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Items: 1 to 50 of 117

1.

Unequivocal determination of caulamidines A and B: application and validation of new tools in the structure elucidation tool box.

Milanowski DJ, Oku N, Cartner LK, Bokesch HR, Williamson RT, Saurí J, Liu Y, Blinov KA, Ding Y, Li XC, Ferreira D, Walker LA, Khan S, Davies-Coleman MT, Kelley JA, McMahon JB, Martin GE, Gustafson KR.

Chem Sci. 2017 Nov 6;9(2):307-314. doi: 10.1039/c7sc01996c. eCollection 2018 Jan 14.

2.

Exploring the influence of indololactone structure on selectivity for binding to the C1 domains of PKCα, PKCε, and RasGRP.

Elhalem E, Donadío LG, Zhou X, Lewin NE, Garcia LC, Lai CC, Kelley JA, Peach ML, Blumberg PM, Comin MJ.

Bioorg Med Chem. 2017 Jun 15;25(12):2971-2980. doi: 10.1016/j.bmc.2017.03.022. Epub 2017 Mar 10.

3.

Characterization of nitrated sugar alcohols by atmospheric-pressure chemical-ionization mass spectrometry.

Ostrinskaya A, Kelley JA, Kunz RR.

Rapid Commun Mass Spectrom. 2017 Feb 28;31(4):333-343. doi: 10.1002/rcm.7803.

PMID:
27933669
4.

Experimental and Chemoinformatics Study of Tautomerism in a Database of Commercially Available Screening Samples.

Guasch L, Yapamudiyansel W, Peach ML, Kelley JA, Barchi JJ Jr, Nicklaus MC.

J Chem Inf Model. 2016 Nov 28;56(11):2149-2161. Epub 2016 Oct 16.

5.

Reagent approaches for improved detection of chlorate and perchlorate salts via thermal desorption and ionization.

Kelley JA, Ostrinskaya A, Geurtsen G, Kunz RR.

Rapid Commun Mass Spectrom. 2016 Jan 15;30(1):191-8. doi: 10.1002/rcm.7427.

PMID:
26661986
6.

Reactive Species Involved in the Regioselective Photooxidation of Heptamethine Cyanines.

Nani RR, Kelley JA, Ivanic J, Schnermann MJ.

Chem Sci. 2015 Nov 1;6(11):6556-6563. Epub 2015 Aug 18.

7.

Neighbor-directed histidine N (τ)-alkylation: A route to imidazolium-containing phosphopeptide macrocycles.

Qian WJ, Park JE, Grant R, Lai CC, Kelley JA, Yaffe MB, Lee KS, Burke TR Jr.

Biopolymers. 2015 Nov;104(6):663-73. doi: 10.1002/bip.22698.

8.

Mono-anionic phosphopeptides produced by unexpected histidine alkylation exhibit high Plk1 polo-box domain-binding affinities and enhanced antiproliferative effects in HeLa cells.

Qian WJ, Park JE, Lim D, Lai CC, Kelley JA, Park SY, Lee KW, Yaffe MB, Lee KS, Burke TR Jr.

Biopolymers. 2014 Nov;102(6):444-55. doi: 10.1002/bip.22569.

9.

Design and synthesis of Fmoc-Thr[PO(OH)(OPOM)] for the preparation of peptide prodrugs containing phosphothreonine in fully protected form.

Qian WJ, Lai CC, Kelley JA, Burke TR Jr.

Chem Biodivers. 2014 May;11(5):784-91. doi: 10.1002/cbdv.201300202.

10.

Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP.

Garcia LC, Donadío LG, Mann E, Kolusheva S, Kedei N, Lewin NE, Hill CS, Kelsey JS, Yang J, Esch TE, Santos M, Peach ML, Kelley JA, Blumberg PM, Jelinek R, Marquez VE, Comin MJ.

Bioorg Med Chem. 2014 Jun 15;22(12):3123-40. doi: 10.1016/j.bmc.2014.04.024. Epub 2014 Apr 20.

11.

The effect of standing acoustic waves on the formation of laser-induced air plasmas.

Craig SM, Brownell K, O'Leary B, Malfitano C, Kelley JA.

Appl Spectrosc. 2013 Mar;67(3):329-34. doi: 10.1366/12-06652.

PMID:
23452498
12.

Enhanced stereoselectivity of a Cu(II) complex chiral auxiliary in the synthesis of Fmoc-L-γ-carboxyglutamic acid.

