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Visible light photoswitching by azobenzazoles.

Kennedy ADW, Sandler I, Andreasson J, Ho J, Beves JE.

Chemistry. 2019 Nov 14. doi: 10.1002/chem.201904309. [Epub ahead of print]


2-Pyrrolidinone and Succinimide as Clinical Screening Biomarkers for GABA-Transaminase Deficiency: Anti-seizure Medications Impact Accurate Diagnosis.

Kennedy AD, Pappan KL, Donti T, Delgado MR, Shinawi M, Pearson TS, Lalani SR, Craigen WE, Sutton VR, Evans AM, Sun Q, Emrick LT, Elsea SH.

Front Neurosci. 2019 May 8;13:394. doi: 10.3389/fnins.2019.00394. eCollection 2019.


Diastereoselective Control of Tetraphenylethene Reactivity by Metal Template Self-Assembly.

Kennedy ADW, de Haas N, Iranmanesh H, Luis ET, Shen C, Wang P, Price JR, Donald WA, Andréasson J, Huang F, Beves JE.

Chemistry. 2019 Apr 17;25(22):5708-5718. doi: 10.1002/chem.201806259. Epub 2019 Mar 27.


Untargeted metabolomic profiling reveals multiple pathway perturbations and new clinical biomarkers in urea cycle disorders.

Burrage LC, Thistlethwaite L, Stroup BM, Sun Q, Miller MJ, Nagamani SCS, Craigen W, Scaglia F, Sutton VR, Graham B, Kennedy AD; Members of the UCDC,, Milosavljevic A, Lee BH, Elsea SH.

Genet Med. 2019 Sep;21(9):1977-1986. doi: 10.1038/s41436-019-0442-0. Epub 2019 Jan 23.


Untargeted metabolomics identifies unique though benign biochemical changes in patients with pathogenic variants in UROC1.

Glinton KE, Levy HL, Kennedy AD, Pappan KL, Elsea SH.

Mol Genet Metab Rep. 2018 Dec 29;18:14-18. doi: 10.1016/j.ymgmr.2018.12.005. eCollection 2019 Mar.


Structure-function relationships of donor-acceptor Stenhouse adduct photochromic switches.

Mallo N, Foley ED, Iranmanesh H, Kennedy ADW, Luis ET, Ho J, Harper JB, Beves JE.

Chem Sci. 2018 Sep 12;9(43):8242-8252. doi: 10.1039/c8sc03218a. eCollection 2018 Nov 21.


Metabolomics in the clinic: A review of the shared and unique features of untargeted metabolomics for clinical research and clinical testing.

Kennedy AD, Wittmann BM, Evans AM, Miller LAD, Toal DR, Lonergan S, Elsea SH, Pappan KL.

J Mass Spectrom. 2018 Nov;53(11):1143-1154. doi: 10.1002/jms.4292. Review.


A metabolomic map of Zellweger spectrum disorders reveals novel disease biomarkers.

Wangler MF, Hubert L, Donti TR, Ventura MJ, Miller MJ, Braverman N, Gawron K, Bose M, Moser AB, Jones RO, Rizzo WB, Sutton VR, Sun Q, Kennedy AD, Elsea SH.

Genet Med. 2018 Oct;20(10):1274-1283. doi: 10.1038/gim.2017.262. Epub 2018 Feb 8.


Cognitive enhancement in old dogs from dietary supplementation with a nutrient blend containing arginine, antioxidants, B vitamins and fish oil.

Pan Y, Kennedy AD, Jönsson TJ, Milgram NW.

Br J Nutr. 2018 Feb;119(3):349-358. doi: 10.1017/S0007114517003464. Epub 2018 Jan 10.


Disturbed phospholipid metabolism in serine biosynthesis defects revealed by metabolomic profiling.

Glinton KE, Benke PJ, Lines MA, Geraghty MT, Chakraborty P, Al-Dirbashi OY, Jiang Y, Kennedy AD, Grotewiel MS, Sutton VR, Elsea SH, El-Hattab AW.

