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Items: 1 to 50 of 60

1.

The biotin-ligating protein BPL-1 is critical for lipid biosynthesis and polarization of the Caenorhabditis elegans embryo.

Watts JS, Morton DG, Kemphues KJ, Watts JL.

J Biol Chem. 2018 Jan 12;293(2):610-622. doi: 10.1074/jbc.M117.798553. Epub 2017 Nov 20.

2.

Horvitz and Sulston on Caenorhabditis elegans Cell Lineage Mutants.

Kemphues KJ.

Genetics. 2016 Aug;203(4):1485-7. doi: 10.1534/genetics.116.193003. No abstract available.

3.

The Deubiquitylase MATH-33 Controls DAF-16 Stability and Function in Metabolism and Longevity.

Heimbucher T, Liu Z, Bossard C, McCloskey R, Carrano AC, Riedel CG, Tanasa B, Klammt C, Fonslow BR, Riera CE, Lillemeier BF, Kemphues K, Yates JR 3rd, O'Shea C, Hunter T, Dillin A.

Cell Metab. 2015 Jul 7;22(1):151-63. doi: 10.1016/j.cmet.2015.06.002.

4.

High Runx1 levels promote a reversible, more-differentiated cell state in hair-follicle stem cells during quiescence.

Lee SE, Sada A, Zhang M, McDermitt DJ, Lu SY, Kemphues KJ, Tumbar T.

Cell Rep. 2014 Feb 13;6(3):499-513. doi: 10.1016/j.celrep.2013.12.039. Epub 2014 Jan 23. Erratum in: Cell Rep. 2014 Feb 13;6(3):592.

5.

Small molecule injection into single-cell C. elegans embryos via carbon-reinforced nanopipettes.

Brennan LD, Roland T, Morton DG, Fellman SM, Chung S, Soltani M, Kevek JW, McEuen PM, Kemphues KJ, Wang MD.

PLoS One. 2013 Sep 26;8(9):e75712. doi: 10.1371/journal.pone.0075712. eCollection 2013.

6.

PAR-2, LGL-1 and the CDC-42 GAP CHIN-1 act in distinct pathways to maintain polarity in the C. elegans embryo.

Beatty A, Morton DG, Kemphues K.

Development. 2013 May;140(9):2005-14. doi: 10.1242/dev.088310. Epub 2013 Mar 27.

7.

Nonmuscle myosin IIB links cytoskeleton to IRE1α signaling during ER stress.

He Y, Beatty A, Han X, Ji Y, Ma X, Adelstein RS, Yates JR 3rd, Kemphues K, Qi L.

Dev Cell. 2012 Dec 11;23(6):1141-52. doi: 10.1016/j.devcel.2012.11.006.

8.

Deubiquitylation machinery is required for embryonic polarity in Caenorhabditis elegans.

McCloskey RJ, Kemphues KJ.

PLoS Genet. 2012;8(11):e1003092. doi: 10.1371/journal.pgen.1003092. Epub 2012 Nov 29.

9.

A genome-wide RNAi screen for enhancers of par mutants reveals new contributors to early embryonic polarity in Caenorhabditis elegans.

Morton DG, Hoose WA, Kemphues KJ.

Genetics. 2012 Nov;192(3):929-42. doi: 10.1534/genetics.112.143727. Epub 2012 Aug 10.

10.

Z-line formins promote contractile lattice growth and maintenance in striated muscles of C. elegans.

Mi-Mi L, Votra S, Kemphues K, Bretscher A, Pruyne D.

J Cell Biol. 2012 Jul 9;198(1):87-102. doi: 10.1083/jcb.201202053. Epub 2012 Jul 2.

11.

Fertilization and Establishment of Polarity in the Embryo.

Kemphues KJ, Strome S.

In: Riddle DL, Blumenthal T, Meyer BJ, Priess JR, editors. C. elegans II. 2nd edition. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 1997. No abstract available. Chapter 13.

12.

The C. elegans homolog of Drosophila Lethal giant larvae functions redundantly with PAR-2 to maintain polarity in the early embryo.

