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Impact of Checkpoint Inhibitor Pneumonitis on Survival in NSCLC Patients Receiving Immune Checkpoint Immunotherapy.

Suresh K, Psoter KJ, Voong KR, Shankar B, Forde PM, Ettinger DS, Marrone KA, Kelly RJ, Hann CL, Levy B, Feliciano JL, Brahmer JR, Feller-Kopman D, Lerner AD, Lee H, Yarmus L, Hales RK, D'Alessio F, Danoff SK, Naidoo J.

J Thorac Oncol. 2018 Nov 30. pii: S1556-0864(18)33493-2. doi: 10.1016/j.jtho.2018.11.016. [Epub ahead of print]


α-galactosidase A deficiency promotes von Willebrand factor secretion in models of Fabry disease.

Kang JJ, Kaissarian NM, Desch KC, Kelly RJ, Shu L, Bodary PF, Shayman JA.

Kidney Int. 2019 Jan;95(1):149-159. doi: 10.1016/j.kint.2018.08.033. Epub 2018 Nov 22.


Pneumonitis in Non-Small Cell Lung Cancer Patients Receiving Immune Checkpoint Immunotherapy: Incidence and Risk Factors.

Suresh K, Voong KR, Shankar B, Forde PM, Ettinger DS, Marrone KA, Kelly RJ, Hann CL, Levy B, Feliciano JL, Brahmer JR, Feller-Kopman D, Lerner AD, Lee H, Yarmus L, D'Alessio F, Hales RK, Lin CT, Psoter KJ, Danoff SK, Naidoo J.

J Thorac Oncol. 2018 Dec;13(12):1930-1939. doi: 10.1016/j.jtho.2018.08.2035. Epub 2018 Sep 26.


Dabrafenib and trametinib for the treatment of non-small cell lung cancer.

Kelly RJ.

Expert Rev Anticancer Ther. 2018 Nov;18(11):1063-1068. doi: 10.1080/14737140.2018.1521272. Epub 2018 Sep 13.


Serial Endoscopic Evaluation of Esophageal Disease in a Cancer Model: A Paradigm Shift for Esophageal Adenocarcinoma (EAC) Drug Discovery and Development.

Omstead AN, Kosovec JE, Matsui D, Martin SA, Smith MA, Aaron Guel D, Kolano J, Komatsu Y, Habib F, Lai C, Christopher K, Kelly RJ, Zaidi AH, Jobe BA.

Cancer Invest. 2018;36(7):363-370. doi: 10.1080/07357907.2018.1499029. Epub 2018 Aug 24.


Variability and profiles of lipophilic toxins in bivalves from Great Britain during five and a half years of monitoring: Okadaic acid, dinophysis toxins and pectenotoxins.

Dhanji-Rapkova M, O'Neill A, Maskrey BH, Coates L, Teixeira Alves M, Kelly RJ, Hatfield RG, Rowland-Pilgrim SJ, Lewis AM, Algoet M, Turner AD.

Harmful Algae. 2018 Jul;77:66-80. doi: 10.1016/j.hal.2018.05.011. Epub 2018 Jun 19.


Family Functioning and Children's Sleep.

El-Sheikh M, Kelly RJ.

Child Dev Perspect. 2017 Dec;11(4):264-269. doi: 10.1111/cdep.12243. Epub 2017 Jul 21.


Single agent anti PD-1 inhibitors in esophageal cancer-a first step in a new therapeutic direction.

Walsh EM, Kelly RJ.

J Thorac Dis. 2018 Mar;10(3):1308-1313. doi: 10.21037/jtd.2018.03.43. No abstract available.


Reciprocal Relations Between Parental Problem Drinking and Children's Sleep: The Role of Socioeconomic Adversity.

Kelly RJ, El-Sheikh M.

Child Dev. 2018 Apr 18. doi: 10.1111/cdev.13074. [Epub ahead of print]


Maternal immunization increases nestling energy expenditure, immune function, and fledging success in a passerine bird.

Burness G, Moher D, Ben-Ezra N, Kelly RJ, Hasselquist D, Chin EH.

