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Clinical Outcomes among Patients with Drug-resistant Tuberculosis receiving Bedaquiline or Delamanid Containing Regimens.

Kempker RR, Mikiashvili L, Zhao Y, Benkeser D, Barbakadze K, Bablishvili N, Avaliani Z, Peloquin CA, Blumberg HM, Kipiani M.

Clin Infect Dis. 2019 Nov 12. pii: ciz1107. doi: 10.1093/cid/ciz1107. [Epub ahead of print]


Time to Review the Infectious Diseases Society of America Diabetic Foot Infection Classification System and Merge the Moderate and Severe Infection Categories?

Schechter MC, Kempker RR.

Clin Infect Dis. 2019 Sep 17. pii: ciz923. doi: 10.1093/cid/ciz923. [Epub ahead of print] No abstract available.


Rates and risk factors for nephrotoxicity and ototoxicity among tuberculosis patients in Tbilisi, Georgia.

Buziashvili M, Mirtskhulava V, Kipiani M, Blumberg HM, Baliashvili D, Magee MJ, Furin JJ, Tukvadze N, Kempker RR.

Int J Tuberc Lung Dis. 2019 Sep 1;23(9):1005-1011. doi: 10.5588/ijtld.18.0626.


A Pharmacology Perspective of Simultaneous Tuberculosis and Hepatitis C Treatment.

Kempker RR, Alghamdi WA, Al-Shaer MH, Burch G, Peloquin CA.

Antimicrob Agents Chemother. 2019 Oct 7. pii: AAC.01215-19. doi: 10.1128/AAC.01215-19. [Epub ahead of print] Review.


The rapid scale up of medical education in Ethiopia: Medical student experiences and the role of e-learning at Addis Ababa University.

Kelly CM, Vins H, Spicer JO, Mengistu BS, Wilson DR, Derbew M, Bekele A, Mariam DH, Del Rio C, Kempker RR, Comeau DL, Blumberg HM.

PLoS One. 2019 Sep 5;14(9):e0221989. doi: 10.1371/journal.pone.0221989. eCollection 2019.


Disparity in Quality of Infectious Disease vs Addiction Care Among Patients With Injection Drug Use-Associated Staphylococcus aureus Bacteremia.

Serota DP, Niehaus ED, Schechter MC, Jacob JT, Jones J, Ray SM, Kelley CF, Kempker RR.

Open Forum Infect Dis. 2019 Jun 18;6(7):ofz289. doi: 10.1093/ofid/ofz289. eCollection 2019 Jul.


High Yield of Active Tuberculosis Case Finding Among HIV-Infected Patients Using Xpert MTB/RIF Testing.

Kempker RR, Chkhartishvili N, Kinkladze I, Schechter MC, Harrington K, Rukhadze N, Dzigua L, Tserstvadze T, Del Rio C, Blumberg HM, Tukvadze N.

Open Forum Infect Dis. 2019 May 17;6(6):ofz233. doi: 10.1093/ofid/ofz233. eCollection 2019 Jun.


Fluoroquinolones in Drug-Resistant Tuberculosis: Culture Conversion and Pharmacokinetic/Pharmacodynamic Target Attainment To Guide Dose Selection.

Al-Shaer MH, Alghamdi WA, Alsultan A, An G, Ahmed S, Alkabab Y, Banu S, Barbakadze K, Houpt E, Kipiani M, Mikiashvili L, Cegielski JP, Kempker RR, Heysell SK, Peloquin CA.

Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e00279-19. doi: 10.1128/AAC.00279-19. Print 2019 Jul.


Long-term Follow-up Reveals High Posttreatment Mortality Rate Among Patients With Extensively Drug-Resistant Tuberculosis in the Country of Georgia.

Frank M, Adamashvili N, Lomtadze N, Kokhreidze E, Avaliani Z, Kempker RR, Blumberg HM.

Open Forum Infect Dis. 2019 Mar 29;6(4):ofz152. doi: 10.1093/ofid/ofz152. eCollection 2019 Apr.


Cycloserine Population Pharmacokinetics and Pharmacodynamics in Patients with Tuberculosis.

Alghamdi WA, Alsultan A, Al-Shaer MH, An G, Ahmed S, Alkabab Y, Banu S, Barbakadze K, Houpt E, Kipiani M, Mikiashvili L, Schmidt S, Heysell SK, Kempker RR, Cegielski JP, Peloquin CA.

Antimicrob Agents Chemother. 2019 Apr 25;63(5). pii: e00055-19. doi: 10.1128/AAC.00055-19. Print 2019 May.


