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Acral lentiginous melanoma: differences in survival compared with other subtypes.

Howard MD, Xie C, Wee E, Wolfe R, McLean CA, Kelly JW, Pan Y.

Br J Dermatol. 2019 Oct 19. doi: 10.1111/bjd.18620. [Epub ahead of print] No abstract available.


The Role of Protein Thermodynamics and Primary Structure in Fibrillogenesis of Variable Domains from Immunoglobulin Light Chains.

Rennella E, Morgan GJ, Yan N, Kelly JW, Kay LE.

J Am Chem Soc. 2019 Aug 28;141(34):13562-13571. doi: 10.1021/jacs.9b05499. Epub 2019 Aug 14.


The increasing use of shave biopsy for diagnosing invasive melanoma in Australia.

de Menezes SL, Kelly JW, Wolfe R, Farrugia H, Mar VJ.

Med J Aust. 2019 Sep;211(5):213-218. doi: 10.5694/mja2.50289. Epub 2019 Jul 22.


Differences between pure desmoplastic melanoma and superficial spreading melanoma in terms of survival, distribution and other clinicopathologic features.

Howard MD, Wee E, Wolfe R, McLean CA, Kelly JW, Pan Y.

J Eur Acad Dermatol Venereol. 2019 Oct;33(10):1899-1906. doi: 10.1111/jdv.15759. Epub 2019 Jul 22.


Improving diagnostic accuracy for suspicious melanocytic skin lesions: New Australian melanoma clinical practice guidelines stress the importance of clinician/pathologist communication.

Scolyer RA, Soyer HP, Kelly JW, James C, McLean CA, Coventry BJ, Ferguson PM, Rawson RV, Mar VJ, de Menezes SL, Fishburn P, Stretch JR, Lee S, Thompson JF.

Aust J Gen Pract. 2019 Jun;48(6):357-362. doi: 10.31128/AJGP-11-18-4759.


Predictive model of response to tafamidis in hereditary ATTR polyneuropathy.

Monteiro C, Mesgazardeh JS, Anselmo J, Fernandes J, Novais M, Rodrigues C, Brighty GJ, Powers DL, Powers ET, Coelho T, Kelly JW.

JCI Insight. 2019 Jun 20;4(12). pii: 126526. doi: 10.1172/jci.insight.126526. eCollection 2019 Jun 20.


Transthyretin Amyloid Cardiomyopathy: JACC State-of-the-Art Review.

Ruberg FL, Grogan M, Hanna M, Kelly JW, Maurer MS.

J Am Coll Cardiol. 2019 Jun 11;73(22):2872-2891. doi: 10.1016/j.jacc.2019.04.003. Review.


Quantitative Interactome Proteomics Reveals a Molecular Basis for ATF6-Dependent Regulation of a Destabilized Amyloidogenic Protein.

Plate L, Rius B, Nguyen B, Genereux JC, Kelly JW, Wiseman RL.

Cell Chem Biol. 2019 Jul 18;26(7):913-925.e4. doi: 10.1016/j.chembiol.2019.04.001. Epub 2019 May 16.


Pharmacologic Approaches for Adapting Proteostasis in the Secretory Pathway to Ameliorate Protein Conformational Diseases.

Kelly JW.

Cold Spring Harb Perspect Biol. 2019 May 14. pii: a034108. doi: 10.1101/cshperspect.a034108. [Epub ahead of print]


Anatomic location of primary melanoma: Survival differences and sun exposure.

Howard MD, Wee E, Wolfe R, McLean CA, Kelly JW, Pan Y.

J Am Acad Dermatol. 2019 Aug;81(2):500-509. doi: 10.1016/j.jaad.2019.04.034. Epub 2019 Apr 19.


Stabilization of amyloidogenic immunoglobulin light chains by small molecules.

Morgan GJ, Yan NL, Mortenson DE, Rennella E, Blundon JM, Gwin RM, Lin CY, Stanfield RL, Brown SJ, Rosen H, Spicer TP, Fernandez-Vega V, Merlini G, Kay LE, Wilson IA, Kelly JW.

Proc Natl Acad Sci U S A. 2019 Apr 23;116(17):8360-8369. doi: 10.1073/pnas.1817567116. Epub 2019 Apr 10.


Accuracy of partial biopsies in the management of cutaneous melanoma.

Doolan BJ, Robinson AJ, Wolfe R, Kelly JW, McLean C, McCormack C, Henderson MA, Pan Y.

Australas J Dermatol. 2019 Aug;60(3):209-213. doi: 10.1111/ajd.13004. Epub 2019 Feb 17.