Biol Open. 2018 Apr 4;7(4). pii: bio028803. doi: 10.1242/bio.028803.


Randomized phase 2 study of tivantinib plus erlotinib versus single-agent chemotherapy in previously treated KRAS mutant advanced non-small cell lung cancer.

Gerber DE, Socinski MA, Neal JW, Wakelee HA, Shirai K, Sequist LV, Rosovsky RP, Lilenbaum RC, Bastos BR, Huang C, Johnson ML, Hesketh PJ, Subramaniam DS, Dietrich MF, Chai F, Wang Y, Kazakin J, Schwartz B, Schiller JH, Brahmer JR, Kelly RJ.

Lung Cancer. 2018 Mar;117:44-49. doi: 10.1016/j.lungcan.2018.01.010. Epub 2018 Feb 3.


A Randomized Phase II Study of Metformin plus Paclitaxel/Carboplatin/Bevacizumab in Patients with Chemotherapy-Naïve Advanced or Metastatic Nonsquamous Non-Small Cell Lung Cancer.

Marrone KA, Zhou X, Forde PM, Purtell M, Brahmer JR, Hann CL, Kelly RJ, Coleman B, Gabrielson E, Rosner GL, Ettinger DS.

Oncologist. 2018 Jul;23(7):859-865. doi: 10.1634/theoncologist.2017-0465. Epub 2018 Feb 27.


Metastatic joint involvement or inflammatory arthritis? A conundrum with immune checkpoint inhibitor-related adverse events.

Albayda J, Bingham CO 3rd, Shah AA, Kelly RJ, Cappelli L.

Rheumatology (Oxford). 2018 Apr 1;57(4):760-762. doi: 10.1093/rheumatology/kex470. No abstract available.


Corneal ulcers in general practice.

Arbabi EM, Kelly RJ, Carrim ZI.

Br J Gen Pract. 2018 Jan;68(666):49-50. doi: 10.3399/bjgp17X694385. No abstract available.


CDK4/6 dual inhibitor abemaciclib demonstrates compelling preclinical activity against esophageal adenocarcinoma: a novel therapeutic option for a deadly disease.

Kosovec JE, Zaidi AH, Omstead AN, Matsui D, Biedka MJ, Cox EJ, Campbell PT, Biederman RWW, Kelly RJ, Jobe BA.

Oncotarget. 2017 Nov 1;8(59):100421-100432. doi: 10.18632/oncotarget.22244. eCollection 2017 Nov 21.


Challenges, Perceptions, and Readiness of Oncology Clinicians for the MACRA Quality Payment Program.

Nabhan C, Jeune-Smith Y, Klinefelter P, Kelly RJ, Feinberg BA.

JAMA Oncol. 2018 Feb 1;4(2):252-253. doi: 10.1001/jamaoncol.2017.3773. No abstract available.


The management of localized esophageal squamous cell carcinoma: Western approach.

Zaidi N, Kelly RJ.

Chin Clin Oncol. 2017 Oct;6(5):46. doi: 10.21037/cco.2017.07.07. Review.


A Comparison of Walking Gait Following Mechanical and Kinematic Alignment in Total Knee Joint Replacement.

McNair PJ, Boocock MG, Dominick ND, Kelly RJ, Farrington BJ, Young SW.

J Arthroplasty. 2018 Feb;33(2):560-564. doi: 10.1016/j.arth.2017.09.031. Epub 2017 Sep 21.


High yield reproducible rat model recapitulating human Barrett's carcinogenesis.

Matsui D, Omstead AN, Kosovec JE, Komatsu Y, Lloyd EJ, Raphael H, Kelly RJ, Zaidi AH, Jobe BA.

World J Gastroenterol. 2017 Sep 7;23(33):6077-6087. doi: 10.3748/wjg.v23.i33.6077.


A Phase I, Dose Escalation Study of Oral ASP8273 in Patients with Non-small Cell Lung Cancers with Epidermal Growth Factor Receptor Mutations.