Beatty A, Morton D, Kemphues K.

Development. 2010 Dec;137(23):3995-4004. doi: 10.1242/dev.056028. Epub 2010 Nov 1.

13.

Different domains of C. elegans PAR-3 are required at different times in development.

Li B, Kim H, Beers M, Kemphues K.

Dev Biol. 2010 Aug 15;344(2):745-57. doi: 10.1016/j.ydbio.2010.05.506. Epub 2010 Jun 4.

14.

Control of mitotic and meiotic centriole duplication by the Plk4-related kinase ZYG-1.

Peters N, Perez DE, Song MH, Liu Y, Müller-Reichert T, Caron C, Kemphues KJ, O'Connell KF.

J Cell Sci. 2010 Mar 1;123(Pt 5):795-805. doi: 10.1242/jcs.050682. Epub 2010 Feb 9.

15.

Binding to PKC-3, but not to PAR-3 or to a conventional PDZ domain ligand, is required for PAR-6 function in C. elegans.

Li J, Kim H, Aceto DG, Hung J, Aono S, Kemphues KJ.

Dev Biol. 2010 Apr 1;340(1):88-98. doi: 10.1016/j.ydbio.2010.01.023. Epub 2010 Feb 1.

16.

Essential genes.

Kemphues K.

WormBook. 2005 Dec 24:1-7. Review.

17.

Interaction of PAR-6 with CDC-42 is required for maintenance but not establishment of PAR asymmetry in C. elegans.

Aceto D, Beers M, Kemphues KJ.

Dev Biol. 2006 Nov 15;299(2):386-97. Epub 2006 Aug 9.

18.

Depletion of the co-chaperone CDC-37 reveals two modes of PAR-6 cortical association in C. elegans embryos.

Beers M, Kemphues K.

Development. 2006 Oct;133(19):3745-54. Epub 2006 Aug 30.

19.

Nucleoporins NPP-1, NPP-3, NPP-4, NPP-11 and NPP-13 are required for proper spindle orientation in C. elegans.

Schetter A, Askjaer P, Piano F, Mattaj I, Kemphues K.

Dev Biol. 2006 Jan 15;289(2):360-71. Epub 2005 Dec 2.

20.

PAR-3 is required for epithelial cell polarity in the distal spermatheca of C. elegans.

Aono S, Legouis R, Hoose WA, Kemphues KJ.

Development. 2004 Jun;131(12):2865-74. Epub 2004 May 19.

21.

Polarization of the C. elegans zygote proceeds via distinct establishment and maintenance phases.

Cuenca AA, Schetter A, Aceto D, Kemphues K, Seydoux G.

Development. 2003 Apr;130(7):1255-65.

22.

PAR-1 is required for morphogenesis of the Caenorhabditis elegans vulva.

Hurd DD, Kemphues KJ.

Dev Biol. 2003 Jan 1;253(1):54-65.

23.

Gene clustering based on RNAi phenotypes of ovary-enriched genes in C. elegans.

Piano F, Schetter AJ, Morton DG, Gunsalus KC, Reinke V, Kim SK, Kemphues KJ.

Curr Biol. 2002 Nov 19;12(22):1959-64.

24.

Integrating interactome, phenome, and transcriptome mapping data for the C. elegans germline.

Walhout AJ, Reboul J, Shtanko O, Bertin N, Vaglio P, Ge H, Lee H, Doucette-Stamm L, Gunsalus KC, Schetter AJ, Morton DG, Kemphues KJ, Reinke V, Kim SK, Piano F, Vidal M.

Curr Biol. 2002 Nov 19;12(22):1952-8.

25.

The 2001 Genetics Society of America Medal. H. Robert Horvitz.

Stenberg P, Kemphues K.

Genetics. 2002 Feb;160(2):369-70. No abstract available.

26.

The Caenorhabditis elegans par-5 gene encodes a 14-3-3 protein required for cellular asymmetry in the early embryo.

