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Items: 1 to 50 of 503

1.

Clinically amelanotic or hypomelanotic melanoma: Anatomic distribution, risk factors, and survival.

Wee E, Wolfe R, Mclean C, Kelly JW, Pan Y.

J Am Acad Dermatol. 2018 Oct;79(4):645-651.e4. doi: 10.1016/j.jaad.2018.04.045.

PMID:
30241625
2.

Dermoscopy improves diagnostic accuracy for clinically amelanotic nodules.

Lin MJ, Xie C, Pan Y, Jalilian C, Kelly JW.

Australas J Dermatol. 2018 Aug 19. doi: 10.1111/ajd.12902. [Epub ahead of print]

PMID:
30123971
3.

Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins.

Paxman R, Plate L, Blackwood EA, Glembotski C, Powers ET, Wiseman RL, Kelly JW.

Elife. 2018 Aug 7;7. pii: e37168. doi: 10.7554/eLife.37168.

4.

Cellular clearance of circulating transthyretin decreases cell-nonautonomous proteotoxicity in Caenorhabditis elegans.

Madhivanan K, Greiner ER, Alves-Ferreira M, Soriano-Castell D, Rouzbeh N, Aguirre CA, Paulsson JF, Chapman J, Jiang X, Ooi FK, Lemos C, Dillin A, Prahlad V, Kelly JW, Encalada SE.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7710-E7719. doi: 10.1073/pnas.1801117115. Epub 2018 Jul 30.

PMID:
30061394
5.

Crowdsourcing image analysis for plant phenomics to generate ground truth data for machine learning.

Zhou N, Siegel ZD, Zarecor S, Lee N, Campbell DA, Andorf CM, Nettleton D, Lawrence-Dill CJ, Ganapathysubramanian B, Kelly JW, Friedberg I.

PLoS Comput Biol. 2018 Jul 30;14(7):e1006337. doi: 10.1371/journal.pcbi.1006337. eCollection 2018 Jul.

6.

Cerebrospinal fluid and vitreous body exposure to orally administered tafamidis in hereditary ATTRV30M (p.TTRV50M) amyloidosis patients.

Monteiro C, Martins da Silva A, Ferreira N, Mesgarzadeh J, Novais M, Coelho T, Kelly JW.

Amyloid. 2018 Jul 11:1-9. doi: 10.1080/13506129.2018.1479249. [Epub ahead of print]

PMID:
29993288
7.

The two shapes of the Tau protein.

Kelly JW.

Elife. 2018 Jul 10;7. pii: e38516. doi: 10.7554/eLife.38516.

8.

NMR Measurements Reveal the Structural Basis of Transthyretin Destabilization by Pathogenic Mutations.

Leach BI, Zhang X, Kelly JW, Dyson HJ, Wright PE.

Biochemistry. 2018 Jul 31;57(30):4421-4430. doi: 10.1021/acs.biochem.8b00642. Epub 2018 Jul 18.

PMID:
29972637
9.

Selection of macroreference frames in spatial memory.

Kelly JW, Siegel ZD, Sjolund LA, Avraamides MN.

Mem Cognit. 2018 Jun 21. doi: 10.3758/s13421-018-0836-2. [Epub ahead of print]

PMID:
29931620
10.

Deducing the presence of proteins and proteoforms in quantitative proteomics.

Bamberger C, Martínez-Bartolomé S, Montgomery M, Pankow S, Hulleman JD, Kelly JW, Yates JR 3rd.

Nat Commun. 2018 Jun 13;9(1):2320. doi: 10.1038/s41467-018-04411-5.

11.

Tumour mutation status and melanoma recurrence following a negative sentinel lymph node biopsy.

Adler NR, Wolfe R, McArthur GA, Kelly JW, Haydon A, McLean CA, Mar VJ.

Br J Cancer. 2018 May;118(10):1289-1295. doi: 10.1038/s41416-018-0088-8. Epub 2018 May 14.

PMID:
29755118
12.

Mechanism of Action of the Cytotoxic Asmarine Alkaloids.

Lambrecht MJ, Kelly JW, Shenvi RA.

ACS Chem Biol. 2018 May 18;13(5):1299-1306. doi: 10.1021/acschembio.8b00096. Epub 2018 Apr 19.

PMID:
29653046
13.

Concordance of somatic mutational profile in multiple primary melanomas.

Adler NR, McLean CA, Wolfe R, Kelly JW, McArthur GA, Haydon A, Tra T, Cummings N, Mar VJ.

