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Items: 1 to 50 of 416

1.

The Three Ps: Psychiatry, Pharmacy, and Pharmacogenomics, a Brief Report From New Zealand.

Maggo SDS, Sycamore KLV, Miller AL, Kennedy MA.

Front Psychiatry. 2019 Sep 20;10:690. doi: 10.3389/fpsyt.2019.00690. eCollection 2019.

2.

A multiplex pharmacogenetics assay using the MinION nanopore sequencing device.

Liau Y, Cree SL, Maggo S, Miller AL, Pearson JF, Gladding PA, Kennedy MA.

Pharmacogenet Genomics. 2019 Nov;29(9):207-215. doi: 10.1097/FPC.0000000000000385.

PMID:
31568131
3.

Nanopore sequencing of the pharmacogene CYP2D6 allows simultaneous haplotyping and detection of duplications.

Liau Y, Maggo S, Miller AL, Pearson JF, Kennedy MA, Cree SL.

Pharmacogenomics. 2019 Sep;20(14):1033-1047. doi: 10.2217/pgs-2019-0080.

PMID:
31559921
4.

PharmVar GeneReview: CYP2D6.

Nofziger C, Turner AJ, Sangkuhl K, Whirl-Carrillo M, Agúndez JAG, Black JL, Dunnenberger HM, Ruano G, Kennedy MA, Phillips MS, Hachad H, Klein TE, Gaedigk A.

Clin Pharmacol Ther. 2019 Sep 22. doi: 10.1002/cpt.1643. [Epub ahead of print] Review.

PMID:
31544239
5.

Metoclopramide-Induced Acute Dystonic Reactions May Be Associated With the CYP2D6 Poor Metabolizer Status and Pregnancy-Related Hormonal Changes.

Chua EW, Harger SP, Kennedy MA.

Front Pharmacol. 2019 Aug 22;10:931. doi: 10.3389/fphar.2019.00931. eCollection 2019.

6.

Adapting and validating informatics competencies for senior nurse leaders in the Canadian context: Results of a Delphi study.

Strudwick G, Nagle LM, Morgan A, Kennedy MA, Currie LM, Lo B, White P.

Int J Med Inform. 2019 Sep;129:211-218. doi: 10.1016/j.ijmedinf.2019.06.012. Epub 2019 Jun 18.

PMID:
31445258
7.

Contrasting signals of cardiovascular health among natriuretic peptides in subjects without heart disease.

Prickett TCR, Spittlehouse JK, Miller AL, Liau Y, Kennedy MA, Cameron VA, Pearson JF, Boden JM, Troughton RW, Espiner EA.

Sci Rep. 2019 Aug 20;9(1):12108. doi: 10.1038/s41598-019-48553-y.

8.

Human gut microbiome changes during a 10 week Randomised Control Trial for micronutrient supplementation in children with attention deficit hyperactivity disorder.

Stevens AJ, Purcell RV, Darling KA, Eggleston MJF, Kennedy MA, Rucklidge JJ.

Sci Rep. 2019 Jul 12;9(1):10128. doi: 10.1038/s41598-019-46146-3.

9.

Solution NMR structure and ligand identification of human Gas7 SH3 domain reveal a typical SH3 fold but a non-canonical ligand-binding mode.

Nie Y, Zhu J, Ramelot TA, Kennedy MA, Liu M, He T, Yang Y.

Biochem Biophys Res Commun. 2019 Sep 3;516(4):1190-1195. doi: 10.1016/j.bbrc.2019.07.004. Epub 2019 Jul 9.

PMID:
31296381
10.

Solution NMR structure of CGL2373, a polyketide cyclase-like protein from Corynebacterium glutamicum.

Cai C, Nie Y, Gong Y, Li S, Ramelot TA, Kennedy MA, Yue X, Zhu J, Liu M, Yang Y.

Proteins. 2019 Jul 11. doi: 10.1002/prot.25771. [Epub ahead of print]

PMID:
31294849
11.

Effectiveness of Ambulatory Telemedicine Care in Older Adults: A Systematic Review.

Batsis JA, DiMilia PR, Seo LM, Fortuna KL, Kennedy MA, Blunt HB, Bagley PJ, Brooks J, Brooks E, Kim SY, Masutani RK, Bruce ML, Bartels SJ.

J Am Geriatr Soc. 2019 Aug;67(8):1737-1749. doi: 10.1111/jgs.15959. Epub 2019 May 8. Review.

PMID:
31066916
12.