Smith DJ, Yap GP, Kelley JA, Schneider JP.

J Org Chem. 2011 Mar 18;76(6):1513-20. doi: 10.1021/jo101940k. Epub 2011 Feb 3.

13.

Using conformationally locked nucleosides to calibrate the anomeric effect: Implications for glycosyl bond stability.

Moon HR, Siddiqui MA, Sun G, Filippov IV, Landsman NA, Lee YC, Adams KM, Barchi JJ, Deschamps JR, Nicklaus MC, Kelley JA, Marquez VE.

Tetrahedron. 2010 Aug 21;66(34):6707-6717.

14.

Inhibition of ABCG2-mediated drug efflux by naphthopyrones from marine crinoids.

Bokesch HR, Cartner LK, Fuller RW, Wilson JA, Henrich CJ, Kelley JA, Gustafson KR, McMahon JB, McKee TC.

Bioorg Med Chem Lett. 2010 Jul 1;20(13):3848-50. doi: 10.1016/j.bmcl.2010.05.057. Epub 2010 May 21.

15.

Academic predictors of success in a nursing program.

Wolkowitz AA, Kelley JA.

J Nurs Educ. 2010 Sep;49(9):498-503. doi: 10.3928/01484834-20100524-09.

PMID:
20509584
16.

Utilization of the coherence function with Welch's method for signal analysis in low resolution laser-induced breakdown spectroscopy.

O'Leary B, Kelley JA.

Appl Spectrosc. 2010 Apr;64(4):370-6. doi: 10.1366/000370210791114257.

PMID:
20412620
17.

INCB16562, a JAK1/2 selective inhibitor, is efficacious against multiple myeloma cells and reverses the protective effects of cytokine and stromal cell support.

Li J, Favata M, Kelley JA, Caulder E, Thomas B, Wen X, Sparks RB, Arvanitis A, Rogers JD, Combs AP, Vaddi K, Solomon KA, Scherle PA, Newton R, Fridman JS.

Neoplasia. 2010 Jan;12(1):28-38.

18.

North- and south-bicyclo[3.1.0]hexene nucleosides: the effect of ring planarity on anti-HIV activity.

Russ PL, Gonzalez-Moa MJ, Vu BC, Sigano DM, Kelley JA, Lai CC, Deschamps JR, Hughes SH, Marquez VE.

ChemMedChem. 2009 Aug;4(8):1354-63. doi: 10.1002/cmdc.200900153.

19.

A novel side-bridged hybrid phosphonate/acetate pendant cyclam: synthesis, characterization, and 64Cu small animal PET imaging.

Boswell CA, Regino CA, Baidoo KE, Wong KJ, Milenic DE, Kelley JA, Lai CC, Brechbiel MW.

Bioorg Med Chem. 2009 Jan 15;17(2):548-52. doi: 10.1016/j.bmc.2008.11.073. Epub 2008 Dec 6.

20.

What are the consequences of freezing the anomeric effect in nucleosides?

Marquez VE, Sun G, Siddiqui MA, Lee YC, Barchi JJ Jr, Filippov IV, Landsman NA, Kelley JA.

Nucleic Acids Symp Ser (Oxf). 2008;(52):543-4. doi: 10.1093/nass/nrn275.

21.

Conformationally constrained analogues of diacylglycerol. 29. Cells sort diacylglycerol-lactone chemical zip codes to produce diverse and selective biological activities.

Duan D, Sigano DM, Kelley JA, Lai CC, Lewin NE, Kedei N, Peach ML, Lee J, Abeyweera TP, Rotenberg SA, Kim H, Kim YH, El Kazzouli S, Chung JU, Young HA, Young MR, Baker A, Colburn NH, Haimovitz-Friedman A, Truman JP, Parrish DA, Deschamps JR, Perry NA, Surawski RJ, Blumberg PM, Marquez VE.

J Med Chem. 2008 Sep 11;51(17):5198-220. doi: 10.1021/jm8001907. Epub 2008 Aug 13.

22.

Synthesis of a cross-bridged cyclam derivative for peptide conjugation and 64Cu radiolabeling.

Boswell CA, Regino CA, Baidoo KE, Wong KJ, Bumb A, Xu H, Milenic DE, Kelley JA, Lai CC, Brechbiel MW.