Yu HA, Spira A, Horn L, Weiss J, West H, Giaccone G, Evans T, Kelly RJ, Desai B, Krivoshik A, Moran D, Poondru S, Jie F, Aoyama K, Keating A, Oxnard GR.

Clin Cancer Res. 2017 Dec 15;23(24):7467-7473. doi: 10.1158/1078-0432.CCR-17-1447. Epub 2017 Sep 27.


The Dynamic and Transient Immune Microenvironment in Locally Advanced Esophageal Adenocarcinoma Post Chemoradiation.

Kelly RJ, Zaidi AH, Smith MA, Omstead AN, Kosovec JE, Matsui D, Martin SA, DiCarlo C, Werts ED, Silverman JF, Wang DH, Jobe BA.

Ann Surg. 2018 Dec;268(6):992-999. doi: 10.1097/SLA.0000000000002410.


Outcome of Azacitidine Therapy in Acute Myeloid Leukemia Is not Improved by Concurrent Vorinostat Therapy but Is Predicted by a Diagnostic Molecular Signature.

Craddock CF, Houlton AE, Quek LS, Ferguson P, Gbandi E, Roberts C, Metzner M, Garcia-Martin N, Kennedy A, Hamblin A, Raghavan M, Nagra S, Dudley L, Wheatley K, McMullin MF, Pillai SP, Kelly RJ, Siddique S, Dennis M, Cavenagh JD, Vyas P.

Clin Cancer Res. 2017 Nov 1;23(21):6430-6440. doi: 10.1158/1078-0432.CCR-17-1423. Epub 2017 Aug 1.


Scientific Advances in Thoracic Oncology 2016.

Soo RA, Stone ECA, Cummings KM, Jett JR, Field JK, Groen HJM, Mulshine JL, Yatabe Y, Bubendorf L, Dacic S, Rami-Porta R, Detterbeck FC, Lim E, Asamura H, Donington J, Wakelee HA, Wu YL, Higgins K, Senan S, Solomon B, Kim DW, Johnson M, Yang JCH, Sequist LV, Shaw AT, Ahn MJ, Costa DB, Patel JD, Horn L, Gettinger S, Peters S, Wynes MW, Faivre-Finn C, Rudin CM, Tsao A, Baas P, Kelly RJ, Leighl NB, Scagliotti GV, Gandara DR, Hirsch FR, Spigel DR.

J Thorac Oncol. 2017 Aug;12(8):1183-1209. doi: 10.1016/j.jtho.2017.05.019. Epub 2017 Jun 1. Review.


Immunotherapy for Esophageal and Gastric Cancer.

Kelly RJ.

Am Soc Clin Oncol Educ Book. 2017;37:292-300. doi: 10.14694/EDBK_175231. Review.


The Evolving Role of Checkpoint Inhibitors in the Management of Gastroesophageal Cancer.

Murphy AG, Kelly RJ.

Hematol Oncol Clin North Am. 2017 Jun;31(3):485-498. doi: 10.1016/j.hoc.2017.01.007. Epub 2017 Mar 30. Review.


Primary tumor microRNA signature predicts recurrence and survival in patients with locally advanced esophageal adenocarcinoma.

Matsui D, Zaidi AH, Martin SA, Omstead AN, Kosovec JE, Huleihel L, Saldin LT, DiCarlo C, Silverman JF, Hoppo T, Finley GG, Badylak SF, Kelly RJ, Jobe BA.

Oncotarget. 2016 Dec 6;7(49):81281-81291. doi: 10.18632/oncotarget.12832. Review.


Checkpoint Inhibitors in Lung Cancer Are Not Immune from Cost-Effectiveness Analysis.

Kelly RJ, Smith TJ.

J Thorac Oncol. 2016 Nov;11(11):1814-1816. doi: 10.1016/j.jtho.2016.07.028. No abstract available.


PI3K/mTOR Dual Inhibitor, LY3023414, Demonstrates Potent Antitumor Efficacy Against Esophageal Adenocarcinoma in a Rat Model.

Zaidi AH, Kosovec JE, Matsui D, Omstead AN, Raj M, Rao RR, Biederman RWW, Finley GG, Landreneau RJ, Kelly RJ, Jobe BA.

