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Items: 1 to 50 of 1058

1.

Assessment of Treatment With Sorafenib Plus Doxorubicin vs Sorafenib Alone in Patients With Advanced Hepatocellular Carcinoma: Phase 3 CALGB 80802 Randomized Clinical Trial.

Abou-Alfa GK, Shi Q, Knox JJ, Kaubisch A, Niedzwiecki D, Posey J, Tan BR Jr, Kavan P, Goel R, Lammers PE, Bekaii-Saab TS, Tam VC, Rajdev L, Kelley RK, El Dika I, Zemla T, Potaracke RI, Balletti J, El-Khoueiry AB, Harding JH, Suga JM, Schwartz LH, Goldberg RM, Bertagnolli MM, Meyerhardt J, O'Reilly EM, Venook AP.

JAMA Oncol. 2019 Sep 5. doi: 10.1001/jamaoncol.2019.2792. [Epub ahead of print]

PMID:
31486832
2.

A single H/ACA small nucleolar RNA mediates tumor suppression downstream of oncogenic RAS.

McMahon M, Contreras A, Holm M, Uechi T, Forester CM, Pang X, Jackson C, Calvert ME, Chen B, Quigley DA, Luk JM, Kelley RK, Gordan JD, Gill RM, Blanchard SC, Ruggero D.

Elife. 2019 Sep 3;8. pii: e48847. doi: 10.7554/eLife.48847. [Epub ahead of print]

3.

Second-line chemotherapy in advanced biliary cancers: A retrospective, multicenter analysis of outcomes.

Lowery MA, Goff LW, Keenan BP, Jordan E, Wang R, Bocobo AG, Chou JF, O'Reilly EM, Harding JJ, Kemeny N, Capanu M, Griffin AC, McGuire J, Venook AP, Abou-Alfa GK, Kelley RK.

Cancer. 2019 Aug 27. doi: 10.1002/cncr.32463. [Epub ahead of print]

PMID:
31454426
4.

Frequency and prognostic significance of isocitrate dehydrogenase 1 mutations in cholangiocarcinoma: a systematic literature review.

Boscoe AN, Rolland C, Kelley RK.

J Gastrointest Oncol. 2019 Aug;10(4):751-765. doi: 10.21037/jgo.2019.03.10.

5.

Molecular Profiling of Hepatocellular Carcinoma Using Circulating Cell-Free DNA.

Kaseb AO, Sánchez NS, Sen S, Kelley RK, Tan B, Bocobo AG, Lim KH, Abdel-Wahab R, Uemura M, Pestana RC, Qiao W, Xiao L, Morris J, Amin HM, Hassan MM, Rashid A, Banks KC, Lanman RB, Talasaz A, Mills-Shaw KR, George B, Haque A, Raghav KPS, Wolff RA, Yao JC, Meric-Bernstam F, Ikeda S, Kurzrock R.

Clin Cancer Res. 2019 Jul 30. doi: 10.1158/1078-0432.CCR-18-3341. [Epub ahead of print]

PMID:
31363003
6.

Prospective Phase II trial of drug-eluting bead chemoembolization for liver transplant candidates with hepatocellular carcinoma and marginal hepatic reserve.

Fidelman N, Johanson C, Kohi MP, Kolli KP, Kohlbrenner RM, Lehrman ED, Taylor AG, Kelley RK, Yao FY, Roberts JP, Kerlan RK.

J Hepatocell Carcinoma. 2019 Jun 17;6:93-103. doi: 10.2147/JHC.S206979. eCollection 2019.

7.

An unusual case of urinothorax after percutaneous nephrostolithotomy.

Dregoesc D, Kelley R, Lick D.

J Family Med Prim Care. 2019 Jun;8(6):2155-2157. doi: 10.4103/jfmpc.jfmpc_28_17.

8.

A Phase 2 Study of Galunisertib (TGF-β1 Receptor Type I Inhibitor) and Sorafenib in Patients With Advanced Hepatocellular Carcinoma.

