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Items: 1 to 50 of 256

1.

Early and late responses in patients with rheumatoid arthritis who were conventional synthetic disease-modifying anti-rheumatic drug inadequate responders and were treated with tocilizumab or switched to rituximab: an open-label phase 3 trial (MIRAI).

Dörner T, Schulze-Koops H, Burmester GR, Iking-Konert C, Schmalzing M, Engel A, Kästner P, Kellner H, Kurthen R, Krüger K, Rubbert-Roth A, Schwenke H, Peters MA, Tony HP.

Clin Exp Rheumatol. 2019 Apr 16. [Epub ahead of print]

PMID:
31025930
2.

Draft Genome Sequence of the Wood-Staining Ascomycete Chlorociboria aeruginascens DSM 107184.

Büttner E, Liers C, Gebauer AM, Collemare J, Navarro-Muñoz JC, Hofrichter M, Kellner H.

Microbiol Resour Announc. 2019 Apr 25;8(17). pii: e00249-19. doi: 10.1128/MRA.00249-19.

3.

Draft Genome Sequence of Xylaria longipes DSM 107183, a Saprotrophic Ascomycete Colonizing Hardwood.

Büttner E, Gebauer AM, Hofrichter M, Liers C, Kellner H.

Microbiol Resour Announc. 2019 Mar 21;8(12). pii: e00157-19. doi: 10.1128/MRA.00157-19.

4.

Effects of BI 655064, an antagonistic anti-CD40 antibody, on clinical and biomarker variables in patients with active rheumatoid arthritis: a randomised, double-blind, placebo-controlled, phase IIa study.

Visvanathan S, Daniluk S, Ptaszyński R, Müller-Ladner U, Ramanujam M, Rosenstock B, Eleftheraki AG, Vinisko R, Petříková A, Kellner H, Dokoupilova E, Kwiatkowska B, Alten R, Schwabe C, Baum P, Joseph D, Fine JS, Padula SJ, Steffgen J.

Ann Rheum Dis. 2019 Jun;78(6):754-760. doi: 10.1136/annrheumdis-2018-214729. Epub 2019 Mar 22.

5.

Genome and secretome of Chondrostereum purpureum correspond to saprotrophic and phytopathogenic life styles.

Reina R, Kellner H, Hess J, Jehmlich N, García-Romera I, Aranda E, Hofrichter M, Liers C.

PLoS One. 2019 Mar 1;14(3):e0212769. doi: 10.1371/journal.pone.0212769. eCollection 2019.

6.

Molecular fungal community and its decomposition activity in sapwood and heartwood of 13 temperate European tree species.

Leonhardt S, Hoppe B, Stengel E, Noll L, Moll J, Bässler C, Dahl A, Buscot F, Hofrichter M, Kellner H.

PLoS One. 2019 Feb 14;14(2):e0212120. doi: 10.1371/journal.pone.0212120. eCollection 2019.

7.

The YoaW signal peptide directs efficient secretion of different heterologous proteins fused to a StrepII-SUMO tag in Bacillus subtilis.

Heinrich J, Drewniok C, Neugebauer E, Kellner H, Wiegert T.

Microb Cell Fact. 2019 Feb 7;18(1):31. doi: 10.1186/s12934-019-1078-0.

8.

Draft Genome Sequence of Scytalidium lignicola DSM 105466, a Ubiquitous Saprotrophic Fungus.

Büttner E, Gebauer AM, Hofrichter M, Liers C, Kellner H.

Microbiol Resour Announc. 2018 Oct 11;7(14). pii: e01208-18. doi: 10.1128/MRA.01208-18. eCollection 2018 Oct.

9.

Determinants of Deadwood-Inhabiting Fungal Communities in Temperate Forests: Molecular Evidence From a Large Scale Deadwood Decomposition Experiment.

Purahong W, Wubet T, Lentendu G, Hoppe B, Jariyavidyanont K, Arnstadt T, Baber K, Otto P, Kellner H, Hofrichter M, Bauhus J, Weisser WW, Krüger D, Schulze ED, Kahl T, Buscot F.