Mol Genet Metab. 2018 Mar;123(3):309-316. doi: 10.1016/j.ymgme.2017.12.009. Epub 2017 Dec 12.


Metabolic Differences between Dogs of Different Body Sizes.

Middleton RP, Lacroix S, Scott-Boyer MP, Dordevic N, Kennedy AD, Slusky AR, Carayol J, Petzinger-Germain C, Beloshapka A, Kaput J.

J Nutr Metab. 2017;2017:4535710. doi: 10.1155/2017/4535710. Epub 2017 Oct 26.


Biochemical phenotyping unravels novel metabolic abnormalities and potential biomarkers associated with treatment of GLUT1 deficiency with ketogenic diet.

Cappuccio G, Pinelli M, Alagia M, Donti T, Day-Salvatore DL, Veggiotti P, De Giorgis V, Lunghi S, Vari MS, Striano P, Brunetti-Pierri N, Kennedy AD, Elsea SH.

PLoS One. 2017 Sep 29;12(9):e0184022. doi: 10.1371/journal.pone.0184022. eCollection 2017.


Clinical Metabolomics to Segregate Aromatic Amino Acid Decarboxylase Deficiency From Drug-Induced Metabolite Elevations.

Pappan KL, Kennedy AD, Magoulas PL, Hanchard NA, Sun Q, Elsea SH.

Pediatr Neurol. 2017 Oct;75:66-72. doi: 10.1016/j.pediatrneurol.2017.06.014. Epub 2017 Jun 29.


Analyses of SLC13A5-epilepsy patients reveal perturbations of TCA cycle.

Bainbridge MN, Cooney E, Miller M, Kennedy AD, Wulff JE, Donti T, Jhangiani SN, Gibbs RA, Elsea SH, Porter BE, Graham BH.

Mol Genet Metab. 2017 Aug;121(4):314-319. doi: 10.1016/j.ymgme.2017.06.009. Epub 2017 Jun 24.


Subversion of allocation concealment in a randomised controlled trial: a historical case study.

Kennedy ADM, Torgerson DJ, Campbell MK, Grant AM.

Trials. 2017 May 2;18(1):204. doi: 10.1186/s13063-017-1946-z.


Elucidation of the complex metabolic profile of cerebrospinal fluid using an untargeted biochemical profiling assay.

Kennedy AD, Pappan KL, Donti TR, Evans AM, Wulff JE, Miller LAD, Reid Sutton V, Sun Q, Miller MJ, Elsea SH.

Mol Genet Metab. 2017 Jun;121(2):83-90. doi: 10.1016/j.ymgme.2017.04.005. Epub 2017 Apr 9.


Analytes related to erythrocyte metabolism are reliable biomarkers for preanalytical error due to delayed plasma processing in metabolomics studies.

Jain M, Kennedy AD, Elsea SH, Miller MJ.

Clin Chim Acta. 2017 Mar;466:105-111. doi: 10.1016/j.cca.2017.01.005. Epub 2017 Jan 6.


Excited States of Triphenylamine-Substituted 2-Pyridyl-1,2,3-triazole Complexes.

Huff GS, Lo WK, Horvath R, Turner JO, Sun XZ, Weal GR, Davidson HJ, Kennedy AD, McAdam CJ, Crowley JD, George MW, Gordon KC.

Inorg Chem. 2016 Dec 5;55(23):12238-12253. Epub 2016 Nov 14.


Metabolomic Profiling of Human Urine as a Screen for Multiple Inborn Errors of Metabolism.

Kennedy AD, Miller MJ, Beebe K, Wulff JE, Evans AM, Miller LA, Sutton VR, Sun Q, Elsea SH.

Genet Test Mol Biomarkers. 2016 Sep;20(9):485-95. doi: 10.1089/gtmb.2015.0291. Epub 2016 Jul 22.


Cloud fraction at the ARM SGP site: reducing uncertainty with self-organizing maps.

Kennedy AD, Dong X, Xi B.

Theor Appl Climatol. 2016;124:43-54. Epub 2015 Feb 15.


Erratum to: Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism.

