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Items: 1 to 50 of 131

1.

Iron and atherosclerosis: too much of a good thing can be bad.

Kempf T, Wollert KC.

Eur Heart J. 2019 Jul 19. pii: ehz506. doi: 10.1093/eurheartj/ehz506. [Epub ahead of print] No abstract available.

PMID:
31324916
2.

Plasma Concentrations of Myeloid-Derived Growth Factor in Healthy Individuals and Patients with Acute Myocardial Infarction as Assessed by Multiple Reaction Monitoring-Mass Spectrometry.

Polten F, Reboll MR, Widera C, Kempf T, Bethmann K, Gupta P, Miglietta J, Pekcec A, Tillmanns J, Bauersachs J, Giannitsis E, Pich A, Wollert KC.

Anal Chem. 2019 Jan 15;91(2):1302-1308. doi: 10.1021/acs.analchem.8b03041. Epub 2018 Dec 28.

PMID:
30543396
3.

One-year outcomes with the HeartMate 3 left ventricular assist device.

Hanke JS, Dogan G, Zoch A, Ricklefs M, Wert L, Feldmann C, Bara C, Shrestha M, Tillmanns J, Kempf T, Bauersachs J, Haverich A, Schmitto JD.

J Thorac Cardiovasc Surg. 2018 Aug;156(2):662-669. doi: 10.1016/j.jtcvs.2018.01.083. Epub 2018 Feb 13.

PMID:
29525258
4.

microRNA-206 correlates with left ventricular function after transcatheter aortic valve implantation.

Kleeberger JA, Neuser J, de Gonzalo-Calvo D, Kempf T, Bauersachs J, Thum T, Widder JD.

Am J Physiol Heart Circ Physiol. 2017 Dec 1;313(6):H1261-H1266. doi: 10.1152/ajpheart.00432.2017. Epub 2017 Oct 13.

5.

Intermediate CD14++CD16+ monocytes decline after transcatheter aortic valve replacement and correlate with functional capacity and left ventricular systolic function.

Neuser J, Galuppo P, Fraccarollo D, Willig J, Kempf T, Berliner D, Bauersachs J, Widder JD.

PLoS One. 2017 Aug 22;12(8):e0183670. doi: 10.1371/journal.pone.0183670. eCollection 2017.

6.

[New pharmacologic therapies for chronic heart failure].

Kempf T, Bavendiek U, Bauersachs J.

Internist (Berl). 2017 Sep;58(9):990-999. doi: 10.1007/s00108-017-0277-1. Review. German.

PMID:
28653148
7.

Growth Differentiation Factor 15 as a Biomarker in Cardiovascular Disease.

Wollert KC, Kempf T, Wallentin L.

Clin Chem. 2017 Jan;63(1):140-151. doi: 10.1373/clinchem.2016.255174. Epub 2016 Oct 25. Review.

8.

Midregional proadrenomedullin and growth differentiation factor-15 are not influenced by obesity in heart failure patients.

Sinning C, Ojeda F, Wild PS, Schnabel RB, Schwarzl M, Ohdah S, Lackner KJ, Pfeiffer N, Michal M, Blettner M, Munzel T, Kempf T, Wollert KC, Kuulasmaa K, Blankenberg S, Salomaa V, Westermann D, Zeller T.

Clin Res Cardiol. 2017 Jun;106(6):401-410. doi: 10.1007/s00392-016-1066-x. Epub 2016 Dec 21.

PMID:
28004184
9.

Biomarkers for characterization of heart failure - Distinction of heart failure with preserved and reduced ejection fraction.

Sinning C, Kempf T, Schwarzl M, Lanfermann S, Ojeda F, Schnabel RB, Zengin E, Wild PS, Lackner KJ, Munzel T, Blankenberg S, Wollert KC, Zeller T, Westermann D.

Int J Cardiol. 2017 Jan 15;227:272-277. doi: 10.1016/j.ijcard.2016.11.110. Epub 2016 Nov 9.

PMID:
27838133
10.

Mid-term results of interventional closure of patent foramen ovale with the Occlutech Figulla® Flex II Occluder.

Neuser J, Akin M, Bavendiek U, Kempf T, Bauersachs J, Widder JD.

BMC Cardiovasc Disord. 2016 Nov 10;16(1):217.

11.

Early invasive versus non-invasive treatment in patients with non-ST-elevation acute coronary syndrome (FRISC-II): 15 year follow-up of a prospective, randomised, multicentre study.

