Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 325

1.

Identification and biochemical analyses of selective CB2 agonists.

Scott CE, Tang Y, Alt A, Burford NT, Gerritz SW, Ogawa LM, Zhang L, Kendall DA.

Eur J Pharmacol. 2019 Jul 5;854:1-8. doi: 10.1016/j.ejphar.2019.03.054. Epub 2019 Apr 3.

PMID:
30951717
2.

Exploring 6-Azaindole and 7-Azaindole Rings for Developing Cannabinoid Receptor 1 Allosteric Modulators.

Immadi SS, Dopart R, Wu Z, Fu B, Kendall DA, Lu D.

Cannabis Cannabinoid Res. 2018 Dec 10;3(1):252-258. doi: 10.1089/can.2018.0046. eCollection 2018.

3.

Translational potential of allosteric modulators targeting the cannabinoid CB1 receptor.

Lu D, Immadi SS, Wu Z, Kendall DA.

Acta Pharmacol Sin. 2019 Mar;40(3):324-335. doi: 10.1038/s41401-018-0164-x. Epub 2018 Oct 17. Review.

PMID:
30333554
4.

Pyrimidinyl Biphenylureas Act as Allosteric Modulators to Activate Cannabinoid Receptor 1 and Initiate β-Arrestin-Dependent Responses.

Jagla CAD, Scott CE, Tang Y, Qiao C, Mateo-Semidey GE, Yudowski GA, Lu D, Kendall DA.

Mol Pharmacol. 2019 Jan;95(1):1-10. doi: 10.1124/mol.118.112854. Epub 2018 Oct 15.

PMID:
30322873
5.

Allosteric modulators of cannabinoid receptor 1: developing compounds for improved specificity.

Dopart R, Lu D, Lichtman AH, Kendall DA.

Drug Metab Rev. 2018 Feb;50(1):3-13. doi: 10.1080/03602532.2018.1428342. Epub 2018 Jan 21. Review.

6.

Discovery of Selective Cannabinoid CB2 Receptor Agonists by High-Throughput Screening.

Ogawa LM, Burford NT, Liao YH, Scott CE, Hine AM, Dowling C, Chin J, Power M, Hunnicutt EJ Jr, Emerick VL, Banks M, Zhang L, Gerritz SW, Alt A, Kendall DA.

SLAS Discov. 2018 Apr;23(4):375-383. doi: 10.1177/2472555217748403. Epub 2017 Dec 19.

7.

Generation and phenotypic characterisation of a cytochrome P450 4x1 knockout mouse.

Kharkwal H, Batool F, Koentgen F, Bell DR, Kendall DA, Ebling FJP, Duce IR.

PLoS One. 2017 Dec 11;12(12):e0187959. doi: 10.1371/journal.pone.0187959. eCollection 2017.

8.

Retromer stops beta-arrestin 1-mediated signaling from internalized cannabinoid 2 receptors.

Nogueras-Ortiz C, Roman-Vendrell C, Mateo-Semidey GE, Liao YH, Kendall DA, Yudowski GA.

Mol Biol Cell. 2017 Nov 15;28(24):3554-3561. doi: 10.1091/mbc.E17-03-0198. Epub 2017 Sep 27.

9.

Assessing Allosteric Modulation of CB1 at the Receptor and Cellular Levels.

Scott CE, Kendall DA.

Methods Enzymol. 2017;593:317-342. doi: 10.1016/bs.mie.2017.05.002. Epub 2017 Jul 5.

10.

Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities.

Khurana L, Mackie K, Piomelli D, Kendall DA.

Neuropharmacology. 2017 Sep 15;124:3-12. doi: 10.1016/j.neuropharm.2017.05.018. Epub 2017 May 17. Review.

11.

Cannabinoid Receptors in the Central Nervous System: Their Signaling and Roles in Disease.

Kendall DA, Yudowski GA.

Front Cell Neurosci. 2017 Jan 4;10:294. doi: 10.3389/fncel.2016.00294. eCollection 2016. Review.

12.

Pyrimidinyl Biphenylureas: Identification of New Lead Compounds as Allosteric Modulators of the Cannabinoid Receptor CB1.

