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Items: 1 to 50 of 134

1.

Tissue Chips in Space-Challenges and Opportunities.

Yeung CK, Koenig P, Countryman S, Thummel KE, Himmelfarb J, Kelly EJ.

Clin Transl Sci. 2019 Sep 16. doi: 10.1111/cts.12689. [Epub ahead of print] No abstract available.

PMID:
31524321
2.

Mechanisms of CYP3A Induction During Pregnancy: Studies in HepaRG Cells.

Sachar M, Kelly EJ, Unadkat JD.

AAPS J. 2019 Mar 27;21(3):45. doi: 10.1208/s12248-019-0316-z.

PMID:
30919109
3.

Translational Assessment of Drug-Induced Proximal Tubule Injury Using a Kidney Microphysiological System.

Maass C, Sorensen NB, Himmelfarb J, Kelly EJ, Stokes CL, Cirit M.

CPT Pharmacometrics Syst Pharmacol. 2019 May;8(5):316-325. doi: 10.1002/psp4.12400. Epub 2019 Apr 9.

4.

Human kidney on a chip assessment of polymyxin antibiotic nephrotoxicity.

Weber EJ, Lidberg KA, Wang L, Bammler TK, MacDonald JW, Li MJ, Redhair M, Atkins WM, Tran C, Hines KM, Herron J, Xu L, Monteiro MB, Ramm S, Vaidya V, Vaara M, Vaara T, Himmelfarb J, Kelly EJ.

JCI Insight. 2018 Dec 20;3(24). pii: 123673. doi: 10.1172/jci.insight.123673.

5.

Reconstructing the Human Renal Vascular-Tubular Unit In Vitro.

Rayner SG, Phong KT, Xue J, Lih D, Shankland SJ, Kelly EJ, Himmelfarb J, Zheng Y.

Adv Healthc Mater. 2018 Dec;7(23):e1801120. doi: 10.1002/adhm.201801120. Epub 2018 Oct 31.

PMID:
30379416
6.

A High-Throughput Screen Identifies DYRK1A Inhibitor ID-8 that Stimulates Human Kidney Tubular Epithelial Cell Proliferation.

Monteiro MB, Ramm S, Chandrasekaran V, Boswell SA, Weber EJ, Lidberg KA, Kelly EJ, Vaidya VS.

J Am Soc Nephrol. 2018 Dec;29(12):2820-2833. doi: 10.1681/ASN.2018040392. Epub 2018 Oct 25.

PMID:
30361326
7.

Technology Transfer of the Microphysiological Systems: A Case Study of the Human Proximal Tubule Tissue Chip.

Sakolish C, Weber EJ, Kelly EJ, Himmelfarb J, Mouneimne R, Grimm FA, House JS, Wade T, Han A, Chiu WA, Rusyn I.

Sci Rep. 2018 Oct 5;8(1):14882. doi: 10.1038/s41598-018-33099-2.

8.

Emerging Kidney Models to Investigate Metabolism, Transport, and Toxicity of Drugs and Xenobiotics.

Bajaj P, Chowdhury SK, Yucha R, Kelly EJ, Xiao G.

Drug Metab Dispos. 2018 Nov;46(11):1692-1702. doi: 10.1124/dmd.118.082958. Epub 2018 Aug 3. Review.

PMID:
30076203
9.

Reevaluating the role of megalin in renal vitamin D homeostasis using a human cell-derived microphysiological system

Chapron BD, Chapron A, Phillips B, Okoli MC, Shen DD, Kelly EJ, Himmelfarb J, Thummel KE.

ALTEX. 2018;35(4):504-515. doi: 10.14573/altex.1803161. Epub 2018 Jul 8.

10.

HAEMOPROTEUS ( PARAHAEMOPROTEUS) SPP. IN CAPTIVE-BRED BOBWHITE QUAIL ( COLINUS VIRGINIANUS) IN SOUTHERN UTAH, USA.