Front Microbiol. 2018 Sep 20;9:2120. doi: 10.3389/fmicb.2018.02120. eCollection 2018.

10.

Rituximab in routine care of severe active rheumatoid arthritis : A prospective, non-interventional study in Germany.

Krause A, Aries PM, Berger S, Fiehn C, Kellner H, Lorenz HM, Meier L, Müller GA, Müller-Ladner U, Schwarting A, Tony HP, Peters MA, Wendler J.

Z Rheumatol. 2018 Oct 1. doi: 10.1007/s00393-018-0552-0. [Epub ahead of print]

PMID:
30276727
11.

Bacteria inhabiting deadwood of 13 tree species are heterogeneously distributed between sapwood and heartwood.

Moll J, Kellner H, Leonhardt S, Stengel E, Dahl A, Bässler C, Buscot F, Hofrichter M, Hoppe B.

Environ Microbiol. 2018 Oct;20(10):3744-3756. doi: 10.1111/1462-2920.14376. Epub 2018 Sep 17.

PMID:
30109768
12.

[S2e guideline: treatment of rheumatoid arthritis with disease-modifying drugs].

Fiehn C, Holle J, Iking-Konert C, Leipe J, Weseloh C, Frerix M, Alten R, Behrens F, Baerwald C, Braun J, Burkhardt H, Burmester G, Detert J, Gaubitz M, Gause A, Gromnica-Ihle E, Kellner H, Krause A, Kuipers J, Lorenz HM, Müller-Ladner U, Nothacker M, Nüsslein H, Rubbert-Roth A, Schneider M, Schulze-Koops H, Seitz S, Sitter H, Specker C, Tony HP, Wassenberg S, Wollenhaupt J, Krüger K.

Z Rheumatol. 2018 Aug;77(Suppl 2):35-53. doi: 10.1007/s00393-018-0481-y. Review. German.

PMID:
29968101
13.

Effects of different management regimes on microbial biodiversity in vineyard soils.

Hendgen M, Hoppe B, Döring J, Friedel M, Kauer R, Frisch M, Dahl A, Kellner H.

Sci Rep. 2018 Jun 20;8(1):9393. doi: 10.1038/s41598-018-27743-0.

14.

Increasing N deposition impacts neither diversity nor functions of deadwood-inhabiting fungal communities, but adaptation and functional redundancy ensure ecosystem function.

Purahong W, Wubet T, Kahl T, Arnstadt T, Hoppe B, Lentendu G, Baber K, Rose T, Kellner H, Hofrichter M, Bauhus J, Krüger D, Buscot F.

Environ Microbiol. 2018 May;20(5):1693-1710. doi: 10.1111/1462-2920.14081. Epub 2018 Apr 6.

PMID:
29473288
15.

Draft Genome Sequence of the Sordariomycete Lecythophora (Coniochaeta) hoffmannii CBS 245.38.

Leonhardt S, Büttner E, Gebauer AM, Hofrichter M, Kellner H.

Genome Announc. 2018 Feb 15;6(7). pii: e01510-17. doi: 10.1128/genomeA.01510-17.

16.

The genome sequence of the commercially cultivated mushroom Agrocybe aegerita reveals a conserved repertoire of fruiting-related genes and a versatile suite of biopolymer-degrading enzymes.

Gupta DK, Rühl M, Mishra B, Kleofas V, Hofrichter M, Herzog R, Pecyna MJ, Sharma R, Kellner H, Hennicke F, Thines M.

BMC Genomics. 2018 Jan 15;19(1):48. doi: 10.1186/s12864-017-4430-y.

17.

Draft Genome Sequence of the Wood-Degrading Ascomycete Kretzschmaria deusta DSM 104547.

Büttner E, Gebauer AM, Hofrichter M, Liers C, Kellner H.

Genome Announc. 2017 Oct 26;5(43). pii: e01076-17. doi: 10.1128/genomeA.01076-17.