Kelley RK, Gane E, Assenat E, Siebler J, Galle PR, Merle P, Hourmand IO, Cleverly A, Zhao Y, Gueorguieva I, Lahn M, Faivre S, Benhadji KA, Giannelli G.

Clin Transl Gastroenterol. 2019 Jul;10(7):e00056. doi: 10.14309/ctg.0000000000000056.

PMID:
31295152
9.

Identification and characterization of an octameric PEG-protein conjugate system for intravitreal long-acting delivery to the back of the eye.

Shatz W, Hass PE, Peer N, Paluch MT, Blanchette C, Han G, Sandoval W, Morando A, Loyet KM, Bantseev V, Booler H, Crowell S, Kamath A, Scheer JM, Kelley RF.

PLoS One. 2019 Jun 28;14(6):e0218613. doi: 10.1371/journal.pone.0218613. eCollection 2019.

10.

Protein conjugates and fusion proteins as ocular therapeutics.

Mehta SC, Kelley RF, Tesar DB.

Drug Discov Today. 2019 Aug;24(8):1440-1445. doi: 10.1016/j.drudis.2019.05.025. Epub 2019 Jun 13.

PMID:
31202674
11.

Energy calibration of high-resolution X-Ray TES microcalorimeters with 3 eV optical photons.

Jaeckel FT, Ambarish CV, Christensen N, Gruenke R, Hu L, McCammon D, McPheron M, Meyer M, Nelms KL, Roy A, Wulf D, Zhang S, Zhou Y, Adams JS, Bandler SR, Chervenak JA, Datesman AM, Eckart ME, Ewin AJ, Finkbeiner FM, Kelley R, Kilbourne CA, Miniussi AR, Porter FS, Sadleir JE, Sakai K, Smith SJ, Wakeham N, Wassell E, Yoon W, Morgan KM, Schmidt DR, Swetz DS, Ullom JN.

IEEE Trans Appl Supercond. 2019 Aug;29(5). pii: 2100104. doi: 10.1109/TASC.2019.2899856. Epub 2019 Feb 18.

12.

Mapping TES Temperature Sensitivity and Current Sensitivity as a Function of Temperature, Current, and Magnetic Field with IV curve and Complex Admittance Measurements.

Zhou Y, Ambarish CV, Gruenke R, Jaeckel FT, Kripps KL, McCammon D, Morgan KM, Wulf D, Zhang S, Adams JS, Bandler SR, Chervenak JA, Datesman AM, Eckart ME, Ewin AJ, Finkbeiner FM, Kelley RL, Kilbourne CA, Miniussi AR, Porter FS, Sadleir JE, Sakai K, Smith SJ, Wakeham NA, Wassell EJ, Yoon W.

J Low Temp Phys. 2018 Nov;193(3-4):321-327. doi: 10.1007/s10909-018-1970-8. Epub 2018 May 29.

13.

Demonstration of Athena X-IFU Compatible 40-Row Time-Division-Multiplexed Readout.

Durkin M, Adams JS, Bandler SR, Chervenak JA, Chaudhuri S, Dawson CS, Denison EV, Doriese WB, Duff SM, Finkbeiner FM, FitzGerald CT, Fowler JW, Gard JD, Hilton GC, Irwin KD, Joe YI, Kelley RL, Kilbourne CA, Miniussi AR, Morgan KM, O'Neil GC, Pappas CG, Porter FS, Reintsema CD, Rudman DA, SaKai K, Smith SJ, Stevens RW, Swetz DS, Szypryt P, Ullom JN, Vale LR, Wakeham N, Weber JC, Young BA.

IEEE Trans Appl Supercond. 2019 Aug;29(5). pii: 2101005. doi: 10.1109/TASC.2019.2904472. Epub 2019 Mar 19.

PMID:
31160861
14.

Nivolumab in patients with advanced hepatocellular carcinoma and Child-Pugh class B cirrhosis: Safety and clinical outcomes in a retrospective case series.