Ann Surg. 2017 Jul;266(1):91-98. doi: 10.1097/SLA.0000000000001908.


Osteoconduction in keratin-hydroxyapatite composite bone-graft substitutes.

Dias GJ, Mahoney P, Hung NA, Sharma LA, Kalita P, Smith RA, Kelly RJ, Ali A.

J Biomed Mater Res B Appl Biomater. 2017 Oct;105(7):2034-2044. doi: 10.1002/jbm.b.33735. Epub 2016 Jul 8.


Helm's Alee: Setting a New Course.

Kelly RJ.

J Leg Med. 2015 Apr-Jun;36(2):101-2. doi: 10.1080/01947648.2015.1168653. No abstract available.


Parental problem drinking and children's sleep: The role of ethnicity and socioeconomic status.

Kelly RJ, El-Sheikh M.

J Fam Psychol. 2016 Sep;30(6):708-19. doi: 10.1037/fam0000209. Epub 2016 Apr 21.


Dabrafenib in patients with BRAF(V600E)-positive advanced non-small-cell lung cancer: a single-arm, multicentre, open-label, phase 2 trial.

Planchard D, Kim TM, Mazieres J, Quoix E, Riely G, Barlesi F, Souquet PJ, Smit EF, Groen HJ, Kelly RJ, Cho BC, Socinski MA, Pandite L, Nase C, Ma B, D'Amelio A Jr, Mookerjee B, Curtis CM Jr, Johnson BE.

Lancet Oncol. 2016 May;17(5):642-50. doi: 10.1016/S1470-2045(16)00077-2. Epub 2016 Apr 11.


Scientific Advances in Lung Cancer 2015.

Tsao AS, Scagliotti GV, Bunn PA Jr, Carbone DP, Warren GW, Bai C, de Koning HJ, Yousaf-Khan AU, McWilliams A, Tsao MS, Adusumilli PS, Rami-Porta R, Asamura H, Van Schil PE, Darling GE, Ramalingam SS, Gomez DR, Rosenzweig KE, Zimmermann S, Peters S, Ignatius Ou SH, Reungwetwattana T, Jänne PA, Mok TS, Wakelee HA, Pirker R, Mazières J, Brahmer JR, Zhou Y, Herbst RS, Papadimitrakopoulou VA, Redman MW, Wynes MW, Gandara DR, Kelly RJ, Hirsch FR, Pass HI.

J Thorac Oncol. 2016 May;11(5):613-638. doi: 10.1016/j.jtho.2016.03.012. Epub 2016 Mar 22. Review.


Mesothelin Expression in Advanced Gastroesophageal Cancer Represents a Novel Target for Immunotherapy.

Illei PB, Alewine C, Zahurak M, Cowan ML, Montgomery E, Hassan R, Xiang L, Pastan I, Kelly RJ.

Appl Immunohistochem Mol Morphol. 2016 Apr;24(4):246-52. doi: 10.1097/PAI.0000000000000292.


Patterns of PD-L1 expression and CD8 T cell infiltration in gastric adenocarcinomas and associated immune stroma.

Thompson ED, Zahurak M, Murphy A, Cornish T, Cuka N, Abdelfatah E, Yang S, Duncan M, Ahuja N, Taube JM, Anders RA, Kelly RJ.

Gut. 2017 May;66(5):794-801. doi: 10.1136/gutjnl-2015-310839. Epub 2016 Jan 22.


State of the art management of metastatic gastroesophageal cancer.

Murphy AG, Lynch D, Kelly RJ.

Ann Transl Med. 2015 Sep;3(16):236. doi: 10.3978/j.issn.2305-5839.2015.09.19. Review.


Eculizumab in Pregnant Patients with Paroxysmal Nocturnal Hemoglobinuria.

Kelly RJ, Höchsmann B, Szer J, Kulasekararaj A, de Guibert S, Röth A, Weitz IC, Armstrong E, Risitano AM, Patriquin CJ, Terriou L, Muus P, Hill A, Turner MP, Schrezenmeier H, Peffault de Latour R.