Wallentin L, Lindhagen L, Ärnström E, Husted S, Janzon M, Johnsen SP, Kontny F, Kempf T, Levin LÅ, Lindahl B, Stridsberg M, Ståhle E, Venge P, Wollert KC, Swahn E, Lagerqvist B; FRISC-II study group.

Lancet. 2016 Oct 15;388(10054):1903-1911. doi: 10.1016/S0140-6736(16)31276-4. Epub 2016 Aug 29.

PMID:
27585757
12.

Identification of Novel Serum Autoantibodies for Differential Diagnosis of Autoimmune Pancreatitis and Pancreatic Ductal Adenocarcinoma.

Felix K, Hauck O, Schnölzer M, Kempf T, Warnken U, Schneider K, Bergmann F, Fritz S, Werner J.

Pancreas. 2016 Oct;45(9):1309-19. doi: 10.1097/MPA.0000000000000647.

PMID:
27623556
13.

Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure.

Haddad S, Wang Y, Galy B, Korf-Klingebiel M, Hirsch V, Baru AM, Rostami F, Reboll MR, Heineke J, Flögel U, Groos S, Renner A, Toischer K, Zimmermann F, Engeli S, Jordan J, Bauersachs J, Hentze MW, Wollert KC, Kempf T.

Eur Heart J. 2017 Feb 1;38(5):362-372. doi: 10.1093/eurheartj/ehw333.

PMID:
27545647
14.

Corrigendum: Myeloid-derived growth factor (C19orf10) mediates cardiac repair following myocardial infarction.

Korf-Klingebiel M, Reboll MR, Klede S, Brod T, Pich A, Polten F, Napp LC, Bauersachs J, Ganser A, Brinkmann E, Reimann I, Kempf T, Niessen HW, Mizrahi J, Schönfeld HJ, Iglesias A, Bobadilla M, Wang Y, Wollert KC.

Nat Med. 2016 Apr;22(4):446. doi: 10.1038/nm0416-446c. No abstract available.

PMID:
27050592
15.

Evaluation of Temporal Changes in Cardiovascular Biomarker Concentrations Improves Risk Prediction in an Elderly Population from the Community.

Eggers KM, Kempf T, Larsson A, Lindahl B, Venge P, Wallentin L, Wollert KC, Lind L.

Clin Chem. 2016 Mar;62(3):485-93. doi: 10.1373/clinchem.2015.246876. Epub 2016 Jan 14.

16.

Risk scores and biomarkers for the prediction of 1-year outcome after transcatheter aortic valve replacement.

Sinning JM, Wollert KC, Sedaghat A, Widera C, Radermacher MC, Descoups C, Hammerstingl C, Weber M, Stundl A, Ghanem A, Widder J, Vasa-Nicotera M, Mellert F, Schiller W, Bauersachs J, Zur B, Holdenrieder S, Welz A, Grube E, Pencina MJ, Nickenig G, Werner N, Kempf T.

Am Heart J. 2015 Oct;170(4):821-9. doi: 10.1016/j.ahj.2015.07.003. Epub 2015 Jul 10.

PMID:
26386807
17.

Myeloid-derived growth factor (C19orf10) mediates cardiac repair following myocardial infarction.

Korf-Klingebiel M, Reboll MR, Klede S, Brod T, Pich A, Polten F, Napp LC, Bauersachs J, Ganser A, Brinkmann E, Reimann I, Kempf T, Niessen HW, Mizrahi J, Schönfeld HJ, Iglesias A, Bobadilla M, Wang Y, Wollert KC.

Nat Med. 2015 Feb;21(2):140-9. doi: 10.1038/nm.3778. Epub 2015 Jan 12. Erratum in: Nat Med. 2016 Apr;22(4):446.

PMID:
25581518
18.

Single coronary artery anomaly with interarterial left main: caught inbetween.

Napp LC, Schatka I, Kempf T, Bavendiek U, Bengel FM, Bauersachs J.

Eur Heart J. 2015 Mar 21;36(12):762. doi: 10.1093/eurheartj/ehu495. Epub 2014 Dec 29. No abstract available.

PMID:
25549728
19.

Biomarkers of cardiovascular stress and subclinical atherosclerosis in the community.

Gopal DM, Larson MG, Januzzi JL, Cheng S, Ghorbani A, Wollert KC, Kempf T, D'Agostino RB, Polak JF, Ramachandran VS, Wang TJ, Ho JE.

Clin Chem. 2014 Nov;60(11):1402-8. doi: 10.1373/clinchem.2014.227116. Epub 2014 Sep 18.

20.

Growth-differentiation factor 15 for long-term prognostication in patients with non-ST-elevation acute coronary syndrome: an Invasive versus Conservative Treatment in Unstable coronary Syndromes (ICTUS) substudy.