18.

Discovering Protein-Coding Genes from the Environment: Time for the Eukaryotes?

Marmeisse R, Kellner H, Fraissinet-Tachet L, Luis P.

Trends Biotechnol. 2017 Sep;35(9):824-835. doi: 10.1016/j.tibtech.2017.02.003. Epub 2017 Mar 7. Review.

PMID:
28279485
19.

Repeatability and response to therapy of dynamic contrast-enhanced magnetic resonance imaging biomarkers in rheumatoid arthritis in a large multicentre trial setting.

Waterton JC, Ho M, Nordenmark LH, Jenkins M, DiCarlo J, Guillard G, Roberts C, Buonaccorsi G, Parker GJM, Bowes MA, Peterfy C, Kellner H, Taylor PC.

Eur Radiol. 2017 Sep;27(9):3662-3668. doi: 10.1007/s00330-017-4736-9. Epub 2017 Jan 23.

20.

A Peroxygenase from Chaetomium globosum Catalyzes the Selective Oxygenation of Testosterone.

Kiebist J, Schmidtke KU, Zimmermann J, Kellner H, Jehmlich N, Ullrich R, Zänder D, Hofrichter M, Scheibner K.

Chembiochem. 2017 Mar 16;18(6):563-569. doi: 10.1002/cbic.201600677. Epub 2017 Mar 1.

21.

Draft Genome Sequence of the Chloroperoxidase-Producing Fungus Caldariomyces fumago Woronichin DSM1256.

Kellner H, Pecyna MJ, Buchhaupt M, Ullrich R, Hofrichter M.

Genome Announc. 2016 Aug 4;4(4). pii: e00774-16. doi: 10.1128/genomeA.00774-16.

22.

Long-term effects of secukinumab on MRI findings in relation to clinical efficacy in subjects with active ankylosing spondylitis: an observational study.

Baraliakos X, Borah B, Braun J, Baeten D, Laurent D, Sieper J, Emery P, McInnes IB, van Laar JM, Wordsworth P, Wollenhaupt J, Kellner H, Colin L, Vandenhende F, Radford K, Hueber W.

Ann Rheum Dis. 2016 Feb;75(2):408-12. doi: 10.1136/annrheumdis-2015-207544. Epub 2015 Aug 6.

PMID:
26248638
23.

Fungal unspecific peroxygenases: heme-thiolate proteins that combine peroxidase and cytochrome p450 properties.

Hofrichter M, Kellner H, Pecyna MJ, Ullrich R.

Adv Exp Med Biol. 2015;851:341-68. doi: 10.1007/978-3-319-16009-2_13. Review.

PMID:
26002742
24.

[German Society for Rheumatology S3 guidelines on axial spondyloarthritis including Bechterew's disease and early forms: 8.4 Pharmaceutical therapy, 8.5 Evaluation of therapy success of pharmaceutical measures].

Kiltz U, Sieper J, Kellner H, Krause D, Rudwaleit M, Chenot JF, Stallmach A, Jaresch S, Braun J; German Society for Rheumatology.

Z Rheumatol. 2014 Sep;73 Suppl 2:78-96. doi: 10.1007/s00393-014-1443-7. German. No abstract available.

PMID:
25181978
25.

[German Society for Rheumatology S3 guidelines on axial spondyloarthritis including Bechterew's disease and early forms: 8 Therapy, 8.1 Treatment concept, 8.2 Therapy targets and strategy].

Kiltz U, Sieper J, Rudwaleit M, Kellner H, Krause D, Böhle E, Böhm H, Böhncke WH, Chenot JF, Heiligenhaus A, Jaresch S, Mau W, Oberschelp U, Pleyer U, Repschläger U, Schneider E, Smolenski U, Stallmach A, Stemmer M, Swoboda B, Ulrich C, Winking M, Braun J; German Society for Rheumatology.

Z Rheumatol. 2014 Sep;73 Suppl 2:69-70. doi: 10.1007/s00393-014-1433-9. German. No abstract available.

