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Diversity and geochemical community assembly processes of the living rare biosphere in a sand-and-gravel aquifer ecosystem in the Midwestern United States.

Yamamoto K, Hackley KC, Kelly WR, Panno SV, Sekiguchi Y, Sanford RA, Liu WT, Kamagata Y, Tamaki H.

Sci Rep. 2019 Sep 17;9(1):13484. doi: 10.1038/s41598-019-49996-z.


A Systematic Review of the Orthopaedic Literature Involving National Football League Players.

Kluczynski MA, Kelly WH, Lashomb WM, Bisson LJ.

Orthop J Sports Med. 2019 Aug 20;7(8):2325967119864356. doi: 10.1177/2325967119864356. eCollection 2019 Aug. Review.


Mortality and Hospitalization Risk Following Oral Androgen Signaling Inhibitors Among Men with Advanced Prostate Cancer by Pre-existing Cardiovascular Comorbidities.

Lu-Yao G, Nikita N, Keith SW, Nightingale G, Gandhi K, Hegarty SE, Rebbeck TR, Chapman A, Kantoff PW, Cullen J, Gomella L, Kelly WK.

Eur Urol. 2019 Aug 2. pii: S0302-2838(19)30585-8. doi: 10.1016/j.eururo.2019.07.031. [Epub ahead of print]


Diverse hydrogen production and consumption pathways influence methane production in ruminants.

Greening C, Geier R, Wang C, Woods LC, Morales SE, McDonald MJ, Rushton-Green R, Morgan XC, Koike S, Leahy SC, Kelly WJ, Cann I, Attwood GT, Cook GM, Mackie RI.

ISME J. 2019 Oct;13(10):2617-2632. doi: 10.1038/s41396-019-0464-2. Epub 2019 Jun 26.


Androgen decline and survival during docetaxel therapy in metastatic castration resistant prostate cancer (mCRPC).

Ryan CJ, Dutta S, Kelly WK, Russell C, Small EJ, Morris MJ, Taplin ME, Halabi S; From The Alliance for Clinical Trials in Oncology Genitourinary Committee.

Prostate Cancer Prostatic Dis. 2019 May 3. doi: 10.1038/s41391-019-0152-3. [Epub ahead of print]


Improved taxonomic assignment of rumen bacterial 16S rRNA sequences using a revised SILVA taxonomic framework.

Henderson G, Yilmaz P, Kumar S, Forster RJ, Kelly WJ, Leahy SC, Guan LL, Janssen PH.

PeerJ. 2019 Mar 5;7:e6496. doi: 10.7717/peerj.6496. eCollection 2019.


Single injection of PTH improves osteoclastic parameters of remodeling at a stress fracture site in rats.

Bakr MM, Kelly WL, Brunt AR, Paterson BC, Massa HM, Morrison NA, Forwood MR.

J Orthop Res. 2019 May;37(5):1172-1182. doi: 10.1002/jor.24262. Epub 2019 Mar 21.


Comparative Genome Analysis of Lactococcus lactis Indicates Niche Adaptation and Resolves Genotype/Phenotype Disparity.

Wels M, Siezen R, van Hijum S, Kelly WJ, Bachmann H.

Front Microbiol. 2019 Jan 31;10:4. doi: 10.3389/fmicb.2019.00004. eCollection 2019.


Genomic insights from Monoglobus pectinilyticus: a pectin-degrading specialist bacterium in the human colon.

Kim CC, Healey GR, Kelly WJ, Patchett ML, Jordens Z, Tannock GW, Sims IM, Bell TJ, Hedderley D, Henrissat B, Rosendale DI.

ISME J. 2019 Jun;13(6):1437-1456. doi: 10.1038/s41396-019-0363-6. Epub 2019 Feb 6.


In Reply to Maholtz.

Andrews MA, Kelly WF, DeZee KJ.

Acad Med. 2019 Feb;94(2):153-154. doi: 10.1097/ACM.0000000000002527. No abstract available.


