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The genetic landscape of Arab Population, Chechens and Circassians subpopulations from Jordan through HV1 and HV2 regions of mtDNA.

Al-Eitan L, Saadeh H, Alnaamneh A, Darabseh S, Al-Sarhan N, Alzihlif M, Hakooz N, Ivanova E, Kelsey G, Dajani R.

Gene. 2020 Mar 1;729:144314. doi: 10.1016/j.gene.2019.144314. Epub 2019 Dec 26.


Genome-wide assessment of DNA methylation in mouse oocytes reveals effects associated with in vitro growth, superovulation, and sexual maturity.

Saenz-de-Juano MD, Ivanova E, Billooye K, Herta AC, Smitz J, Kelsey G, Anckaert E.

Clin Epigenetics. 2019 Dec 19;11(1):197. doi: 10.1186/s13148-019-0794-y.


A KHDC3L mutation resulting in recurrent hydatidiform mole causes genome-wide DNA methylation loss in oocytes and persistent imprinting defects post-fertilisation.

Demond H, Anvar Z, Jahromi BN, Sparago A, Verma A, Davari M, Calzari L, Russo S, Jahromi MA, Monk D, Andrews S, Riccio A, Kelsey G.

Genome Med. 2019 Dec 17;11(1):84. doi: 10.1186/s13073-019-0694-y.


Multi-omics profiling of mouse gastrulation at single-cell resolution.

Argelaguet R, Clark SJ, Mohammed H, Stapel LC, Krueger C, Kapourani CA, Imaz-Rosshandler I, Lohoff T, Xiang Y, Hanna CW, Smallwood S, Ibarra-Soria X, Buettner F, Sanguinetti G, Xie W, Krueger F, Göttgens B, Rugg-Gunn PJ, Kelsey G, Dean W, Nichols J, Stegle O, Marioni JC, Reik W.

Nature. 2019 Dec;576(7787):487-491. doi: 10.1038/s41586-019-1825-8. Epub 2019 Dec 11.


The role and mechanisms of DNA methylation in the oocyte.

Sendžikaitė G, Kelsey G.

Essays Biochem. 2019 Dec 20;63(6):691-705. doi: 10.1042/EBC20190043.


Anti-Xa levels with low molecular weight heparin calibrator can be used to exclude significant apixaban effect.

Singh J, Ong DM, Wallis A, Kelsey G, Tran H.

Pathology. 2019 Dec;51(7):768-769. doi: 10.1016/j.pathol.2019.07.012. Epub 2019 Oct 30. No abstract available.


Endogenous retroviral insertions drive non-canonical imprinting in extra-embryonic tissues.

Hanna CW, Pérez-Palacios R, Gahurova L, Schubert M, Krueger F, Biggins L, Andrews S, Colomé-Tatché M, Bourc'his D, Dean W, Kelsey G.

Genome Biol. 2019 Oct 29;20(1):225. doi: 10.1186/s13059-019-1833-x.


DNA methylation and mRNA expression of imprinted genes in blastocysts derived from an improved in vitro maturation method for oocytes from small antral follicles in polycystic ovary syndrome patients.

Saenz-de-Juano MD, Ivanova E, Romero S, Lolicato F, Sánchez F, Van Ranst H, Krueger F, Segonds-Pichon A, De Vos M, Andrews S, Smitz J, Kelsey G, Anckaert E.

Hum Reprod. 2019 Sep 29;34(9):1640-1649. doi: 10.1093/humrep/dez121.


Interlaboratory validation of apixaban levels in ex vivo patient samples using a chromogenic anti-factor Xa assay.

Singh J, Ong DM, Ling V, Lim MS, Malan E, Servadei P, Wallis A, Kelsey G, Chunilal S, Tran H.

Int J Lab Hematol. 2020 Feb;42(1):e23-e26. doi: 10.1111/ijlh.13081. Epub 2019 Jul 9. No abstract available.


A DNMT3A PWWP mutation leads to methylation of bivalent chromatin and growth retardation in mice.

Sendžikaitė G, Hanna CW, Stewart-Morgan KR, Ivanova E, Kelsey G.

Nat Commun. 2019 Apr 23;10(1):1884. doi: 10.1038/s41467-019-09713-w.


Genomic Imprinting and Physiological Processes in Mammals.