Khurana L, Fu BQ, Duddupudi AL, Liao YH, Immadi SS, Kendall DA, Lu D.

J Med Chem. 2017 Feb 9;60(3):1089-1104. doi: 10.1021/acs.jmedchem.6b01448. Epub 2017 Jan 19.

13.

Δ9-Tetrahydrocannabinol reverses TNFα-induced increase in airway epithelial cell permeability through CB2 receptors.

Shang VC, Kendall DA, Roberts RE.

Biochem Pharmacol. 2016 Nov 15;120:63-71. doi: 10.1016/j.bcp.2016.09.008. Epub 2016 Sep 15.

PMID:
27641813
14.

Anti-nociceptive and desensitizing effects of olvanil on capsaicin-induced thermal hyperalgesia in the rat.

Alsalem M, Millns P, Altarifi A, El-Salem K, Chapman V, Kendall DA.

BMC Pharmacol Toxicol. 2016 Jul 21;17(1):31. doi: 10.1186/s40360-016-0074-9.

15.

Synthesis and biological evaluation of indole-2-carboxamides bearing photoactivatable functionalities as novel allosteric modulators for the cannabinoid CB1 receptor.

Qiao CJ, Ali HI, Ahn KH, Kolluru S, Kendall DA, Lu D.

Eur J Med Chem. 2016 Oct 4;121:517-529. doi: 10.1016/j.ejmech.2016.05.044. Epub 2016 May 24.

16.

Corticosterone and dopamine D2/D3 receptors mediate the motivation for voluntary wheel running in C57BL/6J mice.

Ebada ME, Kendall DA, Pardon MC.

Behav Brain Res. 2016 Sep 15;311:228-238. doi: 10.1016/j.bbr.2016.05.051. Epub 2016 May 24.

PMID:
27233827
17.

Mechanisms of Biased β-Arrestin-Mediated Signaling Downstream from the Cannabinoid 1 Receptor.

Delgado-Peraza F, Ahn KH, Nogueras-Ortiz C, Mungrue IN, Mackie K, Kendall DA, Yudowski GA.

Mol Pharmacol. 2016 Jun;89(6):618-29. doi: 10.1124/mol.115.103176. Epub 2016 Mar 23. Erratum in: Mol Pharmacol. 2016 Jul;90(1):62.

18.

Computational analysis of the CB1 carboxyl-terminus in the receptor-G protein complex.

Shim JY, Khurana L, Kendall DA.

Proteins. 2016 Apr;84(4):532-43. doi: 10.1002/prot.24999. Epub 2016 Feb 15.

19.

The endogenous cannabinoid anandamide increases human airway epithelial cell permeability through an arachidonic acid metabolite.

Shang VC, O'Sullivan SE, Kendall DA, Roberts RE.

Pharmacol Res. 2016 Mar;105:152-63. doi: 10.1016/j.phrs.2016.01.023. Epub 2016 Jan 22.

PMID:
26808080
20.

Computational Prediction and Biochemical Analyses of New Inverse Agonists for the CB1 Receptor.

Scott CE, Ahn KH, Graf ST, Goddard WA 3rd, Kendall DA, Abrol R.

J Chem Inf Model. 2016 Jan 25;56(1):201-12. doi: 10.1021/acs.jcim.5b00581. Epub 2016 Jan 5.

21.
22.

Minireview: From the bench, toward the clinic: therapeutic opportunities for cannabinoid receptor modulation.

Picone RP, Kendall DA.

Mol Endocrinol. 2015 Jun;29(6):801-13. doi: 10.1210/me.2015-1062. Epub 2015 Apr 13. Review.

23.

Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells.

Jean-Gilles L, Braitch M, Latif ML, Aram J, Fahey AJ, Edwards LJ, Robins RA, Tanasescu R, Tighe PJ, Gran B, Showe LC, Alexander SP, Chapman V, Kendall DA, Constantinescu CS.

Acta Physiol (Oxf). 2015 May;214(1):63-74. doi: 10.1111/apha.12474. Epub 2015 Mar 10.

24.
25.

A potential role for cannabinoid receptors in the therapeutic action of fenofibrate.

Priestley RS, Nickolls SA, Alexander SP, Kendall DA.