Pigment Cell Melanoma Res. 2018 Mar 30. doi: 10.1111/pcmr.12702. [Epub ahead of print]

PMID:
29603877
14.

Impact of naevus association on survival for nodular and superficial spreading melanomas.

Vu M, Adler NR, Wee E, Wolfe R, McLean CA, Kelly JW, Pan Y.

Br J Dermatol. 2018 Sep;179(3):761-762. doi: 10.1111/bjd.16556. Epub 2018 Jun 21. No abstract available.

PMID:
29573395
15.
16.

The unfolded protein response regulator ATF6 promotes mesodermal differentiation.

Kroeger H, Grimsey N, Paxman R, Chiang WC, Plate L, Jones Y, Shaw PX, Trejo J, Tsang SH, Powers E, Kelly JW, Wiseman RL, Lin JH.

Sci Signal. 2018 Feb 13;11(517). pii: eaan5785. doi: 10.1126/scisignal.aan5785.

17.

Social effects on reference frame selection.

Kelly JW, Costabile KA, Cherep LA.

Psychon Bull Rev. 2018 Jan 23. doi: 10.3758/s13423-018-1429-6. [Epub ahead of print]

PMID:
29363061
18.

An unusual onset of agminated Spitz naevi in an adult patient.

Adler NR, Kelly JW, Dowling JP, Saunders H, Mar VJ.

Clin Exp Dermatol. 2018 Apr;43(3):363-365. doi: 10.1111/ced.13343. Epub 2017 Dec 20. No abstract available.

PMID:
29266351
19.

"Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates.

Mortenson DE, Brighty GJ, Plate L, Bare G, Chen W, Li S, Wang H, Cravatt BF, Forli S, Powers ET, Sharpless KB, Wilson IA, Kelly JW.

J Am Chem Soc. 2018 Jan 10;140(1):200-210. doi: 10.1021/jacs.7b08366. Epub 2017 Dec 21.

PMID:
29265822
20.

Age-dependent cognitive dysfunction in untreated hereditary transthyretin amyloidosis.

Martins da Silva A, Cavaco S, Fernandes J, Samões R, Alves C, Cardoso M, Kelly JW, Monteiro C, Coelho T.

J Neurol. 2018 Feb;265(2):299-307. doi: 10.1007/s00415-017-8668-8. Epub 2017 Dec 5.

PMID:
29209781
21.

Incomplete Refolding of Antibody Light Chains to Non-Native, Protease-Sensitive Conformations Leads to Aggregation: A Mechanism of Amyloidogenesis in Patients?

Morgan GJ, Usher GA, Kelly JW.

Biochemistry. 2017 Dec 19;56(50):6597-6614. doi: 10.1021/acs.biochem.7b00579. Epub 2017 Dec 4.

PMID:
29200282
22.

Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology.

Savas JN, Wang YZ, DeNardo LA, Martinez-Bartolome S, McClatchy DB, Hark TJ, Shanks NF, Cozzolino KA, Lavallée-Adam M, Smukowski SN, Park SK, Kelly JW, Koo EH, Nakagawa T, Masliah E, Ghosh A, Yates JR 3rd.

Cell Rep. 2017 Nov 28;21(9):2614-2627. doi: 10.1016/j.celrep.2017.11.009.

23.

Translation efficiency is maintained at elevated temperature in Escherichia coli.

Morgan GJ, Burkhardt DH, Kelly JW, Powers ET.

J Biol Chem. 2018 Jan 19;293(3):777-793. doi: 10.1074/jbc.RA117.000284. Epub 2017 Nov 28.

PMID:
29183994
24.

A novel clinical sign to aid in the diagnosis of superficial basal cell carcinoma.

Adler NR, Pan Y, Kelly JW.

J Am Acad Dermatol. 2017 Dec;77(6):e155-e156. doi: 10.1016/j.jaad.2017.05.054. No abstract available.

PMID:
29132860
25.

Nodular melanoma is less likely than superficial spreading melanoma to be histologically associated with a naevus.

Pan Y, Adler NR, Wolfe R, McLean CA, Kelly JW.

Med J Aust. 2017 Oct 16;207(8):333-338.

PMID:
29020904
26.

Clinical practice guidelines for the diagnosis and management of melanoma: melanomas that lack classical clinical features.

Mar VJ, Chamberlain AJ, Kelly JW, Murray WK, Thompson JF.

Med J Aust. 2017 Oct 16;207(8):348-350.

PMID:
29020893
27.