Microplastic Contamination in Karst Groundwater Systems.

Panno SV, Kelly WR, Scott J, Zheng W, McNeish RE, Holm N, Hoellein TJ, Baranski EL.

Ground Water. 2019 Mar;57(2):189-196. doi: 10.1111/gwat.12862. Epub 2019 Feb 12.


Counterpoint-Prostate Cancer Genomic Analysis: Routine or Research Only?

Kelly WK, Knudsen KE.

Oncology (Williston Park). 2018 Dec 17;32(12):607, 630-2. No abstract available.


Rapid analysis of metagenomic data using signature-based clustering.

Chappell T, Geva S, Hogan JM, Huygens F, Rathnayake IU, Rudd S, Kelly W, Perrin D.

BMC Bioinformatics. 2018 Dec 21;19(Suppl 20):509. doi: 10.1186/s12859-018-2540-4.


Overall Survival of Black and White Men With Metastatic Castration-Resistant Prostate Cancer Treated With Docetaxel.

Halabi S, Dutta S, Tangen CM, Rosenthal M, Petrylak DP, Thompson IM Jr, Chi KN, Araujo JC, Logothetis C, Quinn DI, Fizazi K, Morris MJ, Eisenberger MA, George DJ, De Bono JS, Higano CS, Tannock IF, Small EJ, Kelly WK.

J Clin Oncol. 2019 Feb 10;37(5):403-410. doi: 10.1200/JCO.18.01279. Epub 2018 Dec 21.


Butyrivibrio hungatei MB2003 Competes Effectively for Soluble Sugars Released by Butyrivibrio proteoclasticus B316T during Growth on Xylan or Pectin.

Palevich N, Kelly WJ, Ganesh S, Rakonjac J, Attwood GT.

Appl Environ Microbiol. 2019 Jan 23;85(3). pii: e02056-18. doi: 10.1128/AEM.02056-18. Print 2019 Feb 1.


PARP-1 regulates DNA repair factor availability.

Schiewer MJ, Mandigo AC, Gordon N, Huang F, Gaur S, de Leeuw R, Zhao SG, Evans J, Han S, Parsons T, Birbe R, McCue P, McNair C, Chand SN, Cendon-Florez Y, Gallagher P, McCann JJ, Poudel Neupane N, Shafi AA, Dylgjeri E, Brand LJ, Visakorpi T, Raj GV, Lallas CD, Trabulsi EJ, Gomella LG, Dicker AP, Kelly WK, Leiby BE, Knudsen B, Feng FY, Knudsen KE.

EMBO Mol Med. 2018 Dec;10(12). pii: e8816. doi: 10.15252/emmm.201708816.


Germline genetic testing for inherited prostate cancer in practice: Implications for genetic testing, precision therapy, and cascade testing.

Giri VN, Hegarty SE, Hyatt C, O'Leary E, Garcia J, Knudsen KE, Kelly WK, Gomella LG.

Prostate. 2019 Mar;79(4):333-339. doi: 10.1002/pros.23739. Epub 2018 Nov 18.


Neoadjuvant Dose-dense Gemcitabine and Cisplatin in Muscle-invasive Bladder Cancer: Results of a Phase 2 Trial.

Anari F, O'Neill J, Choi W, Chen DYT, Haseebuddin M, Kutikov A, Dulaimi E, Alpaugh RK, Devarajan K, Greenberg RE, Bilusic M, Wong YN, Viterbo R, Hoffman-Censits JH, Lallas CD, Trabulsi EJ, Smaldone M, Geynisman DM, Zibelman M, Lin J, Kelly WK, Uzzo R, McConkey D, Plimack ER.

Eur Urol Oncol. 2018 May;1(1):54-60. doi: 10.1016/j.euo.2018.02.007. Epub 2018 Jun 6.


Convulsive seizures and EEG spikes after lateral fluid-percussion injury in the rat.