Pulmonary function and respiratory health after successful treatment of drug-resistant tuberculosis.

Vashakidze SA, Kempker JA, Jakobia NA, Gogishvili SG, Nikolaishvili KA, Goginashvili LM, Magee MJ, Kempker RR.

Int J Infect Dis. 2019 May;82:66-72. doi: 10.1016/j.ijid.2019.02.039. Epub 2019 Mar 5.


Hospital Onset Varicella Central Nervous System Vasculitis in a Patient with HIV Infection.

Harrington KRV, Rhyner P, Kempker RR.

AIDS Res Hum Retroviruses. 2019 Apr;35(4):357-358. doi: 10.1089/aid.2018.0262. Epub 2019 Feb 4. No abstract available.


A survey of the tuberculosis physician workforce in the country of Georgia.

Graciaa DS, Machaidze M, Kipiani M, Buziashvili M, Barbakadze K, Avaliani Z, Kempker RR.

Int J Tuberc Lung Dis. 2018 Nov 1;22(11):1286-1292. doi: 10.5588/ijtld.18.0085.


High-resolution plasma metabolomics analysis to detect Mycobacterium tuberculosis-associated metabolites that distinguish active pulmonary tuberculosis in humans.

Collins JM, Walker DI, Jones DP, Tukvadze N, Liu KH, Tran VT, Uppal K, Frediani JK, Easley KA, Shenvi N, Khadka M, Ortlund EA, Kempker RR, Blumberg HM, Ziegler TR.

PLoS One. 2018 Oct 11;13(10):e0205398. doi: 10.1371/journal.pone.0205398. eCollection 2018.


Global Health and the Infectious Diseases Physician-Scientist Workforce.

Kempker RR, Blumberg HM.

J Infect Dis. 2019 Feb 23;219(6):1007-1008. doi: 10.1093/infdis/jiy593. No abstract available.


A population-based tuberculosis contact investigation in the country of Georgia.

Baliashvili D, Kempker RR, Blumberg HM, Kuchukhidze G, Merabishvili T, Aslanikashvili A, Magee MJ.

Public Health Action. 2018 Sep 21;8(3):110-117. doi: 10.5588/pha.18.0024.


Treatment correlates of successful outcomes in pulmonary multidrug-resistant tuberculosis: an individual patient data meta-analysis.

Collaborative Group for the Meta-Analysis of Individual Patient Data in MDR-TB treatment–2017, Ahmad N, Ahuja SD, Akkerman OW, Alffenaar JC, Anderson LF, Baghaei P, Bang D, Barry PM, Bastos ML, Behera D, Benedetti A, Bisson GP, Boeree MJ, Bonnet M, Brode SK, Brust JCM, Cai Y, Caumes E, Cegielski JP, Centis R, Chan PC, Chan ED, Chang KC, Charles M, Cirule A, Dalcolmo MP, D'Ambrosio L, de Vries G, Dheda K, Esmail A, Flood J, Fox GJ, Fréchet-Jachym M, Fregona G, Gayoso R, Gegia M, Gler MT, Gu S, Guglielmetti L, Holtz TH, Hughes J, Isaakidis P, Jarlsberg L, Kempker RR, Keshavjee S, Khan FA, Kipiani M, Koenig SP, Koh WJ, Kritski A, Kuksa L, Kvasnovsky CL, Kwak N, Lan Z, Lange C, Laniado-Laborín R, Lee M, Leimane V, Leung CC, Leung EC, Li PZ, Lowenthal P, Maciel EL, Marks SM, Mase S, Mbuagbaw L, Migliori GB, Milanov V, Miller AC, Mitnick CD, Modongo C, Mohr E, Monedero I, Nahid P, Ndjeka N, O'Donnell MR, Padayatchi N, Palmero D, Pape JW, Podewils LJ, Reynolds I, Riekstina V, Robert J, Rodriguez M, Seaworth B, Seung KJ, Schnippel K, Shim TS, Singla R, Smith SE, Sotgiu G, Sukhbaatar G, Tabarsi P, Tiberi S, Trajman A, Trieu L, Udwadia ZF, van der Werf TS, Veziris N, Viiklepp P, Vilbrun SC, Walsh K, Westenhouse J, Yew WW, Yim JJ, Zetola NM, Zignol M, Menzies D.

Lancet. 2018 Sep 8;392(10150):821-834. doi: 10.1016/S0140-6736(18)31644-1. Review.


Treatment Complexities Among Patients with Tuberculosis in a High HIV Prevalence Cohort in the United States.