PMID:
25181976
26.

[German Society for Rheumatology S3 guidelines on axial spondyloarthritis including Bechterew's disease and early forms: 2 Preamble].

Kiltz U, Sieper J, Rudwaleit M, Kellner H, Krause D, Böhle E, Böhm H, Böhncke WH, Chenot JF, Heiligenhaus A, Hermann KG, Jaresch S, Mau W, Oberschelp U, Pleyer U, Repschläger U, Schneider E, Smolenski U, Stallmach A, Stemmer M, Swoboda B, Ulrich C, Winking M, Braun J; German Society for Rheumatology.

Z Rheumatol. 2014 Sep;73 Suppl 2:26-7. doi: 10.1007/s00393-014-1427-7. German. No abstract available.

PMID:
25181970
27.

[German Society for Rheumatology S3 guidelines on axial spondyloarthritis including Bechterew's disease and early forms: 1 Introduction/preliminary comments].

Kiltz U, Sieper J, Rudwaleit M, Kellner H, Krause D, Böhle E, Böhm H, Böhncke WH, Chenot JF, Heiligenhaus A, Hermann KG, Jaresch S, Mau W, Oberschelp U, Pleyer U, Repschläger U, Schneider E, Smolenski U, Stallmach A, Stemmer M, Swoboda B, Ulrich C, Winking M, Braun J; German Society for Rheumatology.

Z Rheumatol. 2014 Sep;73 Suppl 2:23-5. doi: 10.1007/s00393-014-1426-8. German. No abstract available.

PMID:
25181969
28.

[32-year-old man with joint pain and swelling].

Kellner H.

Dtsch Med Wochenschr. 2014 Sep;139(37):1821-2. doi: 10.1055/s-0034-1387234. Epub 2014 Sep 2. German. No abstract available.

PMID:
25180997
29.

Differences in the secretion pattern of oxidoreductases from Bjerkandera adusta induced by a phenolic olive mill extract.

Reina R, Kellner H, Jehmlich N, Ullrich R, García-Romera I, Aranda E, Liers C.

Fungal Genet Biol. 2014 Nov;72:99-105. doi: 10.1016/j.fgb.2014.07.009. Epub 2014 Jul 25.

PMID:
25069088
30.

Infliximab efficacy in rheumatoid arthritis after an inadequate response to etanercept or adalimumab: results of a target-driven active switch study.

Fleischmann R, Goldman JA, Leirisalo-Repo M, Zanetakis E, El-Kadi H, Kellner H, Bolce R, DeHoratius R, Wang J, Decktor D.

Curr Med Res Opin. 2014 Nov;30(11):2139-49. doi: 10.1185/03007995.2014.942416. Epub 2014 Jul 30.

PMID:
25050591
31.

["Tender finger joints"].

Kellner H.

MMW Fortschr Med. 2014 Jun 12;156(11):41-3. Review. German. No abstract available.

PMID:
25022099
32.

Widespread occurrence of expressed fungal secretory peroxidases in forest soils.

Kellner H, Luis P, Pecyna MJ, Barbi F, Kapturska D, Krüger D, Zak DR, Marmeisse R, Vandenbol M, Hofrichter M.

PLoS One. 2014 Apr 24;9(4):e95557. doi: 10.1371/journal.pone.0095557. eCollection 2014.

33.

Degradation of atrazine by Frankia alni ACN14a: gene regulation, dealkylation, and dechlorination.

Rehan M, Kluge M, Fränzle S, Kellner H, Ullrich R, Hofrichter M.

Appl Microbiol Biotechnol. 2014 Jul;98(13):6125-35. doi: 10.1007/s00253-014-5665-z. Epub 2014 Mar 28.

PMID:
24676750
34.

One-year efficacy and safety results of secukinumab in patients with rheumatoid arthritis: phase II, dose-finding, double-blind, randomized, placebo-controlled study.

Genovese MC, Durez P, Richards HB, Supronik J, Dokoupilova E, Aelion JA, Lee SH, Codding CE, Kellner H, Ikawa T, Hugot S, Ligozio G, Mpofu S.