Tucci V, Isles AR, Kelsey G, Ferguson-Smith AC; Erice Imprinting Group.

Cell. 2019 Feb 21;176(5):952-965. doi: 10.1016/j.cell.2019.01.043. Review.


Genome-Scale Oscillations in DNA Methylation during Exit from Pluripotency.

Rulands S, Lee HJ, Clark SJ, Angermueller C, Smallwood SA, Krueger F, Mohammed H, Dean W, Nichols J, Rugg-Gunn P, Kelsey G, Stegle O, Simons BD, Reik W.

Cell Syst. 2018 Jul 25;7(1):63-76.e12. doi: 10.1016/j.cels.2018.06.012.


Epigenetic regulation in development: is the mouse a good model for the human?

Hanna CW, Demond H, Kelsey G.

Hum Reprod Update. 2018 Sep 1;24(5):556-576. doi: 10.1093/humupd/dmy021. Review.


scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells.

Clark SJ, Argelaguet R, Kapourani CA, Stubbs TM, Lee HJ, Alda-Catalinas C, Krueger F, Sanguinetti G, Kelsey G, Marioni JC, Stegle O, Reik W.

Nat Commun. 2018 Feb 22;9(1):781. doi: 10.1038/s41467-018-03149-4.


MLL2 conveys transcription-independent H3K4 trimethylation in oocytes.

Hanna CW, Taudt A, Huang J, Gahurova L, Kranz A, Andrews S, Dean W, Stewart AF, Colomé-Tatché M, Kelsey G.

Nat Struct Mol Biol. 2018 Jan;25(1):73-82. doi: 10.1038/s41594-017-0013-5. Epub 2018 Jan 1.


Cultured bovine embryo biopsy conserves methylation marks from original embryo.

Fonseca Balvís N, Garcia-Martinez S, Pérez-Cerezales S, Ivanova E, Gomez-Redondo I, Hamdi M, Rizos D, Coy P, Kelsey G, Gutierrez-Adan A.

Biol Reprod. 2017 Aug 1;97(2):189-196. doi: 10.1093/biolre/iox077.


Single-cell epigenomics: Recording the past and predicting the future.

Kelsey G, Stegle O, Reik W.

Science. 2017 Oct 6;358(6359):69-75. doi: 10.1126/science.aan6826. Review.


DNA Methylation in Embryo Development: Epigenetic Impact of ART (Assisted Reproductive Technologies).

Canovas S, Ross PJ, Kelsey G, Coy P.

Bioessays. 2017 Nov;39(11). doi: 10.1002/bies.201700106. Epub 2017 Sep 21. Review.


Genomic imprinting beyond DNA methylation: a role for maternal histones.

Hanna CW, Kelsey G.

Genome Biol. 2017 Sep 19;18(1):177. doi: 10.1186/s13059-017-1317-9. Review.


Setd1b, encoding a histone 3 lysine 4 methyltransferase, is a maternal effect gene required for the oogenic gene expression program.

Brici D, Zhang Q, Reinhardt S, Dahl A, Hartmann H, Schmidt K, Goveas N, Huang J, Gahurova L, Kelsey G, Anastassiadis K, Stewart AF, Kranz A.

Development. 2017 Jul 15;144(14):2606-2617. doi: 10.1242/dev.143347. Epub 2017 Jun 15.


Transcription and chromatin determinants of de novo DNA methylation timing in oocytes.

Gahurova L, Tomizawa SI, Smallwood SA, Stewart-Morgan KR, Saadeh H, Kim J, Andrews SR, Chen T, Kelsey G.

Epigenetics Chromatin. 2017 May 12;10:25. doi: 10.1186/s13072-017-0133-5. eCollection 2017.


Genome-wide base-resolution mapping of DNA methylation in single cells using single-cell bisulfite sequencing (scBS-seq).

Clark SJ, Smallwood SA, Lee HJ, Krueger F, Reik W, Kelsey G.

Nat Protoc. 2017 Mar;12(3):534-547. doi: 10.1038/nprot.2016.187. Epub 2017 Feb 9.


DNA methylation and gene expression changes derived from assisted reproductive technologies can be decreased by reproductive fluids.

Canovas S, Ivanova E, Romar R, García-Martínez S, Soriano-Úbeda C, García-Vázquez FA, Saadeh H, Andrews S, Kelsey G, Coy P.