Smith D, Rau T, Poulsen A, MacWilliams Z, Patterson D, Kelly W, Poulsen D.

Epilepsy Res. 2018 Nov;147:87-94. doi: 10.1016/j.eplepsyres.2018.09.005. Epub 2018 Sep 17.


Why Does This Learner Perform Poorly on Tests? Using Self-Regulated Learning Theory to Diagnose the Problem and Implement Solutions.

Andrews MA, Kelly WF, DeZee KJ.

Acad Med. 2018 Apr;93(4):612-615. doi: 10.1097/ACM.0000000000001422.


Circulating microRNAs as biomarkers in traumatic brain injury.

Toffolo K, Osei J, Kelly W, Poulsen A, Donahue K, Wang J, Hunter M, Bard J, Wang J, Poulsen D.

Neuropharmacology. 2019 Feb;145(Pt B):199-208. doi: 10.1016/j.neuropharm.2018.08.028. Epub 2018 Sep 7. Review.


Multicenter Phase 2 Trial of Gemcitabine, Carboplatin, and Sorafenib in Patients With Metastatic or Unresectable Transitional-Cell Carcinoma.

Hurwitz ME, Markowski P, Yao X, Deshpande H, Patel J, Mortazavi A, Donadio A, Stein MN, Kelly WK, Petrylak DP, Mehnert JM.

Clin Genitourin Cancer. 2018 Dec;16(6):437-444.e6. doi: 10.1016/j.clgc.2018.07.021. Epub 2018 Jul 29.


Biosynthesis of the Thiopeptins and Identification of an F420H2-Dependent Dehydropiperidine Reductase.

Ichikawa H, Bashiri G, Kelly WL.

J Am Chem Soc. 2018 Aug 29;140(34):10749-10756. doi: 10.1021/jacs.8b04238. Epub 2018 Aug 17.


Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM121-Driven E2F1, MYC, and AR Nuclear Import.

Rodriguez-Bravo V, Pippa R, Song WM, Carceles-Cordon M, Dominguez-Andres A, Fujiwara N, Woo J, Koh AP, Ertel A, Lokareddy RK, Cuesta-Dominguez A, Kim RS, Rodriguez-Fernandez I, Li P, Gordon R, Hirschfield H, Prats JM, Reddy EP, Fatatis A, Petrylak DP, Gomella L, Kelly WK, Lowe SW, Knudsen KE, Galsky MD, Cingolani G, Lujambio A, Hoshida Y, Domingo-Domenech J.

Cell. 2018 Aug 23;174(5):1200-1215.e20. doi: 10.1016/j.cell.2018.07.015. Epub 2018 Aug 9.


Prostate cancer sheds the αvβ3 integrin in vivo through exosomes.

Krishn SR, Singh A, Bowler N, Duffy AN, Friedman A, Fedele C, Kurtoglu S, Tripathi SK, Wang K, Hawkins A, Sayeed A, Goswami CP, Thakur ML, Iozzo RV, Peiper SC, Kelly WK, Languino LR.

Matrix Biol. 2019 Apr;77:41-57. doi: 10.1016/j.matbio.2018.08.004. Epub 2018 Aug 8.


Management of Brain Metastases in Epidermal Growth Factor Receptor Mutant Non-Small-Cell Lung Cancer.

Kelly WJ, Shah NJ, Subramaniam DS.

Front Oncol. 2018 Jul 3;8:208. doi: 10.3389/fonc.2018.00208. eCollection 2018. Review.


Chronic Obstructive Pulmonary Disease Education in Pulmonary Rehabilitation. An Official American Thoracic Society/Thoracic Society of Australia and New Zealand/Canadian Thoracic Society/British Thoracic Society Workshop Report.

Blackstock FC, Lareau SC, Nici L, ZuWallack R, Bourbeau J, Buckley M, Durning SJ, Effing TW, Egbert E, Goldstein RS, Kelly W, Lee A, Meek PM, Singh S; American Thoracic Society, Thoracic Society of Australia and New Zealand, Canadian Thoracic Society, and British Thoracic Society.