J Rheumatol. 2014 Mar;41(3):414-21. doi: 10.3899/jrheum.130637. Epub 2014 Jan 15.

PMID:
24429175
35.

Celecoxib and Diclofenac Plus Omeprazole are Similarly Effective in the Treatment of Arthritis in Patients at High GI Risk in the CONDOR Trial.

Kellner HL, Li C, Essex MN.

Open Rheumatol J. 2013 Nov 13;7:96-100. doi: 10.2174/1874312901307010096. eCollection 2013.

36.

Evaluation of the novel ultrasound score for large joints in psoriatic arthritis and ankylosing spondylitis: six month experience in daily clinical practice.

Schäfer VS, Fleck M, Kellner H, Strunk J, Sattler H, Schmidt WA, Ehrenstein B, Backhaus M, Hartung W.

BMC Musculoskelet Disord. 2013 Dec 19;14:358. doi: 10.1186/1471-2474-14-358.

37.

[How to approach a patient with non traumatic acute painful knee swelling].

Kellner H.

MMW Fortschr Med. 2013 Oct 10;155(17):37-8. Review. German. No abstract available.

PMID:
24340385
38.

Anti-interleukin-17A monoclonal antibody secukinumab in treatment of ankylosing spondylitis: a randomised, double-blind, placebo-controlled trial.

Baeten D, Baraliakos X, Braun J, Sieper J, Emery P, van der Heijde D, McInnes I, van Laar JM, Landewé R, Wordsworth P, Wollenhaupt J, Kellner H, Paramarta J, Wei J, Brachat A, Bek S, Laurent D, Li Y, Wang YA, Bertolino AP, Gsteiger S, Wright AM, Hueber W.

Lancet. 2013 Nov 23;382(9906):1705-13. doi: 10.1016/S0140-6736(13)61134-4. Epub 2013 Sep 13. Erratum in: Lancet. 2014 May 3;383(9928):1548.

PMID:
24035250
39.

The secretome of Trametes versicolor grown on tomato juice medium and purification of the secreted oxidoreductases including a versatile peroxidase.

Carabajal M, Kellner H, Levin L, Jehmlich N, Hofrichter M, Ullrich R.

J Biotechnol. 2013 Oct 10;168(1):15-23. doi: 10.1016/j.jbiotec.2013.08.007. Epub 2013 Aug 12.

PMID:
23948257
40.

German guidelines for the sequential medical treatment of rheumatoid arthritis with traditional and biologic disease-modifying antirheumatic drugs.

Albrecht K, Krüger K, Wollenhaupt J, Alten R, Backhaus M, Baerwald C, Bolten W, Braun J, Burkhardt H, Burmester GR, Gaubitz M, Gause A, Gromnica-Ihle E, Kellner H, Kuipers J, Krause A, Lorenz HM, Manger B, Nüßlein H, Pott HG, Rubbert-Roth A, Schneider M, Specker C, Schulze-Koops H, Tony HP, Wassenberg S, Müller-Ladner U; German Society of Rheumatology.

Rheumatol Int. 2014 Jan;34(1):1-9. doi: 10.1007/s00296-013-2848-3. Epub 2013 Aug 14. Review.

PMID:
23942828
41.

Targeting interleukin-17 in patients with active rheumatoid arthritis: rationale and clinical potential.

Kellner H.

Ther Adv Musculoskelet Dis. 2013 Jun;5(3):141-52. doi: 10.1177/1759720X13485328.

42.

Assessment of therapeutic response in ankylosing spondylitis patients undergoing anti-tumour necrosis factor therapy by whole-body magnetic resonance imaging.

Karpitschka M, Godau-Kellner P, Kellner H, Horng A, Theisen D, Glaser C, Brandlhuber B, Reiser M, Weckbach S.

Eur Radiol. 2013 Jul;23(7):1773-84. doi: 10.1007/s00330-013-2794-1. Epub 2013 Mar 15.