Kelly EJ, Baldwin TJ, Frame DD, Childress AL, Wellehan JFX.

J Wildl Dis. 2018 Oct;54(4):726-733. doi: 10.7589/2017-01-014. Epub 2018 May 9.

PMID:
29742000
11.

Human liver-kidney model elucidates the mechanisms of aristolochic acid nephrotoxicity.

Chang SY, Weber EJ, Sidorenko VS, Chapron A, Yeung CK, Gao C, Mao Q, Shen D, Wang J, Rosenquist TA, Dickman KG, Neumann T, Grollman AP, Kelly EJ, Himmelfarb J, Eaton DL.

JCI Insight. 2017 Nov 16;2(22). pii: 95978. doi: 10.1172/jci.insight.95978. eCollection 2017 Nov 16.

12.

Transporter Expression in Noncancerous and Cancerous Liver Tissue from Donors with Hepatocellular Carcinoma and Chronic Hepatitis C Infection Quantified by LC-MS/MS Proteomics.

Billington S, Ray AS, Salphati L, Xiao G, Chu X, Humphreys WG, Liao M, Lee CA, Mathias A, Hop CECA, Rowbottom C, Evers R, Lai Y, Kelly EJ, Prasad B, Unadkat JD.

Drug Metab Dispos. 2018 Feb;46(2):189-196. doi: 10.1124/dmd.117.077289. Epub 2017 Nov 14.

13.

Concise Review: Current and Emerging Biomarkers of Nephrotoxicity.

Weber EJ, Himmelfarb J, Kelly EJ.

Curr Opin Toxicol. 2017 Jun;4:16-21. doi: 10.1016/j.cotox.2017.03.002. Epub 2017 Apr 12.

14.

CORYNEBACTERIUM PSEUDOTUBERCULOSIS AND COPPER DEFICIENCY IN A MALE ROCKY MOUNTAIN BIGHORN SHEEP ( OVIS CANADENSIS CANADENSIS) IN UTAH, USA.

Kelly EJ, Roug A, Jones C, Seamons J, Hall JO.

J Wildl Dis. 2018 Jan;54(1):193-195. doi: 10.7589/2017-05-099. Epub 2017 Oct 4.

PMID:
28977770
15.

Microphysiological Systems to Assess Nonclinical Toxicity.

Van Ness KP, Chang SY, Weber EJ, Zumpano D, Eaton DL, Kelly EJ.

Curr Protoc Toxicol. 2017 Aug 4;73:14.18.1-14.18.28. doi: 10.1002/cptx.27.

16.

Longitudinal characterisation of function and structure of Bietti crystalline dystrophy: report on a novel homozygous mutation in CYP4V2.

Lockhart CM, Smith TB, Yang P, Naidu M, Rettie AE, Nath A, Weleber R, Kelly EJ.

Br J Ophthalmol. 2018 Feb;102(2):187-194. doi: 10.1136/bjophthalmol-2016-309696. Epub 2017 Jul 11.

17.

Oncolytic VSV Primes Differential Responses to Immuno-oncology Therapy.

Durham NM, Mulgrew K, McGlinchey K, Monks NR, Ji H, Herbst R, Suzich J, Hammond SA, Kelly EJ.

Mol Ther. 2017 Aug 2;25(8):1917-1932. doi: 10.1016/j.ymthe.2017.05.006. Epub 2017 Jun 2.

18.

Characterization of rat or human hepatocytes cultured in microphysiological systems (MPS) to identify hepatotoxicity.

Chang SY, Voellinger JL, Van Ness KP, Chapron B, Shaffer RM, Neumann T, White CC, Kavanagh TJ, Kelly EJ, Eaton DL.

Toxicol In Vitro. 2017 Apr;40:170-183. doi: 10.1016/j.tiv.2017.01.007. Epub 2017 Jan 13.

PMID:
28089783
19.

Does Demand for Breast Augmentation Reflect National Financial Trends?