Bioconjug Chem. 2008 Jul;19(7):1476-84. doi: 10.1021/bc800039e. Epub 2008 Jul 3.

23.

Conformationally constrained analogues of diacylglycerol (DAG). 27. Modulation of membrane translocation of protein kinase C (PKC) isozymes alpha and delta by diacylglycerol lactones (DAG-lactones) containing rigid-rod acyl groups.

Malolanarasimhan K, Kedei N, Sigano DM, Kelley JA, Lai CC, Lewin NE, Surawski RJ, Pavlyukovets VA, Garfield SH, Wincovitch S, Blumberg PM, Marquez VE.

J Med Chem. 2007 Mar 8;50(5):962-78. Epub 2007 Feb 7.

PMID:
17284021
24.

Design and concise synthesis of fully protected analogues of l-gamma-carboxyglutamic acid.

Jiang S, Li P, Lai CC, Kelley JA, Roller PP.

J Org Chem. 2006 Sep 15;71(19):7307-14.

PMID:
16958524
25.

Mining the NCI antiviral compounds for HIV-1 integrase inhibitors.

Deng J, Kelley JA, Barchi JJ, Sanchez T, Dayam R, Pommier Y, Neamati N.

Bioorg Med Chem. 2006 Jun 1;14(11):3785-92. Epub 2006 Feb 7.

PMID:
16460953
26.

Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy.

Marquez VE, Kelley JA, Agbaria R, Ben-Kasus T, Cheng JC, Yoo CB, Jones PA.

Ann N Y Acad Sci. 2005 Nov;1058:246-54. Review.

PMID:
16394141
27.

Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology.

Marquez VE, Barchi JJ Jr, Kelley JA, Rao KV, Agbaria R, Ben-Kasus T, Cheng JC, Yoo CB, Jones PA.

Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):305-18. Review.

PMID:
16247946
28.

Proposed nurse educator competencies: development and validation of a model.

Davis D, Stullenbarger E, Dearman C, Kelley JA.

Nurs Outlook. 2005 Jul-Aug;53(4):206-11.

PMID:
16115514
29.

Interleukin 6 supports the maintenance of p53 tumor suppressor gene promoter methylation.

Hodge DR, Peng B, Cherry JC, Hurt EM, Fox SD, Kelley JA, Munroe DJ, Farrar WL.

Cancer Res. 2005 Jun 1;65(11):4673-82.

30.

Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells.

Ben-Kasus T, Ben-Zvi Z, Marquez VE, Kelley JA, Agbaria R.

Biochem Pharmacol. 2005 Jul 1;70(1):121-33.

PMID:
15885659
31.

Dynamics of the antiviral activity of N-methanocarbathymidine against herpes simplex virus type 1 in cell culture.

Huleihel M, Talishanisky M, Ford H Jr, Marquez VE, Kelley JA, Johns DG, Agbaria R.

Int J Antimicrob Agents. 2005 May;25(5):427-32.

PMID:
15848299
32.

Synthesis and biological study of a flavone acetic acid analogue containing an azido reporting group designed as a multifunctional binding site probe.

Malolanarasimhan K, Lai CC, Kelley JA, Iaccarino L, Reynolds D, Young HA, Marquez VE.

Bioorg Med Chem. 2005 Apr 15;13(8):2717-22.

PMID:
15781383
33.

Microarray analysis of epigenetic silencing of gene expression in the KAS-6/1 multiple myeloma cell line.

Pompeia C, Hodge DR, Plass C, Wu YZ, Marquez VE, Kelley JA, Farrar WL.

Cancer Res. 2004 May 15;64(10):3465-73.

34.

Macrocyclization in the design of non-phosphorus-containing Grb2 SH2 domain-binding ligands.

Shi ZD, Wei CQ, Lee K, Liu H, Zhang M, Araki T, Roberts LR, Worthy KM, Fisher RJ, Neel BG, Kelley JA, Yang D, Burke TR Jr.

J Med Chem. 2004 Apr 8;47(8):2166-9.

PMID:
15056012
35.

Potent inhibition of HhaI DNA methylase by the aglycon of 2-(1H)-pyrimidinone riboside (zebularine) at the GCGC recognition domain.

Marquez VE, Eritja R, Kelley JA, Vanbemmel D, Christman JK.

Ann N Y Acad Sci. 2003 Dec;1002:154-64.

PMID:
14751833
36.

Caulibugulones A-F, novel cytotoxic isoquinoline quinones and iminoquinones from the marine bryozoan Caulibugula intermis.

