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Items: 11

1.

An open-label, randomized, single-center, two-period, phase I, crossover study of the effect of zibotentan (ZD4054) on the pharmacokinetics of midazolam in healthy male volunteers.

Tomkinson HK, Kemp JV, Wollseifen T, Morris T, Oliver SD.

Clin Ther. 2010 Jul;32(7):1372-86. doi: 10.1016/j.clinthera.2010.07.013.

PMID:
20678684
2.

Minimal contribution of desmethyl-gefitinib, the major human plasma metabolite of gefitinib, to epidermal growth factor receptor (EGFR)-mediated tumour growth inhibition.

McKillop D, Guy SP, Spence MP, Kendrew J, Kemp JV, Bushby N, Wood PG, Barnett S, Hutchison M.

Xenobiotica. 2006 Jan;36(1):29-39.

PMID:
16507511
3.

Tumor penetration of gefitinib (Iressa), an epidermal growth factor receptor tyrosine kinase inhibitor.

McKillop D, Partridge EA, Kemp JV, Spence MP, Kendrew J, Barnett S, Wood PG, Giles PB, Patterson AB, Bichat F, Guilbaud N, Stephens TC.

Mol Cancer Ther. 2005 Apr;4(4):641-9.

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The effect of aldose reductase inhibition on erythrocyte polyols and galactitol accumulation in diabetic patients.

Airey CM, Price DE, Kemp JV, Perkins CM, Wales JK.

Diabet Med. 1989 Dec;6(9):804-8.

PMID:
2533041
7.

Identification and biological activity of tamoxifen metabolites in human serum.

Kemp JV, Adam HK, Wakeling AE, Slater R.

Biochem Pharmacol. 1983 Jul 1;32(13):2045-52.

PMID:
6870933
8.

Tamoxifen (Nolvadex) therapy--radionale for loading dose followed by maintenance dose for patients with metastatic breast cancer.

Wilkinson PM, Ribiero GG, Adam HK, Kemp JV, Patterson JS.

Cancer Chemother Pharmacol. 1982 Dec;10(1):33-5. No abstract available.

PMID:
7160042
9.

Studies on the metabolism and pharmacokinetics of tamoxifen in normal volunteers.

Adam HK, Patterson JS, Kemp JV.

Cancer Treat Rep. 1980 Jun-Jul;64(6-7):761-4.

PMID:
7427960
10.

Serum concentrations of tamoxifen and major metabolite during long-term nolvadex therapy, correlated with clinical response.

Patterson JS, Settatree RS, Adam HK, Kemp JV.

Eur J Cancer. 1980;Suppl 1:89-92. No abstract available.

PMID:
7318875
11.

The metabolism of tamoxifen in human.

Adam HK, Douglas EJ, Kemp JV.

Biochem Pharmacol. 1979;28(1):145-7. No abstract available.

PMID:
758904

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