FASEB J. 2015 Apr;29(4):1446-55. doi: 10.1096/fj.14-263053. Epub 2014 Dec 30.

PMID:
25550466
26.

Evaluating the translational potential of progesterone treatment following transient cerebral ischaemia in male mice.

Wong R, Gibson CL, Kendall DA, Bath PM.

BMC Neurosci. 2014 Nov 29;15:131. doi: 10.1186/s12868-014-0131-5.

27.

(4-(Bis(4-fluorophenyl)methyl)piperazin-1-yl)(cyclohexyl)methanone hydrochloride (LDK1229): a new cannabinoid CB1 receptor inverse agonist from the class of benzhydryl piperazine analogs.

Mahmoud MM, Olszewska T, Liu H, Shore DM, Hurst DP, Reggio PH, Lu D, Kendall DA.

Mol Pharmacol. 2015 Feb;87(2):197-206. doi: 10.1124/mol.114.095471. Epub 2014 Nov 19.

28.

Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1.

Flores-Otero J, Ahn KH, Delgado-Peraza F, Mackie K, Kendall DA, Yudowski GA.

Nat Commun. 2014 Aug 1;5:4589. doi: 10.1038/ncomms5589.

29.

Simultaneous tissue profiling of eicosanoid and endocannabinoid lipid families in a rat model of osteoarthritis.

Wong A, Sagar DR, Ortori CA, Kendall DA, Chapman V, Barrett DA.

J Lipid Res. 2014 Sep;55(9):1902-13. doi: 10.1194/jlr.M048694. Epub 2014 Jul 25.

30.
31.

Analysis of SecA dimerization in solution.

Wowor AJ, Yan Y, Auclair SM, Yu D, Zhang J, May ER, Gross ML, Kendall DA, Cole JL.

Biochemistry. 2014 May 20;53(19):3248-60. doi: 10.1021/bi500348p. Epub 2014 May 9.

32.

Cannabidiol enhances microglial phagocytosis via transient receptor potential (TRP) channel activation.

Hassan S, Eldeeb K, Millns PJ, Bennett AJ, Alexander SP, Kendall DA.

Br J Pharmacol. 2014 May;171(9):2426-39. doi: 10.1111/bph.12615.

33.

Optimization of chemical functionalities of indole-2-carboxamides to improve allosteric parameters for the cannabinoid receptor 1 (CB1).

Khurana L, Ali HI, Olszewska T, Ahn KH, Damaraju A, Kendall DA, Lu D.

J Med Chem. 2014 Apr 10;57(7):3040-52. doi: 10.1021/jm5000112. Epub 2014 Mar 27.

34.

Cannabinoid CB2 receptors regulate central sensitization and pain responses associated with osteoarthritis of the knee joint.

Burston JJ, Sagar DR, Shao P, Bai M, King E, Brailsford L, Turner JM, Hathway GJ, Bennett AJ, Walsh DA, Kendall DA, Lichtman A, Chapman V.

PLoS One. 2013 Nov 25;8(11):e80440. doi: 10.1371/journal.pone.0080440. eCollection 2013.

35.

Endocannabinoid signalling in Alzheimer's disease.

Maroof N, Pardon MC, Kendall DA.

Biochem Soc Trans. 2013 Dec;41(6):1583-7. doi: 10.1042/BST20130140. Review.

PMID:
24256258
36.

International practice experiences in pharmacy education.

Cisneros RM, Jawaid SP, Kendall DA, McPherson CE 3rd, Mu K, Weston GS, Roberts KB.

Am J Pharm Educ. 2013 Nov 12;77(9):188. doi: 10.5688/ajpe779188.

37.

Fluorescence spectroscopy of soluble E. coli SPase I Δ2-75 reveals conformational changes in response to ligand binding.

Bhanu MK, Kendall DA.

Proteins. 2014 Apr;82(4):596-606. doi: 10.1002/prot.24429. Epub 2013 Oct 17.

38.

Molecular basis of cannabinoid CB1 receptor coupling to the G protein heterotrimer Gαiβγ: identification of key CB1 contacts with the C-terminal helix α5 of Gαi.

Shim JY, Ahn KH, Kendall DA.

J Biol Chem. 2013 Nov 8;288(45):32449-65. doi: 10.1074/jbc.M113.489153. Epub 2013 Oct 3.