Kearney L, Dolan RT, Clover AJ, Kelly EJ, O'Broin E, O'Shaughnessy M, O'Sullivan ST.

Aesthetic Plast Surg. 2017 Apr;41(2):293-297. doi: 10.1007/s00266-016-0773-z. Epub 2017 Jan 7.

PMID:
28062963
20.

Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics.

Prasad B, Johnson K, Billington S, Lee C, Chung GW, Brown CD, Kelly EJ, Himmelfarb J, Unadkat JD.

Drug Metab Dispos. 2016 Dec;44(12):1920-1924. Epub 2016 Sep 12.

21.

Pseudomonas aeruginosa mastitis in two goats associated with an essential oil-based teat dip.

Kelly EJ, Wilson DJ.

J Vet Diagn Invest. 2016 Nov;28(6):760-762. Epub 2016 Oct 3.

PMID:
27698173
22.

Transporter Expression in Liver Tissue from Subjects with Alcoholic or Hepatitis C Cirrhosis Quantified by Targeted Quantitative Proteomics.

Wang L, Collins C, Kelly EJ, Chu X, Ray AS, Salphati L, Xiao G, Lee C, Lai Y, Liao M, Mathias A, Evers R, Humphreys W, Hop CE, Kumer SC, Unadkat JD.

Drug Metab Dispos. 2016 Nov;44(11):1752-1758. Epub 2016 Aug 19.

23.

Development of a microphysiological model of human kidney proximal tubule function.

Weber EJ, Chapron A, Chapron BD, Voellinger JL, Lidberg KA, Yeung CK, Wang Z, Yamaura Y, Hailey DW, Neumann T, Shen DD, Thummel KE, Muczynski KA, Himmelfarb J, Kelly EJ.

Kidney Int. 2016 Sep;90(3):627-37. doi: 10.1016/j.kint.2016.06.011.

24.

Myxofibrosarcoma in the Thenar Eminence.

Martin-Smith J, McInerney N, Buckley C, Gilmore J, Kelly EJ.

Ann Plast Surg. 2017 Jan;78(1):46-48.

PMID:
27505448
25.

Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity.

Parkinson OT, Teitelbaum AM, Whittington D, Kelly EJ, Rettie AE.

Drug Metab Dispos. 2016 Oct;44(10):1598-602. doi: 10.1124/dmd.116.070003. Epub 2016 Jul 28.

26.

Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function.

Chang SY, Weber EJ, Ness KV, Eaton DL, Kelly EJ.

Clin Pharmacol Ther. 2016 Nov;100(5):464-478. doi: 10.1002/cpt.436. Epub 2016 Aug 27. Review.

27.

Cerebrospinal Fluid Flow Studies and Recent Advancements.

Kelly EJ, Yamada S.

Semin Ultrasound CT MR. 2016 Apr;37(2):92-9. doi: 10.1053/j.sult.2016.01.002. Epub 2016 Jan 7. Review.

PMID:
27063659
28.

CYP2D6 Is Inducible by Endogenous and Exogenous Corticosteroids.

Farooq M, Kelly EJ, Unadkat JD.

Drug Metab Dispos. 2016 May;44(5):750-7. doi: 10.1124/dmd.115.069229. Epub 2016 Mar 10. Retraction in: Drug Metab Dispos. 2018 Sep;46(9):1360.

29.

An unusual penetrating hand injury from a hurling helmet.

Joyce CW, Kelly EJ.

Injury. 2015 Dec;46(12):2520-1. doi: 10.1016/j.injury.2015.10.028. Epub 2015 Oct 20.

PMID:
26525097
30.

Pharmacokinetics of metoprolol during pregnancy and lactation.

Ryu RJ, Eyal S, Easterling TR, Caritis SN, Venkataraman R, Hankins G, Rytting E, Thummel K, Kelly EJ, Risler L, Phillips B, Honaker MT, Shen DD, Hebert MF.