Comparing the variants of takotsubo syndrome: an observational study of the ECG and structural changes from a New Zealand tertiary hospital.

Watson GM, Chan CW, Belluscio L, Doudney K, Lacey CJ, Kennedy MA, Bridgman P.

BMJ Open. 2019 May 5;9(5):e025253. doi: 10.1136/bmjopen-2018-025253.

13.

Targeted drug delivery via caveolae-associated protein PV1 improves lung fibrosis.

Marchetti GM, Burwell TJ, Peterson NC, Cann JA, Hanna RN, Li Q, Ongstad EL, Boyd JT, Kennedy MA, Zhao W, Rickert KW, Grimsby JS, Dall'Acqua WF, Wu H, Tsui P, Borrok MJ, Gupta R.

Commun Biol. 2019 Mar 7;2:92. doi: 10.1038/s42003-019-0337-2. eCollection 2019.

14.

RANCM: a new ranking scheme for assigning confidence levels to metabolite assignments in NMR-based metabolomics studies.

Joesten WC, Kennedy MA.

Metabolomics. 2019 Jan 3;15(1):5. doi: 10.1007/s11306-018-1465-2.

PMID:
30830432
15.

Evaluation of the Antibacterial Activity of 75 Mushrooms Collected in the Vicinity of Oxford, Ohio (USA).

Hassan F, Ni S, Becker TL, Kinstedt CM, Abdul-Samad JL, Actis LA, Kennedy MA.

Int J Med Mushrooms. 2019;21(2):131-141. doi: 10.1615/IntJMedMushrooms.2018029710.

PMID:
30806220
16.

Friends, family, and boyfriends: An analysis of relationship pathways into commercial sexual exploitation.

Reed SM, Kennedy MA, Decker MR, Cimino AN.

Child Abuse Negl. 2019 Apr;90:1-12. doi: 10.1016/j.chiabu.2019.01.016. Epub 2019 Jan 30.

PMID:
30716650
17.

A Tie2 kinase mutation causing venous malformations increases phosphorylation rates and enhances cooperativity.

Kennedy MA, Xu Z, Wu Y, Sohl CD.

Biochem Biophys Res Commun. 2019 Feb 19;509(4):898-902. doi: 10.1016/j.bbrc.2019.01.020. Epub 2019 Jan 11.

PMID:
30638931
18.

The Potential for Cancer Immunotherapy in Targeting Surgery-Induced Natural Killer Cell Dysfunction.

Market M, Baxter KE, Angka L, Kennedy MA, Auer RC.

Cancers (Basel). 2018 Dec 20;11(1). pii: E2. doi: 10.3390/cancers11010002. Review.

19.

Gene expression effects of lithium and valproic acid in a serotonergic cell line.

Balasubramanian D, Pearson JF, Kennedy MA.

Physiol Genomics. 2019 Feb 1;51(2):43-50. doi: 10.1152/physiolgenomics.00069.2018. Epub 2018 Dec 21.

PMID:
30576260
20.

Pharmacogenetics of angiotensin-converting enzyme inhibitor-induced angioedema.

Liau Y, Chua I, Kennedy MA, Maggo S.

Clin Exp Allergy. 2019 Feb;49(2):142-154. doi: 10.1111/cea.13326. Epub 2019 Jan 8. Review.

PMID:
30537422
21.

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders.

Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, Degenhardt F, Docherty AR, Edwards AC, Fontanillas P, Foo JC, Fox L, Frank J, Giegling I, Gordon S, Hack LM, Hartmann AM, Hartz SM, Heilmann-Heimbach S, Herms S, Hodgkinson C, Hoffmann P, Jan Hottenga J, Kennedy MA, Alanne-Kinnunen M, Konte B, Lahti J, Lahti-Pulkkinen M, Lai D, Ligthart L, Loukola A, Maher BS, Mbarek H, McIntosh AM, McQueen MB, Meyers JL, Milaneschi Y, Palviainen T, Pearson JF, Peterson RE, Ripatti S, Ryu E, Saccone NL, Salvatore JE, Sanchez-Roige S, Schwandt M, Sherva R, Streit F, Strohmaier J, Thomas N, Wang JC, Webb BT, Wedow R, Wetherill L, Wills AG; 23andMe Research Team, Boardman JD, Chen D, Choi DS, Copeland WE, Culverhouse RC, Dahmen N, Degenhardt L, Domingue BW, Elson SL, Frye MA, Gäbel W, Hayward C, Ising M, Keyes M, Kiefer F, Kramer J, Kuperman S, Lucae S, Lynskey MT, Maier W, Mann K, Männistö S, Müller-Myhsok B, Murray AD, Nurnberger JI, Palotie A, Preuss U, Räikkönen K, Reynolds MD, Ridinger M, Scherbaum N, Schuckit MA, Soyka M, Treutlein J, Witt S, Wodarz N, Zill P, Adkins DE, Boden JM, Boomsma DI, Bierut LJ, Brown SA, Bucholz KK, Cichon S, Costello EJ, de Wit H, Diazgranados N, Dick DM, Eriksson JG, Farrer LA, Foroud TM, Gillespie NA, Goate AM, Goldman D, Grucza RA, Hancock DB, Harris KM, Heath AC, Hesselbrock V, Hewitt JK, Hopfer CJ, Horwood J, Iacono W, Johnson EO, Kaprio JA, Karpyak VM, Kendler KS, Kranzler HR, Krauter K, Lichtenstein P, Lind PA, McGue M, MacKillop J, Madden PAF, Maes HH, Magnusson P, Martin NG, Medland SE, Montgomery GW, Nelson EC, Nöthen MM, Palmer AA, Pedersen NL, Penninx BWJH, Porjesz B, Rice JP, Rietschel M, Riley BP, Rose R, Rujescu D, Shen PH, Silberg J, Stallings MC, Tarter RE, Vanyukov MM, Vrieze S, Wall TL, Whitfield JB, Zhao H, Neale BM, Gelernter J, Edenberg HJ, Agrawal A.

Nat Neurosci. 2018 Dec;21(12):1656-1669. doi: 10.1038/s41593-018-0275-1. Epub 2018 Nov 26.

22.

Solution NMR structure of CHU_1110 from Cytophaga hutchinsonii, an AHSA1 protein potentially involved in metal ion stress response.

Liang C, Zhu J, Ramelot TA, Kennedy MA, Yue X, Li X, Liu M, He T, Yang Y.

Proteins. 2019 Jan;87(1):91-95. doi: 10.1002/prot.25622. Epub 2018 Nov 11.

PMID:
30368907
23.

Bridging the gap between clinicians and fitness professionals: a challenge to implementing exercise as medicine.

Pojednic R, Bantham A, Arnstein F, Kennedy MA, Phillips E.

BMJ Open Sport Exerc Med. 2018 Oct 16;4(1):e000369. doi: 10.1136/bmjsem-2018-000369. eCollection 2018.

24.

Penetrance and expressivity of the R858H CACNA1C variant in a five-generation pedigree segregating an arrhythmogenic channelopathy.

Gardner RJM, Crozier IG, Binfield AL, Love DR, Lehnert K, Gibson K, Lintott CJ, Snell RG, Jacobsen JC, Jones PP, Waddell-Smith KE, Kennedy MA, Skinner JR.

Mol Genet Genomic Med. 2019 Jan;7(1):e00476. doi: 10.1002/mgg3.476. Epub 2018 Oct 21.

25.

The Anorexia Nervosa Genetics Initiative (ANGI): Overview and methods.

Thornton LM, Munn-Chernoff MA, Baker JH, Juréus A, Parker R, Henders AK, Larsen JT, Petersen L, Watson HJ, Yilmaz Z, Kirk KM, Gordon S, Leppä VM, Martin FC, Whiteman DC, Olsen CM, Werge TM, Pedersen NL, Kaye W, Bergen AW, Halmi KA, Strober M, Kaplan AS, Woodside DB, Mitchell J, Johnson CL, Brandt H, Crawford S, Horwood LJ, Boden JM, Pearson JF, Duncan LE, Grove J, Mattheisen M, Jordan J, Kennedy MA, Birgegård A, Lichtenstein P, Norring C, Wade TD, Montgomery GW, Martin NG, Landén M, Mortensen PB, Sullivan PF, Bulik CM.

Contemp Clin Trials. 2018 Nov;74:61-69. doi: 10.1016/j.cct.2018.09.015. Epub 2018 Oct 1.

26.

Can we predict treatment response in children with ADHD to a vitamin-mineral supplement? An investigation into pre-treatment nutrient serum levels, MTHFR status, clinical correlates and demographic variables.

Rucklidge JJ, Eggleston MJF, Darling KA, Stevens AJ, Kennedy MA, Frampton CM.

Prog Neuropsychopharmacol Biol Psychiatry. 2019 Mar 8;89:181-192. doi: 10.1016/j.pnpbp.2018.09.007. Epub 2018 Sep 12.