Damman P, Kempf T, Windhausen F, van Straalen JP, Guba-Quint A, Fischer J, Tijssen JG, Wollert KC, de Winter RJ, Hirsch A; ICTUS investigators.

Int J Cardiol. 2014 Mar 15;172(2):356-63. doi: 10.1016/j.ijcard.2014.01.025. Epub 2014 Jan 23.

PMID:
24502880
21.

Drosophila Spag is the homolog of RNA polymerase II-associated protein 3 (RPAP3) and recruits the heat shock proteins 70 and 90 (Hsp70 and Hsp90) during the assembly of cellular machineries.

Benbahouche Nel H, Iliopoulos I, Török I, Marhold J, Henri J, Kajava AV, Farkaš R, Kempf T, Schnölzer M, Meyer P, Kiss I, Bertrand E, Mechler BM, Pradet-Balade B.

J Biol Chem. 2014 Feb 28;289(9):6236-47. doi: 10.1074/jbc.M113.499608. Epub 2014 Jan 6.

22.

mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy.

Weiler M, Blaes J, Pusch S, Sahm F, Czabanka M, Luger S, Bunse L, Solecki G, Eichwald V, Jugold M, Hodecker S, Osswald M, Meisner C, Hielscher T, Rübmann P, Pfenning PN, Ronellenfitsch M, Kempf T, Schnölzer M, Abdollahi A, Lang F, Bendszus M, von Deimling A, Winkler F, Weller M, Vajkoczy P, Platten M, Wick W.

Proc Natl Acad Sci U S A. 2014 Jan 7;111(1):409-14. doi: 10.1073/pnas.1314469111. Epub 2013 Dec 23.

23.

Serum protein signatures differentiating autoimmune pancreatitis versus pancreatic cancer.

Felix K, Hauck O, Fritz S, Hinz U, Schnölzer M, Kempf T, Warnken U, Michel A, Pawlita M, Werner J.

PLoS One. 2013 Dec 9;8(12):e82755. doi: 10.1371/journal.pone.0082755. eCollection 2013.

24.

Highly specific detection of myostatin prodomain by an immunoradiometric sandwich assay in serum of healthy individuals and patients.

Breitbart A, Scharf GM, Duncker D, Widera C, Gottlieb J, Vogel A, Schmidt S, Brandes G, Heuft HG, Lichtinghagen R, Kempf T, Wollert KC, Bauersachs J, Heineke J.

PLoS One. 2013 Nov 15;8(11):e80454. doi: 10.1371/journal.pone.0080454. eCollection 2013.

25.

Circulating concentrations of fibroblast activation protein α in apparently healthy individuals and patients with acute coronary syndrome as assessed by sandwich ELISA.

Tillmanns J, Widera C, Habbaba Y, Galuppo P, Kempf T, Wollert KC, Bauersachs J.

Int J Cardiol. 2013 Oct 9;168(4):3926-31. doi: 10.1016/j.ijcard.2013.06.061. Epub 2013 Aug 6.

PMID:
23932048
26.

Risk stratification in critically ill patients: GDF-15 scores in adult respiratory distress syndrome.

Kempf T, Wollert KC.

Crit Care. 2013 Jul 31;17(4):173. doi: 10.1186/cc12765.

27.

Biomarkers of cardiovascular stress and incident chronic kidney disease.

Ho JE, Hwang SJ, Wollert KC, Larson MG, Cheng S, Kempf T, Vasan RS, Januzzi JL, Wang TJ, Fox CS.

Clin Chem. 2013 Nov;59(11):1613-20. doi: 10.1373/clinchem.2013.205716. Epub 2013 Jul 19.

28.

Incremental prognostic value of biomarkers beyond the GRACE (Global Registry of Acute Coronary Events) score and high-sensitivity cardiac troponin T in non-ST-elevation acute coronary syndrome.

Widera C, Pencina MJ, Bobadilla M, Reimann I, Guba-Quint A, Marquardt I, Bethmann K, Korf-Klingebiel M, Kempf T, Lichtinghagen R, Katus HA, Giannitsis E, Wollert KC.

Clin Chem. 2013 Oct;59(10):1497-505. doi: 10.1373/clinchem.2013.206185. Epub 2013 Jul 1.

29.

In-depth mass spectrometric mapping of the human vitreous proteome.

Aretz S, Krohne TU, Kammerer K, Warnken U, Hotz-Wagenblatt A, Bergmann M, Stanzel BV, Kempf T, Holz FG, Schnölzer M, Kopitz J.