Kambhampati S, Bauer KE, Bracci PM, Keenan BP, Behr SC, Gordan JD, Kelley RK.

Cancer. 2019 Sep 15;125(18):3234-3241. doi: 10.1002/cncr.32206. Epub 2019 Jun 2.

PMID:
31154669
15.

Individual culture and atmospheric oxygen during culture affect mouse preimplantation embryo metabolism and post-implantation development.

Kelley RL, Gardner DK.

Reprod Biomed Online. 2019 Jul;39(1):3-18. doi: 10.1016/j.rbmo.2019.03.102. Epub 2019 Mar 11.

PMID:
31122833
16.

TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion-Positive Intrahepatic Cholangiocarcinoma.

Goyal L, Shi L, Liu LY, Fece de la Cruz F, Lennerz JK, Raghavan S, Leschiner I, Elagina L, Siravegna G, Ng RWS, Vu P, Patra KC, Saha SK, Uppot RN, Arellano R, Reyes S, Sagara T, Otsuki S, Nadres B, Shahzade HA, Dey-Guha I, Fetter IJ, Baiev I, Van Seventer EE, Murphy JE, Ferrone CR, Tanabe KK, Deshpande V, Harding JJ, Yaeger R, Kelley RK, Bardelli A, Iafrate AJ, Hahn WC, Benes CH, Ting DT, Hirai H, Getz G, Juric D, Zhu AX, Corcoran RB, Bardeesy N.

Cancer Discov. 2019 Aug;9(8):1064-1079. doi: 10.1158/2159-8290.CD-19-0182. Epub 2019 May 20.

PMID:
31109923
17.

The Implementation of Dementia Care Mapping in a Randomized Controlled Trial in Long-Term Care: Results of a Process Evaluation.

Surr CA, Griffiths AW, Kelley R, Holloway I, Walwyn REA, Martin A, McDermid J, Chenoweth L, Farrin AJ.

Am J Alzheimers Dis Other Demen. 2019 Sep;34(6):390-398. doi: 10.1177/1533317519845725. Epub 2019 May 5.

18.

The impacts of family involvement on general hospital care experiences for people living with dementia: An ethnographic study.

Kelley R, Godfrey M, Young J.

Int J Nurs Stud. 2019 Aug;96:72-81. doi: 10.1016/j.ijnurstu.2019.04.004. Epub 2019 Apr 13.

PMID:
31053337
19.

Emerging Role for Systemic Therapy in Earlier Stages of HCC.

Kelley RK.

Int J Radiat Oncol Biol Phys. 2018 Dec 1;102(5):1407. doi: 10.1016/j.ijrobp.2018.08.062. No abstract available.

PMID:
31014785
20.

Novel transforming growth factor beta receptor I kinase inhibitor galunisertib (LY2157299) in advanced hepatocellular carcinoma.

Faivre S, Santoro A, Kelley RK, Gane E, Costentin CE, Gueorguieva I, Smith C, Cleverly A, Lahn MM, Raymond E, Benhadji KA, Giannelli G.

Liver Int. 2019 Aug;39(8):1468-1477. doi: 10.1111/liv.14113. Epub 2019 Jun 3.

PMID:
30963691
21.

Guidelines Insights: Hepatobiliary Cancers, Version 2.2019.

Benson AB, D'Angelica MI, Abbott DE, Abrams TA, Alberts SR, Anaya DA, Anders R, Are C, Brown D, Chang DT, Cloyd J, Covey AM, Hawkins W, Iyer R, Jacob R, Karachristos A, Kelley RK, Kim R, Palta M, Park JO, Sahai V, Schefter T, Sicklick JK, Singh G, Sohal D, Stein S, Tian GG, Vauthey JN, Venook AP, Hammond LJ, Darlow SD.

J Natl Compr Canc Netw. 2019 Apr 1;17(4):302-310. doi: 10.6004/jnccn.2019.0019.

PMID:
30959462
22.

