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Items: 20

1.
2.

Mechanism-Based Inactivation of Human Cytochrome P450 2B6 by Chlorpyrifos.

D'Agostino J, Zhang H, Kenaan C, Hollenberg PF.

Chem Res Toxicol. 2015 Jul 20;28(7):1484-95. doi: 10.1021/acs.chemrestox.5b00156. Epub 2015 Jun 30.

3.

Effects of P6 stimulation on postoperative nausea and vomiting in laparoscopic cholecystectomy patients.

Carr KL, Johnson FE, Kenaan CA, Welton JM.

J Perianesth Nurs. 2015 Apr;30(2):143-50. doi: 10.1016/j.jopan.2014.04.005. Erratum in: J Perianesth Nurs. 2015 Jun;30(3):238.

PMID:
25813300
4.

The effect of ritonavir on human CYP2B6 catalytic activity: heme modification contributes to the mechanism-based inactivation of CYP2B6 and CYP3A4 by ritonavir.

Lin HL, D'Agostino J, Kenaan C, Calinski D, Hollenberg PF.

Drug Metab Dispos. 2013 Oct;41(10):1813-24. doi: 10.1124/dmd.113.053108. Epub 2013 Jul 25.

5.

High-throughput fluorescence assay for cytochrome P450 mechanism-based inactivators.

Kenaan C, Zhang H, Hollenberg PF.

Methods Mol Biol. 2013;987:61-9. doi: 10.1007/978-1-62703-321-3_5.

PMID:
23475667
6.

Interactions between CYP2E1 and CYP2B4: effects on affinity for NADPH-cytochrome P450 reductase and substrate metabolism.

Kenaan C, Shea EV, Lin HL, Zhang H, Pratt-Hyatt MJ, Hollenberg PF.

Drug Metab Dispos. 2013 Jan;41(1):101-10. doi: 10.1124/dmd.112.046094. Epub 2012 Oct 5.

7.

Reaction of human cytochrome P450 3A4 with peroxynitrite: nitrotyrosine formation on the proximal side impairs its interaction with NADPH-cytochrome P450 reductase.

Lin HL, Kenaan C, Zhang H, Hollenberg PF.

Chem Res Toxicol. 2012 Dec 17;25(12):2642-53. doi: 10.1021/tx3002753. Epub 2012 Oct 16.

8.

Inhibition of bupropion metabolism by selegiline: mechanism-based inactivation of human CYP2B6 and characterization of glutathione and peptide adducts.

Sridar C, Kenaan C, Hollenberg PF.

Drug Metab Dispos. 2012 Dec;40(12):2256-66. doi: 10.1124/dmd.112.046979. Epub 2012 Aug 30.

9.

Identification of the residue in human CYP3A4 that is covalently modified by bergamottin and the reactive intermediate that contributes to the grapefruit juice effect.

Lin HL, Kenaan C, Hollenberg PF.

Drug Metab Dispos. 2012 May;40(5):998-1006. doi: 10.1124/dmd.112.044560. Epub 2012 Feb 16.

10.
11.

Uncovering the role of hydrophobic residues in cytochrome P450-cytochrome P450 reductase interactions.

Kenaan C, Zhang H, Shea EV, Hollenberg PF.

Biochemistry. 2011 May 17;50(19):3957-67. doi: 10.1021/bi1020748. Epub 2011 Apr 22.

12.

A quantitative high-throughput 96-well plate fluorescence assay for mechanism-based inactivators of cytochromes P450 exemplified using CYP2B6.

Kenaan C, Zhang H, Hollenberg PF.

Nat Protoc. 2010 Sep;5(10):1652-8. doi: 10.1038/nprot.2010.125. Epub 2010 Sep 23.

13.

Targeting of the highly conserved threonine 302 residue of cytochromes P450 2B family during mechanism-based inactivation by aryl acetylenes.

Zhang H, Lin HL, Kenaan C, Hollenberg PF.

Arch Biochem Biophys. 2011 Mar 1;507(1):135-43. doi: 10.1016/j.abb.2010.09.006. Epub 2010 Sep 15. Review.

14.

Effect of conformational dynamics on substrate recognition and specificity as probed by the introduction of a de novo disulfide bond into cytochrome P450 2B1.

Zhang H, Kenaan C, Hamdane D, Hoa GH, Hollenberg PF.

J Biol Chem. 2009 Sep 18;284(38):25678-86. doi: 10.1074/jbc.M109.032748. Epub 2009 Jul 15.

15.

A multicenter evaluation of the time-course of action of two doses of rapacuronium after early and late reversal with neostigmine.

Larijani GE, Donati F, Bikhazi G, Bartkowski R, Kenaan CA, Plaud B, Goldberg ME.

Anesth Analg. 2001 Aug;93(2):370-4 , 3rd contents page.

PMID:
11473863
16.

Pharmacodynamics and intubating conditions of cisatracurium in children during halothane and opioid anesthesia.

Kenaan CA, Estacio RL, Bikhazi GB.

J Clin Anesth. 2000 May;12(3):173-6.

PMID:
10869913
17.

Rapacuronium for modified rapid sequence induction in elective caesarean section: neuromuscular blocking effects and safety compared with succinylcholine, and placental transfer.

Abouleish EI, Abboud TK, Bikhazi G, Kenaan CA, Mroz L, Zhu J, Lee J.

Br J Anaesth. 1999 Dec;83(6):862-7. Erratum in: Br J Anaesth 2000 Mar;84(3):428. Abboud TS [corrected to Abboud TK].

18.

Neuromuscular effects of rapacuronium in pediatric patients during nitrous oxide-halothane anesthesia: comparison with mivacurium.

Brandom BW, Margolis JO, Bikhazi GB, Ross AK, Ginsberg B, Dear G, Kenaan CA, Eck JB, Woelfel SK, Lloyd ME.

Can J Anaesth. 2000 Feb;47(2):143-9.

PMID:
10674508
19.

Influence of the priming technique on pharmacodynamics and intubating conditions of cisatracurium.

Deepika K, Kenaan CA, Bikhazi GB, Martineau DB.

J Clin Anesth. 1999 Nov;11(7):572-5.

PMID:
10624642
20.

Negative pressure pulmonary edema after acute upper airway obstruction.

Deepika K, Kenaan CA, Barrocas AM, Fonseca JJ, Bikazi GB.

J Clin Anesth. 1997 Aug;9(5):403-8.

PMID:
9257208

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