39.

Structure-activity relationship study of indole-2-carboxamides identifies a potent allosteric modulator for the cannabinoid receptor 1 (CB1).

Mahmoud MM, Ali HI, Ahn KH, Damaraju A, Samala S, Pulipati VK, Kolluru S, Kendall DA, Lu D.

J Med Chem. 2013 Oct 24;56(20):7965-75. doi: 10.1021/jm4009828. Epub 2013 Oct 7.

40.

Lentiviral delivery of a vesicular glutamate transporter 1 (VGLUT1)-targeting short hairpin RNA vector into the mouse hippocampus impairs cognition.

King MV, Kurian N, Qin S, Papadopoulou N, Westerink BH, Cremers TI, Epping-Jordan MP, Le Poul E, Ray DE, Fone KC, Kendall DA, Marsden CA, Sharp TV.

Neuropsychopharmacology. 2014 Jan;39(2):464-76. doi: 10.1038/npp.2013.220. Epub 2013 Aug 28.

41.

Mapping of the SecA signal peptide binding site and dimeric interface by using the substituted cysteine accessibility method.

Bhanu MK, Zhao P, Kendall DA.

J Bacteriol. 2013 Oct;195(20):4709-15. doi: 10.1128/JB.00661-13. Epub 2013 Aug 9.

42.

Progesterone treatment for experimental stroke: an individual animal meta-analysis.

Wong R, Renton C, Gibson CL, Murphy SJ, Kendall DA, Bath PM; Progesterone Pre-Clinical Stroke Pooling Project Collaboration.

J Cereb Blood Flow Metab. 2013 Sep;33(9):1362-72. doi: 10.1038/jcbfm.2013.120. Epub 2013 Jul 10. Review.

43.

Defining the Escherichia coli SecA dimer interface residues through in vivo site-specific photo-cross-linking.

Yu D, Wowor AJ, Cole JL, Kendall DA.

J Bacteriol. 2013 Jun;195(12):2817-25. doi: 10.1128/JB.02269-12. Epub 2013 Apr 12.

44.

Distinct roles of β-arrestin 1 and β-arrestin 2 in ORG27569-induced biased signaling and internalization of the cannabinoid receptor 1 (CB1).

Ahn KH, Mahmoud MM, Shim JY, Kendall DA.

J Biol Chem. 2013 Apr 5;288(14):9790-800. doi: 10.1074/jbc.M112.438804. Epub 2013 Feb 28.

46.

The contribution of the endogenous TRPV1 ligands 9-HODE and 13-HODE to nociceptive processing and their role in peripheral inflammatory pain mechanisms.

Alsalem M, Wong A, Millns P, Arya PH, Chan MS, Bennett A, Barrett DA, Chapman V, Kendall DA.

Br J Pharmacol. 2013 Apr;168(8):1961-74. doi: 10.1111/bph.12092.

47.

Profiling two indole-2-carboxamides for allosteric modulation of the CB1 receptor.

Ahn KH, Mahmoud MM, Samala S, Lu D, Kendall DA.

J Neurochem. 2013 Mar;124(5):584-9. doi: 10.1111/jnc.12115. Epub 2013 Jan 7.

48.

Molecular basis for dramatic changes in cannabinoid CB1 G protein-coupled receptor activation upon single and double point mutations.

Scott CE, Abrol R, Ahn KH, Kendall DA, Goddard WA 3rd.

Protein Sci. 2013 Jan;22(1):101-13. doi: 10.1002/pro.2192.

49.

Progesterone pharmacokinetics in the mouse: implications for potential stroke therapy.

Wong R, Ray D, Kendall DA.

J Pharm Pharmacol. 2012 Nov;64(11):1614-20. doi: 10.1111/j.2042-7158.2012.01537.x. Epub 2012 Jun 4.

PMID:
23058048
50.

Probing the interaction of SR141716A with the CB1 receptor.

Shim JY, Bertalovitz AC, Kendall DA.

J Biol Chem. 2012 Nov 9;287(46):38741-54. doi: 10.1074/jbc.M112.390955. Epub 2012 Sep 20.

Supplemental Content

Loading ...
Support Center