Bizune DJ, Kempker RR, Kagei M, Yamin A, Mohamed O, Holland DP, Oladele A, Wang YF, Rebolledo PA, Blumberg HM, Ray SM, Schechter MC.

AIDS Res Hum Retroviruses. 2018 Sep 11. doi: 10.1089/AID.2018.0126. [Epub ahead of print]


Mentoring in Global Health: Formative Evaluation of Tuberculosis Research Training Programs in Ethiopia and Georgia.

Comeau DL, Mishkin K, Tukvadze N, Avaliani Z, Kempker RR, Sthreshley L, Magee MJ, Eisen H, Mariam DH, Aseffa A, Blumberg HM.

Am J Trop Med Hyg. 2018 Sep;99(3):565-577. doi: 10.4269/ajtmh.17-0746. Epub 2018 Jul 12.


High utility of active tuberculosis case finding in an Ethiopian prison.

Merid Y, Woldeamanuel Y, Abebe M, Datiko DG, Hailu T, Habtamu G, Assefa G, Kempker RR, Blumberg HM, Aseffa A.

Int J Tuberc Lung Dis. 2018 May 1;22(5):524-529. doi: 10.5588/ijtld.17.0635.


Challenges Across the HIV Care Continuum for Patients With HIV/TB Co-infection in Atlanta, GA [corrected].

Schechter MC, Bizune D, Kagei M, Holland DP, Del Rio C, Yamin A, Mohamed O, Oladele A, Wang YF, Rebolledo PA, Ray SM, Kempker RR.

Open Forum Infect Dis. 2018 Mar 21;5(4):ofy063. doi: 10.1093/ofid/ofy063. eCollection 2018 Apr. Erratum in: Open Forum Infect Dis. 2018 Apr 30;5(4):ofy079. Open Forum Infect Dis. 2018 Nov 26;5(11):ofy279.


False-Positive Tuberculin Skin Test Results Among Low-Risk Healthcare Workers Following Implementation of Fifty-Dose Vials of Purified Protein Derivative.

Collins JM, Hunter M, Gordon W, Kempker RR, Blumberg HM, Ray SM.

Infect Control Hosp Epidemiol. 2018 Jun;39(6):750-752. doi: 10.1017/ice.2018.59. Epub 2018 Apr 2.


A comparison of linezolid lung tissue concentrations among patients with drug-resistant tuberculosis.

Kempker RR, Heinrichs MT, Nikolaishvili K, Sabulua I, Bablishvili N, Gogishvili S, Avaliani Z, Little BP, Bernheim A, Derendorf H, Blumberg HM, Vashakidze S, Peloquin CA.

Eur Respir J. 2018 Feb 7;51(2). pii: 1702166. doi: 10.1183/13993003.02166-2017. Print 2018 Feb. No abstract available.


The Impact of a Fogarty International Center-Supported Tuberculosis Research Training Program in the Country of Georgia.

Kempker RR, Tukvadze N, Sthreshley L, Sharling L, Comeau DL, Magee MJ, Del Rio C, Avaliani Z, Blumberg HM.

Am J Trop Med Hyg. 2018 Apr;98(4):1069-1074. doi: 10.4269/ajtmh.17-0667. Epub 2018 Feb 1.


Cost-effectiveness of WHO-Recommended Algorithms for TB Case Finding at Ethiopian HIV Clinics.

Adelman MW, McFarland DA, Tsegaye M, Aseffa A, Kempker RR, Blumberg HM.

Open Forum Infect Dis. 2017 Dec 23;5(1):ofx269. doi: 10.1093/ofid/ofx269. eCollection 2018 Jan.


Reply to Chang et al., "Pyrazinamide Is a Two-Edged Sword: Do WHO Guidelines Matter?"

Peloquin CA, Kempker RR.

Antimicrob Agents Chemother. 2017 Dec 21;62(1). pii: e01937-17. doi: 10.1128/AAC.01937-17. Print 2018 Jan. No abstract available.


Moxifloxacin target site concentrations in patients with pulmonary TB utilizing microdialysis: a clinical pharmacokinetic study.

Heinrichs MT, Vashakidze S, Nikolaishvili K, Sabulua I, Tukvadze N, Bablishvili N, Gogishvili S, Little BP, Bernheim A, Guarner J, Peloquin CA, Blumberg HM, Derendorf H, Kempker RR.

J Antimicrob Chemother. 2018 Feb 1;73(2):477-483. doi: 10.1093/jac/dkx421.