Ann Am Thorac Soc. 2018 Jul;15(7):769-784. doi: 10.1513/AnnalsATS.201804-253WS.


Thymosin beta 4 induces significant changes in the plasma miRNA profile following severe traumatic brain injury in the rat lateral fluid percussion injury model.

Osei J, Kelly W, Toffolo K, Donahue K, Levy B, Bard J, Wang J, Levy E, Nowak N, Poulsen D.

Expert Opin Biol Ther. 2018 Jul;18(sup1):159-164. doi: 10.1080/14712598.2018.1484102.


Identification of a Genomic Region between SLC29A1 and HSP90AB1 Associated with Risk of Bevacizumab-Induced Hypertension: CALGB 80405 (Alliance).

Li M, Mulkey F, Jiang C, O'Neil BH, Schneider BP, Shen F, Friedman PN, Momozawa Y, Kubo M, Niedzwiecki D, Hochster HS, Lenz HJ, Atkins JN, Rugo HS, Halabi S, Kelly WK, McLeod HL, Innocenti F, Ratain MJ, Venook AP, Owzar K, Kroetz DL.

Clin Cancer Res. 2018 Oct 1;24(19):4734-4744. doi: 10.1158/1078-0432.CCR-17-1523. Epub 2018 Jun 5.


Bifidobacterium pseudolongum in the Ceca of Rats Fed Hi-Maize Starch Has Characteristics of a Keystone Species in Bifidobacterial Blooms.

Centanni M, Lawley B, Butts CA, Roy NC, Lee J, Kelly WJ, Tannock GW.

Appl Environ Microbiol. 2018 Jul 17;84(15). pii: e00547-18. doi: 10.1128/AEM.00547-18. Print 2018 Aug 1.


MAPK Reliance via Acquired CDK4/6 Inhibitor Resistance in Cancer.

de Leeuw R, McNair C, Schiewer MJ, Neupane NP, Brand LJ, Augello MA, Li Z, Cheng LC, Yoshida A, Courtney SM, Hazard ES, Hardiman G, Hussain MH, Diehl JA, Drake JM, Kelly WK, Knudsen KE.

Clin Cancer Res. 2018 Sep 1;24(17):4201-4214. doi: 10.1158/1078-0432.CCR-18-0410. Epub 2018 May 8.


Cultivation and sequencing of rumen microbiome members from the Hungate1000 Collection.

Seshadri R, Leahy SC, Attwood GT, Teh KH, Lambie SC, Cookson AL, Eloe-Fadrosh EA, Pavlopoulos GA, Hadjithomas M, Varghese NJ, Paez-Espino D; Hungate1000 project collaborators, Perry R, Henderson G, Creevey CJ, Terrapon N, Lapebie P, Drula E, Lombard V, Rubin E, Kyrpides NC, Henrissat B, Woyke T, Ivanova NN, Kelly WJ.

Nat Biotechnol. 2018 Apr;36(4):359-367. doi: 10.1038/nbt.4110. Epub 2018 Mar 19.


Multidisciplinary Clinical Treatment of Head and Neck Cancer.

Mark JR, Kelly WK, Gomella LG.

JAMA Otolaryngol Head Neck Surg. 2018 May 1;144(5):460-461. doi: 10.1001/jamaoto.2017.3437. No abstract available.


The RIME Model Provides a Context for Entrustable Professional Activities Across Undergraduate Medical Education.

Meyer EG, Kelly WF, Hemmer PA, Pangaro LN.

Acad Med. 2018 Jun;93(6):954. doi: 10.1097/ACM.0000000000002211. No abstract available.


Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer.