A Tale of Two Valleys: Disparity in Sin Nombre Virus Antibody Reactivity Between Neighboring Mojave Desert Communities.

Pesapane R, Enge B, Roy A, Kelley R, Mabry K, Trainor BC, Clifford D, Foley J.

Vector Borne Zoonotic Dis. 2019 Apr;19(4):290-294. doi: 10.1089/vbz.2018.2341. Epub 2018 Dec 1.

PMID:
30932773
23.

Effect of deep brain stimulation on vocal motor control mechanisms in Parkinson's disease.

Behroozmand R, Johari K, Kelley RM, Kapnoula EC, Narayanan NS, Greenlee JDW.

Parkinsonism Relat Disord. 2019 Jun;63:46-53. doi: 10.1016/j.parkreldis.2019.03.002. Epub 2019 Mar 7.

PMID:
30871801
24.

Barriers and facilitators to implementing dementia care mapping in care homes: results from the DCM™ EPIC trial process evaluation.

Griffiths AW, Kelley R, Garrod L, Perfect D, Robinson O, Shoesmith E, McDermid J, Burnley N, Surr CA.

BMC Geriatr. 2019 Feb 8;19(1):37. doi: 10.1186/s12877-019-1045-y.

25.

Genomic profiling of combined hepatocellular-cholangiocarcinoma reveals similar genetics to hepatocellular carcinoma.

Joseph NM, Tsokos CG, Umetsu SE, Shain AH, Kelley RK, Onodera C, Bowman S, Talevich E, Ferrell LD, Kakar S, Krings G.

J Pathol. 2019 Jun;248(2):164-178. doi: 10.1002/path.5243. Epub 2019 Mar 8.

PMID:
30690729
26.

Heterogeneous Uptake of 18F-FDG and 68Ga-PSMA-11 in Hepatocellular Carcinoma.

Perez PM, Flavell RR, Kelley RK, Umetsu S, Behr SC.

Clin Nucl Med. 2019 Mar;44(3):e133-e135. doi: 10.1097/RLU.0000000000002452.

PMID:
30624275
27.

An Open-Label, Multicenter, Phase I, Dose Escalation Study with Phase II Expansion Cohort to Determine the Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Intravenous TKM-080301 in Subjects with Advanced Hepatocellular Carcinoma.

El Dika I, Lim HY, Yong WP, Lin CC, Yoon JH, Modiano M, Freilich B, Choi HJ, Chao TY, Kelley RK, Brown J, Knox J, Ryoo BY, Yau T, Abou-Alfa GK.

Oncologist. 2019 Jun;24(6):747-e218. doi: 10.1634/theoncologist.2018-0838. Epub 2018 Dec 31.

28.

The Effect of Octanoic Acid on Essential Voice Tremor: A Double-Blind, Placebo-Controlled Study.

Lowell SY, Kelley RT, Monahan M, Hosbach-Cannon CJ, Colton RH, Mihaila D.

Laryngoscope. 2019 Aug;129(8):1882-1890. doi: 10.1002/lary.27695. Epub 2018 Dec 25.

PMID:
30585335
29.

Increased dietary intake of tyrosine upregulates melanin deposition in the hair of adult black-coated dogs.

Watson A, Wayman J, Kelley R, Feugier A, Biourge V.

Anim Nutr. 2018 Dec;4(4):422-428. doi: 10.1016/j.aninu.2018.02.001. Epub 2018 Feb 16.

30.

Brain Distribution and Metabolism of Flupirtine, a Nonopioid Analgesic Drug with Antiseizure Effects, in Neonatal Rats.

Patil MA, Matter BA, Raol YH, Bourne DWA, Kelley RA, Kompella UB.

Pharmaceutics. 2018 Dec 16;10(4). pii: E281. doi: 10.3390/pharmaceutics10040281.

31.

Trehalose Limits Fragment Antibody Aggregation and Influences Charge Variant Formation in Spray-Dried Formulations at Elevated Temperatures.

Rajagopal K, Chang D, Nayak P, Izadi S, Patapoff T, Zhang J, Kelley R, Sreedhara A.