Miller MJ, Kennedy AD, Eckhart AD, Burrage LC, Wulff JE, Miller LAD, Milburn MV, Ryals JA, Beaudet AL, Sun Q, Sutton VR, Elsea SH.

J Inherit Metab Dis. 2016 Sep;39(5):757. doi: 10.1007/s10545-016-9944-y. No abstract available.


Chronic Oral L-Carnitine Supplementation Drives Marked Plasma TMAO Elevations in Patients with Organic Acidemias Despite Dietary Meat Restrictions.

Miller MJ, Bostwick BL, Kennedy AD, Donti TR, Sun Q, Sutton VR, Elsea SH.

JIMD Rep. 2016;30:39-44. Epub 2016 Mar 3.


Sharpening Precision Medicine by a Thorough Interrogation of Metabolic Individuality.

Beebe K, Kennedy AD.

Comput Struct Biotechnol J. 2016 Jan 21;14:97-105. doi: 10.1016/j.csbj.2016.01.001. eCollection 2016. Review.


Elevations of C14:1 and C14:2 Plasma Acylcarnitines in Fasted Children: A Diagnostic Dilemma.

Burrage LC, Miller MJ, Wong LJ, Kennedy AD, Sutton VR, Sun Q, Elsea SH, Graham BH.

J Pediatr. 2016 Feb;169:208-13.e2. doi: 10.1016/j.jpeds.2015.10.045. Epub 2015 Nov 18.


Exploratory Metabolomic Analyses Reveal Compounds Correlated with Lutein Concentration in Frontal Cortex, Hippocampus, and Occipital Cortex of Human Infant Brain.

Lieblein-Boff JC, Johnson EJ, Kennedy AD, Lai CS, Kuchan MJ.

PLoS One. 2015 Aug 28;10(8):e0136904. doi: 10.1371/journal.pone.0136904. eCollection 2015.


Veterinary Medicine and Multi-Omics Research for Future Nutrition Targets: Metabolomics and Transcriptomics of the Common Degenerative Mitral Valve Disease in Dogs.

Li Q, Freeman LM, Rush JE, Huggins GS, Kennedy AD, Labuda JA, Laflamme DP, Hannah SS.

OMICS. 2015 Aug;19(8):461-70. doi: 10.1089/omi.2015.0057. Epub 2015 Jul 8.


Untargeted metabolomic analysis for the clinical screening of inborn errors of metabolism.

Miller MJ, Kennedy AD, Eckhart AD, Burrage LC, Wulff JE, Miller LA, Milburn MV, Ryals JA, Beaudet AL, Sun Q, Sutton VR, Elsea SH.

J Inherit Metab Dis. 2015 Nov;38(6):1029-39. doi: 10.1007/s10545-015-9843-7. Epub 2015 Apr 15. Erratum in: J Inherit Metab Dis. 2016 Sep;39(5):757.


Comparison of inverse and regular 2-pyridyl-1,2,3-triazole "click" complexes: structures, stability, electrochemical, and photophysical properties.

Lo WK, Huff GS, Cubanski JR, Kennedy AD, McAdam CJ, McMorran DA, Gordon KC, Crowley JD.

Inorg Chem. 2015 Feb 16;54(4):1572-87. doi: 10.1021/ic502557w. Epub 2015 Jan 23.


Global metabolomic analysis of human saliva and plasma from healthy and diabetic subjects, with and without periodontal disease.

Barnes VM, Kennedy AD, Panagakos F, Devizio W, Trivedi HM, Jönsson T, Guo L, Cervi S, Scannapieco FA.

PLoS One. 2014 Aug 18;9(8):e105181. doi: 10.1371/journal.pone.0105181. eCollection 2014. Erratum in: PLoS One. 2014;9(11):e114091.


Direct evidence for the presence of human milk oligosaccharides in the circulation of breastfed infants.

Goehring KC, Kennedy AD, Prieto PA, Buck RH.

PLoS One. 2014 Jul 7;9(7):e101692. doi: 10.1371/journal.pone.0101692. eCollection 2014.


Phagocytosis and killing of Staphylococcus aureus by human neutrophils.

