2017 Aug 17;18(8). pii: E1787. doi: 10.3390/ijms18081787. Review.

43.

Symmetry broken and rebroken during the ATP hydrolysis cycle of the mitochondrial Hsp90 TRAP1.

Elnatan D, Betegon M, Liu Y, Ramelot T, Kennedy MA, Agard DA.

Elife. 2017 Jul 25;6. pii: e25235. doi: 10.7554/eLife.25235.

44.

HMGA1 expression levels are elevated in pancreatic intraepithelial neoplasia cells in the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer.

Veite-Schmahl MJ, Joesten WC, Kennedy MA.

Br J Cancer. 2017 Aug 22;117(5):639-647. doi: 10.1038/bjc.2017.216. Epub 2017 Jul 11.

45.

Methylated Cytosine Maintains G-Quadruplex Structures during Polymerase Chain Reaction and Contributes to Allelic Dropout.

Stevens AJ, Kennedy MA.

Biochemistry. 2017 Jul 25;56(29):3691-3698. doi: 10.1021/acs.biochem.7b00480. Epub 2017 Jul 10.

PMID:
28692286
46.

NMR characterization of HtpG, the E. coli Hsp90, using sparse labeling with 13C-methyl alanine.

Pederson K, Chalmers GR, Gao Q, Elnatan D, Ramelot TA, Ma LC, Montelione GT, Kennedy MA, Agard DA, Prestegard JH.

J Biomol NMR. 2017 Jul;68(3):225-236. doi: 10.1007/s10858-017-0123-8. Epub 2017 Jun 26.

47.

Epigenetics, nutrition and mental health. Is there a relationship?

Stevens AJ, Rucklidge JJ, Kennedy MA.

Nutr Neurosci. 2018 Nov;21(9):602-613. doi: 10.1080/1028415X.2017.1331524. Epub 2017 May 29. Review.

PMID:
28553986
48.

Long Fragment Polymerase Chain Reaction.

Chua EW, Maggo S, Kennedy MA.

Methods Mol Biol. 2017;1620:65-74. doi: 10.1007/978-1-4939-7060-5_3.

PMID:
28540699
49.

NMR Analysis of Amide Hydrogen Exchange Rates in a Pentapeptide-Repeat Protein from A. thaliana.

Xu S, Ni S, Kennedy MA.

Biophys J. 2017 May 23;112(10):2075-2088. doi: 10.1016/j.bpj.2017.04.016.

50.

Childhood Maltreatment and Child Protective Services Involvement Among the Commercially Sexually Exploited: A Comparison of Women Who Enter as Juveniles or as Adults.

Cimino AN, Madden EE, Hohn K, Cronley CM, Davis JB, Magruder K, Kennedy MA.

J Child Sex Abus. 2017 Apr;26(3):352-371. doi: 10.1080/10538712.2017.1282575.

PMID:
28471337

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