Pharmacologic ATF6 activation confers global protection in widespread disease models by reprograming cellular proteostasis.

Blackwood EA, Azizi K, Thuerauf DJ, Paxman RJ, Plate L, Kelly JW, Wiseman RL, Glembotski CC.

Nat Commun. 2019 Jan 14;10(1):187. doi: 10.1038/s41467-018-08129-2.


Methods of melanoma detection and of skin monitoring for individuals at high risk of melanoma: new Australian clinical practice.

Adler NR, Kelly JW, Guitera P, Menzies SW, Chamberlain AJ, Fishburn P, Button-Sloan AE, Heal C, Soyer HP, Thompson JF.

Med J Aust. 2019 Jan;210(1):41-47. doi: 10.5694/mja2.12033. Epub 2018 Dec 2.


Transthyretin Aggregation Pathway toward the Formation of Distinct Cytotoxic Oligomers.

Dasari AKR, Hughes RM, Wi S, Hung I, Gan Z, Kelly JW, Lim KH.

Sci Rep. 2019 Jan 10;9(1):33. doi: 10.1038/s41598-018-37230-1.


Correction to "Mispacking of the Phe87 Side Chain Reduces the Kinetic Stability of Human Transthyretin".

Sun X, Jaeger M, Kelly JW, Dyson HJ, Wright PE.

Biochemistry. 2019 Feb 12;58(6):858. doi: 10.1021/acs.biochem.8b01312. Epub 2019 Jan 7. No abstract available.


Role of domain interactions in the aggregation of full-length immunoglobulin light chains.

Rennella E, Morgan GJ, Kelly JW, Kay LE.

Proc Natl Acad Sci U S A. 2019 Jan 15;116(3):854-863. doi: 10.1073/pnas.1817538116. Epub 2018 Dec 31.


Acclimation and adaptation components of the temperature dependence of plant photosynthesis at the global scale.

Kumarathunge DP, Medlyn BE, Drake JE, Tjoelker MG, Aspinwall MJ, Battaglia M, Cano FJ, Carter KR, Cavaleri MA, Cernusak LA, Chambers JQ, Crous KY, De Kauwe MG, Dillaway DN, Dreyer E, Ellsworth DS, Ghannoum O, Han Q, Hikosaka K, Jensen AM, Kelly JWG, Kruger EL, Mercado LM, Onoda Y, Reich PB, Rogers A, Slot M, Smith NG, Tarvainen L, Tissue DT, Togashi HF, Tribuzy ES, Uddling J, Vårhammar A, Wallin G, Warren JM, Way DA.

New Phytol. 2019 Apr;222(2):768-784. doi: 10.1111/nph.15668. Epub 2019 Feb 8.


Mispacking of the Phe87 Side Chain Reduces the Kinetic Stability of Human Transthyretin.

Sun X, Jaeger M, Kelly JW, Dyson HJ, Wright PE.

Biochemistry. 2018 Dec 26;57(51):6919-6922. doi: 10.1021/acs.biochem.8b01046. Epub 2018 Dec 14. Erratum in: Biochemistry. 2019 Feb 12;58(6):858.


A designed protein binding-pocket to control excited-state intramolecular proton transfer fluorescence.

Lampkin BJ, Monteiro C, Powers ET, Bouc PM, Kelly JW, VanVeller B.

Org Biomol Chem. 2019 Jan 31;17(5):1076-1080. doi: 10.1039/c8ob02673d.


Tenosynovial and Cardiac Amyloidosis in Patients Undergoing Carpal Tunnel Release.

Sperry BW, Reyes BA, Ikram A, Donnelly JP, Phelan D, Jaber WA, Shapiro D, Evans PJ, Maschke S, Kilpatrick SE, Tan CD, Rodriguez ER, Monteiro C, Tang WHW, Kelly JW, Seitz WH Jr, Hanna M.

J Am Coll Cardiol. 2018 Oct 23;72(17):2040-2050. doi: 10.1016/j.jacc.2018.07.092.


Clinically amelanotic or hypomelanotic melanoma: Anatomic distribution, risk factors, and survival.

Wee E, Wolfe R, Mclean C, Kelly JW, Pan Y.

J Am Acad Dermatol. 2018 Oct;79(4):645-651.e4. doi: 10.1016/j.jaad.2018.04.045.


Dermoscopy improves diagnostic accuracy for clinically amelanotic nodules.

Lin MJ, Xie C, Pan Y, Jalilian C, Kelly JW.

