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Items: 26

1.

Extending (Q)SARs to incorporate proprietary knowledge for regulatory purposes: A case study using aromatic amine mutagenicity.

Ahlberg E, Amberg A, Beilke LD, Bower D, Cross KP, Custer L, Ford KA, Van Gompel J, Harvey J, Honma M, Jolly R, Joossens E, Kemper RA, Kenyon M, Kruhlak N, Kuhnke L, Leavitt P, Naven R, Neilan C, Quigley DP, Shuey D, Spirkl HP, Stavitskaya L, Teasdale A, White A, Wichard J, Zwickl C, Myatt GJ.

Regul Toxicol Pharmacol. 2016 Jun;77:1-12. doi: 10.1016/j.yrtph.2016.02.003. Epub 2016 Feb 13.

PMID:
26879463
2.

Late-stage optimization of a tercyclic class of S1P3-sparing, S1P1 receptor agonists.

Horan JC, Kuzmich D, Liu P, DiSalvo D, Lord J, Mao C, Hopkins TD, Yu H, Harcken C, Betageri R, Hill-Drzewi M, Patenaude L, Patel M, Fletcher K, Terenzzio D, Linehan B, Xia H, Patel M, Studwell D, Miller C, Hickey E, Levin JI, Smith D, Kemper RA, Modis LK, Bannen LC, Chan DS, Mac MB, Ng S, Wang Y, Xu W, Lemieux RM.

Bioorg Med Chem Lett. 2016 Jan 15;26(2):466-471. doi: 10.1016/j.bmcl.2015.11.090. Epub 2015 Nov 26.

PMID:
26687487
3.

Bacterial mutagenicity screening in the pharmaceutical industry.

Escobar PA, Kemper RA, Tarca J, Nicolette J, Kenyon M, Glowienke S, Sawant SG, Christensen J, Johnson TE, McKnight C, Ward G, Galloway SM, Custer L, Gocke E, O'Donovan MR, Braun K, Snyder RD, Mahadevan B.

Mutat Res. 2013 Apr-Jun;752(2):99-118. doi: 10.1016/j.mrrev.2012.12.002. Epub 2012 Dec 20. Review. Erratum in: Mutat Res. 2013 Oct-Dec;753(2):155.

PMID:
23262374
4.

Genetic toxicology in the 21st century: reflections and future directions.

Mahadevan B, Snyder RD, Waters MD, Benz RD, Kemper RA, Tice RR, Richard AM.

Environ Mol Mutagen. 2011 Jun;52(5):339-54. doi: 10.1002/em.20653. Epub 2011 Apr 28. Review.

5.

An in silico method for predicting Ames activities of primary aromatic amines by calculating the stabilities of nitrenium ions.

Bentzien J, Hickey ER, Kemper RA, Brewer ML, Dyekjaer JD, East SP, Whittaker M.

J Chem Inf Model. 2010 Feb 22;50(2):274-97. doi: 10.1021/ci900378x.

PMID:
20078034
6.

Evaluation of respiratory parameters in rats and rabbits exposed to methyl iodide.

DeLorme MP, Himmelstein MW, Kemper RA, Kegelman TA, Gargas ML, Kinzell JH.

Inhal Toxicol. 2009 May;21(6):505-11. doi: 10.1080/08958370802596926.

PMID:
19519150
7.

Two-day inhalation toxicity study of methyl iodide in the rat.

Himmelstein MW, Kegelman TA, DeLorme MP, Everds NE, O'Connor JC, Kemper RA, Nabb DL, Mileson BE, Bevan C.

Inhal Toxicol. 2009 May;21(6):480-7. doi: 10.1080/08958370802596892.

PMID:
19519148
8.

Understanding genetic toxicity through data mining: the process of building knowledge by integrating multiple genetic toxicity databases.

Yang C, Hasselgren CH, Boyer S, Arvidson K, Aveston S, Dierkes P, Benigni R, Benz RD, Contrera J, Kruhlak NL, Matthews EJ, Han X, Jaworska J, Kemper RA, Rathman JF, Richard AM.