Asymptomatic Cardiovascular Syphilis With Aortic Regurgitation Requiring Surgical Repair in an HIV-Infected Patient.

Graciaa DS, Mosunjac MB, Workowski KA, Kempker RR.

Open Forum Infect Dis. 2017 Sep 14;4(4):ofx198. doi: 10.1093/ofid/ofx198. eCollection 2017 Fall.


Isoniazid Monoresistance and Rate of Culture Conversion among Patients in the State of Georgia with Confirmed Tuberculosis, 2009-2014.

Salindri AD, Sales RF, DiMiceli L, Schechter MC, Kempker RR, Magee MJ.

Ann Am Thorac Soc. 2018 Mar;15(3):331-340. doi: 10.1513/AnnalsATS.201702-147OC.


Peculiar purulence: Hypervirulent Klebsiella pneumoniae causing pyomyositis.

Mgbemena O, Serota DP, Kumar S, Wozniak JE, Weiss DS, Kempker RR.

Int J Infect Dis. 2017 Dec;65:90-92. doi: 10.1016/j.ijid.2017.09.030. Epub 2017 Oct 10.


Time to Sputum Culture Conversion and Treatment Outcomes Among Patients with Isoniazid-Resistant Tuberculosis in Atlanta, Georgia.

Schechter MC, Bizune D, Kagei M, Machaidze M, Holland DP, Oladele A, Wang YF, Rebolledo PA, Ray SM, Kempker RR.

Clin Infect Dis. 2017 Nov 13;65(11):1862-1871. doi: 10.1093/cid/cix686.


Reply to Srivastava et al., "pH Conditions under Which Pyrazinamide Works in Humans".

Kempker RR, Peloquin CA, Blumberg HM, Vashakidze S.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e01120-17. doi: 10.1128/AAC.01120-17. Print 2017 Sep. No abstract available.


Smoking behavior and beliefs about the impact of smoking on anti-tuberculosis treatment among health care workers.

Magee MJ, Darchia L, Kipiani M, Chakhaia T, Kempker RR, Tukvadze N, Berg CJ, Blumberg HM.

Int J Tuberc Lung Dis. 2017 Sep 1;21(9):1049-1055. doi: 10.5588/ijtld.17.0023. Epub 2017 Jun 29.


Impact of gyrB and eis Mutations in Improving Detection of Second-Line-Drug Resistance among Mycobacterium tuberculosis Isolates from Georgia.

Bablishvili N, Tukvadze N, Shashkina E, Mathema B, Gandhi NR, Blumberg HM, Kempker RR.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e01921-16. doi: 10.1128/AAC.01921-16. Print 2017 Sep.


Lung Tissue Concentrations of Pyrazinamide among Patients with Drug-Resistant Pulmonary Tuberculosis.

Kempker RR, Heinrichs MT, Nikolaishvili K, Sabulua I, Bablishvili N, Gogishvili S, Avaliani Z, Tukvadze N, Little B, Bernheim A, Read TD, Guarner J, Derendorf H, Peloquin CA, Blumberg HM, Vashakidze S.

Antimicrob Agents Chemother. 2017 May 24;61(6). pii: e00226-17. doi: 10.1128/AAC.00226-17. Print 2017 Jun.


pncA Gene Mutations Associated with Pyrazinamide Resistance in Drug-Resistant Tuberculosis, South Africa and Georgia.

Allana S, Shashkina E, Mathema B, Bablishvili N, Tukvadze N, Shah NS, Kempker RR, Blumberg HM, Moodley P, Mlisana K, Brust JC, Gandhi NR.

Emerg Infect Dis. 2017 Mar;23(3):491-495. doi: 10.3201/eid2303.161034.


The Effects of First-Line Anti-Tuberculosis Drugs on the Actions of Vitamin D in Human Macrophages.

Chesdachai S, Zughaier SM, Hao L, Kempker RR, Blumberg HM, Ziegler TR, Tangpricha V.

J Clin Transl Endocrinol. 2016 Dec;6:23-29. doi: 10.1016/j.jcte.2016.08.005.


Predictors of Latent Tuberculosis Infection Treatment After Introduction of a New Regimen: A Retrospective Cohort Study at an Inner City Clinic.

Yamin A, Bornstein E, Hensel R, Mohamed O, Kempker RR.

Open Forum Infect Dis. 2016 Apr 21;3(4):ofw082. eCollection 2016 Oct.


Point-of-Care Testing for Cryptococcal Disease Among Hospitalized Human Immunodeficiency Virus-Infected Adults in Ethiopia.