Australas J Dermatol. 2019 Feb;60(1):45-49. doi: 10.1111/ajd.12902. Epub 2018 Aug 19.


Pharmacologic ATF6 activating compounds are metabolically activated to selectively modify endoplasmic reticulum proteins.

Paxman R, Plate L, Blackwood EA, Glembotski C, Powers ET, Wiseman RL, Kelly JW.

Elife. 2018 Aug 7;7. pii: e37168. doi: 10.7554/eLife.37168.


Cellular clearance of circulating transthyretin decreases cell-nonautonomous proteotoxicity in Caenorhabditis elegans.

Madhivanan K, Greiner ER, Alves-Ferreira M, Soriano-Castell D, Rouzbeh N, Aguirre CA, Paulsson JF, Chapman J, Jiang X, Ooi FK, Lemos C, Dillin A, Prahlad V, Kelly JW, Encalada SE.

Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):E7710-E7719. doi: 10.1073/pnas.1801117115. Epub 2018 Jul 30. Erratum in: Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3338.


Crowdsourcing image analysis for plant phenomics to generate ground truth data for machine learning.

Zhou N, Siegel ZD, Zarecor S, Lee N, Campbell DA, Andorf CM, Nettleton D, Lawrence-Dill CJ, Ganapathysubramanian B, Kelly JW, Friedberg I.

PLoS Comput Biol. 2018 Jul 30;14(7):e1006337. doi: 10.1371/journal.pcbi.1006337. eCollection 2018 Jul.


Cerebrospinal fluid and vitreous body exposure to orally administered tafamidis in hereditary ATTRV30M (p.TTRV50M) amyloidosis patients.

Monteiro C, Martins da Silva A, Ferreira N, Mesgarzadeh J, Novais M, Coelho T, Kelly JW.

Amyloid. 2018 Jun;25(2):120-128. doi: 10.1080/13506129.2018.1479249. Epub 2018 Jul 11.


The two shapes of the Tau protein.

Kelly JW.

Elife. 2018 Jul 10;7. pii: e38516. doi: 10.7554/eLife.38516.


NMR Measurements Reveal the Structural Basis of Transthyretin Destabilization by Pathogenic Mutations.

Leach BI, Zhang X, Kelly JW, Dyson HJ, Wright PE.

Biochemistry. 2018 Jul 31;57(30):4421-4430. doi: 10.1021/acs.biochem.8b00642. Epub 2018 Jul 18.


Selection of macroreference frames in spatial memory.

Kelly JW, Siegel ZD, Sjolund LA, Avraamides MN.

Mem Cognit. 2018 Nov;46(8):1278-1286. doi: 10.3758/s13421-018-0836-2.


Deducing the presence of proteins and proteoforms in quantitative proteomics.

Bamberger C, Martínez-Bartolomé S, Montgomery M, Pankow S, Hulleman JD, Kelly JW, Yates JR 3rd.

Nat Commun. 2018 Jun 13;9(1):2320. doi: 10.1038/s41467-018-04411-5.


Tumour mutation status and melanoma recurrence following a negative sentinel lymph node biopsy.

Adler NR, Wolfe R, McArthur GA, Kelly JW, Haydon A, McLean CA, Mar VJ.

Br J Cancer. 2018 May;118(10):1289-1295. doi: 10.1038/s41416-018-0088-8. Epub 2018 May 14.


Mechanism of Action of the Cytotoxic Asmarine Alkaloids.

Lambrecht MJ, Kelly JW, Shenvi RA.

ACS Chem Biol. 2018 May 18;13(5):1299-1306. doi: 10.1021/acschembio.8b00096. Epub 2018 Apr 19.


Concordance of somatic mutational profile in multiple primary melanomas.

Adler NR, McLean CA, Wolfe R, Kelly JW, McArthur GA, Haydon A, Tra T, Cummings N, Mar VJ.

Pigment Cell Melanoma Res. 2018 Sep;31(5):592-603. doi: 10.1111/pcmr.12702. Epub 2018 Apr 15.


Impact of naevus association on survival for nodular and superficial spreading melanomas.

Vu M, Adler NR, Wee E, Wolfe R, McLean CA, Kelly JW, Pan Y.

Br J Dermatol. 2018 Sep;179(3):761-762. doi: 10.1111/bjd.16556. Epub 2018 Jun 21. No abstract available.


You should get that mole checked out: Ethical and legal considerations of the unsolicited clinical opinion.

Adler NR, Mahar PD, Kelly JW.

Aust Fam Physician. 2017 Dec;46(12):949-951. Review.


The unfolded protein response regulator ATF6 promotes mesodermal differentiation.