J Clin Pharmacol. 2016 May;56(5):581-9. doi: 10.1002/jcph.631. Epub 2015 Dec 4.

31.

Pathology in Practice. Dermatitis, cellulitis, and myositis caused by S marcescens infection in a cat.

Kelly EJ, Baldwin TJ, Chamberlain AP.

J Am Vet Med Assoc. 2015 Oct 15;247(8):897-9. doi: 10.2460/javma.247.8.897. No abstract available.

PMID:
26421401
32.

A Quantitative Approach to Screen for Nephrotoxic Compounds In Vitro.

Adler M, Ramm S, Hafner M, Muhlich JL, Gottwald EM, Weber E, Jaklic A, Ajay AK, Svoboda D, Auerbach S, Kelly EJ, Himmelfarb J, Vaidya VS.

J Am Soc Nephrol. 2016 Apr;27(4):1015-28. doi: 10.1681/ASN.2015010060. Epub 2015 Aug 10.

33.

Webinar: A useful tool in plastic surgery specialty trainee education.

Martin-Smith JD, McArdle A, Carroll SM, Kelly EJ.

J Plast Reconstr Aesthet Surg. 2015 Sep;68(9):1323-4. doi: 10.1016/j.bjps.2015.05.034. Epub 2015 May 28. No abstract available.

PMID:
26058725
34.

Dilated Cardiomyopathy in a Rio Grande Wild Turkey (Meleagris gallopavo intermedia) in Southern Utah, USA, 2013.

Frame DD, Kelly EJ, Van Wettere A.

J Wildl Dis. 2015 Jul;51(3):790-2. doi: 10.7589/2014-09-228. Epub 2015 Apr 28.

PMID:
25919467
35.

Cosmetic surgical practice: are we complying with professional standards?

Kearney L, de Blacam C, Clover AJ, Kelly EJ, O'Shaughnessy M, O'Sullivan ST, O'Broin E.

Aesthetic Plast Surg. 2015 Jun;39(3):449-51. doi: 10.1007/s00266-015-0485-9. Epub 2015 Apr 22.

PMID:
25900450
36.

Identification of CYP3A7 for glyburide metabolism in human fetal livers.

Shuster DL, Risler LJ, Prasad B, Calamia JC, Voellinger JL, Kelly EJ, Unadkat JD, Hebert MF, Shen DD, Thummel KE, Mao Q.

Biochem Pharmacol. 2014 Dec 15;92(4):690-700. doi: 10.1016/j.bcp.2014.09.025. Epub 2014 Oct 22.

37.

Identification of amino acid determinants in CYP4B1 for optimal catalytic processing of 4-ipomeanol.

Wiek C, Schmidt EM, Roellecke K, Freund M, Nakano M, Kelly EJ, Kaisers W, Yarov-Yarovoy V, Kramm CM, Rettie AE, Hanenberg H.

Biochem J. 2015 Jan 1;465(1):103-14. doi: 10.1042/BJ20140813.

38.

Gene expression in whole lung and pulmonary macrophages reflects the dynamic pathology associated with airway surface dehydration.

Saini Y, Dang H, Livraghi-Butrico A, Kelly EJ, Jones LC, O'Neal WK, Boucher RC.

BMC Genomics. 2014 Sep 10;15:726. doi: 10.1186/1471-2164-15-726.

39.

Generation and characterization of a murine model of Bietti crystalline dystrophy.

Lockhart CM, Nakano M, Rettie AE, Kelly EJ.

Invest Ophthalmol Vis Sci. 2014 Aug 12;55(9):5572-81. doi: 10.1167/iovs.13-13717.

40.

Current and emerging MR imaging techniques for the diagnosis and management of CSF flow disorders: a review of phase-contrast and time-spatial labeling inversion pulse.

Yamada S, Tsuchiya K, Bradley WG, Law M, Winkler ML, Borzage MT, Miyazaki M, Kelly EJ, McComb JG.

