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Items: 20


Iroquois homeobox 2 suppresses cellular motility and chemokine expression in breast cancer cells.

Werner S, Stamm H, Pandjaitan M, Kemming D, Brors B, Pantel K, Wikman H.

BMC Cancer. 2015 Nov 11;15:896. doi: 10.1186/s12885-015-1907-4.


Suppression of early hematogenous dissemination of human breast cancer cells to bone marrow by retinoic Acid-induced 2.

Werner S, Brors B, Eick J, Marques E, Pogenberg V, Parret A, Kemming D, Wood AW, Edgren H, Neubauer H, Streichert T, Riethdorf S, Bedi U, Baccelli I, Jücker M, Eils R, Fehm T, Trumpp A, Johnsen SA, Klefström J, Wilmanns M, Müller V, Pantel K, Wikman H.

Cancer Discov. 2015 May;5(5):506-19. doi: 10.1158/2159-8290.CD-14-1042. Epub 2015 Feb 25.


Identification of HERC5 and its potential role in NSCLC progression.

Wrage M, Hagmann W, Kemming D, Uzunoglu FG, Riethdorf S, Effenberger K, Westphal M, Lamszus K, Kim SZ, Becker N, Izbicki JR, Sandoval J, Esteller M, Pantel K, Risch A, Wikman H.

Int J Cancer. 2015 May 15;136(10):2264-72. doi: 10.1002/ijc.29298. Epub 2014 Nov 9.


Loss of CADM1 expression is associated with poor prognosis and brain metastasis in breast cancer patients.

Wikman H, Westphal L, Schmid F, Pollari S, Kropidlowski J, Sielaff-Frimpong B, Glatzel M, Matschke J, Westphal M, Iljin K, Huhtala H, Terracciano L, Kallioniemi A, Sauter G, Müller V, Witzel I, Lamszus K, Kemming D, Pantel K.

Oncotarget. 2014 May 30;5(10):3076-87.


MMP7 is a target of the tumour-associated antigen EpCAM.

Denzel S, Mack B, Eggert C, Massoner P, Stöcklein N, Kemming D, Harréus U, Gires O.

Int J Exp Pathol. 2012 Oct;93(5):341-53. doi: 10.1111/j.1365-2613.2012.00826.x.


Relevance of PTEN loss in brain metastasis formation in breast cancer patients.

Wikman H, Lamszus K, Detels N, Uslar L, Wrage M, Benner C, Hohensee I, Ylstra B, Eylmann K, Zapatka M, Sauter G, Kemming D, Glatzel M, Müller V, Westphal M, Pantel K.

Breast Cancer Res. 2012 Mar 19;14(2):R49.


Quantitative high-resolution genomic analysis of single cancer cells.

Hannemann J, Meyer-Staeckling S, Kemming D, Alpers I, Joosse SA, Pospisil H, Kurtz S, Görndt J, Püschel K, Riethdorf S, Pantel K, Brandt B.

PLoS One. 2011;6(11):e26362. doi: 10.1371/journal.pone.0026362. Epub 2011 Nov 30.


A distinct subset of glioma cell lines with stem cell-like properties reflects the transcriptional phenotype of glioblastomas and overexpresses CXCR4 as therapeutic target.

Schulte A, Günther HS, Phillips HS, Kemming D, Martens T, Kharbanda S, Soriano RH, Modrusan Z, Zapf S, Westphal M, Lamszus K.

Glia. 2011 Apr;59(4):590-602. doi: 10.1002/glia.21127. Epub 2011 Feb 3.


TOB1 is regulated by EGF-dependent HER2 and EGFR signaling, is highly phosphorylated, and indicates poor prognosis in node-negative breast cancer.

Helms MW, Kemming D, Contag CH, Pospisil H, Bartkowiak K, Wang A, Chang SY, Buerger H, Brandt BH.

Cancer Res. 2009 Jun 15;69(12):5049-56. doi: 10.1158/0008-5472.CAN-08-4154. Epub 2009 Jun 2.