Elife. 2017 Feb 1;6. pii: e23670. doi: 10.7554/eLife.23670.


Establishment and functions of DNA methylation in the germline.

Stewart KR, Veselovska L, Kelsey G.

Epigenomics. 2016 Oct;8(10):1399-1413. Epub 2016 Sep 23. Review.


Single-cell epigenomics: powerful new methods for understanding gene regulation and cell identity.

Clark SJ, Lee HJ, Smallwood SA, Kelsey G, Reik W.

Genome Biol. 2016 Apr 18;17:72. doi: 10.1186/s13059-016-0944-x. Review.


Pervasive polymorphic imprinted methylation in the human placenta.

Hanna CW, Peñaherrera MS, Saadeh H, Andrews S, McFadden DE, Kelsey G, Robinson WP.

Genome Res. 2016 Jun;26(6):756-67. doi: 10.1101/gr.196139.115. Epub 2016 Jan 14.


Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity.

Angermueller C, Clark SJ, Lee HJ, Macaulay IC, Teng MJ, Hu TX, Krueger F, Smallwood S, Ponting CP, Voet T, Kelsey G, Stegle O, Reik W.

Nat Methods. 2016 Mar;13(3):229-232. doi: 10.1038/nmeth.3728. Epub 2016 Jan 11.


Erratum to: Deep sequencing and de novo assembly of the mouse occyte transcriptome define the contribution of transcription to the DNA methylation landscape.

Veselovska L, Smallwood SA, Saadeh H, Stewart KR, Krueger F, Maupetit-Méhouas S, Arnaud P, Tomizawa S, Andrews S, Kelsey G.

Genome Biol. 2015 Dec 3;16:271. doi: 10.1186/s13059-015-0809-8. No abstract available.


Antisense Activity across the Nesp Promoter is Required for Nespas-Mediated Silencing in the Imprinted Gnas Cluster.

Tibbit CJ, Williamson CM, Mehta S, Ball ST, Chotalia M, Nottingham WT, Eaton SA, Quwailid MM, Teboul L, Kelsey G, Peters J.

Noncoding RNA. 2015 Nov 30;1(3):246-265. doi: 10.3390/ncrna1030246.


Dynamic changes in histone modifications precede de novo DNA methylation in oocytes.

Stewart KR, Veselovska L, Kim J, Huang J, Saadeh H, Tomizawa S, Smallwood SA, Chen T, Kelsey G.

Genes Dev. 2015 Dec 1;29(23):2449-62. doi: 10.1101/gad.271353.115. Epub 2015 Nov 19.


Continuous Histone Replacement by Hira Is Essential for Normal Transcriptional Regulation and De Novo DNA Methylation during Mouse Oogenesis.

Nashun B, Hill PW, Smallwood SA, Dharmalingam G, Amouroux R, Clark SJ, Sharma V, Ndjetehe E, Pelczar P, Festenstein RJ, Kelsey G, Hajkova P.

Mol Cell. 2015 Nov 19;60(4):611-25. doi: 10.1016/j.molcel.2015.10.010. Epub 2015 Nov 5.


Deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the DNA methylation landscape.

Veselovska L, Smallwood SA, Saadeh H, Stewart KR, Krueger F, Maupetit-Méhouas S, Arnaud P, Tomizawa S, Andrews S, Kelsey G.

Genome Biol. 2015 Sep 25;16:209. doi: 10.1186/s13059-015-0769-z. Erratum in: Genome Biol. 2015;16:271.


Keeping methylation at bay.

Kelsey G.

Nat Genet. 2015 May;47(5):427-8. doi: 10.1038/ng.3290.


Epigenetics: Cellular memory erased in human embryos.

Reik W, Kelsey G.

Nature. 2014 Jul 31;511(7511):540-1. doi: 10.1038/nature13648. Epub 2014 Jul 23. No abstract available.


Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity.

Smallwood SA, Lee HJ, Angermueller C, Krueger F, Saadeh H, Peat J, Andrews SR, Stegle O, Reik W, Kelsey G.

Nat Methods. 2014 Aug;11(8):817-820. doi: 10.1038/nmeth.3035. Epub 2014 Jul 20.


The specification of imprints in mammals.

Hanna CW, Kelsey G.

Heredity (Edinb). 2014 Aug;113(2):176-83. doi: 10.1038/hdy.2014.54. Epub 2014 Jun 18. Review.