Rescaling of perceived space transfers across virtual environments.

Siegel ZD, Kelly JW, Cherep LA.

J Exp Psychol Hum Percept Perform. 2017 Oct;43(10):1805-1814. doi: 10.1037/xhp0000401.

PMID:
28967784
28.

Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients.

Schonhoft JD, Monteiro C, Plate L, Eisele YS, Kelly JM, Boland D, Parker CG, Cravatt BF, Teruya S, Helmke S, Maurer M, Berk J, Sekijima Y, Novais M, Coelho T, Powers ET, Kelly JW.

Sci Transl Med. 2017 Sep 13;9(407). pii: eaam7621. doi: 10.1126/scitranslmed.aam7621.

29.

Optimal combination of environmental cues and path integration during navigation.

Sjolund LA, Kelly JW, McNamara TP.

Mem Cognit. 2018 Jan;46(1):89-99. doi: 10.3758/s13421-017-0747-7.

PMID:
28828745
30.

Pathogenic Mutations Induce Partial Structural Changes in the Native β-Sheet Structure of Transthyretin and Accelerate Aggregation.

Lim KH, Dasari AKR, Ma R, Hung I, Gan Z, Kelly JW, Fitzgerald MC.

Biochemistry. 2017 Sep 12;56(36):4808-4818. doi: 10.1021/acs.biochem.7b00658. Epub 2017 Aug 30.

31.

Residues Comprising the Enhanced Aromatic Sequon Influence Protein N-Glycosylation Efficiency.

Huang YW, Yang HI, Wu YT, Hsu TL, Lin TW, Kelly JW, Wong CH.

J Am Chem Soc. 2017 Sep 20;139(37):12947-12955. doi: 10.1021/jacs.7b03868. Epub 2017 Sep 6.

PMID:
28820257
32.

Tumour mutation status and sites of metastasis in patients with cutaneous melanoma.

Adler NR, Wolfe R, Kelly JW, Haydon A, McArthur GA, McLean CA, Mar VJ.

Br J Cancer. 2017 Sep 26;117(7):1026-1035. doi: 10.1038/bjc.2017.254. Epub 2017 Aug 8.

33.

Clinicopathological characteristics and prognosis of patients with multiple primary melanomas.

Adler NR, Kelly JW, Haydon A, McLean CA, Mar VJ.

Br J Dermatol. 2018 Jan;178(1):e44-e45. doi: 10.1111/bjd.15855. Epub 2017 Dec 29. No abstract available.

PMID:
28755438
34.

Reference frames in spatial updating when body-based cues are absent.

He Q, McNamara TP, Kelly JW.

Mem Cognit. 2018 Jan;46(1):32-42. doi: 10.3758/s13421-017-0743-y.

PMID:
28755051
35.

Using Cooperatively Folded Peptides To Measure Interaction Energies and Conformational Propensities.

Ardejani MS, Powers ET, Kelly JW.

Acc Chem Res. 2017 Aug 15;50(8):1875-1882. doi: 10.1021/acs.accounts.7b00195. Epub 2017 Jul 19.

36.

The endoplasmic reticulum HSP40 co-chaperone ERdj3/DNAJB11 assembles and functions as a tetramer.

Chen KC, Qu S, Chowdhury S, Noxon IC, Schonhoft JD, Plate L, Powers ET, Kelly JW, Lander GC, Wiseman RL.

EMBO J. 2017 Aug 1;36(15):2296-2309. doi: 10.15252/embj.201695616. Epub 2017 Jun 27.

37.

Semi-quantitative models for identifying potent and selective transthyretin amyloidogenesis inhibitors.

Connelly S, Mortenson DE, Choi S, Wilson IA, Powers ET, Kelly JW, Johnson SM.

Bioorg Med Chem Lett. 2017 Aug 1;27(15):3441-3449. doi: 10.1016/j.bmcl.2017.05.080. Epub 2017 May 26.

38.

Cue combination in human spatial navigation.

Chen X, McNamara TP, Kelly JW, Wolbers T.

Cogn Psychol. 2017 Jun;95:105-144. doi: 10.1016/j.cogpsych.2017.04.003. Epub 2017 May 4.

PMID:
28478330
39.

An ortho-Iminoquinone Compound Reacts with Lysine Inhibiting Aggregation while Remodeling Mature Amyloid Fibrils.

Fernandes L, Moraes N, Sagrillo FS, Magalhães AV, de Moraes MC, Romão L, Kelly JW, Foguel D, Grimster NP, Palhano FL.