Mol Pharm. 2019 Jan 7;16(1):349-358. doi: 10.1021/acs.molpharmaceut.8b01002. Epub 2018 Dec 17.

PMID:
30525659
32.

Strategies for modifying drug residence time and ocular bioavailability to decrease treatment frequency for back of the eye diseases.

Shatz W, Aaronson J, Yohe S, Kelley RF, Kalia YN.

Expert Opin Drug Deliv. 2019 Jan;16(1):43-57. doi: 10.1080/17425247.2019.1553953. Epub 2018 Dec 7.

PMID:
30488721
33.

In Vivo Stability Profiles of Anti-factor D Molecules Support Long-Acting Delivery Approaches.

Loyet KM, Hass PE, Sandoval WN, Morando A, Liu P, Shatz W, Dickmann L, Kenrick M, Good J, Davancaze T, Morimoto AM, Kelley RF, Scheer JM.

Mol Pharm. 2019 Jan 7;16(1):86-95. doi: 10.1021/acs.molpharmaceut.8b00871. Epub 2018 Dec 3.

PMID:
30444371
34.

Cabozantinib in Hepatocellular Carcinoma.

Abou-Alfa GK, Borgman-Hagey AE, Kelley RK.

N Engl J Med. 2018 Oct 4;379(14):1384-1385. doi: 10.1056/NEJMc1810178. No abstract available.

PMID:
30281991
35.

Maternal omega-3 polyunsaturated fatty acid supplementation on offspring hip joint conformation.

Oberbauer AM, Daniels R, Levy K, Famula TR, Mundell P, Kelley R.

PLoS One. 2018 Aug 9;13(8):e0202157. doi: 10.1371/journal.pone.0202157. eCollection 2018.

36.

Vitamin D Levels in Patients with Colorectal Cancer Before and After Treatment Initiation.

Savoie MB, Paciorek A, Zhang L, Van Blarigan EL, Sommovilla N, Abrams D, Atreya CE, Bergsland EK, Chern H, Kelley RK, Ko A, Laffan A, Sarin A, Varma MG, Venook AP, Van Loon K.

J Gastrointest Cancer. 2018 Jul 30. doi: 10.1007/s12029-018-0147-7. [Epub ahead of print]

PMID:
30058032
37.

Cabozantinib in Patients with Advanced and Progressing Hepatocellular Carcinoma.

Abou-Alfa GK, Meyer T, Cheng AL, El-Khoueiry AB, Rimassa L, Ryoo BY, Cicin I, Merle P, Chen Y, Park JW, Blanc JF, Bolondi L, Klümpen HJ, Chan SL, Zagonel V, Pressiani T, Ryu MH, Venook AP, Hessel C, Borgman-Hagey AE, Schwab G, Kelley RK.

N Engl J Med. 2018 Jul 5;379(1):54-63. doi: 10.1056/NEJMoa1717002.

38.

Macrolide therapy is associated with lower mortality in community-acquired bacteraemic pneumonia.

Arnold FW, Lopardo G, Wiemken TL, Kelley R, Peyrani P, Mattingly WA, Feldman C, Gnoni M, Maurici R, Ramirez JA; Community-Acquired Pneumonia Organization (CAPO).

Respir Med. 2018 Jul;140:115-121. doi: 10.1016/j.rmed.2018.05.020. Epub 2018 Jun 5.

PMID:
29957272
39.

Neurofunctional Correlates of Response to Quetiapine in Adolescents with Bipolar Depression.

Chang K, DelBello M, Garrett A, Kelley R, Howe M, Adler C, Welge J, Strakowski SM, Singh M.

J Child Adolesc Psychopharmacol. 2018 Jul/Aug;28(6):379-386. doi: 10.1089/cap.2017.0030. Epub 2018 May 30.

40.

Retbindin Is Capable of Protecting Photoreceptors from Flavin-Sensitized Light-Mediated Cell Death In Vitro.