Detailed analysis of the genetic and epigenetic signatures of iPSC-derived mesodiencephalic dopaminergic neurons.

Roessler R, Smallwood SA, Veenvliet JV, Pechlivanoglou P, Peng SP, Chakrabarty K, Groot-Koerkamp MJ, Pasterkamp RJ, Wesseling E, Kelsey G, Boddeke E, Smidt MP, Copray S.

Stem Cell Reports. 2014 Apr 3;2(4):520-33. doi: 10.1016/j.stemcr.2014.03.001. eCollection 2014 Apr 8.


DNA methylation establishment during oocyte growth: mechanisms and significance.

Tomizawa S, Nowacka-Woszuk J, Kelsey G.

Int J Dev Biol. 2012;56(10-12):867-75. doi: 10.1387/ijdb.120152gk. Review.


Disseminated toxoplasmosis after allogeneic stem cell transplantation in a seronegative recipient.

Osthoff M, Chew E, Bajel A, Kelsey G, Panek-Hudson Y, Mason K, Szer J, Ritchie D, Slavin M.

Transpl Infect Dis. 2013 Feb;15(1):E14-9. doi: 10.1111/tid.12043. Epub 2012 Dec 20.


New insights into establishment and maintenance of DNA methylation imprints in mammals.

Kelsey G, Feil R.

Philos Trans R Soc Lond B Biol Sci. 2013 Jan 5;368(1609):20110336. doi: 10.1098/rstb.2011.0336. Review.


DNA methylation at differentially methylated regions of imprinted genes is resistant to developmental programming by maternal nutrition.

Ivanova E, Chen JH, Segonds-Pichon A, Ozanne SE, Kelsey G.

Epigenetics. 2012 Oct;7(10):1200-10. doi: 10.4161/epi.22141. Epub 2012 Sep 11.


Genome-wide analysis of DNA methylation in low cell numbers by reduced representation bisulfite sequencing.

Smallwood SA, Kelsey G.

Methods Mol Biol. 2012;925:187-97. doi: 10.1007/978-1-62703-011-3_12.


Plasma Shh levels reduced in pancreatic cancer patients.

El-Zaatari M, Daignault S, Tessier A, Kelsey G, Travnikar LA, Cantu EF, Lee J, Plonka CM, Simeone DM, Anderson MA, Merchant JL.

Pancreas. 2012 Oct;41(7):1019-28. doi: 10.1097/MPA.0b013e31824a0eeb.


Loss of XLαs (extra-large αs) imprinting results in early postnatal hypoglycemia and lethality in a mouse model of pseudohypoparathyroidism Ib.

Fernández-Rebollo E, Maeda A, Reyes M, Turan S, Fröhlich LF, Plagge A, Kelsey G, Jüppner H, Bastepe M.

Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6638-43. doi: 10.1073/pnas.1117608109. Epub 2012 Apr 10.


Imprinted genes … and the number is?

Kelsey G, Bartolomei MS.

PLoS Genet. 2012;8(3):e1002601. doi: 10.1371/journal.pgen.1002601. Epub 2012 Mar 29. No abstract available.


De novo DNA methylation: a germ cell perspective.

Smallwood SA, Kelsey G.

Trends Genet. 2012 Jan;28(1):33-42. doi: 10.1016/j.tig.2011.09.004. Epub 2011 Oct 21. Review.


A web of imprinting in stem cells.

Kelsey G.

Cell Stem Cell. 2011 Sep 2;9(3):177-8. doi: 10.1016/j.stem.2011.08.008.


Imprinted genes and hypothalamic function.

Ivanova E, Kelsey G.

J Mol Endocrinol. 2011 Sep 19;47(2):R67-74. doi: 10.1530/JME-11-0065. Print 2011 Oct. Review.


DNA methylation: a new twist in the tail.

Kelsey G.

Cell Res. 2011 Aug;21(8):1155-6. doi: 10.1038/cr.2011.110. Epub 2011 Jul 5. No abstract available.


Dynamic CpG island methylation landscape in oocytes and preimplantation embryos.

Smallwood SA, Tomizawa S, Krueger F, Ruf N, Carli N, Segonds-Pichon A, Sato S, Hata K, Andrews SR, Kelsey G.

Nat Genet. 2011 Jun 26;43(8):811-4. doi: 10.1038/ng.864.

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