ACS Chem Neurosci. 2017 Aug 16;8(8):1704-1712. doi: 10.1021/acschemneuro.7b00017. Epub 2017 May 4.

PMID:
28425704
40.

Regulated in Development and DNA Damage Response 1 Deficiency Impairs Autophagy and Mitochondrial Biogenesis in Articular Cartilage and Increases the Severity of Experimental Osteoarthritis.

Alvarez-Garcia O, Matsuzaki T, Olmer M, Plate L, Kelly JW, Lotz MK.

Arthritis Rheumatol. 2017 Jul;69(7):1418-1428. doi: 10.1002/art.40104. Epub 2017 Jun 2.

41.

Walking through a virtual environment improves perceived size within and beyond the walked space.

Siegel ZD, Kelly JW.

Atten Percept Psychophys. 2017 Jan;79(1):39-44. doi: 10.3758/s13414-016-1243-z.

PMID:
27914094
42.

Response to Letter Regarding Manuscript "Electronic Hand Hygiene Monitoring as a Tool for Reducing Nosocomial Methicillin-resistant Staphylococcus aureus Infection".

Kelly JW, Blackhurst D, McAtee W, Steed C.

Am J Infect Control. 2016 Dec 1;44(12):1763. doi: 10.1016/j.ajic.2016.08.009. No abstract available.

PMID:
27908437
43.

Metastatic pathways in patients with cutaneous melanoma.

Adler NR, Haydon A, McLean CA, Kelly JW, Mar VJ.

Pigment Cell Melanoma Res. 2017 Jan;30(1):13-27. doi: 10.1111/pcmr.12544. Epub 2016 Nov 30. Review.

PMID:
27900851
44.

Endoplasmic Reticulum Proteostasis Influences the Oligomeric State of an Amyloidogenic Protein Secreted from Mammalian Cells.

Chen JJ, Genereux JC, Suh EH, Vartabedian VF, Rius B, Qu S, Dendle MTA, Kelly JW, Wiseman RL.

Cell Chem Biol. 2016 Oct 20;23(10):1282-1293. doi: 10.1016/j.chembiol.2016.09.001. Epub 2016 Oct 6.

45.

Solid-State NMR Studies Reveal Native-like β-Sheet Structures in Transthyretin Amyloid.

Lim KH, Dasari AK, Hung I, Gan Z, Kelly JW, Wright PE, Wemmer DE.

Biochemistry. 2016 Sep 20;55(37):5272-8. doi: 10.1021/acs.biochem.6b00649. Epub 2016 Sep 7.

46.

Peripheral Blood Cell Gene Expression Diagnostic for Identifying Symptomatic Transthyretin Amyloidosis Patients: Male and Female Specific Signatures.

Kurian SM, Novais M, Whisenant T, Gelbart T, Buxbaum JN, Kelly JW, Coelho T, Salomon DR.

Theranostics. 2016 Jul 18;6(11):1792-809. doi: 10.7150/thno.14584. eCollection 2016.

47.

The Kinetic Stability of a Full-Length Antibody Light Chain Dimer Determines whether Endoproteolysis Can Release Amyloidogenic Variable Domains.

Morgan GJ, Kelly JW.

J Mol Biol. 2016 Oct 23;428(21):4280-4297. doi: 10.1016/j.jmb.2016.08.021. Epub 2016 Aug 26.

48.

Small molecule proteostasis regulators that reprogram the ER to reduce extracellular protein aggregation.

Plate L, Cooley CB, Chen JJ, Paxman RJ, Gallagher CM, Madoux F, Genereux JC, Dobbs W, Garza D, Spicer TP, Scampavia L, Brown SJ, Rosen H, Powers ET, Walter P, Hodder P, Wiseman RL, Kelly JW.

Elife. 2016 Jul 20;5. pii: e15550. doi: 10.7554/eLife.15550.

49.

Modulating protein quality control.

Plate L, Paxman RJ, Wiseman RL, Kelly JW.

Elife. 2016 Jul 20;5. pii: e18431. doi: 10.7554/eLife.18431.

50.

Electronic hand hygiene monitoring as a tool for reducing health care-associated methicillin-resistant Staphylococcus aureus infection.

Kelly JW, Blackhurst D, McAtee W, Steed C.

Am J Infect Control. 2016 Aug 1;44(8):956-7. doi: 10.1016/j.ajic.2016.04.215. Epub 2016 Jun 23.

PMID:
27346800

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