Morton DG, Shakes DC, Nugent S, Dichoso D, Wang W, Golden A, Kemphues KJ.

Dev Biol. 2002 Jan 1;241(1):47-58.

27.

The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo.

O'Connell KF, Caron C, Kopish KR, Hurd DD, Kemphues KJ, Li Y, White JG.

Cell. 2001 May 18;105(4):547-58.

28.

RNAi analysis of genes expressed in the ovary of Caenorhabditis elegans.

Piano F, Schetter AJ, Mangone M, Stein L, Kemphues KJ.

Curr Biol. 2000 Dec 14-28;10(24):1619-22.

29.

A Drosophila melanogaster homologue of Caenorhabditis elegans par-1 acts at an early step in embryonic-axis formation.

Tomancak P, Piano F, Riechmann V, Gunsalus KC, Kemphues KJ, Ephrussi A.

Nat Cell Biol. 2000 Jul;2(7):458-60. No abstract available.

PMID:
10878812
30.

PARsing embryonic polarity.

Kemphues K.

Cell. 2000 May 12;101(4):345-8. Review. No abstract available.

31.

The C. elegans par-4 gene encodes a putative serine-threonine kinase required for establishing embryonic asymmetry.

Watts JL, Morton DG, Bestman J, Kemphues KJ.

Development. 2000 Apr;127(7):1467-75.

32.
33.

Early patterning of the C. elegans embryo.

Rose LS, Kemphues KJ.

Annu Rev Genet. 1998;32:521-45. Review.

PMID:
9928490
34.
35.

An atypical PKC directly associates and colocalizes at the epithelial tight junction with ASIP, a mammalian homologue of Caenorhabditis elegans polarity protein PAR-3.

Izumi Y, Hirose T, Tamai Y, Hirai S, Nagashima Y, Fujimoto T, Tabuse Y, Kemphues KJ, Ohno S.

J Cell Biol. 1998 Oct 5;143(1):95-106.

36.

Atypical protein kinase C cooperates with PAR-3 to establish embryonic polarity in Caenorhabditis elegans.

Tabuse Y, Izumi Y, Piano F, Kemphues KJ, Miwa J, Ohno S.

Development. 1998 Sep;125(18):3607-14.

37.
38.
39.

par-6, a gene involved in the establishment of asymmetry in early C. elegans embryos, mediates the asymmetric localization of PAR-3.

Watts JL, Etemad-Moghadam B, Guo S, Boyd L, Draper BW, Mello CC, Priess JR, Kemphues KJ.

Development. 1996 Oct;122(10):3133-40.

40.

PAR-2 is asymmetrically distributed and promotes association of P granules and PAR-1 with the cortex in C. elegans embryos.

Boyd L, Guo S, Levitan D, Stinchcomb DT, Kemphues KJ.

Development. 1996 Oct;122(10):3075-84.

41.

Molecular genetics of asymmetric cleavage in the early Caenorhabditis elegans embryo.

Guo S, Kemphues KJ.

Curr Opin Genet Dev. 1996 Aug;6(4):408-15. Review.

PMID:
8791533
42.

A non-muscle myosin required for embryonic polarity in Caenorhabditis elegans.

Guo S, Kemphues KJ.

Nature. 1996 Aug 1;382(6590):455-8.

PMID:
8684486
43.
45.

Pseudocleavage is dispensable for polarity and development in C. elegans embryos.

Rose LS, Lamb ML, Hird SN, Kemphues KJ.

Dev Biol. 1995 Apr;168(2):479-89.

46.
47.

par-2, a gene required for blastomere asymmetry in Caenorhabditis elegans, encodes zinc-finger and ATP-binding motifs.

Levitan DJ, Boyd L, Mello CC, Kemphues KJ, Stinchcomb DT.

Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):6108-12.

49.

Mutations affecting the meiotic and mitotic divisions of the early Caenorhabditis elegans embryo.

Mains PE, Kemphues KJ, Sprunger SA, Sulston IA, Wood WB.

Genetics. 1990 Nov;126(3):593-605.

50.

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