N Engl J Med. 2015 Sep 10;373(11):1032-9. doi: 10.1056/NEJMoa1502950.


Patients and Physicians Can Discuss Costs of Cancer Treatment in the Clinic.

Kelly RJ, Forde PM, Elnahal SM, Forastiere AA, Rosner GL, Smith TJ.

J Oncol Pract. 2015 Jul;11(4):308-12. doi: 10.1200/JOP.2015.003780. Epub 2015 May 26.


Trends in the Cost and Use of Targeted Cancer Therapies for the Privately Insured Nonelderly: 2001 to 2011.

Shih YC, Smieliauskas F, Geynisman DM, Kelly RJ, Smith TJ.

J Clin Oncol. 2015 Jul 1;33(19):2190-6. doi: 10.1200/JCO.2014.58.2320. Epub 2015 May 18.


Longitudinal relations between constructive and destructive conflict and couples' sleep.

El-Sheikh M, Kelly RJ, Koss KJ, Rauer AJ.

J Fam Psychol. 2015 Jun;29(3):349-59. doi: 10.1037/fam0000083. Epub 2015 Apr 27.


Immunotherapy in upper GI malignancies.

Murphy A, Kelly RJ.

Curr Treat Options Oncol. 2015 May;16(5):20. doi: 10.1007/s11864-015-0336-6. Review.


From molecular classification to targeted therapeutics: the changing face of systemic therapy in metastatic gastroesophageal cancer.

Murphy A, Kelly RJ.

Gastroenterol Res Pract. 2015;2015:896560. doi: 10.1155/2015/896560. Epub 2015 Feb 17. Review.


Longitudinal relations between children's sleep and body mass index: the moderating role of socioeconomic risk.

Bagley EJ, Kelly RJ, El-Sheikh M.

Sleep Health. 2015 Mar;1(1):44-49. doi: 10.1016/j.sleh.2014.12.001. Epub 2014 Dec 9. No abstract available.


What keeps low-SES children from sleeping well: the role of presleep worries and sleep environment.

Bagley EJ, Kelly RJ, Buckhalt JA, El-Sheikh M.

Sleep Med. 2015 Apr;16(4):496-502. doi: 10.1016/j.sleep.2014.10.008. Epub 2014 Dec 16.


Natural killer (NK) cell function in paroxysmal nocturnal hemoglobinuria: a deficiency of NK cells, but not an NK cell deficiency.

El-Sherbiny YM, Doody GM, Kelly RJ, Hill A, Hillmen P, Cook GP.

Blood. 2015 Feb 19;125(8):1351-2. doi: 10.1182/blood-2014-07-591255. No abstract available.


Bone marrow-derived macrophages from AβPP/PS1 mice are sensitized to the effects of inflammatory stimuli.

Barrett JP, Minogue AM, Jones RS, Ribeiro C, Kelly RJ, Lynch MA.

J Alzheimers Dis. 2015;44(3):949-62. doi: 10.3233/JAD-142076.


Reply to C.G. Azzoli et al and C. Chouaid et al.

Kelly RJ, Hillner BE, Smith T.

J Clin Oncol. 2014 Nov 1;32(31):3579-80. doi: 10.1200/JCO.2014.57.2560. Epub 2014 Sep 8. No abstract available.


Income, ethnicity, and sleep: coping as a moderator.

El-Sheikh M, Kelly RJ, Sadeh A, Buckhalt JA.

Cultur Divers Ethnic Minor Psychol. 2014 Jul;20(3):441-8. doi: 10.1037/a0036699.


Systemic treatment of advanced thymic malignancies.

Kelly RJ.

Am Soc Clin Oncol Educ Book. 2014:e367-73. doi: 10.14694/EdBook_AM.2014.34.e367. Review.


New strategies in lung cancer: epigenetic therapy for non-small cell lung cancer.

Forde PM, Brahmer JR, Kelly RJ.

Clin Cancer Res. 2014 May 1;20(9):2244-8. doi: 10.1158/1078-0432.CCR-13-2088. Epub 2014 Mar 18. Review.

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