Lu H, Bowler N, Harshyne LA, Craig Hooper D, Krishn SR, Kurtoglu S, Fedele C, Liu Q, Tang HY, Kossenkov AV, Kelly WK, Wang K, Kean RB, Weinreb PH, Yu L, Dutta A, Fortina P, Ertel A, Stanczak M, Forsberg F, Gabrilovich DI, Speicher DW, Altieri DC, Languino LR.

Matrix Biol. 2018 Sep;70:20-35. doi: 10.1016/j.matbio.2018.03.009. Epub 2018 Mar 9.


Clinical activity of nivolumab in patients with non-clear cell renal cell carcinoma.

Koshkin VS, Barata PC, Zhang T, George DJ, Atkins MB, Kelly WJ, Vogelzang NJ, Pal SK, Hsu J, Appleman LJ, Ornstein MC, Gilligan T, Grivas P, Garcia JA, Rini BI.

J Immunother Cancer. 2018 Jan 29;6(1):9. doi: 10.1186/s40425-018-0319-9.


Detection of sleep-disordered breathing with ambulatory Holter monitoring.

Grasso I, Haigney M, Mortara D, Collen JF, Hostler J, Moores A, Sheikh K, Kelly W.

Sleep Breath. 2018 Dec;22(4):1021-1028. doi: 10.1007/s11325-018-1623-9. Epub 2018 Jan 20.


Evaluation of a 27-gene inherited cancer panel across 630 consecutive patients referred for testing in a clinical diagnostic laboratory.

Gardner SA, Weymouth KS, Kelly WS, Bogdanova E, Chen W, Lupu D, Suhl J, Zeng Q, Geigenmüller U, Boles D, Okamoto PM, McDowell G, Hayden MA, Nagan N.

Hered Cancer Clin Pract. 2018 Jan 4;16:1. doi: 10.1186/s13053-017-0083-8. eCollection 2018.


Toward Understanding Phage:Host Interactions in the Rumen; Complete Genome Sequences of Lytic Phages Infecting Rumen Bacteria.

Gilbert RA, Kelly WJ, Altermann E, Leahy SC, Minchin C, Ouwerkerk D, Klieve AV.

Front Microbiol. 2017 Dec 5;8:2340. doi: 10.3389/fmicb.2017.02340. eCollection 2017.


Role of Genetic Testing for Inherited Prostate Cancer Risk: Philadelphia Prostate Cancer Consensus Conference 2017.

Giri VN, Knudsen KE, Kelly WK, Abida W, Andriole GL, Bangma CH, Bekelman JE, Benson MC, Blanco A, Burnett A, Catalona WJ, Cooney KA, Cooperberg M, Crawford DE, Den RB, Dicker AP, Eggener S, Fleshner N, Freedman ML, Hamdy FC, Hoffman-Censits J, Hurwitz MD, Hyatt C, Isaacs WB, Kane CJ, Kantoff P, Karnes RJ, Karsh LI, Klein EA, Lin DW, Loughlin KR, Lu-Yao G, Malkowicz SB, Mann MJ, Mark JR, McCue PA, Miner MM, Morgan T, Moul JW, Myers RE, Nielsen SM, Obeid E, Pavlovich CP, Peiper SC, Penson DF, Petrylak D, Pettaway CA, Pilarski R, Pinto PA, Poage W, Raj GV, Rebbeck TR, Robson ME, Rosenberg MT, Sandler H, Sartor O, Schaeffer E, Schwartz GF, Shahin MS, Shore ND, Shuch B, Soule HR, Tomlins SA, Trabulsi EJ, Uzzo R, Vander Griend DJ, Walsh PC, Weil CJ, Wender R, Gomella LG.

J Clin Oncol. 2018 Feb 1;36(4):414-424. doi: 10.1200/JCO.2017.74.1173. Epub 2017 Dec 13. Review.


The complete genome sequence of the rumen bacterium Butyrivibrio hungatei MB2003.

Palevich N, Kelly WJ, Leahy SC, Altermann E, Rakonjac J, Attwood GT.