PMID:
30217770
27.

Natural Killer Cell IFNγ Secretion is Profoundly Suppressed Following Colorectal Cancer Surgery.

Angka L, Martel AB, Kilgour M, Jeong A, Sadiq M, de Souza CT, Baker L, Kennedy MA, Kekre N, Auer RC.

Ann Surg Oncol. 2018 Nov;25(12):3747-3754. doi: 10.1245/s10434-018-6691-3. Epub 2018 Sep 5.

PMID:
30187278
28.

Methylomic changes in response to micronutrient supplementation and MTHFR genotype.

Stevens AJ, Rucklidge JJ, Darling KA, Eggleston MJ, Pearson JF, Kennedy MA.

Epigenomics. 2018 Sep;10(9):1201-1214. doi: 10.2217/epi-2018-0029. Epub 2018 Sep 5.

29.

Solution structure of SHIP2 SH2 domain and its interaction with a phosphotyrosine peptide from c-MET.

Wang Z, Nie Y, Zhang K, Xu H, Ramelot TA, Kennedy MA, Liu M, Zhu J, Yang Y.

Arch Biochem Biophys. 2018 Oct 15;656:31-37. doi: 10.1016/j.abb.2018.08.012. Epub 2018 Aug 27.

30.

A genome project for Māori and Pasifika: charting a path to equity in genomic medicine for Aotearoa.

Kennedy MA.

N Z Med J. 2018 Aug 17;131(1480):8-10. No abstract available.

PMID:
30116058
31.

Testicular Cancer in New Zealand (TCNZ) study: protocol for a national case-control study.

Gurney JK, Stanley J, McGlynn K, Richiardi L, Shaw C, Edwards R, Merriman TR, Robson B, Koea J, McLeod M, Kennedy MA, Sarfati D.

BMJ Open. 2018 Aug 5;8(8):e025212. doi: 10.1136/bmjopen-2018-025212.

32.

NMR-based metabolic profiling of urine, serum, fecal, and pancreatic tissue samples from the Ptf1a-Cre; LSL-KrasG12D transgenic mouse model of pancreatic cancer.

Schmahl MJ, Regan DP, Rivers AC, Joesten WC, Kennedy MA.

PLoS One. 2018 Jul 17;13(7):e0200658. doi: 10.1371/journal.pone.0200658. eCollection 2018.

33.

NMR-based urine metabolic profiling and immunohistochemistry analysis of nephron changes in a mouse model of hypoxia-induced acute kidney injury.

Chihanga T, Ruby HN, Ma Q, Bashir S, Devarajan P, Kennedy MA.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F1159-F1173. doi: 10.1152/ajprenal.00500.2017. Epub 2018 Jul 11.

34.

Phosphodiesterase-5 inhibition reduces postoperative metastatic disease by targeting surgery-induced myeloid derived suppressor cell-dependent inhibition of Natural Killer cell cytotoxicity.

Tai LH, Alkayyal AA, Leslie AL, Sahi S, Bennett S, Tanese de Souza C, Baxter K, Angka L, Xu R, Kennedy MA, Auer RC.

Oncoimmunology. 2018 Mar 1;7(6):e1431082. doi: 10.1080/2162402X.2018.1431082. eCollection 2018.

35.

Nonsynonymous Polymorphism in Guanine Monophosphate Synthetase Is a Risk Factor for Unfavorable Thiopurine Metabolite Ratios in Patients With Inflammatory Bowel Disease.

Roberts RL, Wallace MC, Seinen ML, van Bodegraven AA, Krishnaprasad K, Jones GT, van Rij AM, Baird A, Lawrance IC, Prosser R, Bampton P, Grafton R, Simms LA, Studd C, Bell SJ, Kennedy MA, Halliwell J, Gearry RB, Radford-Smith G, Andrews JM, McHugh PC, Barclay ML.

Inflamm Bowel Dis. 2018 Nov 29;24(12):2606-2612. doi: 10.1093/ibd/izy163.

PMID:
29788244
36.

Copy number variants implicate cardiac function and development pathways in earthquake-induced stress cardiomyopathy.

Lacey CJ, Doudney K, Bridgman PG, George PM, Mulder RT, Zarifeh JJ, Kimber B, Cadzow MJ, Black MA, Merriman TR, Lehnert K, Bickley VM, Pearson JF, Cameron VA, Kennedy MA.

Sci Rep. 2018 May 15;8(1):7548. doi: 10.1038/s41598-018-25827-5.

37.