Mamuye AT, Bornstein E, Temesgen O, Blumberg HM, Kempker RR.

Am J Trop Med Hyg. 2016 Oct 5;95(4):786-792. Epub 2016 Aug 15.


Diabetes Reduces the Rate of Sputum Culture Conversion in Patients With Newly Diagnosed Multidrug-Resistant Tuberculosis.

Salindri AD, Kipiani M, Kempker RR, Gandhi NR, Darchia L, Tukvadze N, Blumberg HM, Magee MJ.

Open Forum Infect Dis. 2016 Jun 16;3(3):ofw126. doi: 10.1093/ofid/ofw126. eCollection 2016 Sep.


Diabetes mellitus and extrapulmonary tuberculosis: site distribution and risk of mortality.

Magee MJ, Foote M, Ray SM, Gandhi NR, Kempker RR.

Epidemiol Infect. 2016 Jul;144(10):2209-16. doi: 10.1017/S0950268816000364. Epub 2016 Mar 1.


Metabolomics and Mycobacterial Disease: Don't Forget the Bioinformatics.

Collins JM, Kempker RR, Ziegler TR, Blumberg HM, Jones DP.

Ann Am Thorac Soc. 2016 Jan;13(1):141-2. doi: 10.1513/AnnalsATS.201510-676LE. No abstract available.


Contacts of retreatment tuberculosis cases with a prior poor treatment outcome are at increased risk of latent tuberculosis infection.

Baliashvili D, Magee MJ, Kempker RR, Kuchukhidze G, Aslanikashvili A, Blumberg HM.

Int J Infect Dis. 2016 Feb;43:49-50. doi: 10.1016/j.ijid.2015.12.015. Epub 2015 Dec 25.


Increased risk of latent tuberculous infection among persons with pre-diabetes and diabetes mellitus.

Hensel RL, Kempker RR, Tapia J, Oladele A, Blumberg HM, Magee MJ.

Int J Tuberc Lung Dis. 2016 Jan;20(1):71-8. doi: 10.5588/ijtld.15.0457.


Intensified tuberculosis case finding among HIV-infected persons using a WHO symptom screen and Xpert(®) MTB/RIF.

Adelman MW, Tsegaye M, Kempker RR, Alebachew T, Haile K, Tesfaye A, Aseffa A, Blumberg HM.

Int J Tuberc Lung Dis. 2015 Oct;19(10):1197-203. doi: 10.5588/ijtld.15.0230.


High-dose vitamin D3 in adults with pulmonary tuberculosis: a double-blind randomized controlled trial.

Tukvadze N, Sanikidze E, Kipiani M, Hebbar G, Easley KA, Shenvi N, Kempker RR, Frediani JK, Mirtskhulava V, Alvarez JA, Lomtadze N, Vashakidze L, Hao L, Del Rio C, Tangpricha V, Blumberg HM, Ziegler TR.

Am J Clin Nutr. 2015 Nov;102(5):1059-69. doi: 10.3945/ajcn.115.113886. Epub 2015 Sep 23.


Risk factors associated with loss to follow-up among multidrug-resistant tuberculosis patients in Georgia.

Kuchukhidze G, Kumar AM, de Colombani P, Khogali M, Nanava U, Blumberg HM, Kempker RR.

Public Health Action. 2014 Oct 21;4(Suppl 2):S41-6. doi: 10.5588/pha.14.0048.


Increase in Lymphadenitis Cases after Shift in BCG Vaccine Strain.

Kuchukhidze G, Kasradze A, Dolakidze T, Baliashvili D, Merabishvili T, Blumberg HM, Kempker RR.

Emerg Infect Dis. 2015 Sep;21(9):1677-9. doi: 10.3201/2109.150289. No abstract available.


Tobacco smoking and tuberculosis treatment outcomes: a prospective cohort study in Georgia.

Gegia M, Magee MJ, Kempker RR, Kalandadze I, Chakhaia T, Golub JE, Blumberg HM.

Bull World Health Organ. 2015 Jun 1;93(6):390-9. doi: 10.2471/BLT.14.147439. Epub 2015 Mar 30.


Acquired Drug Resistance in Mycobacterium tuberculosis and Poor Outcomes among Patients with Multidrug-Resistant Tuberculosis.

Kempker RR, Kipiani M, Mirtskhulava V, Tukvadze N, Magee MJ, Blumberg HM.

Emerg Infect Dis. 2015 Jun;21(6):992-1001. doi: 10.3201/eid2106.141873.

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