Lu T, Porter AR, Kennedy AD, Kobayashi SD, DeLeo FR.

J Innate Immun. 2014;6(5):639-49. doi: 10.1159/000360478. Epub 2014 Apr 5.


Metabolomic profiling reveals severe skeletal muscle group-specific perturbations of metabolism in aged FBN rats.

Garvey SM, Dugle JE, Kennedy AD, McDunn JE, Kline W, Guo L, Guttridge DC, Pereira SL, Edens NK.

Biogerontology. 2014 Jun;15(3):217-32. doi: 10.1007/s10522-014-9492-5. Epub 2014 Mar 21.


A strategically designed small molecule attacks alpha-ketoglutarate dehydrogenase in tumor cells through a redox process.

Stuart SD, Schauble A, Gupta S, Kennedy AD, Keppler BR, Bingham PM, Zachar Z.

Cancer Metab. 2014 Mar 10;2(1):4. doi: 10.1186/2049-3002-2-4.


The Mycobacterium tuberculosis regulatory network and hypoxia.

Galagan JE, Minch K, Peterson M, Lyubetskaya A, Azizi E, Sweet L, Gomes A, Rustad T, Dolganov G, Glotova I, Abeel T, Mahwinney C, Kennedy AD, Allard R, Brabant W, Krueger A, Jaini S, Honda B, Yu WH, Hickey MJ, Zucker J, Garay C, Weiner B, Sisk P, Stolte C, Winkler JK, Van de Peer Y, Iazzetti P, Camacho D, Dreyfuss J, Liu Y, Dorhoi A, Mollenkopf HJ, Drogaris P, Lamontagne J, Zhou Y, Piquenot J, Park ST, Raman S, Kaufmann SH, Mohney RP, Chelsky D, Moody DB, Sherman DR, Schoolnik GK.

Nature. 2013 Jul 11;499(7457):178-83. doi: 10.1038/nature12337. Epub 2013 Jul 3.


Toward an understanding of the evolution of Staphylococcus aureus strain USA300 during colonization in community households.

Uhlemann AC, Kennedy AD, Martens C, Porcella SF, Deleo FR, Lowy FD.

Genome Biol Evol. 2012;4(12):1275-85. doi: 10.1093/gbe/evs094.


Using a mobile phone application in youth mental health - an evaluation study.

Reid SC, Kauer SD, Khor AS, Hearps SJ, Sanci LA, Kennedy AD, Patton GC.

Aust Fam Physician. 2012 Sep;41(9):711-4.


Identification of a highly transmissible animal-independent Staphylococcus aureus ST398 clone with distinct genomic and cell adhesion properties.

Uhlemann AC, Porcella SF, Trivedi S, Sullivan SB, Hafer C, Kennedy AD, Barbian KD, McCarthy AJ, Street C, Hirschberg DL, Lipkin WI, Lindsay JA, DeLeo FR, Lowy FD.

MBio. 2012 Feb 28;3(2). pii: e00027-12. doi: 10.1128/mBio.00027-12. Print 2012.


Molecular differentiation of historic phage-type 80/81 and contemporary epidemic Staphylococcus aureus.

DeLeo FR, Kennedy AD, Chen L, Bubeck Wardenburg J, Kobayashi SD, Mathema B, Braughton KR, Whitney AR, Villaruz AE, Martens CA, Porcella SF, McGavin MJ, Otto M, Musser JM, Kreiswirth BN.

Proc Natl Acad Sci U S A. 2011 Nov 1;108(44):18091-6. doi: 10.1073/pnas.1111084108. Epub 2011 Oct 24.


Effect of warfarin on menstruation and menstrual management of the adolescent on warfarin.

Peake LJ, Grover SR, Monagle PT, Kennedy AD.

J Paediatr Child Health. 2011 Dec;47(12):893-7. doi: 10.1111/j.1440-1754.2011.02101.x. Epub 2011 Jun 9.


Global changes in Staphylococcus aureus gene expression in human blood.

Malachowa N, Whitney AR, Kobayashi SD, Sturdevant DE, Kennedy AD, Braughton KR, Shabb DW, Diep BA, Chambers HF, Otto M, DeLeo FR.