Multiplexed Nanopore Sequencing of HLA-B Locus in Māori and Pacific Island Samples.

Ton KNT, Cree SL, Gronert-Sum SJ, Merriman TR, Stamp LK, Kennedy MA.

Front Genet. 2018 Apr 30;9:152. doi: 10.3389/fgene.2018.00152. eCollection 2018.

38.

Inter-individual variation in imatinib disposition: any role for prevalent variants of CYP1A2, CYP2C8, CYP2C9, and CYP3A5 in Nigerian CML patients?

Adehin A, Adeagbo BA, Kennedy MA, Bolaji OO, Olugbade TA, Bolarinwa RA, Durosinmi MA.

Leuk Lymphoma. 2019 Jan;60(1):216-221. doi: 10.1080/10428194.2018.1466291. Epub 2018 May 9.

PMID:
29741432
39.

Correction to: Sepsis increases perioperative metastases in a murine model.

Tai LH, Ananth AA, Seth R, Alkayyal A, Zhang J, de Souza CT, Staibano P, Kennedy MA, Auer RC.

BMC Cancer. 2018 Apr 17;18(1):437. doi: 10.1186/s12885-018-4248-2.

40.

Sepsis increases perioperative metastases in a murine model.

Tai LH, Ananth AA, Seth R, Alkayyal A, Zhang J, de Souza CT, Staibano P, Kennedy MA, Auer RC.

BMC Cancer. 2018 Mar 12;18(1):277. doi: 10.1186/s12885-018-4173-4. Erratum in: BMC Cancer. 2018 Apr 17;18(1):437.

41.

Adenovirus-Mediated Delivery of Decoy Hyper Binding Sites Targeting Oncogenic HMGA1 Reduces Pancreatic and Liver Cancer Cell Viability.

Hassan F, Ni S, Arnett TC, McKell MC, Kennedy MA.

Mol Ther Oncolytics. 2018 Jan 31;8:52-61. doi: 10.1016/j.omto.2018.01.002. eCollection 2018 Mar 30.

42.
43.

Influence of media selection on NMR based metabolic profiling of human cell lines.

Chihanga T, Hausmann SM, Ni S, Kennedy MA.

Metabolomics. 2018 Jan 31;14(3):28. doi: 10.1007/s11306-018-1323-2.

PMID:
30830358
44.

Structural insights into the impact of two holoprosencephaly-related mutations on human TGIF1 homeodomain.

Zhu J, Li S, Ramelot TA, Kennedy MA, Liu M, Yang Y.

Biochem Biophys Res Commun. 2018 Feb 5;496(2):575-581. doi: 10.1016/j.bbrc.2018.01.099.

PMID:
29355528
45.

Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras.

Xu S, Long BN, Boris GH, Chen A, Ni S, Kennedy MA.

Acta Crystallogr D Struct Biol. 2017 Dec 1;73(Pt 12):970-984. doi: 10.1107/S2059798317015418. Epub 2017 Nov 10.

PMID:
29199977
46.

A New Zealand platform to enable genetic investigation of adverse drug reactions.

Maggo SD, Chua EW, Chin P, Cree S, Pearson J, Doogue M, Kennedy MA.

N Z Med J. 2017 Dec 1;130(1466):62-69.

PMID:
29197902
47.

Nanopore sequencing of full-length BRCA1 mRNA transcripts reveals co-occurrence of known exon skipping events.

de Jong LC, Cree S, Lattimore V, Wiggins GAR, Spurdle AB; kConFab Investigators, Miller A, Kennedy MA, Walker LC.

Breast Cancer Res. 2017 Nov 28;19(1):127. doi: 10.1186/s13058-017-0919-1.

48.

Structural basis of glycan specificity of P[19] VP8*: Implications for rotavirus zoonosis and evolution.

Liu Y, Xu S, Woodruff AL, Xia M, Tan M, Kennedy MA, Jiang X.

PLoS Pathog. 2017 Nov 14;13(11):e1006707. doi: 10.1371/journal.ppat.1006707. eCollection 2017 Nov.

49.
50.

NMR spectroscopy and electron microscopy identification of metabolic and ultrastructural changes to the kidney following ischemia-reperfusion injury.

Chihanga T, Ma Q, Nicholson JD, Ruby HN, Edelmann RE, Devarajan P, Kennedy MA.

Am J Physiol Renal Physiol. 2018 Feb 1;314(2):F154-F166. doi: 10.1152/ajprenal.00363.2017. Epub 2017 Oct 4.

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