Proteome Sci. 2013 May 20;11(1):22. doi: 10.1186/1477-5956-11-22.

30.

Serum hepcidin levels and muscle iron proteins in humans injected with low- or high-dose erythropoietin.

Robach P, Recalcati S, Girelli D, Campostrini N, Kempf T, Wollert KC, Corbella M, Santambrogio P, Perbellini L, Brasse-Lagnel C, Christensen B, Moutereau S, Lundby C, Cairo G.

Eur J Haematol. 2013 Jul;91(1):74-84. doi: 10.1111/ejh.12122. Epub 2013 May 3.

PMID:
23582009
31.

Change in growth differentiation factor 15 concentrations over time independently predicts mortality in community-dwelling elderly individuals.

Eggers KM, Kempf T, Wallentin L, Wollert KC, Lind L.

Clin Chem. 2013 Jul;59(7):1091-8. doi: 10.1373/clinchem.2012.201210. Epub 2013 Mar 25.

32.

GDF-15 in heart failure: providing insight into end-organ dysfunction and its recovery?

Wollert KC, Kempf T.

Eur J Heart Fail. 2012 Nov;14(11):1191-3. doi: 10.1093/eurjhf/hfs158. Epub 2012 Oct 8. No abstract available.

33.

Clinical and genetic correlates of growth differentiation factor 15 in the community.

Ho JE, Mahajan A, Chen MH, Larson MG, McCabe EL, Ghorbani A, Cheng S, Johnson AD, Lindgren CM, Kempf T, Lind L, Ingelsson E, Vasan RS, Januzzi J, Wollert KC, Morris AP, Wang TJ.

Clin Chem. 2012 Nov;58(11):1582-91. doi: 10.1373/clinchem.2012.190322. Epub 2012 Sep 20.

34.

Growth differentiation factor 15 in heart failure: an update.

Wollert KC, Kempf T.

Curr Heart Fail Rep. 2012 Dec;9(4):337-45. doi: 10.1007/s11897-012-0113-9. Review.

PMID:
22961192
35.

Growth differentiation factor 15 predicts future insulin resistance and impaired glucose control in obese nondiabetic individuals: results from the XENDOS trial.

Kempf T, Guba-Quint A, Torgerson J, Magnone MC, Haefliger C, Bobadilla M, Wollert KC.

Eur J Endocrinol. 2012 Nov;167(5):671-8. doi: 10.1530/EJE-12-0466. Epub 2012 Aug 23.

PMID:
22918303
36.

Prognostic utility of novel biomarkers of cardiovascular stress: the Framingham Heart Study.

Wang TJ, Wollert KC, Larson MG, Coglianese E, McCabe EL, Cheng S, Ho JE, Fradley MG, Ghorbani A, Xanthakis V, Kempf T, Benjamin EJ, Levy D, Vasan RS, Januzzi JL.

Circulation. 2012 Sep 25;126(13):1596-604. Epub 2012 Aug 20.

37.

Identification of follistatin-like 1 by expression cloning as an activator of the growth differentiation factor 15 gene and a prognostic biomarker in acute coronary syndrome.

Widera C, Giannitsis E, Kempf T, Korf-Klingebiel M, Fiedler B, Sharma S, Katus HA, Asaumi Y, Shimano M, Walsh K, Wollert KC.

Clin Chem. 2012 Aug;58(8):1233-41. doi: 10.1373/clinchem.2012.182816. Epub 2012 Jun 6.

38.

Anti-inflammatory mechanisms and therapeutic opportunities in myocardial infarct healing.

Kempf T, Zarbock A, Vestweber D, Wollert KC.

J Mol Med (Berl). 2012 Apr;90(4):361-9. doi: 10.1007/s00109-011-0847-y. Epub 2012 Jan 7. Review.

PMID:
22228177
39.

Adjustment of the GRACE score by growth differentiation factor 15 enables a more accurate appreciation of risk in non-ST-elevation acute coronary syndrome.

Widera C, Pencina MJ, Meisner A, Kempf T, Bethmann K, Marquardt I, Katus HA, Giannitsis E, Wollert KC.

Eur Heart J. 2012 May;33(9):1095-104. doi: 10.1093/eurheartj/ehr444. Epub 2011 Dec 23.

40.

Leukocyte integrin activation and deactivation: novel mechanisms of balancing inflammation.

Zarbock A, Kempf T, Wollert KC, Vestweber D.

J Mol Med (Berl). 2012 Apr;90(4):353-9. doi: 10.1007/s00109-011-0835-2. Epub 2011 Nov 19. Review.

PMID:
22101734
41.