Toxicol Mech Methods. 2008;18(2-3):277-95. doi: 10.1080/15376510701857502.

PMID:
20020921
9.

Absorption, distribution, metabolism, and elimination of 8-2 fluorotelomer alcohol in the rat.

Fasano WJ, Carpenter SC, Gannon SA, Snow TA, Stadler JC, Kennedy GL, Buck RC, Korzeniowski SH, Hinderliter PM, Kemper RA.

Toxicol Sci. 2006 Jun;91(2):341-55. Epub 2006 Mar 16. Erratum in: Toxicol Sci. 2008 Apr;102(2):455.

PMID:
16543293
10.

Comparative metabolism of geranyl nitrile and citronellyl nitrile in mouse, rat, and human hepatocytes.

Kemper RA, Nabb DL, Gannon SA, Snow TA, Api AM.

Drug Metab Dispos. 2006 Jun;34(6):1019-29. Epub 2006 Mar 15.

PMID:
16540590
12.

Subcellular distribution and protein binding of perfluorooctanoic acid in rat liver and kidney.

Han X, Kemper RA, Jepson GW.

Drug Chem Toxicol. 2005;28(2):197-209.

PMID:
15865261
13.

Binding of perfluorooctanoic acid to rat and human plasma proteins.

Han X, Snow TA, Kemper RA, Jepson GW.

Chem Res Toxicol. 2003 Jun;16(6):775-81.

PMID:
12807361
14.

Reactive metabolites of 1,3-butadiene: DNA and hemoglobin adduct formation and potential roles in carcinogenicity.

Elfarra AA, Moll TS, Krause RJ, Kemper RA, Selzer RR.

Adv Exp Med Biol. 2001;500:93-103. Review. No abstract available.

PMID:
11765021
16.

Cellular and molecular basis for species, sex and tissue differences in 1,3-butadiene metabolism.

Elfarra AA, Krause RJ, Kemper RA.

Chem Biol Interact. 2001 Jun 1;135-136:239-48.

PMID:
11397394
18.
19.

Oxidation of 3-butene-1,2-diol by alcohol dehydrogenase.

Kemper RA, Elfarra AA.

Chem Res Toxicol. 1996 Oct-Nov;9(7):1127-34.

PMID:
8902267
20.
21.

Studies on inhibition and induction of metabolism of ethyl carbamate by acetone and related compounds. Evidence for metabolism by cytochromes P-450.

Kurata N, Hurst HE, Benz FW, Kemper RA, Waddell WJ.

Drug Metab Dispos. 1991 Mar-Apr;19(2):388-93.

PMID:
1676642
22.

Studies on induction of metabolism of ethyl carbamate in mice by ethanol.

Kurata N, Hurst HE, Kemper RA, Waddell WJ.

Drug Metab Dispos. 1991 Jan-Feb;19(1):239-40.

PMID:
1673406
23.

Measurement of ethyl carbamate in blood by capillary gas chromatography/mass spectrometry using selected ion monitoring.

Hurst HE, Kemper RA, Kurata N.

Biomed Environ Mass Spectrom. 1990 Jan;19(1):27-31.

PMID:
2306547
24.

Karl w. Ascher 1887-1971.

Kemper RA.

Am J Ophthalmol. 1972 Jan;73(1):140. No abstract available.

PMID:
4550198
25.

Outflow of aqueous humor; biomicroscopic estimation compared with tonographic measurement.

STEPANIK J, KEMPER RA.

AMA Arch Ophthalmol. 1954 May;51(5):671-80. No abstract available.

PMID:
13147620
26.

Normative data obtained in the house-to-house administration of a psychosomatic inventory.

THORNDIKE RL, HAGEN E, KEMPER RA.

J Consult Psychol. 1952 Aug;16(4):257-60. No abstract available.

PMID:
12990708

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