Kelley RA, Al-Ubaidi MR, Naash MI.

Adv Exp Med Biol. 2018;1074:485-490. doi: 10.1007/978-3-319-75402-4_60.

PMID:
29721980
41.

In Search of Mobile Applications for Urogynecology Providers.

Wallace SL, Mehta S, Farag S, Kelley RS, Chen KT.

Female Pelvic Med Reconstr Surg. 2018 Apr 11. doi: 10.1097/SPV.0000000000000580. [Epub ahead of print]

PMID:
29649079
42.

Hybrid Capture-Based Tumor Sequencing and Copy Number Analysis to Confirm Origin of Metachronous Metastases in BRCA1-Mutant Cholangiocarcinoma Harboring a Novel YWHAZ-BRAF Fusion.

Lim HC, Montesion M, Botton T, Collisson EA, Umetsu SE, Behr SC, Gordan JD, Stephens PJ, Kelley RK.

Oncologist. 2018 Sep;23(9):998-1003. doi: 10.1634/theoncologist.2017-0645. Epub 2018 Apr 5.

43.

Correction to: Power of Peer Support to Change Health Behavior to Reduce Risks for Heart Disease and Stroke for African American Men in a Faith-Based Community.

Lee S, Schorr E, Hadidi NN, Kelley R, Treat-Jacobson D, Lindquist R.

J Racial Ethn Health Disparities. 2018 Oct;5(5):1117. doi: 10.1007/s40615-018-0482-1.

PMID:
29582382
44.

DNA nanoparticles are safe and nontoxic in non-human primate eyes.

Kelley RA, Conley SM, Makkia R, Watson JN, Han Z, Cooper MJ, Naash MI.

Int J Nanomedicine. 2018 Mar 8;13:1361-1379. doi: 10.2147/IJN.S157000. eCollection 2018.

45.

Anti-Müllerian hormone overexpression restricts preantral ovarian follicle survival.

Pankhurst MW, Kelley RL, Sanders RL, Woodcock SR, Oorschot DE, Batchelor NJ.

J Endocrinol. 2018 May;237(2):153-163. doi: 10.1530/JOE-18-0005. Epub 2018 Mar 14.

PMID:
29540452
46.

Delayed Presentation of Cecal Perforation With Tension-Free Vaginal Tape.

Mayhew AC, Ford AT, Northington GM, Shaffer VO, Kelley RS.

Obstet Gynecol. 2018 Mar;131(3):499-502. doi: 10.1097/AOG.0000000000002495.

PMID:
29420415
47.

Customized Pessary Fabrication Using Three-Dimensional Printing Technology.

Barsky M, Kelley R, Bhora FY, Hardart A.

Obstet Gynecol. 2018 Mar;131(3):493-497. doi: 10.1097/AOG.0000000000002461.

PMID:
29420400
48.

Implementing Dementia Care Mapping as a practice development tool in dementia care services: a systematic review.

Surr CA, Griffiths AW, Kelley R.

Clin Interv Aging. 2018 Jan 26;13:165-177. doi: 10.2147/CIA.S138836. eCollection 2018. Review.

49.

Power of Peer Support to Change Health Behavior to Reduce Risks for Heart Disease and Stroke for African American Men in a Faith-Based Community.

Lee S, Schorr E, Hadidi NN, Kelley R, Treat-Jacobson D, Lindquist R.

J Racial Ethn Health Disparities. 2018 Oct;5(5):1107-1116. doi: 10.1007/s40615-018-0460-7. Epub 2018 Feb 1. Erratum in: J Racial Ethn Health Disparities. 2018 Mar 26;:.

PMID:
29392680
50.

Clinical skills temporal degradation assessment in undergraduate medical education.

Fisher J, Viscusi R, Ratesic A, Johnstone C, Kelley R, Tegethoff AM, Bates J, Situ-Lacasse EH, Adamas-Rappaport WJ, Amini R.

J Adv Med Educ Prof. 2018 Jan;6(1):1-5.

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