Costimulatory protein 4IgB7H3 drives the malignant phenotype of glioblastoma by mediating immune escape and invasiveness.

Lemke D, Pfenning PN, Sahm F, Klein AC, Kempf T, Warnken U, Schnölzer M, Tudoran R, Weller M, Platten M, Wick W.

Clin Cancer Res. 2012 Jan 1;18(1):105-17. doi: 10.1158/1078-0432.CCR-11-0880. Epub 2011 Nov 11.

42.

Transsignaling of interleukin-6 crucially contributes to atherosclerosis in mice.

Schuett H, Oestreich R, Waetzig GH, Annema W, Luchtefeld M, Hillmer A, Bavendiek U, von Felden J, Divchev D, Kempf T, Wollert KC, Seegert D, Rose-John S, Tietge UJ, Schieffer B, Grote K.

Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):281-90. doi: 10.1161/ATVBAHA.111.229435. Epub 2011 Nov 10.

PMID:
22075248
43.

Relations of growth-differentiation factor-15 to biomarkers reflecting vascular pathologies in a population-based sample of elderly subjects.

Eggers KM, Kempf T, Lind L, Sundström J, Wallentin L, Wollert KC, Siegbahn A.

Scand J Clin Lab Invest. 2012 Feb;72(1):45-51. doi: 10.3109/00365513.2011.626072. Epub 2011 Oct 24.

PMID:
22023041
44.

Diagnostic and prognostic impact of six circulating microRNAs in acute coronary syndrome.

Widera C, Gupta SK, Lorenzen JM, Bang C, Bauersachs J, Bethmann K, Kempf T, Wollert KC, Thum T.

J Mol Cell Cardiol. 2011 Nov;51(5):872-5. doi: 10.1016/j.yjmcc.2011.07.011. Epub 2011 Jul 23.

PMID:
21806992
45.

Elevated plasma growth differentiation factor-15 correlates with lymph node metastases and poor survival in endometrial cancer.

Staff AC, Trovik J, Eriksson AG, Wik E, Wollert KC, Kempf T, Salvesen HB.

Clin Cancer Res. 2011 Jul 15;17(14):4825-33. doi: 10.1158/1078-0432.CCR-11-0715. Epub 2011 May 26.

46.

Growth differentiation factor 15 plasma levels and outcome after ischemic stroke.

Worthmann H, Kempf T, Widera C, Tryc AB, Goldbecker A, Ma YT, Deb M, Tountopoulou A, Lambrecht J, Heeren M, Lichtinghagen R, Wollert KC, Weissenborn K.

Cerebrovasc Dis. 2011;32(1):72-8. doi: 10.1159/000328233. Epub 2011 May 25.

PMID:
21613788
47.

GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells.

Nickel N, Jonigk D, Kempf T, Bockmeyer CL, Maegel L, Rische J, Laenger F, Lehmann U, Sauer C, Greer M, Welte T, Hoeper MM, Golpon HA.

Respir Res. 2011 May 6;12:62. doi: 10.1186/1465-9921-12-62.

48.

GDF-15 is an inhibitor of leukocyte integrin activation required for survival after myocardial infarction in mice.

Kempf T, Zarbock A, Widera C, Butz S, Stadtmann A, Rossaint J, Bolomini-Vittori M, Korf-Klingebiel M, Napp LC, Hansen B, Kanwischer A, Bavendiek U, Beutel G, Hapke M, Sauer MG, Laudanna C, Hogg N, Vestweber D, Wollert KC.

Nat Med. 2011 May;17(5):581-8. doi: 10.1038/nm.2354. Epub 2011 Apr 24.

PMID:
21516086
49.

A simple non-invasive diagnostic algorithm for ruling out chronic thromboembolic pulmonary hypertension in patients after acute pulmonary embolism.

Klok FA, Surie S, Kempf T, Eikenboom J, van Straalen JP, van Kralingen KW, van Dijk AP, Vliegen HW, Bresser P, Wollert KC, Huisman MV.

Thromb Res. 2011 Jul;128(1):21-6. doi: 10.1016/j.thromres.2011.03.004. Epub 2011 Mar 30.

50.

Expression and clinical role of growth differentiation factor-15 in ovarian carcinoma effusions.

Bock AJ, Stavnes HT, Kempf T, Tropè CG, Berner A, Davidson B, Staff AC.

Int J Gynecol Cancer. 2010 Dec;20(9):1448-55. doi: 10.1111/IGC.0b013e3181f7d6be. Erratum in: Int J Gynecol Cancer. 2013 Feb;23(2):399.

PMID:
21336029

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