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Items: 16


γ-Tocotrienol and α-Tocopherol Ether Acetate Enhance Docetaxel Activity in Drug-Resistant Prostate Cancer Cells.

Asay S, Graham A, Hollingsworth S, Barnes B, Oblad RV, Michaelis DJ, Kenealey JD.

Molecules. 2020 Jan 18;25(2). pii: E398. doi: 10.3390/molecules25020398.


Resveratrol derivatives increase cytosolic calcium by inhibiting plasma membrane ATPase and inducing calcium release from the endoplasmic reticulum in prostate cancer cells.

Peterson JA, Crowther CM, Andrus MB, Kenealey JD.

Biochem Biophys Rep. 2019 Jul 20;19:100667. doi: 10.1016/j.bbrep.2019.100667. eCollection 2019 Sep.


Measuring Enzymatic Stability by Isothermal Titration Calorimetry.

Chan WKD, Mason M, Hansen LD, Kenealey JD.

J Vis Exp. 2019 Mar 26;(145). doi: 10.3791/59302.


Application of Mixture Design Response Surface Methodology for Combination Chemotherapy in PC-3 Human Prostate Cancer Cells.

Oblad R, Doughty H, Lawson J, Christensen M, Kenealey J.

Mol Pharmacol. 2018 Aug;94(2):907-916. doi: 10.1124/mol.117.111450. Epub 2018 Jun 8.


Calorimetric Methods for Measuring Stability and Reusability of Membrane Immobilized Enzymes.

Mason M, Scampicchio M, Quinn CF, Transtrum MK, Baker N, Hansen LD, Kenealey JD.

J Food Sci. 2018 Feb;83(2):326-331. doi: 10.1111/1750-3841.14023. Epub 2017 Dec 26.


The Effects of 4'-Esterified Resveratrol Derivatives on Calcium Dynamics in Breast Cancer Cells.

Peterson JA, Doughty HP, Eells AJ, Johnson TA, Hastings JP, Crowther CM, Andrus MB, Kenealey JD.

Molecules. 2017 Nov 14;22(11). pii: E1968. doi: 10.3390/molecules22111968.


Avenanthramide-C reduces the viability of MDA-MB-231 breast cancer cells through an apoptotic mechanism.

Hastings J, Kenealey J.

Cancer Cell Int. 2017 Oct 18;17:93. doi: 10.1186/s12935-017-0464-0. eCollection 2017.


Resveratrol inhibits plasma membrane Ca2+-ATPase inducing an increase in cytoplasmic calcium.

Peterson JA, Oblad RV, Mecham JC, Kenealey JD.

Biochem Biophys Rep. 2016 Jun 30;7:253-258. doi: 10.1016/j.bbrep.2016.06.019. eCollection 2016 Sep.


Natural products induce a G protein-mediated calcium pathway activating p53 in cancer cells.

van Ginkel PR, Yan MB, Bhattacharya S, Polans AS, Kenealey JD.

Toxicol Appl Pharmacol. 2015 Nov 1;288(3):453-62. doi: 10.1016/j.taap.2015.08.016. Epub 2015 Sep 1.


Small Retinoprotective Peptides Reveal a Receptor-binding Region on Pigment Epithelium-derived Factor.

Kenealey J, Subramanian P, Comitato A, Bullock J, Keehan L, Polato F, Hoover D, Marigo V, Becerra SP.

J Biol Chem. 2015 Oct 16;290(42):25241-53. doi: 10.1074/jbc.M115.645846. Epub 2015 Aug 24.


The sustained delivery of resveratrol or a defined grape powder inhibits new blood vessel formation in a mouse model of choroidal neovascularization.

Kanavi MR, Darjatmoko S, Wang S, Azari AA, Farnoodian M, Kenealey JD, van Ginkel PR, Albert DM, Sheibani N, Polans AS.

Molecules. 2014 Oct 30;19(11):17578-603. doi: 10.3390/molecules191117578.


Pigment epithelium-derived factor (PEDF) prevents retinal cell death via PEDF Receptor (PEDF-R): identification of a functional ligand binding site.

Subramanian P, Locatelli-Hoops S, Kenealey J, DesJardin J, Notari L, Becerra SP.

J Biol Chem. 2013 Aug 16;288(33):23928-42. doi: 10.1074/jbc.M113.487884. Epub 2013 Jul 1.


Resveratrol metabolites do not elicit early pro-apoptotic mechanisms in neuroblastoma cells.

Kenealey JD, Subramanian L, Van Ginkel PR, Darjatmoko S, Lindstrom MJ, Somoza V, Ghosh SK, Song Z, Hsung RP, Kwon GS, Eliceiri KW, Albert DM, Polans AS.

J Agric Food Chem. 2011 May 11;59(9):4979-86. doi: 10.1021/jf104901g. Epub 2011 Apr 12.


Non-reductive iron release from horse spleen ferritin using desferoxamine chelation.

Johnson J, Kenealey J, Hilton RJ, Brosnahan D, Watt RK, Watt GD.

J Inorg Biochem. 2011 Feb;105(2):202-7. doi: 10.1016/j.jinorgbio.2010.11.002. Epub 2010 Nov 13.


Resveratrol: challenges in translation to the clinic--a critical discussion.

Subramanian L, Youssef S, Bhattacharya S, Kenealey J, Polans AS, van Ginkel PR.

Clin Cancer Res. 2010 Dec 15;16(24):5942-8. doi: 10.1158/1078-0432.CCR-10-1486. Epub 2010 Nov 2. Review.


Evidence for a synergistic salt-protein interaction -- complex patterns of activation vs. inhibition of nitrogenase by salt.

Wilson PE, Nyborg AC, Kenealey J, Lowery TJ, Crawford K, King CR, Engan AJ, Johnson JL, Watt GD.

Biophys Chem. 2006 Aug 1;122(3):184-94. Epub 2006 Apr 17.


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