PLoS One. 2011 Apr 15;6(4):e18617. doi: 10.1371/journal.pone.0018617.


Complete nucleotide sequence analysis of plasmids in strains of Staphylococcus aureus clone USA300 reveals a high level of identity among isolates with closely related core genome sequences.

Kennedy AD, Porcella SF, Martens C, Whitney AR, Braughton KR, Chen L, Craig CT, Tenover FC, Kreiswirth BN, Musser JM, DeLeo FR.

J Clin Microbiol. 2010 Dec;48(12):4504-11. doi: 10.1128/JCM.01050-10. Epub 2010 Oct 13.


Targeting of alpha-hemolysin by active or passive immunization decreases severity of USA300 skin infection in a mouse model.

Kennedy AD, Bubeck Wardenburg J, Gardner DJ, Long D, Whitney AR, Braughton KR, Schneewind O, DeLeo FR.

J Infect Dis. 2010 Oct 1;202(7):1050-8. doi: 10.1086/656043.


Rapid neutrophil destruction following phagocytosis of Staphylococcus aureus.

Kobayashi SD, Braughton KR, Palazzolo-Ballance AM, Kennedy AD, Sampaio E, Kristosturyan E, Whitney AR, Sturdevant DE, Dorward DW, Holland SM, Kreiswirth BN, Musser JM, DeLeo FR.

J Innate Immun. 2010;2(6):560-75. doi: 10.1159/000317134. Epub 2010 Jun 26.


Host-microbe interaction systems biology: lifecycle transcriptomics and comparative genomics.

Sturdevant DE, Virtaneva K, Martens C, Bozinov D, Ogundare O, Castro N, Kanakabandi K, Beare PA, Omsland A, Carlson JH, Kennedy AD, Heinzen RA, Celli J, Greenberg DE, DeLeo FR, Porcella SF.

Future Microbiol. 2010 Feb;5(2):205-19. doi: 10.2217/fmb.09.125. Review. Erratum in: Future Microbiol. 2010 Mar;5(3):526. Ohmsland, Anders [corrected to Omsland, Anders].


Strategies of survival and resource exploitation in the Antarctic fellfield ecosystem.

Block W, Lewis Smith RI, Kennedy AD.

Biol Rev Camb Philos Soc. 2009 Aug;84(3):449-84. doi: 10.1111/j.1469-185X.2009.00084.x. Review.


Neutrophil apoptosis and the resolution of infection.

Kennedy AD, DeLeo FR.

Immunol Res. 2009;43(1-3):25-61. doi: 10.1007/s12026-008-8049-6. Review.


PI3K and NADPH oxidase: a class act.

Kennedy AD, DeLeo FR.

Blood. 2008 Dec 15;112(13):4788-9. doi: 10.1182/blood-2008-09-179135. No abstract available.


Effects of feed delivery time on feed intake, milk production, and blood metabolites of dairy cows.

Nikkhah A, Furedi CJ, Kennedy AD, Crow GH, Plaizier JC.

J Dairy Sci. 2008 Nov;91(11):4249-60. doi: 10.3168/jds.2008-1075.


Epidemic community-associated methicillin-resistant Staphylococcus aureus: recent clonal expansion and diversification.

Kennedy AD, Otto M, Braughton KR, Whitney AR, Chen L, Mathema B, Mediavilla JR, Byrne KA, Parkins LD, Tenover FC, Kreiswirth BN, Musser JM, DeLeo FR.

Proc Natl Acad Sci U S A. 2008 Jan 29;105(4):1327-32. doi: 10.1073/pnas.0710217105. Epub 2008 Jan 23.


Identification of novel cytolytic peptides as key virulence determinants for community-associated MRSA.

Wang R, Braughton KR, Kretschmer D, Bach TH, Queck SY, Li M, Kennedy AD, Dorward DW, Klebanoff SJ, Peschel A, DeLeo FR, Otto M.

Nat Med. 2007 Dec;13(12):1510-4. Epub 2007 Nov 11.


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