Stand Genomic Sci. 2017 Dec 4;12:72. doi: 10.1186/s40793-017-0285-8. eCollection 2017.


Product review on the Anti-PD-L1 antibody atezolizumab.

Shah NJ, Kelly WJ, Liu SV, Choquette K, Spira A.

Hum Vaccin Immunother. 2018 Feb 1;14(2):269-276. doi: 10.1080/21645515.2017.1403694. Epub 2017 Dec 20.


Sporulation capability and amylosome conservation among diverse human colonic and rumen isolates of the keystone starch-degrader Ruminococcus bromii.

Mukhopadhya I, Moraïs S, Laverde-Gomez J, Sheridan PO, Walker AW, Kelly W, Klieve AV, Ouwerkerk D, Duncan SH, Louis P, Koropatkin N, Cockburn D, Kibler R, Cooper PJ, Sandoval C, Crost E, Juge N, Bayer EA, Flint HJ.

Environ Microbiol. 2018 Jan;20(1):324-336. doi: 10.1111/1462-2920.14000. Epub 2017 Dec 7.


Optimizing performance of semi-continuous cell culture in an ambr15™ microbioreactor using dynamic flux balance modeling.

Kelly W, Veigne S, Li X, Subramanian SS, Huang Z, Schaefer E.

Biotechnol Prog. 2018 Mar;34(2):420-431. doi: 10.1002/btpr.2585. Epub 2017 Nov 30.


CHEST: Home of the Clinician-Educator.

Kelly WF, Niven AS; CHEST Education Committee*.

Chest. 2018 Mar;153(3):598-600. doi: 10.1016/j.chest.2017.10.029. Epub 2017 Nov 28.


Naming disease states for clinical utility in prostate cancer: a rose by any other name might not smell as sweet.

Armstrong AJ, Antonarakis ES, Taplin ME, Kelly WK, Beltran H, Fizazi K, Dahut WL, Shore N, Slovin S, George D, Carducci MA, Corn P, Danila D, Dreicer R, Heath E, Rathkopf D, Liu G, Nanus D, Stein M, Smith MR, Sternberg C, Wilding G, Nelson PS, Halabi S, Kantoff P, Clarke NW, Evans CP, Heidenreich A, Mottet N, Gleave M, Morris MJ, Scher HI.

Ann Oncol. 2018 Jan 1;29(1):23-25. doi: 10.1093/annonc/mdx648. No abstract available.


Monoglobus pectinilyticus gen. nov., sp. nov., a pectinolytic bacterium isolated from human faeces.

Kim CC, Kelly WJ, Patchett ML, Tannock GW, Jordens Z, Stoklosinski HM, Taylor JW, Sims IM, Bell TJ, Rosendale DI.

Int J Syst Evol Microbiol. 2017 Dec;67(12):4992-4998. doi: 10.1099/ijsem.0.002395. Epub 2017 Oct 17.


The changing cost to prevent diabetes: A retrospective analysis of the Diabetes Prevention Program.

Carris NW, Cheng F, Kelly WN.

J Am Pharm Assoc (2003). 2017 Nov - Dec;57(6):717-722. doi: 10.1016/j.japh.2017.05.015. Epub 2017 Aug 12.


Gene and transcript abundances of bacterial type III secretion systems from the rumen microbiome are correlated with methane yield in sheep.

Kamke J, Soni P, Li Y, Ganesh S, Kelly WJ, Leahy SC, Shi W, Froula J, Rubin EM, Attwood GT.

BMC Res Notes. 2017 Aug 8;10(1):367. doi: 10.1186/s13104-017-2671-0.


Recharge and Groundwater Flow Within an Intracratonic Basin, Midwestern United States.

Panno SV, Askari Z, Kelly WR, Parris TM, Hackley KC.

Ground Water. 2018 Jan;56(1):32-45. doi: 10.1111/gwat.12545. Epub 2017 Jul 17.


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