AJNR Am J Neuroradiol. 2015 Apr;36(4):623-30. doi: 10.3174/ajnr.A4030. Epub 2014 Jul 10. Review.

41.

Ocular cytochrome P450s and transporters: roles in disease and endobiotic and xenobiotic disposition.

Nakano M, Lockhart CM, Kelly EJ, Rettie AE.

Drug Metab Rev. 2014 Aug;46(3):247-60. doi: 10.3109/03602532.2014.921190. Epub 2014 May 26. Review.

42.

Innovations in preclinical biology: ex vivo engineering of a human kidney tissue microperfusion system.

Kelly EJ, Wang Z, Voellinger JL, Yeung CK, Shen DD, Thummel KE, Zheng Y, Ligresti G, Eaton DL, Muczynski KA, Duffield JS, Neumann T, Tourovskaia A, Fauver M, Kramer G, Asp E, Himmelfarb J.

Stem Cell Res Ther. 2013;4 Suppl 1:S17. doi: 10.1186/scrt378. Epub 2013 Dec 20. Review.

43.

Effect of gestational age on mRNA and protein expression of polyspecific organic cation transporters during pregnancy.

Lee N, Hebert MF, Prasad B, Easterling TR, Kelly EJ, Unadkat JD, Wang J.

Drug Metab Dispos. 2013 Dec;41(12):2225-32. doi: 10.1124/dmd.113.054072. Epub 2013 Oct 7.

44.

Electrochemotherapy for the treatment of ocular basal cell carcinoma; a novel adjunct in the disease management.

Salwa SP, Bourke MG, Forde PF, O'Shaughnessy M, O'Sullivan ST, Kelly EJ, Soden DM, Clover AJ.

J Plast Reconstr Aesthet Surg. 2014 Mar;67(3):403-6. doi: 10.1016/j.bjps.2013.07.019. Epub 2013 Aug 1.

PMID:
23916385
45.

Generation and characterization of a Cyp4b1 null mouse and the role of CYP4B1 in the activation and toxicity of Ipomeanol.

Parkinson OT, Liggitt HD, Rettie AE, Kelly EJ.

Toxicol Sci. 2013 Aug;134(2):243-50. doi: 10.1093/toxsci/kft123. Epub 2013 Jun 7.

46.

Loss of Cftr function exacerbates the phenotype of Na(+) hyperabsorption in murine airways.

Livraghi-Butrico A, Kelly EJ, Wilkinson KJ, Rogers TD, Gilmore RC, Harkema JR, Randell SH, Boucher RC, O'Neal WK, Grubb BR.

Am J Physiol Lung Cell Mol Physiol. 2013 Apr 1;304(7):L469-80. doi: 10.1152/ajplung.00150.2012. Epub 2013 Feb 1.

47.

In situ cell-matrix mechanics in tendon fascicles and seeded collagen gels: implications for the multiscale design of biomaterials.

Duncan NA, Bruehlmann SB, Hunter CJ, Shao X, Kelly EJ.

Comput Methods Biomech Biomed Engin. 2014;17(1):39-47. doi: 10.1080/10255842.2012.742075. Epub 2012 Dec 13.

PMID:
23237459
48.

Pathology in practice. Echinococcosis (hydatidosis) in a sheep.

Kelly EJ, Baldwin TJ, Rood KA.

J Am Vet Med Assoc. 2012 Dec 1;241(11):1449-51. doi: 10.2460/javma.241.11.1449. No abstract available.

PMID:
23176235
49.

Hepatic Cyp2d and Cyp26a1 mRNAs and activities are increased during mouse pregnancy.

Topletz AR, Le HN, Lee N, Chapman JD, Kelly EJ, Wang J, Isoherranen N.

Drug Metab Dispos. 2013 Feb;41(2):312-9. doi: 10.1124/dmd.112.049379. Epub 2012 Nov 13.

50.

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