Kroeger H, Grimsey N, Paxman R, Chiang WC, Plate L, Jones Y, Shaw PX, Trejo J, Tsang SH, Powers E, Kelly JW, Wiseman RL, Lin JH.

Sci Signal. 2018 Feb 13;11(517). pii: eaan5785. doi: 10.1126/scisignal.aan5785.


Social effects on reference frame selection.

Kelly JW, Costabile KA, Cherep LA.

Psychon Bull Rev. 2018 Dec;25(6):2339-2345. doi: 10.3758/s13423-018-1429-6.


An unusual onset of agminated Spitz naevi in an adult patient.

Adler NR, Kelly JW, Dowling JP, Saunders H, Mar VJ.

Clin Exp Dermatol. 2018 Apr;43(3):363-365. doi: 10.1111/ced.13343. Epub 2017 Dec 20. No abstract available.


"Inverse Drug Discovery" Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates.

Mortenson DE, Brighty GJ, Plate L, Bare G, Chen W, Li S, Wang H, Cravatt BF, Forli S, Powers ET, Sharpless KB, Wilson IA, Kelly JW.

J Am Chem Soc. 2018 Jan 10;140(1):200-210. doi: 10.1021/jacs.7b08366. Epub 2017 Dec 21.


Age-dependent cognitive dysfunction in untreated hereditary transthyretin amyloidosis.

Martins da Silva A, Cavaco S, Fernandes J, Samões R, Alves C, Cardoso M, Kelly JW, Monteiro C, Coelho T.

J Neurol. 2018 Feb;265(2):299-307. doi: 10.1007/s00415-017-8668-8. Epub 2017 Dec 5.


Incomplete Refolding of Antibody Light Chains to Non-Native, Protease-Sensitive Conformations Leads to Aggregation: A Mechanism of Amyloidogenesis in Patients?

Morgan GJ, Usher GA, Kelly JW.

Biochemistry. 2017 Dec 19;56(50):6597-6614. doi: 10.1021/acs.biochem.7b00579. Epub 2017 Dec 4.


Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer's Disease-like Pathology.

Savas JN, Wang YZ, DeNardo LA, Martinez-Bartolome S, McClatchy DB, Hark TJ, Shanks NF, Cozzolino KA, Lavallée-Adam M, Smukowski SN, Park SK, Kelly JW, Koo EH, Nakagawa T, Masliah E, Ghosh A, Yates JR 3rd.

Cell Rep. 2017 Nov 28;21(9):2614-2627. doi: 10.1016/j.celrep.2017.11.009.


Translation efficiency is maintained at elevated temperature in Escherichia coli.

Morgan GJ, Burkhardt DH, Kelly JW, Powers ET.

J Biol Chem. 2018 Jan 19;293(3):777-793. doi: 10.1074/jbc.RA117.000284. Epub 2017 Nov 28.


A novel clinical sign to aid in the diagnosis of superficial basal cell carcinoma.

Adler NR, Pan Y, Kelly JW.

J Am Acad Dermatol. 2017 Dec;77(6):e155-e156. doi: 10.1016/j.jaad.2017.05.054. No abstract available.


Nodular melanoma is less likely than superficial spreading melanoma to be histologically associated with a naevus.

Pan Y, Adler NR, Wolfe R, McLean CA, Kelly JW.

Med J Aust. 2017 Oct 16;207(8):333-338.


Clinical practice guidelines for the diagnosis and management of melanoma: melanomas that lack classical clinical features.

Mar VJ, Chamberlain AJ, Kelly JW, Murray WK, Thompson JF.

Med J Aust. 2017 Oct 16;207(8):348-350.


Rescaling of perceived space transfers across virtual environments.

Siegel ZD, Kelly JW, Cherep LA.

J Exp Psychol Hum Percept Perform. 2017 Oct;43(10):1805-1814. doi: 10.1037/xhp0000401.


Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients.

Schonhoft JD, Monteiro C, Plate L, Eisele YS, Kelly JM, Boland D, Parker CG, Cravatt BF, Teruya S, Helmke S, Maurer M, Berk J, Sekijima Y, Novais M, Coelho T, Powers ET, Kelly JW.

Sci Transl Med. 2017 Sep 13;9(407). pii: eaam7621. doi: 10.1126/scitranslmed.aam7621.


Optimal combination of environmental cues and path integration during navigation.

Sjolund LA, Kelly JW, McNamara TP.

Mem Cognit. 2018 Jan;46(1):89-99. doi: 10.3758/s13421-017-0747-7.


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