Inhibition of glioblastoma growth in a highly invasive nude mouse model can be achieved by targeting epidermal growth factor receptor but not vascular endothelial growth factor receptor-2.

Martens T, Laabs Y, Günther HS, Kemming D, Zhu Z, Witte L, Hagel C, Westphal M, Lamszus K.

Clin Cancer Res. 2008 Sep 1;14(17):5447-58. doi: 10.1158/1078-0432.CCR-08-0147.


Squalene epoxidase, located on chromosome 8q24.1, is upregulated in 8q+ breast cancer and indicates poor clinical outcome in stage I and II disease.

Helms MW, Kemming D, Pospisil H, Vogt U, Buerger H, Korsching E, Liedtke C, Schlotter CM, Wang A, Chan SY, Brandt BH.

Br J Cancer. 2008 Sep 2;99(5):774-80. doi: 10.1038/sj.bjc.6604556. Epub 2008 Aug 12.


Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria.

Günther HS, Schmidt NO, Phillips HS, Kemming D, Kharbanda S, Soriano R, Modrusan Z, Meissner H, Westphal M, Lamszus K.

Oncogene. 2008 May 1;27(20):2897-909. Epub 2007 Nov 26.


[Expression of early placenta insulin-like growth factor (EPIL) in breast cancer cells provides an autocrine loop with enhancement of predominantly HER-2-related invasivity].

Bürger H, Kemming D, Helms M, Feldmann U, Matuschek A, Böcker W, Brandt B.

Verh Dtsch Ges Pathol. 2005;89:201-6. German.


Whole genome expression analysis for biologic rational pathway modeling: application in cancer prognosis and therapy prediction.

Kemming D, Vogt U, Tidow N, Schlotter CM, Bürger H, Helms MW, Korsching E, Granetzny A, Boseila A, Hillejan L, Marra A, Ergönenc Y, Adigüzel H, Brandt B.

Mol Diagn Ther. 2006;10(5):271-80. Review.


Expression of early placenta insulin-like growth factor in breast cancer cells provides an autocrine loop that predominantly enhances invasiveness and motility.

Brandt B, Kemming D, Packeisen J, Simon R, Helms M, Feldmann U, Matuschek A, Kersting C, Hinrichs B, Bidart JM, Bellet D, Bartkowiak K, Dankbar N, Dittmar T, Sauter G, Boecker W, Buerger H.

Endocr Relat Cancer. 2005 Dec;12(4):823-37.


3D-extravasation model -- selection of highly motile and metastatic cancer cells.

Brandt B, Heyder C, Gloria-Maercker E, Hatzmann W, Rötger A, Kemming D, Zänker KS, Entschladen F, Dittmar T.

Semin Cancer Biol. 2005 Oct;15(5):387-95. Review.


Up-regulation of gene expression by hypoxia is mediated predominantly by hypoxia-inducible factor 1 (HIF-1).

Greijer AE, van der Groep P, Kemming D, Shvarts A, Semenza GL, Meijer GA, van de Wiel MA, Belien JA, van Diest PJ, van der Wall E.

J Pathol. 2005 Jul;206(3):291-304.


Selective expression of a splice variant of decay-accelerating factor in c-erbB-2-positive mammary carcinoma cells showing increased transendothelial invasiveness.

Brandt B, Mikesch JH, Simon R, Rötger A, Kemming D, Schier K, Sauter G, Bürger H.

Biochem Biophys Res Commun. 2005 Apr 1;329(1):318-23.


Early placenta insulin-like growth factor (pro-EPIL) is overexpressed and secreted by c-erbB-2-positive cells with high invasion potential.

Brandt B, Roetger A, Bidart JM, Packeisen J, Schier K, Mikesch JH, Kemming D, Boecker W, Yu D, Buerger H.

Cancer Res. 2002 Feb 15;62(4):1020-4.

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