Milanowski DJ, Gustafson KR, Kelley JA, McMahon JB.

J Nat Prod. 2004 Jan;67(1):70-3.

PMID:
14738389
37.

Synthesis and conformational analysis of a locked analogue of carbovir built on a bicyclo[3.1.0]hex-2-enyl template.

Choi Y, Sun G, George C, Nicklaus MC, Kelley JA, Marquez VE.

Nucleosides Nucleotides Nucleic Acids. 2003 Dec;22(12):2077-91.

PMID:
14714758
39.

Absence of post-translational aspartyl beta-hydroxylation of epidermal growth factor domains in mice leads to developmental defects and an increased incidence of intestinal neoplasia.

Dinchuk JE, Focht RJ, Kelley JA, Henderson NL, Zolotarjova NI, Wynn R, Neff NT, Link J, Huber RM, Burn TC, Rupar MJ, Cunningham MR, Selling BH, Ma J, Stern AA, Hollis GF, Stein RB, Friedman PA.

J Biol Chem. 2002 Apr 12;277(15):12970-7. Epub 2001 Dec 31.

40.

Biosynthetic ganciclovir triphosphate: its isolation and characterization from ganciclovir-treated herpes simplex thymidine kinase-transduced murine cells.

Agbaria R, Candotti F, Kelley JA, Hao Z, Johns DG, Cooney DA, Blaese RM, Ford H Jr.

Biochem Biophys Res Commun. 2001 Nov 30;289(2):525-30.

PMID:
11716505
41.
42.

Fluorometric determination of 2'-beta-fluoro-2',3'-dideoxyadenosine 5'-triphosphate, the active metabolite of a new anti-human immunodeficiency virus drug, in human lymphocytes.

Dai F, Kelley JA, Zhang H, Malinowski N, Kavlick MF, Lietzau J, Welles L, Yarchoan R, Ford H Jr.

Anal Biochem. 2001 Jan 1;288(1):52-61.

PMID:
11141306
43.
44.

Identification of HIV-1 integrase inhibitors via three-dimensional database searching using ASV and HIV-1 integrases as targets.

Chen IJ, Neamati N, Nicklaus MC, Orr A, Anderson L, Barchi JJ Jr, Kelley JA, Pommier Y, MacKerell AD Jr.

Bioorg Med Chem. 2000 Oct;8(10):2385-98.

PMID:
11058033
45.

Preparation of aryl isothiocyanates via protected phenylthiocarbamates and application to the synthesis of caffeic acid (4-isothiocyanato)phenyl ester.

Zhang X, Lee YK, Kelley JA, Burke TR Jr.

J Org Chem. 2000 Sep 22;65(19):6237-40. No abstract available.

PMID:
10987967
46.

The "beta-fluorine effect" in the non-metal hydride radical deoxygenation of fluorine-containing nucleoside xanthates.

Siddiqui MA, Driscoll JS, Abushanab E, Kelley JA, Barchi JJ Jr, Marquez VE.

Nucleosides Nucleotides Nucleic Acids. 2000 Jan-Feb;19(1-2):1-12.

PMID:
10772699
47.

Isolating the spectroscopic signature of a hydration shell with the use of clusters: superoxide tetrahydrate

Weber JM, Kelley JA, Nielsen SB, Ayotte P, Johnson MA.

Science. 2000 Mar 31;287(5462):2461-3.

48.

2'-beta-fluoro-2',3'-dideoxyadenosine, lodenosine, in rhesus monkeys: plasma and cerebrospinal fluid pharmacokinetics and urinary disposition.

Roth JS, McCully CM, Balis FM, Poplack DG, Kelley JA.

Drug Metab Dispos. 1999 Oct;27(10):1128-32.

PMID:
10497138
49.

Determination of 2'-beta-fluoro-2',3'-dideoxyadenosine, an experimental anti-AIDS drug, in human plasma by high-performance liquid chromatography.

Roth JS, Ford H Jr, Tanaka M, Mitsuya H, Kelley JA.

J Chromatogr B Biomed Sci Appl. 1998 Aug 7;712(1-2):199-210.

PMID:
9698243
50.

A prearranged mentorship program: can it work long distance?

Owens BH, Herrick CA, Kelley JA.

J Prof Nurs. 1998 Mar-Apr;14(2):78-84.

PMID:
9549209

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