PMID:
23494493
43.

Substrate oxidation by dye-decolorizing peroxidases (DyPs) from wood- and litter-degrading agaricomycetes compared to other fungal and plant heme-peroxidases.

Liers C, Pecyna MJ, Kellner H, Worrich A, Zorn H, Steffen KT, Hofrichter M, Ullrich R.

Appl Microbiol Biotechnol. 2013 Jul;97(13):5839-49. doi: 10.1007/s00253-012-4521-2. Epub 2012 Oct 31.

PMID:
23111597
44.

The US7 score is sensitive to change in a large cohort of patients with rheumatoid arthritis over 12 months of therapy.

Backhaus TM, Ohrndorf S, Kellner H, Strunk J, Hartung W, Sattler H, Iking-Konert C, Burmester GR, Schmidt WA, Backhaus M.

Ann Rheum Dis. 2013 Jul;72(7):1163-9. doi: 10.1136/annrheumdis-2012-201397. Epub 2012 Sep 6.

45.

[German 2012 guidelines for the sequential medical treatment of rheumatoid arthritis. Adapted EULAR recommendations and updated treatment algorithm].

Krüger K, Wollenhaupt J, Albrecht K, Alten R, Backhaus M, Baerwald C, Bolten W, Braun J, Burkhardt H, Burmester G, Gaubitz M, Gause A, Gromnica-Ihle E, Kellner H, Kuipers J, Krause A, Lorenz HM, Manger B, Nüßlein H, Pott HG, Rubbert-Roth A, Schneider M, Specker C, Schulze-Koops H, Tony HP, Wassenberg S, Müller-Ladner U; European League of Associations for Rheumatology (EULAR).

Z Rheumatol. 2012 Sep;71(7):592-603. doi: 10.1007/s00393-012-1038-0. German.

PMID:
22930110
46.

Efficacy and safety of celecoxib versus diclofenac and omeprazole in elderly arthritis patients: a subgroup analysis of the CONDOR trial.

Kellner HL, Li C, Essex MN.

Curr Med Res Opin. 2012 Sep;28(9):1537-45. Epub 2012 Aug 16.

PMID:
22852870
47.

[Magnetic resonance angiography in rheumatology].

Bley TA, Ostendorf B, Scherer A, Kellner H, Schmidt WA.

Z Rheumatol. 2012 Jul;71(5):430-5. doi: 10.1007/s00393-012-0975-y. German.

PMID:
22772889
48.

Efficacy and safety of secukinumab in patients with rheumatoid arthritis: a phase II, dose-finding, double-blind, randomised, placebo controlled study.

Genovese MC, Durez P, Richards HB, Supronik J, Dokoupilova E, Mazurov V, Aelion JA, Lee SH, Codding CE, Kellner H, Ikawa T, Hugot S, Mpofu S.

Ann Rheum Dis. 2013 Jun;72(6):863-9. doi: 10.1136/annrheumdis-2012-201601. Epub 2012 Jun 23.

PMID:
22730366
49.

The wood rot ascomycete Xylaria polymorpha produces a novel GH78 glycoside hydrolase that exhibits α-L-rhamnosidase and feruloyl esterase activities and releases hydroxycinnamic acids from lignocelluloses.

Nghi do H, Bittner B, Kellner H, Jehmlich N, Ullrich R, Pecyna MJ, Nousiainen P, Sipilä J, Huong le M, Hofrichter M, Liers C.

Appl Environ Microbiol. 2012 Jul;78(14):4893-901. doi: 10.1128/AEM.07588-11. Epub 2012 Apr 27.

50.

Reliability of the novel 7-joint ultrasound score: results from an inter- and intraobserver study performed by rheumatologists.

Ohrndorf S, Fischer IU, Kellner H, Strunk J, Hartung W, Reiche B, Burmester GR, Walther M, Schmidt WA, Backhaus M.

Arthritis Care Res (Hoboken). 2012 Aug;64(8):1238-43. doi: 10.1002/acr.21679.

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